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Stationarity or nonlinear nonstationarity? assessing standard duration extreme rainfall under türkiye's complex topography and climate variability
No full textThe impact of climate change on extreme rainfall regimes requires a reassessment of the design processes of traditional hydrological structures. For this purpose, conducting an in-depth analysis of the nonstationary nature of extreme rainfall in regions with complex topography and climate is of great importance. This study examines the stationary and nonstationary states of standard duration (5 min-24 h) annual maximum rainfall data across T & uuml;rkiye. For this purpose, the intensity-duration-frequency relationship was analyzed using data at 100 homogeneous stations during 1980-2020. The analyses were performed using the generalized extreme value (GEV) distribution with eight linear and non linear location and scale parameters, based on stationary and nonstationary models. Time was included as a covariate in nonstationary models. The corrected akaike information criterion and likelihood ratio test were used to select the appropriate GEV distribution. Findings indicate that stationarity is generally dominant, but nonstationarity is relatively higher in a nonlinear manner in cold climates and complex topography. The effect of location and scale parameters was found to be individual in the short duration and combined in the long duration. It was observed that nonstationarity was relatively higher in complex topography than in flatter regions up to 8 h. Still, the diversity of nonlinear models decreased over the long duration. In conclusion, this study emphasizes the need to consider nonstationary approaches in designing hydrological structures, especially in climate change
Psychometric evaluation of the Turkish version of the health protection behavior scale
No full textThis study aimed to evaluate the validity and reliability of the Turkish version of the Health Protection Behavior Scale (HPBS). The study was conducted using a two-stage cross-cultural research design in accordance with STROBE guidelines. Data were analyzed using descriptive statistics and exploratory factor analysis (EFA), without performing confirmatory factor analysis (CFA) to avoid the use of the same dataset for model derivation and validation. The overall Cronbach's alpha for the scale was 0.851, indicating high internal consistency. In terms of construct validity, the Healthy Lifestyle Behaviors Scale II and the WHOQOL-BREF showed strong and moderate positive correlations, respectively (p < 0.05). The psychometric properties of the Turkish version of the HPBS are generally good and acceptable
Polyarteritis nodosa with isolated organ involvement requiring resection in the genitourinary system
No full textPolyarteritis nodosa (PAN) is a necrotizing vasculitis of medium-sized arteries that is classically described as a multisystem disease. However, PAN may rarely present with isolated organ involvement, occasionally leading to irreversible organ loss before a definitive diagnosis is established. Data on such presentations remain limited and are largely confined to isolated case reports. We retrospectively evaluated eight patients diagnosed with PAN from multiple centers, focusing on clinical presentation, imaging findings, serological results, histopathological features, treatment approaches, and outcomes. The cohort included six women and two men, with ages ranging from 25 to 76 years. Clinical presentation was highly heterogeneous and frequently dominated by lifethreatening genitourinary events, including massive renal hemorrhage, retroperitoneal hematoma, renovascular disease with aneurysm formation and infarction, and acute testicular pain and swelling. Five of the eight patients were classified as having isolated, single-organ PAN, predominantly involving the kidney and, less frequently, the testis. In these patients, organ loss was often the event that led to definitive diagnosis. Imaging findings supported vascular patterns consistent with PAN, including hematoma, arterial stenosis, aneurysmal changes, and ischemic sequelae. Serological evaluation was largely nondiagnostic, with predominant ANCA negativity. Histopathological examination consistently demonstrated necrotizing arteritis of medium-sized arteries with fibrinoid necrosis, thrombosis, and transmural inflammation, without glomerular or granulomatous involvement. Multisystem disease was identified in three patients, including one fatal presentation diagnosed at autopsy. This multicenter case series highlights isolated-organ PAN as a rare but clinically significant presentation, frequently recognized only after catastrophic vascular complications result in resection. Our findings emphasize the pivotal role of surgical pathology and clinicopathological correlation in establishing the diagnosis and underscore the need to consider PAN in unexplained renal or testicular vascular catastrophes, even in the absence of classic systemic features
The turkish efl teacher profile: Insights into personality, mindfulness, classroom management anxiety, and instructional methods
