Cosmos Scholars Publishing House: Journals Management System
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A Novel Heart Disease Prediction System using Deep Multi-Layer Perceptron and Optimal Feature Selection Mechanism
Full text linkDiagnosis and prognosis of heart disease (HD) are essential medical tasks for a correct classification, which helps cardiologists to treat the patient properly. The current medical system is unable to obtain the entire information from the heart disease database. It is difficult for a physician to analyze and diagnose chronic disease because it is a challenging endeavor. Hence this paper proposes a novel weight and bias tune deep multi-layer perceptron for heart disease prediction (WBTDMLP) with optimal feature selection using modified random forest (MRF). The proposed system comprised ‘3’ phases such as data preprocessing, feature selection, and HD prediction. Initially the HD prediction data is collected from the Cleveland dataset and the missing value imputation and data normalization is applied on the dataset to preprocess the dataset. Following that, the feature selection was performed by using the MRF algorithm. Finally, the HD prediction is done based on WBTDMLP approach and the parameters are tuned by Sobel sequence with Brownian random walk-based dragonfly optimization algorithm (SSBRWDOA). The results indicate that the proposed approach reaches 97.89% accuracy, which is relatively higher than existing methods
Antioxidant Activity of Ocimum gratissimum Stem Extract Mediated Silver Nanoparticles- An in Vitro Study
Full text linkSilver nanoparticles made from plant extracts have drawn a lot of interest because of the potential uses for them in nanotechnology and medicine. Ocimum gratissimum was used since the ancient past for its antioxidant, antibacterial, anti-inflammatory, and immunomodulatory properties and it has long been employed in herbal therapy. Ocimum gratissimum’s stem extract was used in several research to synthesize silver nanoparticles and assess their antioxidant properties. The antioxidant capacity of the stem extract is influenced by the phytochemicals found in it, including phenolic substances, flavonoids, and tannins. These phytochemicals have the ability to stabilize the synthesized nanoparticles and serve as reducing agents. The DPPH radical scavenging activity and Hydroxyl radical scavenging activity was used to evaluate the antioxidant activity of the synthesized silver nanoparticles. The results of the conducted assays shows that the Ocimum gratissimum silver nanoparticles has shown to possess significant antioxidant activity and can be used as a therapeutic alternative to the commercial antioxidant drugs
Challenges and Progress in Related Substance Method Development: A Review of Validation Protocols
No full textThe detection and quantification of related substances, including impurities and degradation products, are crucial for ensuring the quality and safety of pharmaceutical products. The development of robust analytical methods for related substances has faced numerous challenges, ranging from the complexity of pharmaceutical formulations to stringent regulatory requirements. This review highlights the key hurdles in related substance method development, including issues related to sensitivity, selectivity, and matrix effects, as well as the need for stability-indicating capabilities. It also examines the progress made in the field, particularly through the introduction of advanced chromatographic techniques such as UHPLC and SFC, and the coupling of mass spectrometry for enhanced sensitivity and specificity. The review further explores the role of automated method development and the adoption of standardized validation protocols guided by regulatory frameworks, alongside the application of Quality by Design (QbD) principles to optimize and ensure the robustness of analytical methods. Despite significant advancements, continuous monitoring, revalidation, and adaptation to emerging impurities remain critical for maintaining the reliability of these methods in pharmaceutical quality control
Bibliometric Analysis and Predictors of Citations for Publications of a Higher Institution
No full textPurpose: This study aims to depict the productivity and impact of publications affiliated with Jordan University of Science and Technology (JUST), and to identify bibliometric factors associated with the number of citations. Methods: Using keywords and identification numbers, Scopus and Web of Science were searched for all publications affiliated with JUST from 1987-2022. The retrieved data was imported, cleaned, visualized, and analyzed using stataIC 16, Excel 395 software, and VOSviewer software. The bibliometric analyses were conducted for types of publications, year of publications, type of journals, faculties, departments, faculty members, and most cited publications. Networking analyses were also conducted for international collaboration and keyword analysis using VOSviewer. Univariable and multivariable Poisson regression models were conducted to estimate the impact of several bibliometric factors on citation numbers. Results: A total of 16,830 publications were affiliated with JUST and published between 1986 and 2022. The total number of citations was 330,046. The average citation per publication was 19.6 and the