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Guideline on preterm labor and delivery by the society of specialists in perinatology (perinatoloji uzmanları derneği-puder), Turkey
No full textConceptual understanding levels of students with different cognitive styles: An evaluation in terms of different measurement techniques [Farklı bilişsel stillere sahip öğrencilerin kavramsal anlama düzeyleri: Farklı ölçme teknikleri açısından bir değerlendirme]
No full textDistal oblique metatarsal osteotomy technique in hallux valgus deformity: Clinical and radiological results
No full textObjectives: This study aims to evaluate the radiological and functional
outcomes of hallux valgus patients treated with distal oblique
metatarsal osteotomy technique.
Patients and methods: Twenty-six feet of 22 patients (4 males, 18
females; mean age 46.2 +/- 18 years: range, 16 to 70 years) who were
diagnosed as hallux valgus between March 2013 and April 2016 and who
underwent distal oblique metatarsal osteotomy were included in this
retrospective study. American Orthopedic Foot and Ankle Society/Hallux
Metatarsophalangeal-Interphalangeal Scale (AOFASIHMIS) was used for
clinical and functional evaluation. The hallux valgus angle (HVA),
intermetatarsal angle (IMA), distal metatarsal articular angle (DMAA),
sesamoid position, first metatarsal length and forefoot bone and soft
tissue width were measured for radiological evaluation.
Results: The mean follow-up time was 33.1 +/- 9.8 months. The AOFAS/HMIS
score increased significantly postoperatively (p=0.001). In the footwear
section of the AOFAS/HMIS, the median preoperative score of 5 (range.
0-5) increased to 10 (range. 5-10) at the postoperative period
(p=0.001). Hallux valgus angle, IMA, DMAA, and first metatarsal length
significantly decreased when compared to preoperative measurements.
Forefoot bone width also decreased significantly from 9.3 cm (range,
7.5-11.5 cm) to 8.8 cm (6.8-10.3 cm) (p=0.001).
Conclusion: Distal oblique metatarsal osteotomy is a safe method for
hallux valgus deformity. Forefoot width reduction. decrease of soft
tissue tension. sesamoid reduction, and plantar fascia relaxation are
the crucial benefits of this method
Numerıcal Analysıs Of The Dıstrıbutıon Of Nanopartıcles In The Treatment Of Hyperthermıa Of Tumors
No full textHipertermi tedavisi kanserli dokuyu yok etmek için etkili bir tedavi yöntemidir. Bu yöntemde çevredeki sağlıklı dokuda minimum zarar oluşturmak suretiyle tümör sıcaklığı kanserli dokuyu öldürecek kadar arttırılır. Kanserli dokuları yok etmek için yapılan hipertermi tedavisi habis (ölümcül) tümörler için oldukça etkili bir tedavi yöntemidir. Hipertermi tedavisinin amacı tümör sıcaklığını üniform ve hızlı bir şekilde yükseltmek ve çevredeki sağlıklı doku hasarını en aza indirerek kanserli dokuları en kısa sürede yok etmektir. Bunun için üniform olarak tümörlü dokunun ısıtılıp, kısa sürede yok edilmesi için doku içerisine enjekte edilen nanopartiküllerden yararlanılır. Bu çalışmanın amacı, dünyada tıbbi uygulaması olan fakat ülkemizde henüz uygulanmayan hipertermi tedavisindeki sürecin bir parçası olan, tümör içerisine enjekte edilen nanopartikülün tümörlü ve sağlıklı dokudaki optimal difüzyon süresine ve parçacık hız dağılımına olan etkisini sayısal olarak incelemektir. Nanopartikül difüzyonu iki boyutlu olarak incelenmiştir. Çalışma sonlu elemanlar yöntemi kullanılarak gerçekleştirilmiştir. Sağlıklı doku ve tümörün dairesel olduğu kabul edilmiştir. Sayısal çalışmada incelenen parametreler doku içerisine enjekte edilen partikülün çapı, dokunun (akışkanın) sıcaklığı, akışkanın viskozitesi ve partikülün doku içerisindeki difüzyonu için geçen zamandır. Enjekte edilen partikül çapı olarak 100, 200, 400, 600 ve 800 nanometre seçilmiştir. Akışkan sıcaklığı olarak ise 310, 313 ve 316 K değerleri alınmıştır. Akışkan viskozitesi olarak 110-5, 210-5, 310-5, 410-5 ve 510-5 Pas seçilmiştir. Nanopartikülün tümörlü ve sağlıklı dokudaki dağılımı 0, 15, 30, 60, 100 ve 300 s için incelenmiştir. Sonuçlar enjekte edilen partikül çapının ve akışkan viskozitesinin artması ile doku içerisindeki nanopartikül konsantrasyonunun arttığını göstermiştir. Fakat, artan akışkan sıcaklığı ile ise partikül konsantrasyonunun azaldığı görülmüştür. Ayrıca, artan difüzyon süresi ile partikül konsantrasyonunun arttığı gözlenmiştir. Mevcut çalışma sonuçlarının bilim insanlarına ve doktorlara kanser tedavisinde yardımcı olacağı düşünülmektedir.Hyperthermia treatment is an effective treatment method for destroying cancerous tissue. In this method, the tumor temperature is increased so as to kill the cancerous tissue by creating minimal damage to the surrounding healthy tissue. Treatment of hyperthermia to destroy cancerous tissues is a highly effective treatment for malignant tumors. The aim of hyperthermia treatment is to increase tumor temperature uniformly and quickly to eliminate cancerous tissues as soon as possible by