Cosmos Scholars Publishing House: Journals Management System
Not a member yet
1952 research outputs found
Sort by
EFFICACY OF ULTRASONIC TRANSDERMAL PLATELET RICH PLASMA ON CHRONIC LOWER LIMB VENOUS ULCER HEALING
The present study was carried-out to examine the impact of Ultrasonic Transdermal Delivery of platelet rich plasma (PRP)on chronic lower limb venous ulcer healing. Design: Randomized controlled trial. Patients and methods: The present work was conducted on sixty patients with chronic lower limb venous ulcers who took-part in this study, they aged from 40 to 60 years. The participants were recruited from Mataria teaching hospital and were randomized into two groups; each group consisted of 30 patients. Group A (Ultrasonic PRP group) received Ultrasonic Transdermal Delivery of autologous PRP twice weekly for a month in addition to medical care and group B (Control group) received medical care in form of antimicrobial dressing, wound care and debridement of ulcers. Saline method was used to measure the ulcer volume. Digital photography/imaging and surface area estimation software (Image J) was used to measure ulcer surface area. Results: After treatment, there was significant decline in wound surface area as well as volume of PRP group in comparison with the control group (p < 0.001). Conclusion: Adding Ultrasonic transdermal delivery of platelets rich plasma to medical treatment of chronic venous ulcer can enhance healing process by reducing surface area and ulcer volume and it is considered a safe, simple, inexpensive and cost effective modality
Formulation and Evaluation Study of Polyherbal Formulations towards Antidiabetic, Antilipidemic and Water Intake
Present investigation has to undertake for estimation of Antidiabetic, antilipidemic and water intake study in Polyherbal formulation. Total flavonoid content was64.01 mg/ml which is catechin equivalent, while Total phenolic content was 142.20 mg/ml, it shown strong anti-oxidant properties are indicated by the relatively high gallic acid content. The polyherbal juice's DPPHactivity was found to be 68.45% and for polyherbal formulations A and B to be 55.04% and 58.85%. The RC50 value for the DPPH scavenging assay was reported to be 6.0 g/ml. Quantitative Analysis of Phytoconstituents in Formulation was carried out using preliminary phytochemical assays and HPTLC
Assessing the Optimal Digital Banking Model for Service Users in Thailand: A Structural Equation Modelling Approach to Risk Analysis
Purpose –This study investigates the factors that influence the adoption of internet banking in Thailand. It specifically examines the interplay between six dimensions of perceived risk (financial risk, performance risk, privacy risk, security risk, social risk, and time risk), attitude, and trust, and their impact on behavioral intentions to use internet banking.Design/methodology/approach –A multi-stage sampling process was used to obtain a representative sample of 505 respondents in Thailand. Structural Equation Modeling (SEM) was used to analyze the data.Findings –The research outcomes suggest that the adoption and usage of internet banking services are influenced by several key factors, namely perceived risk, attitude, and trust. These factors play a significant role in shaping individuals' decisions and behaviors when it comes to engaging with online banking platforms. The findings also show that attitude and trust mediate the relationship between perceived risk and behavioral intention. Practical implications of this study extend to two key groups: internet banking developers, who can leverage the insights from this research to design user-centric systems aligned with the needs and lifestyles of their target users, and CEOs, who can establish effective and operational strategies and regulations to provide a competitive advantage for their organizations. Originality/value –This study contributes to the existing literature on internet banking adoption by providing a comprehensive understanding of the factors that influence this behavior. It also provides insights for internet banking developers and CEOs on how to design and promote internet banking services in a way that minimizes perceived risk and maximizes attitude and trust
Composting of Gambir Industrial Leaf Waste with the Addition of Cow Rumen and EM4 Activator using the Open Bin Method
Gambir is included in the ten main export commodities of West Sumatra Province. The high production of gambier in West Sumatra produces solid waste in the form of remaining gambier leaves from the extraction process in the gambier industry which needs to be processed. This study aims to analyze the quality and quantity of compost from the gambier industrial solid waste in the form of gambier leaves (DG) from the production process. Composting using the open bin method with variations in the addition of cow rumen (RS) and EM4 bioactivator. This study consisted of six treatments, namely treatment 1 100% DG, treatment 2 100% DG + 200 mL EM4, treatment 3 50% DG + 50% RS, treatment 4 60% DG + 40% RS, treatment 5 70% DG + 30 % RS, treatment 6 80% DG + 20% RS. All composting treatments are given the addition of rice husks as a bulking agent so that the resulting compost becomes loose. Each composting treatment was carried out in duplicate. The results of all treatments for compost maturity with parameters of temperature, pH, color have met the SNI 19-7030-2004 standard with 44-70 days of composting time. The