HAL UVSQ
Not a member yet
57319 research outputs found
Sort by
Sea Surface Wave Remote Sensing
No full textInternational audienceAs a type of gravity wave travels at the interface between atmosphere and ocean, sea surface wave is a fundamental dynamic phenomenon which must be considered in oceanographic research, offshore engineering and maritime shipping etc. With the rapid development of space science and technology, satellite remote sensing has become an indispensable technology to observe and understand sea surface waves due to its advantages of global coverage, all-weather and all-day characteristics. This chapter introduces the characterization methods and main parameters of sea surface waves, the main spaceborne microwave payloads and observation principles of sea surface waves, and the main scientific and operational applications of satellite surface wave data
Aetheras: Characterising exoplanetary atmospheric escape with NIR and UV spectroscopy
No full textInternational audienceTo date, many exoplanets have been discovered which exhibit distinct characteristics not observed within our own Solar System, raising numerous unresolved questions regarding their compositions, atmospheres, formation processes, and evolutionary pathways.Several missions have been dedicated to enhance the understanding of the exoplanets like James Webb and Hubble Space Telescopes. However, they have a limited spectral range and resolution to allow for a complete characterisation of atmospheric dynamics. The Aetheras mission proposal was developed at the Summer School Alpbach 2023 and presents a satellite mission to overcome these limitations to better understand the formation, evolution and characteristics of exoplanets. This mission aims to unravel key enigmas in contemporary</p
Unveiling distinct neuroimmune responses in mouse models of cervical spinal cord injury: Hemisection versus hemicontusion
No full textInternational audienc
Tissue from gender-affirming genital surgery as a model for human penile physiology research: promise, ethics, and scientific duty. A gift from transgender women to the science of male sexuality
No full textInternational audienc
Perinatal outcomes following <i>in‐utero</i> transfusion for hydrops fetalis associated with parvovirus <scp>B19</scp> infection
No full textInternational audienceABSTRACT Objective Congenital parvovirus B19 (PB19) infection can lead to severe fetal anemia and hydrops fetalis, necessitating in‐utero transfusion (IUT) as a life‐saving intervention. This study aimed to identify risk factors associated with unfavorable perinatal outcome following IUT in hydropic fetuses with PB19 infection, with the goal of optimizing transfusion strategies and improving fetal survival. Methods A retrospective, multicenter, international cohort study was conducted across nine specialized fetal medicine centers in France, Belgium and the Czech Republic. This study included pregnant women with a fetus diagnosed with hydrops due to PB19 infection that underwent at least one IUT for severe fetal anemia between January 2014 and May 2024. Clinical, demographic and procedural data were analyzed. The primary outcome was to identify maternal, fetal, obstetric or IUT‐related risk factors associated with adverse fetal or neonatal outcome, defined by a composite criterion of unfavorable outcome that included perinatal mortality and/or severe and persistent fetal anomalies, including severe fetal brain injury at follow‐up. Statistical analysis was conducted using logistic regression models to assess potential risk factors. Results Of the 84 eligible cases, 78 pregnancies were included in the final analysis. The rate of perinatal survival without severe brain injury was 59.0% (46/78), while 41.0% (32/78) of cases had an unfavorable outcome, including 20 (25.6%) cases of stillbirth, nine (11.5%) cases of termination of pregnancy, one (1.3%) case of continuation of pregnancy despite severe prenatal neurological findings and two (2.6%) cases of neonatal death. Notably, a higher fetal hemoglobin (Hb) level (> 9.3 g/dL) after the first or second IUT was significantly associated with a reduced risk of unfavorable outcome (adjusted odds ratio (aOR), 0.6 (95% CI, 0.4–0.8)). A femur length Z‐score of < −2 was associated with unfavorable outcome (aOR, 5.4 (95% CI, 1.3–27.0)). Transplacental vs transamniotic funicular puncture was not significantly associated with perinatal survival. Conclusions IUT remains a cornerstone intervention for managing severe fetal anemia caused by PB19 infection; however, rates of perinatal loss continue to be substantial, especially in the presence of severe hydrops. Achieving higher post‐transfusion Hb levels appears to be an important factor in improving survival outcomes for hydropic fetuses with PB19 infection. © 2026 International Society of Ultrasound in Obstetrics and Gynecology
