World Nutrition Journal (Indonesian Nutrition Association - INA)
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The narrative review of recent studies in understanding the relationship between gut (microbiota)-brain axis, nutrition and cognitive function
The concept of the gut (microbiota)-brain axis, which influences the development and function of the gastrointestinal, immune, neuroendocrine, and metabolic systems, is gaining popularity. Recent animal studies have demonstrated that the gut (microbiota)-brain axis also plays a role in establishing cognitive function. It is known that a disruption in the environment's microbiota balance can increase disease susceptibility in children. Historically, it has been hypothesized that neurodevelopmental disorders are the results of a disruption in children’s health. However, it is becoming clear that the gut microbiota and the central nervous system communicate in both directions, which could explain how microbiota affects cognitive function. Dietary factors also play important role in the central nervous system via the gut (microbiota)-brain axis, demonstrating the importance of nutrition in optimizing cognitive function. This narrative review of recently published studies and current knowledge aims to elucidate the relationship between the gut (microbiota)-brain axis and cognitive function, as well as the variables that may influence it
Enhancing patient care: Ethical considerations for micronutrient management in hospital nutrition settings
Micronutrients are represented by vitamins and minerals and are present in a wide variety of foods. Each of these nutrients performs specific functions that are essential for the health of our cells and their harmonious functioning. Data suggest that many people have an inadequate daily intake of micronutrients, even when nutritious food is more easily available. It has since been established that the complex, integrated immune system needs multiple specific micronutrients, including vitamins A, D, C, E, B6, and B12, folate, zinc, iron, copper, and selenium, which play vital, often synergistic roles at every stage of the immune response
Iron deficiency and its impact to children’s cognitive and development
Children are born to learn, and they develop and learn very quickly in their early years. Brain development milestones in children aged 0-5 years and Iron plays an important role in many neurodevelopmental processes, and animal studies have shown that adequate iron requirements in pregnancy and childhood are critical for a child's brain and neurodevelopment
Metabolic effects of monounsaturated fatty acid−enriched diets on glycaemic control in patient with type 2 diabetes: an evidence-based case report
Introduction: Diabetes mellitus type 2 (T2D) is the most common type of diabetes. There is an ongoing debate as to whether nutrient quality or quantity is mainly responsible for the effects on hyperglycaemic control of patients with T2D. Monounsaturated fatty acid (MUFA) has a metabolic effect in reducing the risk factor for metabolic syndrome to prevent and control hyperglycaemia in patients with T2D and is recommended by professional organizations.
Methods: Literature searching was conducted by advanced searching in Pubmed, Cochrane Library, Scopus, and ProQuest database using MeSH Terms combined with Title/Abstract. After removing duplicates, the literature were screened based on the eligibility criteria. Critical appraisal and level of evidence of the selected literature were determined based on Oxford Centre for Evidence-Based Medicine.
Results: Two selected literature were relevant to answer our clinical question, both literature are systematic review/meta-analysis studies. The first literature is a study by Fumiaki et al. (2016), while the second is by Frank Qian et al. (2016). All literature provided evidence that a diet high in MUFA could improve glucose-insulin homeostasis among patients with T2D. These effects were marked by lower fasting blood glucose and haemoglobin A1c (HbA1c), and insulin level in the enriched MUFA diet group compared to PUFA.
