3872 research outputs found
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URROC- Undergraduate Research in Organic Chemistry Course Synthesis of Heteroaryl Molecule I80-H53 through Palladium Catalyzed Heteroarylation
No full text2021 Celebration of Student Research and Creativity presentation"Our research focused on the properties of several heteroaryl molecules which had never been synthesized in the hopes that they will help find better treatment for breast cancer. 2.4 NaOtBu, 2% XPhos Pd Gen 4, 1.1 tropinone (I80), 1 heteroaryl (H53), and 2 mL of toluene molar equivalents were used in the synthesis. This mixture underwent microwave irradiation to produce the heteroaryl tropinone product. This product was purified using acetone centrifugation and acid-base extraction and then identified using NMR. The synthesized molecule may be able to function as an aromatase inhibitor and help treat hormone receptor- positive breast cancer."https://youtu.be/SrImV-IM7t
Domestic Violence
No full text2021 Celebration of Student Research and Creativity presentation"Domestic violence is a large social problem in our world. Children are often witnesses of domestic violence (DV). Research shows children exposed to DV experience negative impacts on future adult relationships. The purpose of this study is to examine what extent witnessing dv as a child impacts relationship as an adult. Information obtained from this research will potentially be used to inform social work practice and community partners."https://youtu.be/_LgN7Nd1Hq
Coping mechanisms used by college students struggling with anxiety
No full text2021 Celebration of Student Research and Creativity presentation"Anxiety is a common mental health concern that affects all races and genders.
Research suggests that everyday behaviors used to cope with anxiety can reinforce maladaptive functioning. The purpose of this study is to examine the common behaviors college students use to cope with their anxiety. This exploratory, cross-sectional study uses non-probability sampling and a self- administered, electronic survey. The results from this study are expected to show that college students often use maladaptive coping strategies when faced with anxiety provoking situations. Findings of this study may highlight the need for further intervention and psychoeducation as it relates to coping behaviors."https://youtu.be/C8tEBuijfR
Course-Based Undergraduate Research (CURE) Integration Increases Student Overall Success
No full text2021 Celebration of Student Research and Creativity presentation"Traditional learning in undergraduate STEM degrees is not always conducive to all learning styles, especially when it comes to performance in a lab environment. Course- based Undergraduate Research Experiences (CURE) allow a broader range of students the opportunity to participate in scientific research, while also engaging these students in a new style of learning. Northern Kentucky University implemented CURE labs to embrace real- world techniques and give drive and meaning to the work that each student performs in the lab. Ultimately, CURE labs improve students’ success in STEM and in college, as well as make research more accessible to a broader scale."https://youtu.be/kRIt9rstag
Substance Use Disorder and Treatment
No full text2021 Celebration of Student Research and Creativity presentation"Medically Assisted Treatment (MAT) can be a lifesaving tool for those who suffer from Substance Use Disorder, yet research suggests that there is considerable stigma associated with MAT. This cross-sectional study will use an electronic survey to examine people’s knowledge and support of MAT. The expected results will show that individuals have limited knowledge of MAT and that there is also limited support for the use of this treatment option. Social workers may use these findings to raise awareness about this effective treatment strategy."https://youtu.be/u9cRzapANW
Identification of the enzyme required for the acp3U modification in plastidic tRNA
No full text2021 Celebration of Student Research and Creativity presentation"Posttranscriptional tRNA modifications are essential for protein translation and proper cell growth. Defects in human tRNA modifications are associated with diseases such as cancer, type two diabetes, neurological disorders, and mitochondrial-linked disorders. The 3-amino-3 propylcarboxyuridine (acp3U) modification on tRNA is found in bacteria, plants, and animals, but not in yeast. DTWD proteins were recently identified as the enzymes responsible for acp3U modifications on eukaryotic tRNA. DTWD2 was shown to be responsible for the acp3U modification at residue 20a in human cells. We determined that DTWD2 forms acp3U20a in D. melanogaster cells. In A. thaliana, there are three homologs of human DTWD2 which are DTWD2A (AT2G41750), DTWD2B