results of the compost quality analysis showed that all treatments met the SNI 19-7030-2004 standards regarding compost specifications from organic waste for parameters of moisture, C-organic, nitrogen, C/N ratio, phosphorus, and potassium except for the results of composting treatment 1 did not meet This C-organic parameter can be caused by treatment 1 there is no addition of raw materials or bioactivators. The quantity of solid compost yields 50-70% of the compost raw material. Composting with treatment composition 3, namely a mixture of 50% gambier leaves and 50% beef rumen is the composition of the fastest composting in composting with a long composting time of 44 days with the highest quality of composting results, namely 70.19% with a C/N ratio of 17.94%, P 0,38%, K 8.70% so that based on the scoring results obtained treatment 3 is the best composition
Pag-Hinusayay: Unveiling the Unwritten Customary Laws and Settlement Practices of Panay Bukidnon Community
The Panay Bukidnon tribe's unique dispute resolution processes, deeply rooted in their cultural heritage, demonstrate a historical exercise of power by recognized elders and village emissaries within the community. The significance of exploring these laws and settlement procedures lies in unraveling a previously unknown aspect of Panay Bukidnon culture. Hence, this study was conducted to investigate the unwritten customary laws and settlement practices in Barangay Minan, Tapaz, Capiz, Philippines. This study adopts a qualitative research methodology with a narrative approach, aiming to gain insights into the unwritten customary laws and settlement practices of the Panay Bukidnon community. The respondents of the study were selected using the purposive sampling technique, specifically targeting four (4) magurangs or elders from the Panay Bukidnon community. Thematic analysis of the study showed that the role of the Manug-husay is a generational responsibility, ensuring the continuity and transmission of knowledge regarding dispute resolution and settlement practices. They have many practices so different from others and learning their rich tradition is a balm for knowledge seekers and peace settlers. These unwritten customary laws and settlement practices have also remained unchanged over generations, symbolizing the resilience and preservation of cultural heritage
The Effects of Taxpayer Education Programs on Voluntary Tax Compliance amongst SMEs in the Fast Foods Industry in Zimbabwe: Systematic Literature Review
This literature review critically assesses the impact of taxpayer education programs on tax compliance by Small and Medium Enterprises (SMEs) in Zimbabwe's fast-food industry. Given the sector's economic importance, the study aims to synthesize existing research on how these programs affect SMEs' understanding of tax regulations, awareness of compliance benefits, and intentions to comply. It systematically analyses methodologies, findings, and limitations of prior studies, employing meta-analysis for quantitative research and qualitative assessment for deeper insights. This review highlights the potential of taxpayer education to enhance voluntary tax compliance among SMEs in Zimbabwe's fast-food industry. Its findings have implications for policymakers, tax authorities, and practitioners seeking to improve tax compliance strategies. These insights can inform more tailored and effective educational interventions, ultimately benefiting government revenue, business sustainability, and economic growth in Zimbabwe
Integration of Wetland Technology for Sustainable Urban Development
The wetland technology has been derived from the concepts taken from the functions and services provided by natural wetland ecosystem. This study investigates the role of Wetland Technology Integration (WTI) for promoting Sustainable Urban Development (SUD). The research aims to assess the impact of WTI on water quality improvement, identify obstacles and opportunities and evaluate its influence on social, economic and environmental dimensions. This research employs a cross-sectional study design to assess WTI in urban development of Patna. Stratified random sampling ensures equitable representation across stakeholder group. A comprehensive questionnaire gathers data on water quality, and social, economic, and environmental impacts from 295 participants, facilitating a holistic understanding of present integration practices. The study revealed significant improvements in specific Water Quality Parameters (WQPs) in integrated area, affirming the positive effect of WTI on water quality. Regression models demonstrated a positive relationship between WTI and social, economic and environmental impact, indicating its favourable influence on urban sustainability. WTI in urban development holds promise for enhancing water quality and strengthens sustainability. The study’s outcomes offer insights into the multifaceted benefits of WTI and underscore the importance of overcoming challenges
Gemcitabine (A Chemotherapy Medication) Vs. Phytochemicals Against Non-Small Cell Lung Cancer – A Computational Approach