institutional h-index was 165. Most publications were original articles (81.8%) and 71.7% were published in traditional (non-open) journals. Publication and citation numbers increased steadily, until 2013, and then exponentially, afterward. ? The Faculty of Engineering had the highest number of total publications (4,593), while the Faculty of Medicine had the highest number of total citations (148,384). Professor Yousef S. Khader ranks first as JUST's influential faculty? with 640 publications and 110,777 citations. Factors contributing to higher incidence rate for citations include years since publication, indexing in Scopus and WoS, reviews, publication in open-access journals, and collaboration. Network analysis revealed significant clusters of authors and keywords, with strong connections to the United States and Saudi Arabia. Conclusion: The productivity nd impact of JUST publications have improved annually for all faculties and departments. ?However, this improvement seems to be limited and can be explained by several factors. Further improvements in research productivity and impact are needed by implementing relevant strategies such as collaboration and interdisciplinary research, publishing in high-impact journals, considering open-access publishing, considering the potential societal impact of research, increasing visibility and reputation through appropriate affiliations, publishing review articles, and monitoring research output over time
Developing Micro-Enterprises Based on Traditional Culinary in the Face of COVID-19 Pandemic Disruption: Insights from Indonesia
No full textThe research aimed to develop a micro-enterprise business strategy in the traditional culinary field suitable for implementation during the COVID-19 Pandemic. Like many other business processes, traditional culinary micro-enterprises tourism sub-sectors in Indonesia have been affected by government policies for the last two years to curb the spread of COVID-19. However, the pandemic policy has a positive side. Business actors were forced to maximize their ability to innovate by transforming business strategies adaptable to conditions and changes in consumer behavior due to the pandemic. The qualitative approach using the library research data collection method was used in this study. The findings show that a micro business strategy appropriate during a pandemic in the traditional culinary field is characterized by three elements: locally sourcing ingredients and materials, using local traditional recipes, and the production process carried out according to local community cultural methods. This will be a form of empowerment based on locally available resources. This service concept can utilize digital technology support in product promotion, ordering, and distribution while adhering to strict health protocol standards. The theoretical implications resulting from the research can contribute to science in the field of tourism, especially those related to traditional food and beverage businesses. This study's importance lies in its practical relevance to traditional culinary micro-enterprises during situations similar to the COVID-19 pandemic, its emphasis on local empowerment and sustainability, and its integration of digital technology. The study will expand new business model for traditional culinary micro-enterprises that can be implemented during the pandemic
Investigation of the Comorbidity of Bronchial Asthma and Allergic Rhinitis in Children
No full textToday there is an increasing tendency for all allergic diseases, including a high prevalence of bronchial asthma (BA), as well as an increasing number of patients with co-morbidities. Allergic rhinitis leads in frequency of occurrence with bronchial asthma. In the last decade, the term comorbidity has often been used to define the interrelation as well as the mutual influence of 2 or more syndromes, diseases in one patient. The aim of the research was to study the comorbidity of bronchial asthma and allergic rhinitis in children in the Department of Pulmonology. The retrospective study included an analysis of 51 case histories of children diagnosed with atopic bronchial asthma. Of the 51 patients, 28 children (54.9±7%) were diagnosed with allergic rhinitis after examination by an ENT specialist
The Acceptance of The Orang Asli Community's Movement Preachers Towards the Construct of Self-Preparation in Dakwah
No full textThe community mobilizers for the Orang Asli community are preachers who carry out the missionary work of the Department of Islamic Development Malaysia (JAKIM) in Orang Asli villages. However, do they have sufficient preparation in carrying out the missionary task towards the Indigenous People in the hinterland? This article attempts to analyse the acceptance of Indigenous Community Mobilizers towards items within the construct of self-preparation in preaching. This study is a quantitative research using a survey research design. A total of 140 respondents were selected as the study sample involving all Indigenous Community Mobilizers in Malaysia who have served for more than 5 years. A total of 10 items within the construct of self-preparation were asked to the Indigenous Community Mobilizers. The research data were analysed using SPSS software based on frequency, percentage, and mean. The study results indicate that all 10 items within the construct of self-preparation received approval from the Indigenous Community Mobilizers with a minimum average score of 4.51, indicating a very good level. The implication of the study is that preachers require sufficient self-preparation to carry out preaching duties in the field
