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    Executive Functioning and Sluggish Cognitive Tempo as Potential Mediators in the Relationship Between ADHD and Emotional Intelligence

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    Introduction. ADHD is a neurodevelopmental disorder characterized by executive functioning (EF) deficits and is associated with sluggish cognitive tempo (SCT) and reduced emotional intelligence (EI). The present study evaluated the mediating role of EF and SCT in the ADHD-EI relationship. Methods. Forty-nine college-aged participants completed self-report measures of ADHD symptoms, SCT, EF, and EI. Participants were remunerated $10 for their participation. Results. Regression analyses demonstrated that ADHD symptoms predicted EI, EF, and SCT (p’s \u3c 0.001). Contrary to hypothesis, neither EF nor SCT significantly mediated the relationship between ADHD and EI. Conclusion. Future research ought to aim to better understand the mechanisms accounting for the impairments associated with ADHD and EI, with a focus on emotion regulation. A better understanding of this complex relationship can lead to more effective intervention strategies for those with ADHD

    Mary Dean Lee Interviewed by Victoria Riva

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    Victoria Riva interviews Dr. Mary Dean Lee about growing up in Milledgeville Georgia. Listen to the podcast version here: YouTube https://youtu.be/a-VjHJIZ05A?si=sPAJgc_EMHEuE0TV Spotify https://spotifyanchor-web.app.link/e/nElxuuiTwNbhttps://kb.gcsu.edu/collectingthepast/1007/thumbnail.jp

    Sister Kathleen Feeley Interviewed by Audrey Burney

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    Audrey Burney interviews Sister Kathleen Feeley on advice for teachers and the impact of education. Listen to the podcast version here: YouTube https://youtu.be/VKstrVEkArU?si=8st7R4Vc-JBN7whG Spotify https://spotifyanchor-web.app.link/e/yx8pAZATwNbhttps://kb.gcsu.edu/collectingthepast/1012/thumbnail.jp

    Sandra Worsham Interviewed by Aggie Markwalter

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    Aggie Markwalter interviews Sandra Worsham on growing up in segregated Milledgeville and her extensive teaching background. Listen to the podcast version here: YouTube https://youtu.be/-fLgkc8sLYo Spotify https://spotifyanchor-web.app.link/e/RlAnPfsdpMbhttps://kb.gcsu.edu/collectingthepast/1011/thumbnail.jp

    DISTRIBUTION & ABUNDANCE OF HARVEYI CLADE PATHOGENS AND ENVIRONMENTAL FACTORS AS DRIVERS & PREDICTORS FOR THEIR CONCENTRATION DYNAMICS IN WATER, SEDIMENTS, & BIVALVES

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    Climate change and anthropogenic activities have significantly contributed to the global spread and persistence of pathogens. The Vibrio harveyi clade, a group of bacteria of particular concern for both human and wildlife health, is known for its environmental adaptability. As a result of climate-induced environmental changes, pathogens are now able to thrive in regions where they were previously absent. The Southeastern United States, with its favorable environmental conditions, serves as a key habitat for members of the V. harveyi clade. In this study, quantitative PCR (qPCR) assays were developed to detect specific species within the V. harveyi clade, facilitating the monitoring of their presence, abundance, and distribution in this region. Pathogens from this clade were detected at least once during the sampling period across a variety of environmental samples, including sediment, water, clams, and oysters. Overall, the results indicated that most species were present and most abundant in August. Additional findings suggest that the concentrations of V. parahaemolyticus and V. splendidus in water could serve as indicators of potential contamination or disease in mollusks. Notably, this study also identifies the presence of V. harveyi and V. campbellii in water and sediment samples—species that had not previously been reported in the Southeastern U.S. Furthermore, the study reveals that V. parahaemolyticus, V. harveyi, and V. campbellii are carriers of virulence genes (VGs), suggesting a risk for pathogenic outbreaks. Comparisons of environmental water parameters with species-specific copy numbers indicate that these parameters can potentially be used to predict the abundance of Harveyi clade pathogens in bivalves. Uneven distribution of these VG carriers also points to the possibility of specific hot spots for pathogenic bacteria. Together, these findings underscore the dynamic nature of pathogen distribution and the need for ongoing surveillance in regions at risk of new pathogen introductions. Continued research is crucial to understanding and mitigating the threats posed by these emerging pathogens

    Emily Davis Interviewed by Juliann Mackiewicz

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    Juliann Mackiewicz interviews Emily Davis, Baldwin County Commissioner for District 1, on her perspective growing up in Milledgeville and what it is like being a leader for your community. Listen to the podcast version here: YouTube https://youtu.be/DzZndl-jpeg Spotify https://spotifyanchor-web.app.link/e/xKYCdVATwNbhttps://kb.gcsu.edu/collectingthepast/1021/thumbnail.jp

    Nostalgic Neverland

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    Nostalgic Neverland is an original piece of writing that highlights the desire to stay a child forever. Along with the research part of the project is an original poem with a creative aspect to it. Simran Puri emphasizes on why Peter Pan inspires her and the poem is from the point of view of one who lives in Neverland and why they want to live there. Simran Puri wants her readers to resonate with her piece as most share the feeling of not wanting to grow up

    Effect of hypoxia on the structure of HIF1A mRNA 5ʹ untranslated region

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    The HIF1A gene is a transcriptional activator that regulates cellular responses to hypoxia by inducing transcription in many other genes, and plays an essential role in embryonic vascularization, tumor angiogenesis, and ischemic diseases. Overexpressed HIF1A gene has been found to be linked to many forms of carcinoma, breast, ovarian, and lung cancer. The gene is reported to exhibit internal ribosome entry site (IRES) activity. IRES activity uses regulatory structures located in the 5ʹ untranslated region of the mRNA allowing cap-independent translation. In the case of the HIF1A mRNA, IRES activity must be specifically activated under hypoxic stress. The mechanism of this process is unclear. To address this, we are interested in measuring changes in the structure and interactions of the regulatory region subjected to chemically-induced hypoxia. We have applied SHAPE-MaP to investigate the secondary structure of the regulatory region of the HIF1A mRNA in human cell lines to better understand the mechanisms of stress-induced initiation. We compare SHAPE data collected using gene-specific targeting of the HIF1A mRNA under (a) cell-free, (b) in-cell normoxic, and (c) in-cell hypoxic conditions. Our cell-free structure model reveals a highly structured 5ʹ UTR with multiple short hairpins motifs. Next, we closely compare live cell SHAPE data identifying regions that are affected by hypoxia. In addition to changes in SHAPE reactivity, we have detected changing patterns of protein interactions within the 5ʹ UTR under the varying conditions. Future directions include utilizing RNP-MaP, a UV-crosslinking strategy to examine specific protein-motif interactions affecting hypoxic translation, along with DMS-MaP to directly evaluate base-pairing with more specificity. Lastly, we identify orthogonal strategies to validate the HIF1A mRNA structure and interactions

    Gwynedd Webster Interviewed by Dawson Cowart

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    Dawson Cowart interviews Dr. Gwynedd Webster about moving to Milledgeville at a young age and exploring the O\u27Connor estate. Listen to the podcast version here: YouTube https://youtu.be/jgZjJsUjviI?si=nmRpB_VmtKUU5Wmb Spotify https://spotifyanchor-web.app.link/e/xj7pg0ATwNbhttps://kb.gcsu.edu/collectingthepast/1006/thumbnail.jp

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