Geological Observatory of Coldigioco

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    The influence of the highway route on the development of patchwork of plots

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    Abstract When defining the patchwork of plots, based on the literature, it lists the types and subtypes, and given their prevalence in the studied villages. Characterized listed types and subtypes the patchwork of plots the adopted villages crossed by the highway, paying particular attention to the fragmentation of the parcels. Particular attention was paid to the occurrence of the patchwork of the outer of plots for the following reasons: firstly -the presence of plots owners do not reside in the surveyed villages (out-of-village owners) and living in the surveyed villages, but with land in other surveyed villages (local non-resident owners), which is an important issue approximately of plots owners to habitat in the complex work of consolidation and exchange of land; secondly -it allows for adjustment of the boundaries of the village, which destroys the highway without immediate execution merge. This should make such a correction using only the exchange of land; thirdly -crossing the village highway of plots prevents access to out-of-village owners and local non-resident owners when their habitats are located on the opposite side thereof. The study of this problem are designed the patchwork table method to both the external patchwork of plots and internal patchwork of plots. Conducting research in this field mapping method was used to present the occurrence of the external patchwork of plots and the internal patchwork of plots on the cadastral maps

    prophylactic

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    Abstract The aim of the present study was to compare the antiemetic effect of intravenous Granisetron, Ondansetron & Metoclopramide in a randomized blinded study for prophylaxis of post operative nausea and vomiting (PONV) in patients undergoing laparoscopic cholecystectomy under general anaesthesia. 60 patients (ASA I & II) undergoing laparoscopic cholecystectomy under general anaesthesia were randomly allocated into three equal groups (n=20). Emetic episodes in first 24 hours were recorded and compared in different study groups. Results were analyzed. Minimal emetic episodes were observed in early post-operative period (1-12hrs) in patients who had received intravenous granisetron in comparison to ondansetron and metoclopramide. However, after 12 hours emesis free periods were statistically insignificant between group A and B while patients in group C had no antiemetic effect

    Maternal plasmamiRNAs expression in preeclamptic pregnancies. BioMed research international

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    Objective. Preeclampsia (PE) is a pregnancy-specific syndrome and one of the leading causes of maternal and fetal morbidity and mortality. The pathophysiological mechanisms of PE remain poorly known. Recently, circulating miRNAs are considered as potential useful noninvasive biomarkers. The aim of this study was to identify differentially expressed plasma miRNAs in preeclamptic pregnancies compared with normal pregnancies. Methods. Maternal plasma miRNA expression profiles were detected by SOLiD sequencing. Differential expressions between mPE/sPE and control group were found. Next, four differentially expressed plasma miRNAs were chosen to validate their expression in other large scale samples by real-time PCR. Results. In terms of sequencing results, we identified that 51 miRNAs were differentially expressed. Four differentially expressed plasma miRNAs (miR-141, miR-144, miR-221, and miR-29a) were selected to validate the sequencing results. RT-PCR data confirmed the reliability of sequencing results. The further statistical analysis showed that maternal plasma miR-141 and miR-29a are significantly overexpressed in mPE ( < 0.05). Maternal plasma miR-144 is significantly underexpressed in mPE and sPE ( < 0.05). Conclusions. Results showed that there were differentially expressed maternal plasma miRNAs in patients with preeclampsia. These plasma miRNAs might be used as notable biomarkers for diagnosis of preeclampsia

    Hypothesis and conceptual framework Development of Cross Cultural Training and Perceived Success of Expatriates

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    ABSTRACT Rising trends of globalization in economic, managerial and social arenas have resulted in interpersonal contacts across the cultures. Multinational companies are increasingly focusing on trainings of their employees for improvement of performance. This research is based on the practical idea and literature review about the success of employees who are deputed for overseas assignments. Various factors related to the success or failures of expatriates have been explored in this study and one of the important aspects "cross cultural training" has been focused to find its impact on success of expatriates. This study encompasses the definition of cross cultural training ranging to its importance and effects. Substantial investment pertaining to foreign subsidiaries fashions the management to expect for the high returns, on the other hand, failure of expatriates adds significantly in failure of companies in deed. Proper cross cultural training of employees help them to shun the cultural shock and difficulties in adjustment abroad. For completion of this research, a very comprehensive questionnaire was designed basing on theoretical framework and a case study of expatriates of National Database and Registration Authority (NADRA) of Pakistan was carried out. Study found that there are multi-faceted uses of cross cultural training and it is one of the major sources to reduce cultural shock and premature return of the employees. The research is not only useful for NADRA and Government Sector of Pakistan rather through conceptual work it is universally constructive for developing a general idea about cross cultural training and its impact on success of expatriates. This research specifically covered all related areas of expatriates of studied organization and findings have been discussed in order to grasp the relevant sides of topic by controlling rest of variables for getting potentially reliable results

