University of Illinois at Chicago
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Deepening Our Engagement for Environmental Justice Participatory Research: Evidence-informed Insights from the Environmental Justice Community Scholars Fellowship
No full textThe Chicago Center for Health and the Environment (CACHET) Community Engagement Core (CEC) launched the Environmental Justice Community Scholars Fellowship (EJ Fellowship), an initiative that was co-developed with the Southeast Environmental Task Force (SETF) to build mutual capacity for CBPR. This fellowship brought together community organizers from five prominent EJ organizations: SETF, Neighbors for Environmental Justice (N4EJ), Pilsen Environmental Rights and Reform (PERRO), People for Community Recovery (PCR), and Alliance for the Southeast (ASE). Through this fellowship, the fellows and the CEC team implemented and evaluated a new, more collaborative engagement mechanism while aiming to build trust, nurture relationships, strengthen our collaborative work, and increase our collective capacity for CBPR. In this research brief, we share lessons learned from the evaluation activities.</p
Survey & Survey Data for Identifying Connections Between Evidence-Based Practice and the Maker Movement within Libraries: A Survey of Professionals from within Each Field - Gonzalez-Vicker
No full textIdentifying Connections Between Evidence-Based Practice and the Maker Movement within Libraries: A Survey of Professionals from within Each Field. Survey for Professionals in the Maker Movement and Evidence Based Practice.</p
Supplemental Data_<i>Lacticaseibacillus rhamnosus GG-</i>Driven Remodeling of Arginine Metabolism Mitigates Gut Barrier Dysfunction
No full textThese figures are supplemental materials.</p
Unexpected Deaths During a Real-World, Randomized Clinical Trial of Domiciliary Portable Air Cleaners in Patients With Moderate-to-Severe COPD
No full textNo description supplie
<i>Boiling Ballet: The Art of Dancing Bubbles</i>
No full textThe image presents a mirrored depiction of nucleate boiling from a heated wire submerged in a liquid pool. What appears as a simple process—bubbles forming and rising—is, in reality, a complex interplay of heat transfer, phase change, and fluid dynamics. Beneath its surface lies a thermodynamic landscape shaped by temperature gradients, nucleation site distributions, and the dynamic interactions of liquid and vapor. Bubble formation is not random but follows an intricate choreography that, without simulations, would remain obscured. These numerical models reveal the hidden physics governing nucleate boiling, enabling a deeper understanding and optimization of heat transfer. This image captures more than just a physical phenomenon—it represents a continuous exchange between energy and matter. As bubbles rise and dissipate, they leave behind transient traces, yet each reveals fundamental insights. Simulating boiling is essential for advancing thermal management technologies, from microelectronics cooling to nuclear reactors and space-based systems. Each simulation acts as a lens, making the invisible visible, bridging the gap between observation and innovation, and unlocking boiling’s full potential for efficient heat transfer.</p
<i>Our city is alive!</i>
No full textThe relationships among people in a city, along with its infrastructure, form the vibrant essence of urban life. People’s daily activities—commuting, socializing, and engaging in economic exchanges—are facilitated by interconnected systems such as transportation networks, electricity grids, communication technologies, and water distribution. These infrastructures act as both the stage and the enabler for human interactions, forming a complex web of activity that drives a city’s rhythm. My research focuses on studying these interactions and finding how human activity expresses itself in transportation networks and the electricity grid. We have observed that cities exhibit living-like behavior, working as organisms capable of metabolism, growth, resilience, and other properties typical of living entities. In this case, I am displaying the electricity usage in the Chicago region, where we have access to around 4 million smart-meter readings. Residential meters appear in a yellow shade, while commercial ones appear in blue. Can you also see the city beating?</p
<i>Journey Through Ice: Navigating </i><i>Air and </i><i>Dye Channels</i>
No full textMy research focuses on how contaminants in aqueous solutions affect the freezing process and ice-surface interactions. Pure ice tends to hold onto surfaces very strongly. Yet the smallest amounts of contaminants seem to cause the ice to slide off with the slightest applied force. Even more peculiar, there is a solute-enriched liquid layer that remains once the ice is pushed away, even for low weight-percentages of contaminants that should otherwise be frozen in the bulk ice. There must be some kind of mechanism that collects contaminants in the bulk ice and then channels them downwards towards the supercooled surface where it pools as an unfrozen aqueous liquid. To investigate these channels, we looked through a column of ice that was contaminated with dye. A camera with a macro lens moves its view at 20 microns per second through the ice, where we can see large air channels that formed from trapped air bubbles which diffused out during the freezing process. We also see thin strands and speckles of pink dye as the contaminants migrate through the ice and form small high-concentration pockets, which seem to burrow downwards towards the surface.</p
Advances in Discretized Network Flow with Application to Physical Synthesis
No full textNo description supplied</p
Discovery of New Antimicrobial Natural Products from Aquatic-Derived Bacteria
No full textFor many years, the discovery of antibiotics primarily relied on natural products. However, the rise of antimicrobial resistance has rendered many previously effective antibiotics useless. Moreover, efforts to find new antibiotics with novel mechanisms of action have largely been unsuccessful, as antimicrobial resistance is now developing at much higher rates than before. There is an urgent need for new natural products that can effectively target pathogenic bacteria using different mechanisms.
In this report, we present the discovery of a new natural product that selectively targets Streptococcus pyogenes, a known human pathogen. Although the exact mechanism of action is not fully understood, our research suggests that it specifically targets the Rgg2 quorum sensing system within S. pyogenes. Additionally, this compound is classified as an anti-persister molecule, which have gained attention in recent years for their ability to eradicate bacteria in dormant states—something that many current antibiotics struggle to achieve. Additionally, we present the screening of a natural product library new antimalarial agents, and report the discovery of a family of cyclic peptides as potential leads. Similar to bacteria, malaria has been reported to show significant resistance for several years now, indicating a pressing need for new drugs to combat this antimalarial resistance. These studies highlight the ongoing effectiveness of bioactivity-guided fractionation in discovering new drug leads
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