The Egyptian Cardiothoracic Surgeon (ECTS - E-Journal)
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Using Silent Substitution to Track the Mesopic Transition. From Rod- to Cone-Based Vision in Mice
No full textCombination of searches for WW, WZ, and ZZ resonances in pppp collisions at s√=8s=8 TeV with the ATLAS detector
No full textThe ATLAS experiment at the CERN Large Hadron Collider has performed searches for new, heavy bosons decaying to WW, WZ and ZZ final states in multiple decay channels using 20.3 fb−1 of pp collision data at s=8 TeV. In the current study, the results of these searches are combined to provide a more stringent test of models predicting heavy resonances with couplings to vector bosons. Direct searches for a charged diboson resonance decaying to WZ in the ℓνℓ′ℓ′ (ℓ=μ,e), ℓℓqq¯, ℓνqq¯ and fully hadronic final states are combined and upper limits on the rate of production times branching ratio to the WZ bosons are compared with predictions of an extended gauge model with a heavy W′ boson. In addition, direct searches for a neutral diboson resonance decaying to WW and ZZ in the ℓℓqq¯, ℓνqq¯, and fully hadronic final states are combined and upper limits on the rate of production times branching ratio to the WW and ZZ bosons are compared with predictions for a heavy, spin-2 graviton in an extended Randall–Sundrum model where the Standard Model fields are allowed to propagate in the bulk of the extra dimension
Re-conceiving building design quality: a review of building users in their social context
No full textConsiderable overlap exists between post-occupancy research evaluating building design quality and the concept of ‘social value’, popularised by its recent application to issues of the public realm. To outline this potential research agenda, the paper reviews design quality research on buildings in relation to users and their social context where the term ‘social context’ refers to building user group dynamics, a combination of organisational cultures, management strategies, and social norms and practices. The review is conducted across five key building types, namely housing, workplaces, healthcare, education, and the retail/service sector. Research commonalities and gaps are identified in order to build a more comprehensive picture of the design quality literature and its handling of users in their social context. The key findings concerning each building type are presented visually. It is concluded that the design quality field comprises a patchwork of relatively isolated studies of various building types, with significant potential for theoretical and empirical development through interdisciplinary collaboration. Users tend to be conceived as anonymous and autonomous individuals with little analysis of user identity or interaction. Further, the contextual impact of user group dynamics on the relationship between building design and building user is rarely addressed in the literature. Producing a more nuanced understanding of users in situ is proposed as an important area for future design quality research
Citizen Media and Public Spaces:Diverse Expressions of Citizenship and Dissent
No full textCitizen Media and Public Spaces presents a pioneering exploration of citizen media as a highly interdisciplinary domain that raises vital political, social and ethical issues relating to conceptions of citizenship and state boundaries, the construction of publics and social imaginaries, processes of co-optation and reverse co-optation, power and resistance, the ethics of witnessing and solidarity, and novel responses to the democratic deficit. Framed by a substantial introduction by the editors, the twelve contributions to the volume interrogate the concept of citizen media theoretically and empirically, and offer detailed case studies that extend from the UK to Russia and Bulgaria and from China to Denmark and the liminal spaces within which a growing number of refugees now live. A rich new domain of scholarship and practice emerges out of the studies presented. Citizen media is shown to embrace both physical and digital interventions in public space, as well as the sets of values and agendas that influence and drive the practices and discourses through which individuals and collectives position themselves within and in relation to society and participate in the creation of diverse publics
Effect of QW growth temperature on the optical properties of blue and green InGaN/GaN QW structures
No full textIn this paper we report on the impact that the quantum well growth temperature has on the internal quantum efficiency and carrier recombination dynamics of two sets of InGaN/GaN multiple quantum well samples, designed to emit at 460 and 530 nm, in which the indium content of the quantum wells within each sample set was maintained. Measurements of the internal quantum efficiency of each sample set showed a systematic variation, with quantum wells grown at a higher temperature exhibiting higher internal quantum efficiency and this variation was preserved at all excitation power densities. By investigating the carrier dynamics at both 10 K and 300 K we were able to attribute this change in internal quantum efficiency to a decrease in the non-radiative recombination rate as the QW growth temperature was increased which we attribute to a decrease in incorporation of the point defects. (© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
A mechanistic multicentre, parallel group, randomised placebo-controlled trial of mesalazine for the treatment of IBS with diarrhoea (IBS-D).