Conclusion: Nutrient quality is mainly responsible for the effects on glycaemic control profile in patients with T2D, with a high MUFA diet consistent with favourable effects to improve fasting glucose and HbA1c
Experts’ Opinion on Immunity and Nutrition to Support Key Cognitive Functions
The interaction of micronutrients and macronutrients has been shown to have a significant impact on children's cognitive development. Furthermore, proper nutrition helps a child's immune system avoid infection and disease, which can impair nutrient absorption and lead to deficiency. Microbiotas in the gut play critical roles in body physiology, including nutrient absorption, infection resistance and immune system development. Furthermore, it is known that the gut microbiota influences immune cell maturation. Finally, these three factors are thought to influence neurogenesis and cognitive development. A virtual meeting was held with five invited experts to gain a better understanding of the relationship between nutritional factors, the immune system and cognitive development
Nutrition and inflammaging : unveiling the impact of diet on healthy aging
Aging is a declining process which leads to a poorer state of human health. The process involved immune system, known as immunosenescence, which is a multifactorial and dynamic process, involving both innate and acquired immunity. It is characterized by a progressive reduction in the ability to trigger immune responses against infections and vaccinations and lead to inflammaging. Immunosenescence plays a critical role in most chrocic diseases in older people, therefore, attempts are made to slow down or reverse the process
The role of symbiotic to treat diarrhea in a critically ill Guillain-barre syndrome patient with morbid and type 2 diabetes mellitus : A case report
Guillain-Barre Syndrome (GBS) is a serious post-infectious immune-mediated neuropathy, and the case is increasing every year, approximately 6 in 100.000 cases yearly. Several cases depend on mechanical ventilation (MV) and have diarrhea during treatment in the intensive care unit (ICU). This case report aims to describe the role of synbiotic supplementation in treating diarrhea in a GBS patient in intensive care unit (ICU)
Eating behavior and health-related quality of life among female students attending higher education during COVID-19 pandemic in Indonesia
Background: Female students attending higher education had lower Health-related Quality of Life (HRQOL) scores and their eating behavior, which is a key element of healthy lifestyle, had changed to become unhealthy as a result of the pandemic's mental effects. There has been no study assessing the asssociation between both during the pandemic in Indonesia, especially after controlling for other factors.
Objective : This study aimed to assess the association between eating behavior and HRQOL among female students attending higher education during Covid-19 Pandemic.
Methods: This was a cross-sectional online survey with 474 subjects aged 18 to 25. The Dutch Eating Behavior Questionnaire (DEBQ) was used to assess emotional, external, and restraint eating. HRQOL was measured using the SF-36 questionnaire, with the subscales Physical Component Summary (PCS) and Mental Component Summary (MCS). Additionally, sociodemographic data, screen time, sleep duration, nutritional status, and physical activity were collected. The data were analyzed using multiple linear regression.
Results: PCS was significantly associated with emotional eating (r = 0.279, p-value <0.001), external eating (r = 0.211, p-value <0.001), and restrain eating (r = 0.116, p-value = 0.012). Besides, emotional eating (r = 0.211, p-value <0.001) and external eating (r = 0.172, p-value <0.001) were also significantly associated with MCS score
Conclusion: During Covid-19 pandemic, the higher the emotional, external, and restraint eating behavior scores of the students, the higher their physical health-related quality of life. The higher the emotional and external eating behavior scores, the higher their mental health-related quality of life. 
Effect of probiotic supplementation on wound healing in postoperative patients: A case report and literature review
Background: Delayed wound healing, particularly in chronic wounds, is a significant global public health issue. The World Health Organization (WHO) reports that over 6 million people in the United States experience delayed wound healing annually, resulting in a healthcare cost of $25 billion USD. Probiotics, known for their anti-inflammatory properties, have potential in influencing skin immunity by facilitating the transfer of cytokines and immune cells from Peyer's patches to the skin. Nevertheless, the precise impact of probiotics on postoperative wound healing remains an area with limited research.
Objective: Determine the effectiveness of probiotic supplements in wound healing in patients with surgical wounds
Method: Literature search is done by advanced searching on Pubmed, Cochrane, Scopus, and EBSCOhost with eligibility criteria determined by the author.
Results: There were three articles relevant to clinical questions and eligibility criteria that had been established, consisting of one systematic review article from the randomized controlled trial (RCT) study and two RCT articles. The SR/MA article includes good-quality RCT studies. The SR/MA article showed insignificant results on the effect of probiotic administration on healing. The RCT article showed significant results on the effect of probiotics on surgical wound healing, but the confidence level was low in one of the articles.
Conclusion: Probiotic supplementation on wound healing in postoperative patients is not conclusive. This can be affected by the type of probiotic strain, dosage, duration of administration, and location of the surgical wound
Perioperative nutrition : ERAS special group discussion
Nutrition is one of the vital role in improving the healing and recovery after surgery, either preoperative (before surgery), intraoperative (during surgery), or postoperative (after surgery). The Enhanced Recovery After Surgery (ERAS) Society has published a multidisciplinary approach to perioperative care aimed at achieved early recovery for patients undergoing major surgery