Geological Observatory of Coldigioco

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    Insight into the description of van der Waals forces for benzene adsorption on transition metal (111) surfaces

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    Abstract Exploring the role of van der Waals (vdW) forces on the adsorption of molecules on extended metal surfaces has become possible in recent years thanks to exciting developments in density functional theory (DFT). Among these newly developed vdW-inclusive methods, interatomic vd

    A note on estimating a smooth monotone regression by combining kernel and density estimates

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    Abstract In a recent paper Dette

    Contribution to the inventory of lichens encountered in the reserve of Sidi Boughaba (Morocco)

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    ABSTRACT A study of the lichen flora encountered in the Sid

    On the set of distance between two sets over finite fields

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    We use bounds of exponential sums to derive new lower bounds on the number of distinct distances between all pairs of points (x,y) ∈ Ꮽ × Ꮾ for two given sets Ꮽ,Ꮾ ∈ F n q , where F q is a finite field of q elements and n ≥ 1 is an integer

    An industrial study on the risk of software changes

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    ABSTRACT Modelling and understanding bugs has been the focus of much of the Software Engineering research today. However, organizations are interested in more than just bugs. In particular, they are more concerned about managing risk, i.e., the likelihood that a code or design change will cause a negative impact on their products and processes, regardless of whether or not it introduces a bug. In this paper, we conduct a year-long study involving more than 450 developers of a large enterprise, spanning more than 60 teams, to better understand risky changes, i.e., changes for which developers believe that additional attention is needed in the form of careful code or design reviewing and/or more testing. Our findings show that different developers and different teams have their own criteria for determining risky changes. Using factors extracted from the changes and the history of the files modified by the changes, we are able to accurately identify risky changes with a recall of more than 67%, and a precision improvement of 87% (using developer specific models) and 37% (using team specific models), over a random model. We find that the number of lines and chunks of code added by the change, the bugginess of the files being changed, the number of bug reports linked to a change and the developer experience are the best indicators of change risk. In addition, we find that when a change has many related changes, the reliability of developers in marking risky changes is negatively affected. Our findings and models are being used today in practice to manage the risk of software projects

    Pamukkale Tıp Dergisi Pamukkale Medical Journal Evaluation of motor nerve excitability by subtreshold stimuli in diabetic polyneuropathy Diabetik polinöropatide eşik altı uyarilarla motor sinir eksitabilitesinin değerlendirilmesi

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    Abstract Purpose: The aim of this study is to evaluate motor nerve excitability in diabetic polyneuropathy. Materials and methods: Forty-five patients were enrolled and divided into 3 groups (Group I; diabetic patients without polyneuropathy, Group II; diabetic patients with polyneuropathy, Group III; healthy controls,). The stimuli were given to tibial nerve for 100μs with 5 mA increments starting from 5 mA up to the maximum of 100mA. The CMAP amplitudes appearing with each current of stimulus were divided into the maximum CMAP amplitude for each patient. This value is considered as the ratio of recruited motor units (RRMU) for that current. The mean value of the RRMU for each stimulus current in groups II and III were compared with the healthy controls. Results: The statistical analysis revealed no significant difference in diabetic patients in terms of nerve excitability with the subtreshold stimuli. Besides, the current that is needed to achieve the maximum CMAP amplitude did not differ between the groups. Conclusion: Giving subtreshold stimuli with increasing currents did not give additional information about motor nerve impairment in diabetic patients. Pam Med J 2013;6(3):144-14

    Cooperation or Competition: An Evolutionary Game Study between Commercial Banks and Big Data-Based E-Commerce Financial Institutions in China

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    On the premise of participants' bounded rationality and information asymmetry, this paper focuses on the cooperation or competition relationship between Chinese e-commerce financial institutions and commercial banks from the perspective of dynamic game. Theoretical mathematical model is built to analyze an evolutionary stable strategy under different conditions. We adopt real-life data set collected in Alibaba's network credit loan business case and Jingdong's supply chain financing business case to verify the evolution process of cooperation and competition relationship. The results show that (cooperation, cooperation) is bound to be the evolutionary stable strategy (ESS) and cooperation tends to be increasingly in-depth and expansive for commercial banks as well as e-commerce financial institutions in China. The complementarity of participants' core competitiveness is explored as the root of cooperation. Finally, strategic suggestions are put forward on cooperation between e-commerce financial institutions and commercial banks