    Atherogenic Index of Plasma(AIP) in Post Menopausal Women

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    ABSTRACT Menopause is the phase of declined ovarian activity & fall in estrogen level. Since there is an increased risk of cardiovascular diseases for women after menopause, the present study was carried out to evaluate the lipid profile status and Atherogenic index of plasma (AIP) in Postmenopausal women. Blood samples from 30 premenopausal and 30 post-menopausal women were collected for this study. Atherogenic index of plasma a risk for coronary heart disease was calculated using the formula log (TG/HDL-C). There was significant increase in TC, LDL-C, TG and significant decrease in HDL-C (p<0.01) in post-menopausal women compared to pre-menopausal women. The (AIP) was found to be significantly elevated in post-menopausal women compared to pre-menopausal women and correlated positively with TG (r= 0.258,p<0.01) and negatively with HDL-C (r= -0.306, p<0.01) in postmenopausal women. This suggests that female sex steroids in "pre-menopausal" women has plasma cholesterol lowering action, where as in post-menopausal women due estrogen deficiency causes increase in serum cholesterol levels. Hence "post-menopausal" women are more prone for coronary artery disease compared to premenopausal women

    A Probabilistic Model for Evaluating the Operational Cost of PKI-based Financial Transactions

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    Abstract. The use of PKI in large scale environments suffers some inherent problems concerning the options to adopt for the optimal cost-centered operation of the system. In this paper a Markov based probability model has been applied and a performability indicator has been introduced for assisting the evaluation of the operational cost of the system in a decision support process. Considering the unavailability of the Certification Authority server, three different strategies have been evaluated for determining the optimal one

    The Jihadist Complex

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    Abstract Objective: This is an exploratory review of the literature to map out the characteristics of the jihadist complex as a tool for understanding the conduct better than we do now. I assessed the factors leading to youth disenfranchisement to determine whether they were contributory push factors among the youth that are attracted to jihadist causes. What are the modalities for reducing some of the underlying causes of radicalism in the Sub-region and elsewhere? Method: For the theoretical analyses, I relied on five thematic areas theorized by various security researchers that jihadist radicalism is youthful, that it is built on Islamic religious "narrative", that they are a disenfranchised rebels without a cause, that they are not empathetic towards the suffering of vulnerable Muslims, that due to these antecedents, radicals are "instrumentalized" by groups such as Al Qaeda or ISIS. Result: The result shows the literature on radicalism, jihadist terrorism is still emerging and suffers from the lack of systematic epidemiologic formulation for the analyses of this social conduct. It appears there is confusion among researchers about whether the terrorist suffers from what can be described as "Jihadist Complex". Discussion: Jihadism is not an esoteric subject that should elude classification with regards to the behaviors of those engaged in this cause, since there is inherent stratification in the social backgrounds that the jihadists come from Africa, Asia, UK or Germany. Conclusion: To address a social challenge, one has to have the capacity to appraise the cause/effect aspect of the challenge on a given person or a group thereof. Jihadist push and pull factors can be understood and classified just as many human conducts are classifiable

    Genetically encoding phenyl azide chemistry: new uses and ideas for classical biochemistry

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    Abstract Introducing new physicochemical properties into proteins through genetically encoded Uaa (unnatural amino acid) incorporation can lead to the generation of proteins with novel properties not normally accessible with the 20 natural amino acids. Phenyl azide chemistry represents one such useful addition to the protein repertoire. Classically used in biochemistry as a non-specific photochemical protein cross-linker, genetically encoding phenyl azide chemistry at selected residues provides more powerful routes to post-translationally modify protein function in situ. The two main routes are modulation by light (optogenetics) and site-specific bio-orthogonal modification (bioconjugation) via Click chemistry. In the present article, we discuss both approaches and their influence on protein function. An expanded genetic code Uaas (unnatural amino acids) provide a powerful approach to expand the functionality of the proteome as they increase the chemical diversity sampled and introduce new physicochemical properties. The uses of Uaas are extensive and range from photocontrol [1,2] to biophysical probe

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