Internal Medicine and Medical Investigation Journal (IMMINV)
Not a member yet
148 research outputs found
Sort by
Determining the Prevalence and Types of Nail Involvement in Patients with Severe Acne Vulgaris Who Referred to Clinic of Dermatology of Rasoul-e-akram Hospital During 2010-2011
Full text linkIntroduction: Various skin diseases such as psoriasis, lichen planus, and alopecia areata can be associated with structural nail lesions. However nail lesions prevalence in patients with severe acne vulgaris is not determined. This study aimed to determine the frequency and types of nail lesions in patients with severe acne vulgaris.Methods: In this cross-sectional study, 235 patients with severe acne vulgaris were included from the clinic of dermatology of RasoulAkram Hospital during the years 2010 and 2011. The patients had no history of treatment for acne vulgaris. Patients initially underwent clinical examination, and severity of acne was determined among them. Demographic characteristics such as gender, age, and blood type, and Nail disorders including brittleness, Onycholysis, and Leukonychia were investigated in these patients. Data were analyzed using SPSS 18 software.Results:In this study79 patients with severe acne vulgaris (33.6%) had nail involvement and the frequency of nail lesions in this study was as follows: brittle nails 26.8% (63 cases); Leukonychia 18.2% (43 cases); Parrot beaked nails 3.4% (8 cases) and Onycholysis 1.3% (3 cases). Nail disorders in patients with severe acne vulgaris was not associated with sex, blood group, and the severity and distribution of acne lesions. But the lower age of the patients was associated with the incidence of nail disorders.Conclusion: According to high prevalence of nail involvement, especially brittle nails in patients with severe acne vulgaris, investigation and treatment of nail disorders in these patients have a great importance
Relationship Between Shock Index and Clinical Outcome in Patients with Multiple Traumas
Full text linkBackground: Initial assessment of hemodynamic parameters and timely management of patients regarding hypovolemic shock occurrence is the most essential clinical action in trauma patients and shock index (SI) has considerable accuracy associated with wide application. Therefore, this study is planned to evaluate the relationship of the shock index and clinical outcome in patients with multiple trauma referring to Shahid Sadoughi Hospital of Yazd in 2011.Methods: The present study was a descriptive cross-sectional study carried out on 334 patients with multiple trauma referring to Emergency Center of Shahid Sadoughi Hospital of Yazd in 2011. Patients were divided into two separate groups based on Shock index score (≥ 0.9 as abnormal SI and < 0.9 as normal SI).Finally, data were analyzed using Chi-square and independent sample t-test in SPSS ver.19.Results: There was significant difference between the two groups in terms of mean of and gender distribution (P= 0.001). There was also a significant difference between patients with head and neck trauma and pelvic injuries in terms of frequency distribution (P< 0.05). Hemodynamic parameters were also significantly different in the two studied groups (P< 0.001). Also, with regard to the frequency distribution of intensive care unit admission (ICU) and mortality rate, there was significant difference in the two groups.Conclusion: Shock index has considerable predictive value in patients with multiple trauma and can be used in initial management and assessment of patients with multiple trauma before any other diagnostic procedures since it is easily calculated. Shock index can also rapidly diagnose the real condition of trauma patient in primary hours and prevent secondary unpleasant clinical outcomes.