(AT5G54880), and TapT-like
(AT1G03687). Our lab was able to identify that the aspartate and tryptophan residues of the DTWD2A protein in A. thaliana are required for modification activity and we were able to determine that it forms acp3U at position 20b on the tRNA. This was determined by expressing A. thaliana tRNA and A. thaliana DTWD2 genes in trm1Δ met22Δ yeast cells and testing by primer extension with fluorescent oligonucleotides. It is the current aim of this work to utilize the methods used to identify DTWD2A as the enzyme responsible for acp3U at position 20b to identify the substrates of the DTWD2B and Tap-T like proteins. From this research we hope to better understand gene expression in multiple model
multicellular eukaryotes."https://youtu.be/2spZHQokLg
Analysis of COVID-19 Vaccine Brand Sentiment on Twitter
No full text2021 Celebration of Student Research and Creativity presentation"During March and April, 2021, we collected tweets that contain both a COVID keyword and a vaccine keyword, using the Twitter free streaming API. In this work we focus on analyzing the tweets collected during the week, April 1 – April 7. Each tweet was placed in one or more subsets of tweets based on particular vaccine brand keyword that it contains. Using this approach, we created eight tweet subsets (non-disjoint) for the following COVID vaccines:‘Johnson and Johnson’, ‘AstraZeneca’, ‘Pfizer’, ‘Moderna’, ‘Novavax, ‘Sputnik’, ‘Sinovac’, and ‘Covaxin’. For each subset, we computed the number of tweets per unit of time and the average sentiment score of the tweets during that time window, using a publicly available lexicon-based technique (TextBlob). We visualize both the count and
average sentiment values for all 8 vaccine types."https://youtu.be/kzqDbouiip
Prevalence of Undergraduate Emotional Intelligence Instruction at Kentucky Public Universities
No full text2021 Celebration of Student Research and Creativity presentationResearch demonstrates that emotional intelligence (EI) is a primary factor in leadership and administrative success as well as a key component to organizational success; thus, undergraduate education in EI is a necessary component of undergraduate education in these disciplines. To explore the prevalence of emotional intelligence instruction in undergraduate settings, this study reviewed college of business and leadership undergraduate program curriculum at seven public universities in Kentucky: University of Louisville, University of Kentucky, Northern Kentucky University, Western Kentucky University, Eastern Kentucky University, Murray State University and Morehead State University. To identify the prevalence of EI instruction in these undergraduate programs, a document analysis of program catalogs and program websites was conducted. Findings indicate that there is a lack of required EI courses in the curriculum for students seeking degrees in business administration, management, or leadership.https://youtu.be/dwhdxpimoo
Rate of Incidence in Intimate Partner Violence in Same-Sex versus Mixed-Sex Couples
No full text2021 Celebration of Student Research and Creativity presentation"Despite the myth that intimate partner violence occurs exclusively in heterosexual couples, research suggests that incidence rates are comparable if not higher in same- sex couples. The purpose of this study is to examine the rate of incidence (ROI) of intimate partner violence (IPV) in same-sex couples versus mixed-sex couples. A brief, self – administered survey will be used to assess for sexuality and rate of incidence. Due to the limited research on this topic, it is essential to create a safe space where this subject
can be openly discussed and addressed"https://youtu.be/L4D6rFT8bn
NKU CURE-Course-Base Research Experience
No full text2021 Celebration of Student Research and Creativity presentation"Traditional laboratory class structures have focused on problems or ideas that have already been experimented. However, a novel approach to the restructure of laboratory classes has been brought up. It is called Course-based Undergraduate Research Experience or CURE. This is a laboratory class setting that focuses on exposing undergraduates to scientific research. In this laboratory class structure, students perform original research to potentially create bioactive molecules. Students enrolled in the CURE labs not only gain hands-on knowledge of modern equipment and digital tools used in organic chemistry research but also gain “soft” scientific skills such as scientific collaboration and communication[8]. Through studies, it has been shown that learning current research methods and skills increases student success. In addition, when CURE is compared to traditional and expository activities students have shown increased learning."https://youtu.be/DVMGXk7C1d