Erciyes University - AVESIS
Not a member yet
96078 research outputs found
Sort by
Comparative analysis of milk casein hydrolysates from cow, water buffalo, goat and sheep: effects of flavourzyme and neutrase on formation of bioactive peptides
No full textThe casein hydrolysates of cow (CwC), water buffalo (WBuC), goat (GoC), and sheep (ShC) were obtained using neutrase (CwCN, BuCN, GoCN, and ShCN) and flavourzyme (CwCF, BuCF, GoCF, and ShCF). Untreated caseins and their respective enzyme (flavourzyme and neutrase) treated hydrolysates were compared in terms of selected bioactivities, free amino acids, and molecular weight distributions, etc. The enzymes displayed varied activities for 4 casein types. Flavourzyme was more aggressive than neutrase in the formation of peptides and free amino acids. The highest and the lowest degree of hydrolysis were determined for GoCF (166.8 mg tryptone /g casein) and ShCN (37.4 mg tryptone /g casein), respectively. Both enzymes significantly reduced the molecular weights of peptides in hydrolysates. The higher amounts of free amino acids were determined in flavourzyme treated caseins compared to neutrase treated ones; the highest was in ShCF (92.89 mg amino acid/g casein). The polypeptide ratio in ShC was 78.3%, but after treatment with flavourzyme and neutrase, the polypeptide ratio in hydrolysates were diminished to 23.5 and 25.3%, respectively, for ShCF and ShCN. The highest proportion of peptides in hydrolysates were oligopeptides (between 0.5 and 2.5 kDa), ranging from 67 to 76.7% for 8 enzyme treated caseins. FTIR spectra indicated modifications in caseins in amide I and II bands. Compared to their respective enzyme treated hydrolysates, the untreated caseins (CoC, WBuC, GoC, and ShC) displayed higher lipase inhibition activities (GoC having the highest inhibition, 66.34%). In the case of α-amylase inhibition, flavourzyme generated higher results for WBuCF (91.09%) and CwCF (86.96%) than their neutrase treated analogs. On the other hand, neutrase generated higher results for GoCN (67.3%) and ShCN (55.77%) than their flavourzyme treated analogs. Regarding ACE inhibition activity, GoCN and WBuCF displayed the highest results as 93.3% and 80.32%, respectively. The study demonstrated the promising potential of casein hydrolysates from different sources for the formulation of functional foods to combat chronic diseases including hyperglycemia, dyslipidemia, obesity, and hypertension
Activated Graphite@Nickel Oxide Nanoflowers for the Dispersive Solid-Phase Microextraction (DSPE) of Copper(II) from Water and Food
No full textActivated graphite@NiO nanoflowers was synthetized and characterized by field emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD) and Fourier transform infrared spectrometer (FTIR). It was used as adsorbent for dispersive solid-phase microextraction of Cu(II). The quantitative recovery values were found as pH 8.0, eluent 2.0 M HNO3, vortex time 30 s, adsorbent mass 20 mg, and preconcentration factor 80. The limits of detection and quantification were calculated as 4.23 µg L−1 and 14.1 µg L−1, respectively. The presented method was validated by the analyzing certified reference materials. It was sapplied to determination of copper contents of food and water samples
Characterization of genotypes in Türkiye mulberry genetic resources; antioxidant capacity, biochemical composition, nutrient content and morphological evaluation of leaves
No full textSimultaneous voltammetric determination of dopamine and uric acid using screen printed carbon electrode modified with quercetin functionalized-iron oxide nanoparticles
No full textDue to close oxidation potential values of dopamine (Dop) and uric acid (Uric), their simultaneous electrochemical detection in biological fliuds has always been a great problem of contineous research work. To address this issue magnetic iron oxide (Fe3O4) nanoparticles are promising eletrode materials owing to their high catalytic activity, easy synthesis procedure, lower cost and non toxic nature. Therefore, in the present work, we have investigated, a novel electrochemical sensor which is based on a screen printed carbon electrode (SPCE) modified with quercetin (Qr) functionalized-iron oxide nanoparticles (Qr-Fe3O4/SPCE) for the simultaneous voltammetric detection of Dop and Uric. The SEM analysis confirmed the porous morphology with nanosize distribution and XRD revealed the cystalline strucutre. The average size of the bare Fe3O4 and Qr-Fe3O4 nanoparticles were estimated to be 11.7 and 9.1 nm, respectively. The FT-IR analysis confirmed the successful functionalization of quercetin on the surface Fe3O4 nanoparticles. The cyclic voltammetric and electrochemical