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Full mouth rehabilitation with fixed prostheses in the case of unaligned and malpositioned implants: clinical report
Get PDFFull mouth rehabilitation with fixed implant supported prostheses is one of the challenging treatments, because important factors in aesthetic and function should be considered. Implants' alignments and locations should be planned before the insertion unless the improper inclination and location of implants would lead to difficulties in patient's comfort, oral hygiene problem and inability to reconstruct the acceptable functional and aesthetical prosthesis.
This clinical report described the step by step prosthetic treatment procedure of full mouth rehabilitation and 1-year follow-up of a patient who underwent 10 and 8 implants in upper and lower jaw respectively, which were unaligned and malpositioned. In the cases of improper alignment and position of implants, modified prosthetic design with consideration of biomechanical principles should be incorporated to overcome the limitations
Evaluation of seroprevalence and seroconversion rates of Toxoplasma gondii infection in female students at Babol University of Medical Sciences, Babol, Iran
Get PDFObjectives: The primary infection of pregnant women by Toxoplasma gondii can cause severe complications in the fetus, and can also lead to neurological complications. The aim of the present study was to determine the seroprevalence and seroconversion rates of Toxoplasma gondii in female students who were at childbearing age in Iran.
Methods: This cross sectional study was performed on female students at Babol University of Medical Sciences (Babol, Iran) over a three-year period between 2012 and 2014. Two ml blood sample was obtained from volunteers, and the specific antibodies (IgG) to T. gondii were detected by Enzyme-Linked Immunosorbent Assay. Second, the blood samples obtained from seronegative cases were used to evaluate the seroconversion during a year.
Results: The mean age of the subjects was 21±2.2, ranging from18 to 35 years. Overall, 28% of the participants were positive and 232 (72%) were negative for anti-Toxoplasma antibodies (IgG). The rate of this infection was higher among female students from Mazandaran province (31.7% vs 12.5%) (P=0.031). Based on the results of Enzyme-Linked Immunosorbent Assay, the seroconversion rate of Toxoplasma infection among female students was estimated to be 2.5%.
Conclusion: This study found a noticeable rate of seroconversion in female students. Therefore, there is an urgent need for a national screening project to determine the seroconversion rate of Toxoplasma infection in women at childbearing age, particularly pregnant women from all over Iran
Assessing prevalence and clinical characteristics of polycystic ovary syndrome in young adults, Iran
Get PDFBackground: Studies have revealed that Polycystic Ovary Syndrome (PCOS) usually begins in adolescence and it might manifest differently in different populations. The aim of this study was to estimate prevalence and clinical characteristics of PCOS in a community setting in Iran.
Methods: In a community-based cross-sectional study 401 young women aged 18-33 years selected by cluster sampling proportionate to population size. An interviewer-administered questionnaire was used to screen predisposing factors for PCOS based on menstrual history and clinical manifestations of hyperandrogenism. PCOS be defined presence of least two criteria were considered diagnostic of PCOS, after exclusion of other etiologies.
Results: The overall prevalence of PCOS among young women was 19.0% (CI 95%; 15.0%, 23%). Compared with non-PCOS young women, The adjusted age OR of young women PCOS for problem in abnormal hair growth 5.07 (CI, 2.87-8.99; P< 0.0001) weight loss 4.72 (CI, 2.75-8.09; P< 0.0001), abdominal obesity was 1.83 (95% CI, 1.00 -3.11; p= 0.026), paternal alopecia was 1.760 (CI 95%, 1.03-3.02; p = 0.040), and consume pill for menstruation 18.75 (CI 95%, 6.53-53.96; p< 0.0001). There were no significant difference between acne, increased weight, and depression with PCOS. The women with regular cycles in the absence of clinical hyperandrogenism 98.9% were confirmed as normal. While 93.9 % women with irregular cycle and clinical hyperandrogenism were confirmed to have PCOS.
Conclusions: The results of this study indicated that counseling and evaluating of the women with irregular cycle and clinical hyperandrogenism using an interviewer-administered questionnaire may be benefit for diagnosis of PCOS
Nifedipin versus magnesium sulfate for suppression of preterm labor: A randomized Clinical trial
Get PDFBackground: Preterm labor is a leading cause of fetal and neonatal morbidity and mortality. There are various kinds of drugs used to suppress the preterm labor, but they are not thoroughly effective. The aim of this study was to compare the effectiveness of oral nifedipine with intravenous magnesium sulfate in delaying the preterm labor.
Methods: A randomized, clinical trial was conducted in a hospital in Babol, Iran. One hundred twenty singleton pregnant women with preterm labor, 24-37 weeks of gestation, were randomly assigned to receive oral nifedipine or intravenous magnesium sulfate. The main outcome of the study was the inhibition of uterine and the secondary outcome was the side effect related to drugs and neonatal outcome. The data were analyzed with SPSS software, using chi-squared test and independent t test.