No full textINTRODUCTION: Immune activation has been reported in the mucosa of IBS patients with diarrhoea (IBS-D), and some small studies have suggested that mesalazine may reduce symptoms. We performed a double-blind, randomised placebo-controlled trial of 2 g mesalazine twice daily versus placebo for 3 months in patients with Rome III criteria IBS-D. Primary outcome was daily average stool frequency during weeks 11-12; secondary outcomes were abdominal pain, stool consistency, urgency and satisfactory relief of IBS symptoms. METHODS: Participants were randomised after a 2-week baseline stool diary. All participants completed a 12-week stool diary and at the end of each week recorded the presence of 'satisfactory relief of IBS symptoms'. RESULTS: 136 patients with IBS-D (82 women, 54 men) were randomised, 10 patients withdrew from each group. Analysis by intention to treat showed the daily average stool frequency during weeks 11 and 12 were mean (SD), 2.8 (1.2) in mesalazine and 2.7 (1.9) in the placebo group with no significant group difference, (95% CI) 0.1 (-0.33 to 0.53), p=0.66. Mesalazine did not improve abdominal pain, stool consistency nor percentage with satisfactory relief compared with placebo during the last two-weeks follow-up. CONCLUSIONS: This study does not support any clinically meaningful benefit or harm of mesalazine compared with placebo in unselected patients with IBS-D. More precise subtyping based on underlying disease mechanisms is needed to allow more effective targeting of treatment in IBS. TRIAL REGISTRATION NUMBER: NCT01316718
Feline Politics: The Nine Lives of Olly the Cat
No full textThe appearance of ‘Olly the cat’ on the doorsteps of a major UK international airport provides occasion to reconsider the role of the animal in organization and provides suggestive insight into how we might have to learn new ways of being within extended multi-species or inter-species ontologies. Olly is found to lead multiple lives that cannot be reduced to the status of object or media of human intentionality. Her increasing political involvement in the management and organization of the airport challenges orthodox understanding of agency and organizational action as the ethnography becomes progressively more implicated in the complex entanglements between human and animal. The concept of ‘feline politics’ is proposed and deployed in order to retain focus on actions and behaviour and modes of thinking that would ordinarily be occluded by dualistic modes of analysis. With this conceptual resource and newfound sensibility the ethnography moves beyond the interpretative and symbolic treatment of organization analysis and finds resource in the recent ‘ontological turn’ in the social sciences. Embracing what is the inevitable participation of the social sciences in the reflexive and recursive enactment of its phenomena the ethnography discovers new potentialities and new capacities for action as emergent properties of ‘the human’ and ‘the animal’ were mutually learnt, exchanged and acquired through feline politics. The paper adds to what we know about the limits of management as it confronts a radical undecidability characterised by the co-existence of multiple and interacting ontologies in organization
Calcinosis preferentially affects the thumb compared to other fingers in patients with systemic sclerosis.
No full textOBJECTIVES: Although Raynaud's phenomenon often spares the thumb, clinical experience suggests conversely that, in patients with systemic sclerosis (SSc), the thumb is frequently affected by calcinosis (as is demonstrated on plain radiographs). Our aim was to investigate the hypothesis that, in patients with SSc, thumbs are more commonly affected by calcinosis than other digits. METHOD: Sixty-eight hand radiographs with at least one area of calcinosis were identified. Each digit on both hands of each patient was assigned a severity score on a scale from 0 to 3 (0 = no calcinosis, 3 = most severe). The scoring was completed twice, including and excluding the metacarpals. RESULTS: Right hands were found to be associated with slightly higher scores than left hands [estimate 0.14, 95% confidence interval (CI) 0.03-0.26]. Scores were lower for other fingers compared to thumbs. There was strong evidence (p <0.0001) of a trend of decreasing severity moving from the thumb to the little finger. There was no evidence that the pattern of severity across the fingers was different on left and right hands (p = 0.77). The results were similar whether or not metacarpals were included. CONCLUSIONS: The thumb is affected by calcinosis more than other digits, followed by the index finger. This observation provides insight into the pathogenesis of SSc-related calcinosis, which may relate more to repetitive trauma than to ischaemia