    A Novel Ring Oxidation of 4-or 5-Substituted 2H-Oxazole to Corresponding 2-Oxazolone Catalyzed by Cytosolic Aldehyde Oxidase

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    ABSTRACT: The ring oxidation of 2H-oxazole, or C2-unsubstituted oxazole, to 2-oxazolone, a cyclic carbamate, was observed on various 4-or 5-substituted oxazoles. Using 5-(3-bromophenyl)oxazole as a model compound, its 2-oxazolone metabolite M1 was fully characterized by liquid chromatography/tandem mass spectrometry and nuclear magnetic resonance. The reaction mainly occurred in the liver cytosolic fraction without the requirement of cytochrome P450 enzymes and cofactor NADPH. Investigations into the mechanism of formation of 2-oxazolone using various chemical inhibitors indicated that the reaction was primarily catalyzed by aldehyde oxidase and not by xanthine oxidase. In addition, cytosol incubation of 5-(3-bromophenyl)oxazole in the medium containing H 2 18 O led to the 18 O incorporation into M1, substantiating the reaction mechanism of a typical molybdenum hydroxylase. The rank order of liver cytosols for the 2-oxazolone formation was mouse > monkey Ͼ Ͼ rat and human liver cytosol, whereas M1 was not formed in dog liver cytosol. Because the reaction was observed with a number of 4-or 5-substituted 2H-oxazoles in mouse liver cytosols, 2H-oxazoles represent a new substrate chemotype for ring oxidation catalyzed by aldehyde oxidase

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    RESUMO Objetivo. Determinar a relação entre os cochilos após o almoço e a atividade motora no período da tarde em crianças do ensino infantil. Método. Participaram do estudo, 42 crianças saudáveis com idade entre 4 e 5 anos de dois Centros Municipais de Educação Infantil (CMEIs) da cidade de Curitiba, Paraná. Em um deles (CMEI I), as crianças tinham a opção de cochilar ou não após o almoço enquanto no outro (CMEI II), todas as crianças eram estimuladas a cochilar. Cada participante usou um actígrafo por sete dias e sete noites para que seu ciclo vigília/sono e sua atividade motora no período da tarde fossem objetivamente mensurados. A fim de se comparar a atividade motora média das crianças após cochilarem ou não, todos os participantes foram mantidos acordados após o almoço em ao menos um dos dias da semana. Resultados. A atividade motora média das crianças correlacionou-se negativamente com a média de duração de seus cochilos (r=-0,46; p<0,05). A atividade motora média após as crianças cochilarem foi menor do que após ficarem acordadas no CMEI II (t=-2,33; p<0,03) mas não no CMEI I (t=0,96; p=0,35). Conclusão. Cochilos após o almoço diminuem a atividade motora de crianças de 4-5 anos de idade que frequentam Centros de Educação Infantil em período integral. Unitermos. Crianças, Educação infantil, Cochilos, Atividade motora, Actigrafia. Citação. Magalhães EF. Cochilos reduzem a rtividade motora de crianças de 4-5 anos que frequentam creches em período integral. ABSTRACT Objective. To determine the relationship between napping and the afternoon motor activity of preschool-aged children. Method. Participants were 42 healthy 4-5-year olds from two child care centers (CCCs) -one where children could choose whether or not to nap after lunch (CCC I) and another one where all children were encouraged to do so (CCC II). Each participant wore an actigraphy watch for seven days so that their sleep/wake cycle and afternoon motor activity were objectively measured. In order to compare the children´s mean afternoon motor activity on napping and non-napping days, all children were required not to nap on at least one weekday. Results. The children´s mean afternoon motor activity was negatively correlated to their mean nap duration (r=-0.46; p<0.05 ). The mean motor activity was smaller on nap days compared to non-nap days for the CCC II (t = -2.33; p<0.03) but not for the CCC I (t=0.96; p=0.35). Conclusion. After lunch naps reduce the afternoon motor activity of 4-5-year olds enrolled in full-time child care. Keywords. Children, Preschool, Sleep, Motor activity, Actigraphy. Citation. Magalhães EF. After lunch naps reduce the afternoon motor activity of 4-5-year old enrolled in full-time childcare. After lunch naps reduce the afternoon motor activity of 4-5-year old enrolled in full-time childcar

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