Results: According to the results, in 35% of women in the nifedipine group and 23.3% of women in the magnesium sulfate group, the inhibited uterine contraction was less than 48 hours. Also, in 65.0% of women in the nifedipine group and 76.7% of women in the magnesium sulfate group, the inhibited uterine contraction was more than 48 hours. There was no significant difference between the nifedipine and the magnesium sulfate groups in the inhibition of uterine contraction in both less and more than 48 hours. The total side effects of medication were found to be lower in patients receiving oral nifedipine than those who received intravenous magnesium sulfate. (26.6 vs. 45.0) (p= 0.036). There was no significant difference in neonatal outcome between the two groups.
Conclusion: Oral nifedipine should be a suitable alternative to intravenous magnesium sulfate in suppression preterm labor with fewer side effects
Assessment of micro-leakage for light-cure glass ionomer and pro-root mineral trioxide aggregate as coronal barriers in intracoronal bleaching of endodontically treated teeth
Get PDFIntroduction: Cervical root resorption is one of the most important complications of intra coronal bleaching. A way of preventing this type of resorption is using a coronal barrier under the bleaching materials. The aim of this study was to compare the sealing ability of glass ionomer cement and Pro Root Mineral Trioxide Aggregate (MTA) as a coronal barrier in intra coronal bleaching.
Materials &Methods: In this study, 40 single-root maxillary anterior teeth were endodontically prepared and divided into two experimental groups (n= 15) and two positive and negative control groups (n=5). In the experimental groups, gutta percha was removed up to 3 mm below the cemento enamel junction (CEJ).RMGI and MTA were placed over gutta percha up to the level of CEJ. After a 24-hour incubation period, the bleaching agent (a mixture of sodium perborate and 30% hydrogen peroxide) was placed in the access cavities. The bleaching agents were replaced every 3 days over 9 days. Then, the access cavity was filled with 2% methylene blue for 48 hours. All samples were longitudinally sectioned and the dye penetration range was evaluated using a stereomicroscope. Data were statistically analyzed using Kruskal-Wallis and Mann–Whitney tests (α=0.05).
Results: Leakage mean indicated that there was a significant difference between these two groups and leakage was less in ProRoot than glass ionomer.
Conclusion: It seems that the MTA can provide a better coronal seal during the bleaching
Psychometric feature of the child and parent versions of psychological inflexibility in pain scale (PIPS) in children with chronic pain and their parents
Get PDFBackground: The aim of this study was to investigate the validity, reliability and factor structure of the child and parent's version of psychological inflexibility in pain scale (PIPS) in the population of children with chronic pain and their parents.
Methods: The sample consisted of 112 pairs of children and parents, selected through available sampling method from the Tehran Children's Hospitals. The PIPS questionnaire along with KIDScreen scale (to measure well-being), Child Behavior Checklist (CBCL) (the Youth Self-Report (YSR)) (to measure negative mood) and Visual Analogous Scale (VAS) (to measure pain severity) was implemented on them.
Results: The reliability results of PIPS showed that the Cronbach's alpha for the child and parent versions was 0.66 and 0.82, respectively. In addition, the rerun correlation of child and parent versions was significant and acceptable, ranging from 0.47 to 0.78. Moreover, the highest correlation between PIPS dimensions in two versions of the child and parent was 0.89 and 0.92, respectively. The convergent and divergent validity of the PIPS showed that this questionnaire had a negative and significant correlation with the KID Screen scale and had a positive and significant correlation with the CBCL, YSR and VAS.
Conclusions: The results of the exploratory factor analysis of this questionnaire revealed new factors. The exploratory factor analysis of child version indicated four factors (the factors 1, 3 and 4 are related to avoidance, and factor 2 measures the fusion) and in the confirmation factor analysis, the good fitting of these new factors was confirmed
Factors influencing the ovarian response in intracytoplasmic sperm injection (ICSI)
Get PDFBackground: Ovarian response to gonadotropin stimulation can predict the success rate of Assisted Reproductive Technology. The purpose of this study was not only to determine the ovarian response rate in patients on whom intracytoplasmic sperm injection (ICSI) did not successfully work but also to assess the influence of factors on ovarian response.
Methods: In a retrospective study, the medical records of 220 women undergoing their first cycle of ICSI from March 2012 to October 2016 were thoroughly examined. Special attention was paid to ovarian response with regards to age, body mass index, the history of menstrual cycle, the type of infertility, the duration of infertility, and the cause of infertility with respect to measures of women’s hormones. The ovarian response expressing the number of mature MII oocytes after oocyte retrieval was regarded as “poor response” representing a yield of 1–4 oocytes, and “appropriate response” representing a yield of 5 or more oocytes.