minimizing the damage to surrounding healthy tissue. For this purpose, nanoparticles injected into tissue are used to heat the tumor tissue uniformly and to eliminate tumor in a short time. The aim of this study is to quantitatively investigate the effect of nanoparticle injected into the tumor on optimal diffusion time and particle velocity distribution in tumor and healthy tissue, which is a part of the treatment of hyperthermia, which has medical applications in the world but has not been applied in our country yet. Two dimensional nanoparticle diffusion is investigated. The study is carried out using finite element method. Healthy tissue and tumor are considered as circular. The parameters studied in the numerical study are the diameter of the particle injected into the tissue, the temperature of the tissue (fluid), the viscosity of the fluid, and the time taken for the diffusion of the particle in the tissue. 100, 200, 400, 600 and 800 nanometers are selected as the injected particle diameter. 310, 313 and 316 K values are taken as the fluid temperature. Fluid viscosity is selected as 110-5, 210-5, 310-5, 410-5 and 510-5 Pas. The distribution of nanoparticles in tumor and healthy tissue is examined for 0, 15, 30, 60, 100 and 300 s. The results have shown that the nanoparticle concentration in the tissue increases with increasing injected particle diameter and fluid viscosity. However, it has been observed that particle concentration decreases with increasing fluid temperature. It is also observed that particle concentration increases with increasing diffusion time. The results of the present study are thought to help scientists and doctors in the treatment of cancer
Evaluation of asymptomatic bacteriuria and urinary tract infection in patients with primary sjögren’s syndrome
No full textNovel coronavirus disease (COVID-19) in children
No full textCoronavirus disease (COVID-19) was firstly reported at the end of 2019.
The disease rapidly spread all around the world in a few months and was
declared a worldwide pandemic by WHO in March 2020. By April 9, there
were 1,436,198 confirmed COVID-19 cases in the world, nearly with 6\%
mortality rate. This novel infectious disease causes respiratory tract
illness that may generally occur as mild upper respiratory tract disease
or pneumonia. In older patients and/or patients with underlying
conditions, it may result in acute respiratory distress syndrome, multi
organ failure and even death. According to the current literature,
children account approximately for 1\%-5\% of diagnosed COVID-19 cases.
Generally, COVID-19 seems to be a less severe disease for children than
adults. Approximately 90\% of pediatric patients are diagnosed as
asymptomatic, mild, or moderate disease. However, up to 6.7\% of cases
may be severe. Severe illness is generally seen in patients smaller than
1 year of age and patients who have underlying disesases. The
epidemiological and clinical patterns of COVID-19 and treatment
approaches in pediatric patients still remain unclear although many
pediatric reports are published. This review aims to summarize the
current epidemics, clinical presentations, diagnosis, and treatment of
COVID-19 in pediatric patients
Sosyal Bilimler Lisesi Öğrencilerinin İngilizce Öğrenme Motivasyonlarını Azaltan Faktörler
No full textSeasonal variations of patients presenting dyspnea to emergency departments in Europe: Results from the EURODEM Study
No full textBackground/aim: To describe seasonal variations in epidemiology,
management, and short-term outcomes of patients in Europe presenting to
an emergency department (ED) with a main complaint of dyspnea.
Materials and methods: An observational prospective cohort study was
performed in 66 European EDs which included consecutive patients
presenting to EDs with dyspnea as the main complaint during 3 72-h study
periods. Data were collected on demographics, comorbidities, chronic
treatment, prehospital treatment, mode of arrival of patient to ED,
clinical signs at admission, treatment in the ED, ED diagnosis,
discharge from El), and in-hospital outcome.
Results: The study included 2524 patients with a median age of 69
(53-80) years old. Of the patients presented, 991 (39.3\%) were in
autumn, 849 (33.6\%) were in spring, and 48 (27.1\%) were in winter. The
winter population was significantly older (P < 0.001) and had a lower
rate of ambulance arrival to ED (P < 0.001). In the winter period, there
was a higher rate for lower respiratory tract infection (35.1\%), and
patients were more hypertensive, more hypoxic, and more
hyper/hypothermic compared to other seasons. The ED mortality was about
1\% and, in hospital, mortality for admitted patients was 7.4\%.
Conclusion: The analytic method and the outcome of this study may help
to guide the allocation of ED resources more efficiently and to
recommend seasonal ED management protocols based on the seasonal trend
of dyspneic patients