Investigating the Role of International Law in Controlling Communicable Diseases
Full text linkInternational law globally plays a key role in the surveillance and control of communicable diseases. Throughout the nineteenth century, international law played a dominant role in harmonizing the inconsistent national quarantine regulations of European nation states; facilitating the exchange of epidemiological information on infectious diseases; establishing international health organizations; and standardization of surveillance. Today, due to changed forms of infectious diseases and individuals' lifestyles as well as individuals' proximity caused by increased air travels, communicable diseases are in an international and cross-border form. In this regard, binding regulations and inconsistent rules adopted in international multilateral institutions like the World Health Organization, World Trade Organization, Food and Agriculture Organization can be of great use in surveillance and control of communicable diseases. With the globalization of public health, international law can be used as an essential tool in monitoring global health and reducing human vulnerability and mortality
Epidemiological, Clinical and Radiological Characteristics of Patients with Head Trauma
Full text linkIntroduction: Head injury has been recognized as a major public health problem and is a frequent cause of death and disability in young people and makes considerable demands on health services. Motor vehicle accidents are the major causes of traumatic brain injury (TBI) that its occurrence has been increasing in our country in recent years.Objective: We decided to study head injury in our region to evaluate the Epidemiological, clinical and radiological features of this health problem.Materials and methods: We reviewed 200 TBI-patients records in Ali ebn abitaleb hospital of Rafsanjan from November 2012 – September 2013. A Questionnaire including Age, Sex, Job, Cause of trauma, GCS, Brain CT Scan findings and clinical symptoms for every head trauma patient; was completed. Data were analyzed by SPSS software. We used Chi-square test and P-Value less than 0.05 was considered significant.Results: From the total of 200 patients, 73.5% were males and 26.5% were females. The most common age group was 20-24 years. Majority of patients were students. Traffic accidents were the major cause of injuries (64.5%) and 35.5% of them were motorcyclist. The most frequent finding of Brain CT scan was skull fracture and subdural hematoma. 25% of patient had severe head injury. In clinical symptoms in conscious patients, headache, nausea, vomiting and vertigo was common.Conclusion: This study showed that we should pay more attention to traumatic brain injury young patients who are the most active potential forces of our society. Traffic accident s are the major reason for head injuries. Pay attention to prevention of this accident can perform important role in decreasing of head injuries
Pain Management and Its Related Factors in the Emergency Department of Besat Hospital in Sanadaj, 2016
Full text linkAbstract:Background: Pain is a distressing feeling as well as a discomfort which triggers as the result of a special stimulation of nerve endings.This study aimed to investigate the amount of sufficient pain management among patients referring to the emergency department in Besat Hospital in the city of Sanandaj in Iran.Material and Methods: in this descriptive-analytical study, 175 patients with severe pain intensity higher than 3 and definite causes of pain with physical origins admitted to the emergency department were included. Before and after analgesics injection, pain intensity was assessed by a 10-point scoring system.Results: No significant correlation showed between pain intensity in patients, administration of painkillers, and age (P>0.05).There was a statistically significant relationship between pain intensity, gender, and the type of analgesics received (P<0.05). The findings of this study also revealed that reduction of pain was not significantly correlated with age, gender, referral time, and administration of painkillers on patients (P> 0.05).Conclusion: Failure to control pain among patients can lead to physical, mental, psychological, and social health-related problems. Therefore, proper examination of pains can provide suitable interventions in order to control and manage pains among patients and consequently promote their quality of life
Evaluation of Major Psychiatric Disorders in Patients in Rafsanjan, Iran, with Acne Vulgaris
Full text linkBackground: Skin health and mental health are highly correlated. Considering that less attention has been paid to multidisciplinary fields, we evaluated the prevalence of mental disorders and related problems in patients with acne vulgaris in the city of Rafsanjan, Iran.Methods: This was a cross-sectional study. The study population included all patients with acne vulgaris in Rafsanjan who were referred in 2016 to a skin and hair clinic. After the patients agreed to participate, they underwent a psychological interview. Using the Hamilton Anxiety Scale, Beck Depression Inventory, and suicide questionnaires, their data were recorded and collected. Data were then analyzed using the chi-square test and Fisher’s exact test.Results: Of 100 patients evaluated (48 women and 52 men), 8% had severe anxiety, 61% had moderate anxiety, and 31% had mild anxiety. Moreover, 64% of patients had mild depression, 29% had moderate depression, and 7% had severe depression. Of all patients, only one had a high risk for suicide attempts. We did not find any significant relationship between anxiety or suicide disorder and any of following variables: marital status, disease duration, amount of lesions, location of lesions, and expansion of lesions. We observed that with increasing duration of illness, expansion of lesions, and level of lesions, depression increased significantly in patients with acne vulgaris. Location of lesions was not associated with depression.Conclusion: The prevalence of anxiety and depression is high in patients with acne vulgaris. Acne disease is more significantly correlated with depression
