The Egyptian Cardiothoracic Surgeon (ECTS - E-Journal)
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The New International Division of Labour and the Differentiated Integration of Europe:The Case of Spain
No full textThe chapter argues that it is of crucial importance to understand the longer-term historical role played within the new international division of labour (NIDL) by relatively late industrialising countries that are today bearing the brunt of crisis and ‘internal devaluation’ in a ‘unified’ Europe. Focusing on Spain, they argue that it is precisely on the material basis of its full integration within the NIDL from the mid-1970s that the conditions of the reproduction of the working class were re-shaped, and it is this ‘historical component’ in the reproduction of the Spanish accumulation process that has prefigured the process of the differentiation of the conditions of the reproduction of the working class within and across its borders ever since
Environmental and Social Disclosures: Link with Corporate Financial Performance
No full textEnvironmental and social disclosures entail costs, yet increasingly, large listed firms are making higher and better quality disclosures. In this paper we examine the link between a firm's environmental and social disclosures and its profitability and market value. We find that past profitability drives current social disclosures. However, consistent with the existing evidence, we do not find any relation between environmental disclosures and profitability. Further, while prior literature has largely focussed on environmental disclosure, we find that it is the social disclosures that matter to investors. We find that firms that make higher social disclosures have higher market values. Further analysis reveals that this link is driven by higher expected growth rates in the cash flows of such companies. Overall our findings are consistent with the resource based view of the firm and the voluntary disclosure theory, suggesting that firms with greater economic resources make more extensive disclosures which yield net positive economic benefits
Is pelvic vein incompetence associated with symptoms of chronic pelvic pain in women? A pilot study
No full textThe anisotropic growth morphology and microstructure of plutonium hydride reaction sites
No full textAssociation of Toll-like receptor 4 (TLR4) with chronic plaque type psoriasis and psoriatic arthritis
No full textFamily studies have provided overwhelming evidence for an underlying genetic component to psoriasis. Toll-like receptors (TLRs) are key transmembrane proteins in both the innate and adaptive immune responses which are known to be integral processes in psoriasis. Recent functional studies support this notion having suggested a role for TLR4 in the pathogenesis of psoriasis. Furthermore a missense polymorphism in the TLR4 gene has been associated with a number of autoimmune conditions, including Crohn diseases, making TLR4 a viable candidate gene for investigation. The aim of this study was to investigate polymorphisms across the TLR4 region with a high-density single nucleotide polymorphism (SNP) panel in a large cohort of patients with chronic plaque type psoriasis. Twenty SNPs were successfully genotyped using Sequenom iPLEX Gold platform in 2826 UK chronic plaque type psoriasis patients including subgroup data on presence of confirmed psoriatic arthritis (n = 1839) and early-onset psoriasis (n = 1466) was available. Allele frequencies for psoriasis patients were compared against imputed Wellcome Trust Case Control Consortium controls (n = 4861). Significant association was observed between a missense variant rs4986790 of TLR4 (Asp229Gly) and plaque type psoriasis (p = 2 × 10(-4)) which was also notable in those with psoriatic arthritis (p = 2 × 10(-4)) and early-onset psoriasis (p = 8 × 10(-4)). We present data suggestive of an association between a functional variant and an intronic variant of TLR4 and chronic plaque type psoriasis and psoriatic arthritis. However, validation of this association in independent cohorts will be necessary
Guidelines for reporting embedded recruitment trials
No full textBackgroundRecruitment to clinical trials is difficult with many trials failing to recruit to target and within time. Embedding trials of recruitment interventions within host trials may provide a successful way to improve this. There are no guidelines for reporting such embedded methodology trials. As part of the Medical Research Council funded Systematic Techniques for Assisting Recruitment to Trials (MRC START) programme designed to test interventions to improve recruitment to trials, we developed guidelines for reporting embedded trials.MethodsWe followed a three-phase guideline development process: (1) pre-meeting literature review to generate items for the reporting guidelines; (2) face-to-face consensus meetings to draft the reporting guidelines; and (3) post-meeting feedback review, and pilot testing, followed by finalisation of the reporting guidelines.ResultsWe developed a reporting checklist based on the Consolidated Standards for Reporting Trials (CONSORT) statement 2010. Embedded trials evaluating recruitment interventions should follow the CONSORT statement 2010 and report all items listed as essential. We used a number of examples to illustrate key issues that arise in embedded trials and how best to report them, including (a) how to deal with description of the host trial; (b) the importance of describing items that may differ in the host and embedded trials (such as the setting and the eligible population); and (c) the importance of identifying clearly the point at which the recruitment interventions were embedded in the host trial.ConclusionsImplementation of these guidelines will improve the quality of reports of embedded recruitment trials while advancing the science, design and conduct of embedded trials as a whole.<br/
Inter- versus Intramolecular Structural Manipulation of a Dichromium(II) Pacman Complex through Pressure Variation
No full textAssessment of the Thermal Conductivity of Intumescent Coatings in Fire
No full textThis paper presents an analytical method to calculate the expansion of intumescent coatings under different heating and fire conditions, being the most critical step in quantifying their fire protection performance under different conditions. The proposed method extends that of Amon and Denson, originally developed for spherical bubbles in viscous fluid subject to increase in pressure within the bubbles, to intumescent coatings with non-uniform temperature field and temperature-dependent viscosity. The pressure increase inside the bubbles is a result of the conversion of intumescent coatings from melt to gases at high temperatures. The extended analytical method has been used to predict the expansion processes of intumescent coatings tested by Zhang et al under cone calorimeter with different heating rates and under furnace fire condition with different temperature-time curves, and those of Muller under cone calorimeter heating. In these tests, intumescent coatings were applied to steel plates and the tests examined the effects of different coating thicknesses and steel plate thicknesses, therefore allowing the fire and cone calorimeter tests to encompass a wide range of temperatures and rates of heating. Comparison of the analytical calculation and test results indicates that the proposed method is suitable for quantifying the expansion process of intumescent coatings