Non-small cell lung cancer is a type of lung cancer, where healthy cells in the lungs grow out of control forming a tumor or a nodule. Although small cell lung cancer and non-small cell lung cancer share few common symptoms and causes, their rate of spread or metastasis differs significantly. Targeted gene therapies involving uses of targeted drugs against specific gene or protein are increasingly being used for the treatment of lung cancer. This study aims at understanding the efficacy of the bioactive compounds over the already existing chemotherapy drug- Gemcitabine. For this study, the target receptor proteins of Non-Small Cell Lung Cancer (NSCLC) were retrieved from Protein Data Bank (PDB) and the ligand compounds were retrieved using PubChem NCBI. Based on various research studies, four target proteins from NSCLC and sixteen bioactive compounds of Curculigoorchioides (Black musale) were selected. And their effect of bioactive compounds has been studied by means of in-silico approach and further the identified potential active compounds have been compared with control. This comparative in-silico study has predicted that the bioactive principle of Curculigoorchioides has better efficacy against cancer receptors and can considered as an effective alternative drug for cancer treatment. Concluding, the present study will be useful in future for designing novel therapeutic plant-based drug with higher efficacy for the treatment of lung cancer
An explorative study to assess the factors influencing well-being of patients with End Stage Renal Disease (ESRD) undergoing hemodialysis at dialysis units of selected hospitals of Bagalkot
Background: Kidneys are paired organ, occupying the lower position in the body and performing the upper most roles in homeostasis. Nowadays, chronic kidney disease (CKD) has been increasing due to various factors. Chronic Renal Failure is defined by the level of kidney function and the evidence of kidney damage. End Stage Renal Disease (ESRD) is a known increasing public health concern globally. The irreversible advanced CKD leads to End Stage Renal Disease (ESRD) where there is permanent loss of kidney function causing extreme mortality rates among this population1 Objective: Find the factors influencing wellbeing of patients with End Stage Renal Disease (ESRD) undergoing hemodialysis. Methods: This cross-sectional study included a sample of 100 patients with End Stage Renal Disease (ESRD) undergoing hemodialysis at Hanagal Shri Kumareshwar Hospital and Research Centre, Bagalkot and District Government Hospital, Bagalkot. Data were collected using self report method and Hospital’s records. Tools used for data collection were; socio-demographic questionnaire, Ryff’s Psychological Wellbeing scale and Centre for Epidemiologic Studies Depression Scale (CES-D Scale), Generalized Anxiety Disorder Scale – 7 (GAD-7). Multiple linear regression analysis was performed to find the significant predictors of Psychological Wellbeing. Results: A significant regression equation was found (F16, 99=4.5, R2=0.46, P=0.000). Social Support has positively predicted the Psychological Wellbeing of patients with End Stage Renal Disease (ESRD) undergoing hemodialysis. Depression and Anxiety was the strongest negative predictors of Psychological Wellbeing of patients with End Stage Renal Disease (ESRD) undergoing hemodialysis. Conclusion: Interventions aimed at management of depression, anxiety and strengthening of social support among patients with End Stage Renal Disease (ESRD) undergoing hemodialysis would result in enhancement their Psychological Wellbeing
Prevalence of Thyroid Eye Disease Among Thyroid Disorder Patients
Aim: To assess the prevalence of Thyroid Eye Disease among thyroid disorder patients. Introduction: Thyroid Eye Disease (TED) is a debilitating autoimmune disorder seen in hyperthyroid, hypothyroid and euthyroid patients. The global prevalence of TED is estimated to be 16 per 100,000 women and 2.9 per 100,000 men in the general population. Common symptoms include dry eyes, eyelid retraction, excessive watering, conjunctival redness and swelling, retro-orbital pain and blurred vision. This study aims to assess the prevalence of TED among dysthyroid patients attending Saveetha Medical College and Hospital, Chennai. Methodolody: The purpose of this study is to find the prevalence of TED among dysthyroid patients attending Saveetha Medical College and Hospital, Chennai during the months of July and August. A detailed history of each patient was taken after which a series of tests were conducted to identify and classify the severity of TED. This was done using NOSPECS (no signs, only signs, soft tissue involvement, proptosis, extraocular muscle involvement, corneal involvement, sight loss) classification. Schirmers test was performed to assess the prevalence of dry eyes among TED patients. Result: 122 patients consisting of 87 females and 35 males were included in this study. 43% (53 patients) were found to have Thyroid Eye Disease. There was no significant difference in prevalence between male and female subjects (43.6% and 42.8% respectively). The presence of TED was far greater in hyperthyroid than in hypothyroid patients. 44 out of 53 patients with TED were hyperthyroid (83%), 7 were hypothyroid (13.2%), and 2 patients were euthyroid (3.7%) . Schirmers test conducted on each patient revealed that 12% of the TED patients suffered from dry eyes. NCT test conducted to find the intraocular pressure in TED patients revealed no significant results. Conclusion: The high prevalence of TED seen in dysthyroid patients in this study calls for increased awareness regarding ocular manifestations in thyroid disorders. Patients should be encouraged to undergo regular checkups to ensure normal functioning of eyes and to prevent progression of the disease