Magnetic Resonance Imaging (MRI) findings in patients with brain small vessel disease
Full text linkBackground: Cerebral small vessel disease (SVD) affects small perforating arteries, causing both lacunar infarction (LI) and confluent white matter lesions (WML). Small vessel disease or lacunar infarct is one of the major stroke subgroups. Lacunar syndromes may be divided into two groups: the classic group (pure motor hemiplegia, pure sensory stroke, ataxic hemiparesis, dysarthria-clumsy hand syndrome, sensorimotor stroke) and the miscellaneous group, including all other lacunar syndromes. We have evaluated risk factors, clinical syndromes, topography, and laboratory findings of 101 consecutive patients with symptomatic lacunar infarcts diagnosed by magnetic resonance imaging.Methods: We analyzed 101 patients with clinical lacunar infarct syndrome who were referred to the neurology department of Qa’em hospital, Mashhad in the northeast of Iran. We assessed clinical features, sex, age, risk factors, radiologic findings and laboratory data of these patients.Results: The pure motor hemiparesis (53.5%) constituted the most usual lacunar syndrome. Mean age of the patients was 63.7± 8.5%. Diabetes mellitus was seen in 14 (13.9%) and hypercholesterolemia in 41 (40.6%) of patients. There were significant differences among ataxic-hemiparesis syndrome and hypertriglyceridemia and CVA history. There was a significant difference between miscellaneous syndromes and valve disease history. Also, there was significant correlation between WML and smoking. Thirty percent of the lesions were detected by CT scan.Conclusion: Sixty percent of the cases were associated with white matter signal changes. Diabetes mellitus were found in 14% of patients. Hypertriglyceridemia, CVA history and valve disease history were associated with some subgroups, but more investigations should be performed for precise assessment of other risk factors
Survey On Methanol Poisoning Epidemic in Rafsanjan City in Year 2013
Full text linkBackground: Examination and early detection of the methanol toxicity epidemic are very important, so identification and initiation of appropriate therapy can significantly reduce morbidity and mortality. Therefore, this study was aimed to investigation methanol poisoning epidemic in Rafsanjan city.Methods: This case series study was conducted in 252 patients with methanol poisoning in 2013 in the Ali-ibn-Abi-Talib hospital of Rafsanjan. Data were through interviews and records that were collected at hospital admission. Due to the large number of patients and the possible lack of ability of rapid measurement of serum levels of methanol and need of rapid intervention, treatment to reduce any further complications, early diagnosis and treatment were carried out by clinical history and interpretation of arterial blood gas test results. Data record on provided checklists and then analyzed using SPSS version 19.Results: The mean pH was 0.13±7.27. The most frequent clinical features were visual disturbances (39.7%), dyspnea (1.2%), and gastrointestinal symptoms (7.1%). There was a trend towards decreasing PCO2 with decreasing pH amongst the patients surviving. The opposite trend was demonstrated in the dying; the difference was highly significant by linear regression analyses (P< 0.001).Conclusions: Methanol poisoning still has a high morbidity and mortality, mainly because of late diagnosis and treatment. Respiratory arrest, coma and severe metabolic acidosis upon admission were strong predictors of poor outcome. Early admission and ability of respiratory compensation of metabolic acidosis were associated with survival
Correlation Between Body Mass Index and Echocardiographic Findings in Overweight Patients Compared to Normal-Weight Patients
Full text linkBackground: Overweight is currently considered as the main risk factor for various chronic disorders, especially cardiovascular diseases. Unexpected hypertension is the first reaction of heart to overburden imposed by obesity or overweight. The purpose of the present study was to evaluate the correlation between body mass index (BMI) and echocardiographic findings in overweight patients compared with normal-weight population.methods: This historical cohort study was conducted on 60 patients divided into two group of 30 based on their measured weights, group 1 with BMI of 20-25 kg/m2 as control and group 2 with 25<BMI≤30 kg/m2. All demographic and clinical data along with the echocardiographic findings were recorded for all samples.Results: The mean age of control (41.06 ± 12.82 years) and oversights (46.84 ± 12.61 years) was not significantly different (P = 0.067). Systolic blood pressure (P = 0.003) and pulse rate (P = 0.028) were significantly higher in overweight group; ejection fraction (P = 0.036), end-systolic (P < 0.001) and end-diastolic (P < 0.001) left ventricular dimensions, and left ventricular mass index (P = 0.005) were significantly higher in control group.Conclusion: Overweighting due to anatomical remodeling can cause diastolic heart failure in left ventricle. According to the relatively poor prognosis of treatment features in patients with probable risk factors of heart failure such as diabetes, hypertension and ischemic heart disease (IHD), it is recommended to consider overweight as an effective prognostic factor.
Common Variable Immunodeficiency (CVID): A Case Report
Full text linkCommon variable immune deficiency disease is the most prevalent acquired immune deficiency in human being after selective immunoglobulin A deficiency. It causes reduction of immunoglobulin levels and specific antibodies production and enhancement of recurrent and chronic infections risk, especially respiratory infections. CVID patients faces increased risk of granulomatous disease, autoimmune and phenomenon and malignancy. The disease involves males and females equally. Some studies showed that early diagnosis of CVID disease and regular treatment of patients with IVIG may have an efficient role in decreasing pneumonia and frequency of hospitalization due to infections and its complications. In this study we report a 16 years old girl with CVID, without clinical history of determined infection with recurrent sinusitis