No full textThis study aimed to examine the personality traits, English language teaching methods, classroom management anxiety, and mindfulness levels of Turkish English as foreign language teachers to represent their profiles by adopting a whole teacher approach. This descriptive study followed a mixed-methods explanatory sequential design, including both qualitative and quantitative methods. Accordingly, the Big Five Inventory, Classroom Management Anxiety Scale, Language Teaching Methods Scale, and Freiburg Mindfulness Inventory were applied to 400 participants from different teaching contexts. Following this, semi-structured interviews were conducted with 34 participants. The results showed that Turkish EFL teachers were mostly agreeable, preferred active teaching methods, had high levels of classroom management anxiety, and were moderately mindful. Based on the inferential analyses, while the male teachers were more mindful, the female teachers who were found to be more neurotic preferred to use active teaching methods more. The findings suggest the need for targeted support in classroom management anxiety and mindfulness training for teachers. The gender differences highlight the importance of personalized professional development to address teachers' unique needs and improve overall teaching effectiveness. Since the teachers who were willing to participate in projects were more extravert and preferred active teaching methods more, project participation should be encouraged
Lhc and dark matter implications of t-b-τ yukawa unification in split susy guts
No full textWe investigate a grand unification inspired version of the minimal supersymmetric standard model (MSSM) based on a left-right symmetric 4-2-2 gauge group, incorporating Yukawa coupling unification and current phenomenological constraints. Utilizing a split soft supersymmetry-breaking parameter space motivated by flavor symmetries, we analyze the implications of recent results from ATLAS, CMS, LHCb, and dark matter direct detection experiments. Our numerical scans, conducted with SARAH and SPheno, identify viable low-energy regions consistent with third-generation Yukawa unification, the observed Higgs boson mass, dark matter relic density, and flavor observables such as B-* Xs gamma, Bs-* mu+mu- and Bu-* tau nu tau. Our findings suggest that while current bounds severely constrain much of the MSSM-like parameter space, substantial regions remain experimentally viable and testable in the ongoing LHC run and next-generation dark matter experiments
Exploring the link between the big five traits and sofalizing behavior among filipino young adults
No full textSocial media has revolutionized our communication ability, bridging geographical boundaries, time differences, and language barriers to facilitate interactions of all kinds. The term "sofalizing" has emerged in response to the growing prevalence of online social media platforms, referring to people interacting with others electronically rather than meeting in person. Exploring the role of personality traits in individuals' proclivities towards online socializing is an under-examined research area, and the Five-Factor Model may provide insight into people's motivations for connecting through virtual environments. Thus, this study used explanatory sequential mixed-method research to examine the relationship between the Big Five personality traits and sofalizing behavior among 475 young Filipino adults aged 18 to 24. The quantitative phase one was a predictive, cross-sectional design, while the qualitative phase two took a phenomenological approach to elicit a deeper understanding of the research problem. Results of the quantitative phase show that neuroticism and openness to experience traits are positively associated, while extraversion is negatively related to sofalizing behavior. As such, Filipino young adults whose personality profiles are more neurotic, introverted, and open to experience would likely sofalize. Our phenomenological inquiry further supported these results with key themes: neuroticism (impact on social connectivity, withdrawal and online presence, online adaptation to stress and anxiety); introversion (comfort in online socialization, emotional responses to socialization, regulation and management of social engagement, social connection and integration); openness to experience (digital exploration driven, dynamics of online social preferences, engagement with content and community).University of Santo Toma
Drilling behavior and tool wear mechanisms of rock wool fiber reinforced pa6 composites
No full textThis study investigates the drilling performance of Polyamide 6 (PA6) composites reinforced with 30 wt% rock wool mineral fiber. The composite plates were fabricated via twin-screw extrusion and injection molding. Drilling experiments were performed on a 3-axis CNC machine using HSS, TiN-coated HSS, and Carbide bits to evaluate delamination, surface roughness (mu m), and thrust force. Results indicated that higher cutting speeds generally reduced delamination by enhancing bit stability, whereas increased feed rates raised surface roughness due to higher cutting forces and vibrations. Specifically, at 20 m/min cutting speed and 0.1 mm/rev feed rate, the carbide drill bit achieved the lowest delamination factor (5.115) compared to HSS (5.23). Among the tested tools, carbide bits demonstrated the most effective performance regarding initial hole quality and delamination control. While advantageous for structural integrity, further quantitative research on wear progression is required to comprehensively evaluate long-term tool life
