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Antimicrobial surgical prophylaxis: Still an issue in paediatrics
Objectives: Antimicrobial prophylaxis (AP) is an important means of
reducing surgical site infections. The goal of this study was to
evaluate the perioperative AP in paediatric practice and its compliance
with surgical prophylaxis guidelines.
Methods: A prospective study was conducted at Gazi University Faculty of
Medicine, between September 2015 and April 2016. Paediatric patients who
underwent surgical procedures were included in the study. Surgical AP
was evaluated.
Results: During the entire study period, 466 children underwent surgery
at our centre; 433 (92.7\%) received antimicrobial prophylaxis. Overall
adherence to the guidelines regarding surgical prophylaxis was 22.1\%.
The rate of administration of surgical prophylaxis was significantly
lower, and the duration was shorter when the surgical procedure was
clean (P = 0.002). When the duration of the procedure was longer, the
rate of administration of prophylaxis was higher (P = 0.000). The
duration of postoperative prophylaxis was longer than recommended in
72.2\% of the patients. In the multivariate analysis, application errors
increased with longer surgical time (P = 0.01, OR 2.18, 95\% CI
1.19-4.03).
Conclusions: High rates of misapplication of antimicrobial surgical
prophylaxis were observed in this study. Awareness and usage of
guidelines should be encouraged. The education of clinicians should be
supported by studies regarding surgical prophylaxis in children. (C)
2020 The Authors. Published by Elsevier Ltd on behalf of International
Society for Antimicrobial Chemotherapy
Stage predictivity of neutrophil/lymphocyte and platelet/lymphocyte ratios in pancreatic neuroendocrine tumors
Impact of the demographic and aetiological factors and intraoperative findings on postoperative outcomes in chronic otitis media surgery
Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
Neonatal Screening for Congenital Adrenal Hyperplasia in Turkey: Outcomes of Extended Pilot Study in 241,083 Infants
A case of pregnancy and lactation associated osteoporosis in the third pregnancy; robust response to teriparatide despite delayed administration
The evaluation of hydroxyapatite synthesized from waste eggshell in the adsorption of Remazol N.Blue RGB dye
In this study, hydroxyapatite material was prepared for the removal of
Remazol N.Blue RGB (RB203) from waters. In the synthesis of
hydroxyapatite material, waste hen's eggshell was evaluated as calcium
source. Synthesis of hydroxyapatites was performed at three different pH
values (pH 9, 10 and 11) using precipitation method. Before and after
calcination of eggshells, XRF, XRD and SEM analysis were carried out.
Synthesized hydroxyapatites were characterized by TGA-DTA, XRD and FTIR
analysis. At the end of the characterization studies, hydroxyapatite
structure was obtained better in pH 10 medium, and adsorption studies
were carried out with the material prepared at this pH value. The
effects of pH (2-12), amount of sorbent (2-10 g/L) and concentration of
dye (25-200 mg/L) on adsorption of RB203 using hydroxyapatite were
examined. In order to determine the mechanism of adsorption, the
Langmuir, Freundlich, Temkin and Henry isoterm equations were used.
Comparing the adsorption isotherms in terms of correlation coefficients
(R-2), it was seen that the Langmuir, Freundlich and Temkin isotherm
models were in good agreement with the experimental data. The highest
adsorption capacity obtained with the Langmuir isotherm model was 27.93
mg/g. In order to examine the adsorption kinetics, the pseudo-first and
the second order kinetic equations were used. The results of adsorption
kinetics show that the adsorption of RB203 with hydroxyapatite was
better expressed by the pseudo-second order kinetic equation. This study
shows that the hydroxyapatite synthesized from waste calcined eggshell
is a promising sorbent for adsorption of dye