Results: Out of 220 infertile women, 45 subjects (20.5%) had poor response, 175 subjects (79.5%) had appropriate response to ovulation stimulation with gonadotropin. The results of indicated that lower female age (p=0.005) and lower female FSH (p=0.006) were consistent with appropriate ovarian response. After adjusting the variables, the age (age <30 years) (OR= 2.45, 95% CI= 1.19-5.07) and the female FSH (FSH <30 years) (OR= 2.59, 95% CI= 1.16-5.71) were found to be associated with an appropriate ovarian response.
Conclusion: It can be concluded that entering the first cycle of ICSI with FSH test and considering the age of women seem to be acceptable strategies
The ENPP1 K121Q polymorphism modulates developing of bone disorders in type 2 diabetes: A cross sectional study
No full textBackground: Osteoporosis and osteopenia are common diseases in every population. Type 2 diabetes mellitus (T2DM) can lead to the development of various complications, such as bone disorders especially among elderly individuals. Studies suggested that ectonucleotide pyrophosphatase/phosphodiesterasel (ENPP1) is contributed in insulin resistance and also the inhibition of bone mineralization. In this study, association of K121Q (rs1044498) polymorphism of the ENPP1 gene with T2DM and bone disorders is evaluated. Methods: Four-hundred-and-ninety females who were classified based on bone mineral density (BMD) at lumbar spine and femur were included in this study. In addition, participants were classified according to their diabetes status. K121Q polymorphism was evaluated by the PCR-PFLF technique. One-way ANOVA was used for comparison of various analyzed factors in diseases subgroups and K121Q genotypes. Association of K121Q polymorphism with diabetes and bone disorders was evaluated by logistic regression. Results: Significant association was observed between K121Q polymorphism with osteoporosis and osteopenia (p = 0.041, p = 0.029, respectively), but a similar pattern was not observed in T2DM status (p = 0.723). Moreover, in diabetic patients, K121Q polymorphism showed a better prediction potential for the development of bone disorders in comparison to non-diabetic subjects (p = 0.018; OR = 4.63,p = 0.540; OR = 1.31). There were no significant differences between K121Q genotypes with FBS, Ca, P, vitamin D, PTH and BMD status. Conclusions: The present study implies that K121Q polymorphism of ENPP1 gene is able to modulate the development of bone disorders in T2DM. Therefore in diabetic patients screening of this polymorphism is suggested for the monitoring of these persons
Evaluation of scientific outputs of Kashan University in Scopus Citation Database 2012-2016
Get PDFBackground and aim: Scientometrics is a modern field of library and information science, which is used to measure the sciences quantitatively at national and international levels in order to rank the publications, universities and countries. The aim of this study was to determine the scientific outputs of faculty members in Kashan University as a sample of Iranian universities from 2012 to 2016.
Material and methods: Data were collected from Scopus through scientometric method. Scientific outputs of faculty members in Kashan University were evaluated from 2012 to 2016. Data were analyzed using Excel and SPSS 20 via ANOVA and T-student tests.
Findings: Results showed that the highest number of scientific outputs was original articles (89.3%) of which 85.49% were written by male researchers. Faculty members with degree of professor had the highest number of scientific outputs (41.2%). There was no significant relationship among different educational groups in terms of scientific outputs (P=0.31). Faculty members of the basic sciences (59.55%) and engineering (36.59%) had the highest scientific outputs, respectively.
Conclusion: The results indicated that scientific outputs of this University have been had ascending trend during recent five years, which is an effective factor in improving and promoting the scientific status of Kashan University among national and international universities
Citation Analysis of the References of the PhD Theses in Knowledge and Information Science at Ahwaz Shahid Chamran University
Get PDFBackground and aim: Citation analysis is one of the important ways to assess the status of utilizing references used by students in writing dissertations. The aim of this research was to study the status of references used in PhD theses of Knowledge and Information Science at Ahwaz Chamran University (2009-2015).
Material and methods: The citation analysis method was used in this study, and the population was 3048 citations extracted from the references of 20 PhD dissertations at Ahwaz Shahid Chamran University. Data were analyzed using Excel.
Findings: Findings showed that periodicals with 1696 citations (55.64%) had the highest rate of citation and the citation mean was 152.4 for each thesis. In addition, Latin resources were more cited than Persian resources. English language with 2050 (67.26%) citations had the highest rate of citations. The Persian and Latin references had only one author. The most cited authors, resources and half –life resources were identified. Citing scientific productions of supervisors and advisors were very low so that out of 3048 citations, only 180 (5.90%) citations were referred to the scientific productions of supervisors and advisors.
Conclusion: In writing the dissertations, Latin resources were mostly used. The highly cited resources and authors can be employed in the selection of library resources, and regarding half-life as a criterion for evaluating the novelty of resources, it is concluded that new resources are not used in writing the theses by PhD students