Migraine, associated treatments and risk of miscarriage: A matched cohort study and nested case-control study using the CPRD pregnancy register
No full textInternational audienceObjective To estimate the risk of miscarriage amongst pregnant women with migraine compared to pregnant women without migraine. To compare the odds of miscarriage in women taking medication for migraine to women with migraine who did not take medication and to explore this association with different types of medications. Design Matched cohort study and nested case-control. Setting Clinical Practice Research Datalink (CPRD) GOLD pregnancy register. All pregnancies meeting data quality requirements between 2000 and 2019 were eligible for inclusion. Participants Cohort study: 193,208 pregnancies of women with migraine were matched one-to-one to women without migraine. Nested case-control: 20,778 pregnancies of women with migraine that ended in miscarriage were matched to 40,122 pregnancies of women with migraine that did not end in miscarriage. Main outcome measures Cohort study: miscarriage recorded in primary care. Nested case-control: odds of miscarriage amongst migraineurs using migraine medication. Results Miscarriage occurred in 10% (n = 19,233) of women without migraine compared to 10.8% (n = 20,778) of women with migraine. Having migraine was associated with an 8% higher relative risk of miscarriage (risk ratio (RR) 1.08, 95% confidence interval (CI) 1.06–1.10, p < 0.001) and remained significant after adjustment for demographic factors, body mass index (BMI), smoking and comorbidities (aRR 1.06 95% CI [1.04–1.08][p = 0.001]). Of the pregnancies ending in miscarriage, 719 (3.46%), 380 (1.83%), 173 (0.83%) and 733 (3.52%) were exposed to triptans, amitriptyline, beta-blockers and non-steroidal anti-inflammatory drugs (NSAIDs), respectively. Of the matched pregnancies that did not end in miscarriage, 1099 (2.74%), 542 (1.35%), 294 (0.73%) and 780 (1.94%) were exposed to these medications, respectively. Exposure to triptans, amitriptyline and NSAIDs were associated with a significantly higher odds of miscarriage (aORs 1.24 [1.11–1.38][p < 0.001], 1.25 [1.08–1.45][p = 0.003] and 1.74 [1.57–1.93][p < 0.001] respectively). Beta-blockers were not associated with a higher risk of miscarriage. Conclusions Migraine and triptan, amitriptyline and NSAID exposure were all associated with higher risk of miscarriage. Further work is needed to understand the potential causative mechanisms
Generic Attacks on Classical Feistel Ciphers with Internal Permutations
No full textInternational audienc
Does the susceptibility vessel sign influence the effectiveness of intravenous thrombolysis before endovascular thrombectomy in acute ischaemic stroke?
No full textInternational audienceAbstract Introduction The benefit of intravenous thrombolysis (IVT) prior to EVT in acute ischaemic stroke (AIS) remains debated. We evaluated the association of the susceptibility vessel sign (SVS) with clinical and angiographic outcomes and assessed whether its presence modified the effect of IVT. Patients and methods We retrospectively analysed patients with anterior circulation large vessel occlusion from the multicentre ETIS registry who underwent EVT. Susceptibility vessel sign presence and extent were assessed on MRI and categorised as binary (SVS− vs SVS+) and 3-class (SVS−, SVS+, SVS++) variables. Multivariable regression was used to evaluate associations and interactions between SVS and IVT for the primary (90-day mRS 0–2) and secondary (90-day ordinal mRS and mortality, first-pass expanded thrombolysis in cerebral infarction [eTICI] 2c-3 and final eTICI 2b-3) outcomes. Results Among the 1250 patients analysed, 909 were included. Susceptibility vessel sign was present in 84.5% of patients and associated with improved 90-day mRS 0–2: adjusted odds ratio (aOR) 2.03; 95% CI, 1.18–3.46. No interaction between SVS and IVT was observed for clinical outcomes. However, SVS modified the effect of IVT on final TICI 2b-3 (Pinteraction = .03): IVT + EVT was associated with higher odds of successful reperfusion in SVS+ patients (aOR 2.00; 95% CI, 1.28–3.52) but not in SVS− patients (aOR 0.60; 95% CI, 0.16–1.97). In a secondary analysis using 3-class SVS, only SVS++ (larger hyposignal) was significantly associated with better outcomes and showed interaction with IVT for final eTICI 2b-3. Conclusion Susceptibility vessel sign, particularly SVS++, was associated with improved clinical outcomes and enhanced the effect of IVT on reperfusion success in EVT-treated AIS