Biomedical potential of novel copper(II) complexes: From synthesis and characterization to biointeraction profiles and molecular docking approaches
No full textIn recent years, there has been a growing interest in the synthesis of novel compounds with medicinal potential, particularly those exhibiting antioxidant properties, due to their ability to delay, prevent, or eliminate oxidative damage in target cells. In this study, synthesis and comprehensive characterization of three novel copper(II) complexes, [Cu(L1)(phen)] (1), [Cu(L1)(py-phen)] (2) and [Cu(L2)(py-phen)] (3),-featuring Schiff base ligands derived from 5-chlorosalicylaldehyde and valine (L1)/glycine (L2), phen: 1,10-phenanthroline, py-phen: pyr-azino[2,3-f][1,10]phenanthroline-were carried out using electronic absorption spectroscopy, CHN analysis, FTIR, ESI-MS, and X-ray diffraction. Electronic absorption and fluorescence spectroscopy were employed to investigate the interactions between the complexes 1-3 and CT-DNA, trypsin, and urease. The complexes 1-3 were found to bind CT-DNA through minor groove interaction, while their fluorescence quenching with trypsin and urease proceeded via a static mechanism. To better understand the molecular basis of these biological effects, molecular docking simulations were employed to evaluate the binding affinities and interaction profiles of the complexes 1-3 against three biologically relevant macromolecular targets: B-DNA, trypsin, and urease. The docking results revealed high binding affinities, particularly toward DNA, and moderate interactions with trypsin and urease. These findings highlight the role of non-classical interactions such as it-anion, it-sulphur, it-it stacking, and carbon-hydrogen bonds in stabilizing the complexes 1-3 within biologically relevant binding sites. Importantly, the complexes 1-3 preferentially engaged in minor groove binding to DNA and occupied catalytic clefts in the enzymes without directly interfering with key active residues. The docking results provide a molecular basis for the observed or anticipated biological activities and support the potential of the complexes 1-3 as candidates for further pharmacological evaluation. In vitro assessment of the complexes' antioxidant activity revealed a moderate scavenging efficiency. The findings of this study deepen the understanding of the complexes 1-3's interactions with enzymes and emphasize their value in biomedical and pharmaceutical research
European union values in teaching and learning in higher education: A bibliometric analysis
No full textThis study explores how the fundamental values of the European Union (EU), namely human rights, freedom, human dignity, the rule of law, democracy, and equality, are addressed in higher education through a bibliometric analysis. Drawing on 321 documents indexed in the Web of Science Core Collection, the study analyses publication trends, assesses the performance of authors, sources, and documents, and examines collaborative and conceptual structures within the field. Conceptually, the study situates EU values pedagogy within the broader literature on values education and citizenship education in higher education. The findings reveal a growing body of research, highlight thematic imbalances, such as the relative underrepresentation of human dignity and the rule of law, and point to limited international collaboration. Through the mapping of this fragmented and multidisciplinary field, the study provides a structured overview of research on democratic education and EU values pedagogy, offering guidance for future scholarly work.'EmbED-EU: Embedding EU values in teaching and learning in higher education'
2023-1-NL01-KA220-HED-00015733
Fibrosis-4 score and postoperative outcomes in metabolic dysfunction-associated steatotic liver disease
No full textBackground/Aims: The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) is increasing globally. The Fibrosis-4 (FIB-4) score is a noninvasive biomarker used for assessing potential advanced fibrosis. The study aimed to evaluate the role of the FIB-4 score in predicting postoperative complications and mortality in patients undergoing surgery. Materials and Methods: This multicenter retrospective study included 11 072 patients who underwent surgery under general anesthesia. Demographic and clinical data-including age, gender, comorbidities, FIB-4 scores, American Society of Anesthesiologists classification, postoperative complications, and mortality-were analyzed. Results: A total of 1667 MASLD patients were included. Patients were classified based on FIB-4 scores: 70% (n = 1167) had FIB-4 = 2.67. Due to the limited number of patients with possible advanced fibrosis (FIB-4 >= 2.67), propensity score (PS) matching was performed. After PS matching, patients with a high FIB-4 score exhibited a significantly higher rate of postoperative complications (P < .001), and 12-month mortality was elevated (11%), although the difference was not statistically significant (P = .481). Conclusion: A high FIB-4 score may serve as a predictive marker for postoperative complications in patients with MASLD undergoing surgery