impedance spectroscopic techniques were used to characterize the electrical properties of the electrodes. The Qr-Fe3O4 sensor greatly improved the peak current signals towards the oxidation of Dop and Uric which was found to be due to the synergistic electrocatalytic effect of Qr and Fe3O4 nanoparticles on the electrode surface. The fabricated sensor presented linear peak current responses as a funtion of Dop and Uric concentrations in the ranges from 0.2 – 50 µM and 0.2 – 25 µM, with detection limits of 0.07 and 0.08 µM, respectively. Moreover, the Qr-Fe2O3/SPCE based sensor showed good repeatability with RSD of 1.7% for Dop and 2.8% for Uric and displayed good discrimination ability over the common interferents. The successful application of the sensor to the spike urine samples enabled the determinations with good recoveries without matrix effect from urine sample. Thus the developed electrochemical sensor could be a suitable sensing device for Dop and Uric with a large peak potential separation ability due to its easy preparation procedure, ecofriendly nature, lower cost and good sensitivity and selectivity
Türkiye-Afrika İlişkilerinin Savunma, Askeri ve Güvenlik Boyutunu Şekillendiren Dinamikler
No full textRespiratory surveillance and inward rectifier potassium channel expression in lung tissue within an experimental epilepsy model
No full textEpilepsy is characterized by neuronal discharges that occur as a result of disruption of the excitatory and inhibitory balance of the brain due to functional and structural changes. It has been shown in the literature that this neurological disorder may be related to the expression of ion channels. Any defect in the function or expression mechanism of these channels can lead to various neuronal disorders such as epilepsy. Epileptic seizures occur as a result of the accumulation of biological disorders in the circulatory, respiratory and nervous systems. In this study, we aimed to examine the changes in the expression of inward-directing potassium channels (Kir 3.1 and 6.2) in lung tissue and respiratory functions, considering that it will contribute to the elucidation of the mechanisms of sudden deaths thought to be caused by cardiorespiratory complications in epilepsy. In the study, 48 adult male Wistar albino rats weighing 250–300 g were used in the study. During the research process, respiratory function tests were performed on epileptic rats induced with pentylenetetrazol (PTZ) firing model, and then histopathological changes in lung and hippocampus tissues, and expression levels of the Kir (3.1 and 6.2) channels were evaluated by immunohistochemistry, qRT-PCR and Western blot analysis. Memantine and tertiapin-Q have been shown to protect epileptic groups from histopathological harm induced by PTZ application and also reduce HIF-1α, Kir 3.1 and Kir 6.2 expression. The findings imply that memantine and tertiapin-Q would be suitable options for treating epilepsy patients
The nexus between the financial development and CO2 emissions: Fresh evidence through time-frequency analyses
No full textInfections among adults hospitalized in intensive care after the 2023 earthquake in the southeastern part of Türkiye: a multi-center observational study.
No full textNOHUT BİTKİSİNDE YÜZEY ALTI DAMLA SULAMA SİSTEMİYLE FARKLI SULAMA REJİMLERİNİN BİTKİ SU KULLANIMINA, GELİŞİMİNE VE VERİMİNE ETKİSİ
No full textBu araştırmada Türkiye’nin İçAnadolu Bölgesi’nde suyu daha etkin kullanan yüzey altı damla sulama sistemiyleyetiştirilen Azkan çeşidi nohut bitkisinde (Cicerarietinum L.) farklı sulama rejimlerinin bitki su kullanımına, gelişimineve verimine etkileri incelenmiştir. Yüzey altı sulama sistemi altında nohutbitkisi tam sulama (%100), hafif su stresi (%75) ve orta su stresi (%50)etkisinde bırakılmıştır. Araştırma, Erciyes Üniversitesi Tarımsal Araştırma veUygulama Merkezi (ERÜTAM) Yıldırım Beyazıt deneme alanında 2023 vejetasyon döneminde yürütülmüştür.Tesadüf Blokları Deneme desenine göre kurulan çalışmada her konu 3 keztekrarlanmıştır. En düşük ve en yüksek sulama suyu miktarları 136.6 (YAD50)- 273.2 (YAD100) mm ve mevsimlik bitki su tüketimleri ise 262.1-378.8 mm arasında değişmiştir. Su kullanım etkinliği 0.79-1.00 kg/m3ve sulama suyu kullanım etkinliği 1.51-1.42 kg/m3 aralığındabelirlenmiştir. Yapılan çalışmada İç Anadolu Bölgesi’nde yüzey altı damlasulama ile yetiştirilen nohudun Ky değeri 1.57 olarak saptanmıştır. Tane verimisulama suyu seviyesine bağlı olarak 2060 (YAD50) - 3870 (YAD100)kg/ha arasında değişmiştir. Sonuç olarak; Kayseri ekolojik koşullarındayüzey altı damla sulama sistemiyle sulanan nohut bitkisinden yüksek verim eldeedilebilmesi için tam sulama yapılması önerilmiştir.</p