Gazi University Dspace
Not a member yet
26981 research outputs found
Sort by
EMERGENCY SIMULATION IN A LONG HIGHWAY TUNNEL
In regions that are difficult to overcome geographically in road
transport, tunnels both shorten the road to be covered and save fuel. It
is the worst scenario that a vehicle can burn in a tunnel. There have
been major tunnel fires in the world that have resulted in people's
lives. In our country, long highway tunnels such as the Ovit, Kop and
Zigana tunnels are being built. In this study, emergency modeling was
carried out for vehicle fire (30 MW) in a long road tunnel (14.5 km).
The critical point for the emergency was determined and the 1000 m long
region was examined on a scale of 1/100. Ansys Fluent was used in the
study. Turbulent flow conditions are taken into account. Temperature
distribution, carbon monoxide (CO) emission distribution and velocity
distributions in the region where the fire is located were examined.
Results are given in graphs and interpreted. When the temperature values
are examined, the average temperature values in the fire zone were
obtained above 400 K in the first 30 m. It was obtained that the CO
values did not fall below 400 ppm until the firing shaft, especially in
the first 50 m, above 1000 ppm on average
Which out-of-office measurement technique should be used for diagnosing hypertension in prehypertensives?
Hypertension (HT) is diagnosed with high office blood pressure (BP),
although confirmation with the addition of out-of-office measurements is
currently recommended. However, insufficient data are available
concerning the use of out-of-office BP measurement techniques for the
diagnosis of HT in the prehypertensive population. The aim of the
present study was to determine which out-of-office measurements yielded
earlier and more frequent detection of development of HT in
prehypertensive patients. Two hundred seven prehypertensive patients
under monitoring in the Cappadocia cohort were included in the study.
Office BP was measured five times at 1-min intervals, followed by 24-h
ambulatory BP monitoring (24-h ABPM). Home BP measurement (HBPM) was
performed five times, at the same times in the morning and evening, at
1-min intervals for 1 week. The same procedure was carried out at
4-6-month intervals for \~{}2 years. HT was diagnosed in 25.6\% of
subjects, masked HT in 11.1\%, and white coat HT in 2.9\%, while 23.7\%
remained prehypertensive and 36.7\% became normotensive. Briefly, 56.6\%
of the patients with HT were diagnosed with office plus 24-h ABPM,
13.2\% with office plus HBPM, and 30.2\% with office plus HBPM and 24-h
ABPM. Office with 24-h ABPM yielded statistically significantly more
diagnoses (p < 0.001). In conclusion, our prospective observational
study evaluated the usefulness of out-of-office BP measurements in
confirming diagnosis of HT in prehypertensive patients. The findings
show that 24-h ABPM detected HT earlier and more frequently in this
high-risk population
CVD Yöntemi ile Karbon Katkılanmış Bor Kullanılarak Üretilen MgB2’nin Mikrosertlik Özelliklerinin İncelenmesi
Micromonospora deserti sp. nov., isolated from the Karakum Desert
An isolate, 13K206(T), with typical morphological characteristics of the
genus Micromonospora was obtained during a study searching for novel
actinobacteria with biosynthetic potential from the Karakum Desert. A
polyphasic approach was adopted to determine taxonomic affiliation of
the strain. The strain showed chemotaxonomical properties consistent
with its classification in the genus Micromonospora such as meso- and
3-OH-A(2)pm in the cell-wall peptidoglycan, xylose in whole-cell
hydrolysate and diphosphatidylglycerol, phosphatidylethanolamine and
phosphatidylinositol as major polar lipids. The results of phylogenetic
analysis based on 16S rRNA gene sequences revealed that the strain was
closely related to `Micromonospora spongicola' S3-1(T), Micromonospora
nigra DSM 43818(T) and Micromonospora yasonensis DS3186(T) with sequence
similarities of 98.6, 98.5 and 98.4 \%, respectively. Digital DNA-DNA
hybridization and average nucleotide identity analyses in addition to
gyrB gene analysis confirmed the assignment of the strain to a novel
species within the genus Micromonospora for which the name
Micromonospora deserti sp. nov. is proposed. The type strain is
13K206(T) (=JCM 32583(T)=DSM 107532(T)). The DNA G+C content of the type
strain is 72.4 mol\%
Quality-of-life Evaluation of Healthy Siblings of Children with Chronic Illness
Background: Chronic disease of children can cause changes in the
health-related quality of life (HrQoL) of the family members.
Aims: To evaluate the HrQoL of healthy siblings of children with chronic
disease.
Study Design: Cross-sectional study.
Methods: The study included healthy sibling of children with chronic
disease (cerebral palsy, epilepsy; diabetes, celiac disease,
hematologic/ oncologic disease, or asthma) and healthy sibling of
healthy children to evaluate the quality of life. We used the Pediatric
Quality of Life Inventory questionnaire; the physical health and
psychosocial health scores were calculated using the responses of the
sibling and parent. The primary endpoint was the comparison of HrQoL
scores of healthy siblings of children with chronic disease and that of
healthy siblings of healthy children.
Results: This study included a respective healthy sibling of 191
children with chronic disease and healthy sibling of 100 healthy
children. The physical health, psychosocial health, and total health
scores of healthy siblings of children with chronic disease were
significantly lower than that of healthy siblings of healthy children
(p<0.001). Among the healthy siblings of children with chronic disease,
the lowest psychosocial health score was found in the siblings of
children with cerebral palsy, hematologic/oncologic disease. and asthma
(p<0.001). The global impact on the quality of life for healthy siblings
of children with chronic disease was significantly higher in the
self-report of the children than that of the parents (30.4\% versus
15.1\%, p<0.05).
Conclusion: Most healthy siblings of children with chronic disease are
physically and psychosocially affected and there is low parental
awareness of this condition. This can increase the risk of emotional
neglect and abuse of these children. Therefore. special support programs
are needed for the families of children with chronic diseases