Effect of Postnatal Care-Supportive Education on Knowledge, Willingness and Utilization of Postnatal Care Services among Pregnant Mothers in Rural Areas in Ebonyi State, Nigeria
No full textPostnatal care is a crucial aspect of maternal and child health, reducing maternal and newborn deaths. However, it is often neglected in the healthcare system. This study aimed to investigate the impact of postnatal care-supportive education on knowledge, willingness, and utilization of PNC services among pregnant mothers in rural areas of Ebonyi State, Nigeria. The research involved six objectives, two hypotheses, and a quasi-experimental design. The study used multistage and simple random techniques to select local government areas and health facilities, while purposive sampling was employed to select 225 pregnant mothers. A pretested questionnaire was used for data collection, with a content validity index of 0.92 and a reliability coefficient of 0.84. Data analysis was conducted using SPSS version 25. The results showed that 94.7% of respondents were Christians, 10.7% attended tertiary institutions, and 16.4% were civil servants. Pre-intervention, pregnant mothers had low knowledge of available PNC services and associated risks, but their knowledge improved significantly post-intervention. Factors such as education, age, and occupation were significantly associated with mothers' knowledge. The study also found low utilization of PNC services at baseline, with only 18.0% using services adequately in previous deliveries and 27.1% not using at all. Mothers demonstrated good willingness to utilize PNC services in subsequent deliveries. The study recommends that skilled healthcare workers provide adequate and well-prepared health education to mothers during antenatal and postnatal clinics to create awareness and make them understand the benefits of PNC services, ultimately improving utilization and reducing maternal and newborn deaths
Assessment of Asphalt Binder Characteristics Enhanced by Wheat Straw Ash (WSA) and Waste Engine Oil (WEO)
Full text linkEvery year, tons of agricultural waste ash from crop residues (such as Wheat straws) are generated through energy production activities. The disposal of this ash in landfills and through open dumping poses serious environmental and health problems, primarily due to groundwater contamination. Additionally, the lack of available land for further dumping exacerbates the issue. The disposal of large amounts of waste products such as Wheat Straw Ash (WSA), and Waste Engine Oil (WEO) presents significant environmental risks, including air and water pollution, along with the challenge of limited space for safe disposal. Utilizing these waste materials in asphalt binder not only enhances asphalt properties but also mitigates environmental issues. In this study, WSA at concentrations of 2%, 4%, and 6% were mixed with 2% WEO to modify virgin bitumen. The modified binder specimens were evaluated using the Bitumen Bond Strength test and Rolling Bottle test, along with conventional testing methods, to assess adhesion and moisture susceptibility. The experimental results indicate that bitumen modified with 2% WEO by weight of virgin binder exhibits better adhesion and moisture susceptibility compared to the control binder
Optimizing Safety, Sustainability, and Efficiency in Chemical Supply Chains in Sub-Saharan Africa: A Comprehensive Analysis of Best Practices and Digital Innovations
Full text linkThe management of chemical supply chains presents significant challenges in balancing safety, sustainability, and operational efficiency. This study analysed best practices and digital innovations in optimizing these aspects, with a particular focus on the chemical industry in sub-Saharan Africa. A mixed-method approach was adopted, utilizing a structured questionnaire survey of 1,600 personnel from chemical industries, yielding an 86% response rate (1,376 respondents). Quantitative data were analysed with Microsoft Excel using descriptive statistics, correlation, regression, factor analysis, and ANOVA to explore relationships between digital innovations, safety protocols, sustainability practices, and operational efficiency. The findings indicate that companies adopting digital innovations such as IoT, predictive analytics, and sustainability measures experienced up to 25% reductions in hazardous incidents and a significant improvement in supply chain efficiency. The review findings further revealed that sustainability practices such as emissions reduction, resource management, and circular economy models have become vital to addressing environmental concerns and aligning with regulatory requirements. By adopting these innovations, chemical companies can enhance not only their profitability and competitive edge but also their adherence to societal and environmental expectations. This research underscores the importance of digital transformation and sustainability for enhancing safety and compliance with international regulatory frameworks while also improving profitability