Jurnal Universitas Abdurrab
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PENGARUH VARIASI LAMA PENYIMPANAN LARUTAN TURK MODIFIKASI AIR PERASAN JERUK NIPIS (Citrus Aurantifolia) TERHADAP HITUNG JUMLAH LEUKOSIT
Full text linkKetersediaan reagen Turk untuk pemeriksaan hitung jumlah leukosit secara manual yang biasa dilakukan oleh klinik sederhana atau klinik Puskesmas terpencil seringkali tidak tersedia, dapat terjadi karena kehabisan atau masa pakai yang sudah kadaluarsa. Sehingga banyak peneliti melakukan penelitian untuk mengatasi masalah tersebut dengan membuat larutan turk modifikasi salah satunya menggunakan air perasan jeruk nipis, namun reagensia alternatif tersebut belum diuji kualitasnya. Penelitian ini bertujuan untuk mengetahui bagaimana pengaruh lama penyimpanan larutan turk modifikasi air perasan jeruk nipis (Citrus aurantifolia) yang disimpan selama 1 hari, 7 hari dan 14 hari pada suhu ruang terhadap hitung jumlah leukosit. Merupakan penelitian eksperimen yaitu Post Test Only Control Group Design dengan variasi lama masa simpan 1, 7 dan 14 hari diulang sebanyak 12x dan dianalisis secara statistik. Rerata hitung jumlah leukosit untuk H1 sebesar 6.083 sel/mm3 H7 sebesar 7.612 sel/mm3 dan H14 sebesar 6.304 sel/mm3 serta kontrol sebesar 7.675 sel/mm3. Hasil uji ANOVA dan LSD menyatakan terdapat perbedaan bermakna hasil hitung jumlah leukosit H1 dan H14 dengan turk kontrol, sedangkan H7 tidak, akan tetapi interpretasi hasil hitung jumlah leukosit larutan Turk modifikasi jeruk nipis pada H1, H7 dan H14 masih menunjukkan kesesuaian dengan nilai rujukan yaitu 4.000-10.000 sel/mm3. The availability of Turk reagents for manual leukocyte count examinations, commonly performed by simple clinics or remote health centers, is often limited. This limitation can arise due to depletion or expiration of the reagents. Consequently, many researchers have sought to address this issue by developing modified Turk solutions, including those utilizing freshly squeezed lime juice, although the quality of these alternative reagents remains untested. This study aims to investigate the effects of storing modified Turk solutions with lime juice (Citrus aurantifolia) at room temperature for 1 day, 7 days, and 14 days on leukocyte count. This experimental research employed a Post Test Only Control Group Design, with variations in storage duration 1, 7, 14 days replicated 12 times and analyzed statistically. The mean leukocyte counts were 6.083 cells/mm3 at 1 day, 7.612 cells/mm3 at 7 days, and 6.304 cells/mm3 at 14 days, while the control exhibited a count of 7.675 cells/mm3. The results of the ANOVA and LSD tests indicated significant differences in the leukocyte counts between day 1 and day 14 with the control Turk, whereas day 7 did not show such differences, however, the interpretation of the leukocyte count results for the lime-modified Turk solution on days 1, 7, and 14 still indicated compliance with the reference values, i.e., 4,000-10,000 cells/mm3
UJI TOKSISITAS MERKURI (Hg) TERHADAP ORGAN GINJAL PADA TIKUS GALUR WISTAR (Rattus norvegicus) DENGAN PEMERIKSAAN UREUM DAN KREATININ SERTA HISTOPATOLOGI GINJAL
Full text linkHeavy metals have a bad effect for the body of animals and humans. The heavy metal that has the highest toxicity is mercury. Mercury (Hydrargyrum) is a chemical compound that is toxic to the body. Exposure to mercury that enters the body can cause acute and chronic poisoning effects as well as disturbances in various organ systems of the body. This study aims to determine the effect of subchronic toxicity on the kidneys by examining levels of urea, creatinine and histopathology of rat’s kidney organs.
In this preclinical study, the toxic compound used was mercury sulfate in powder form, then dissolved in aquabidest. This study used 12 male rats divided into 4 groups. The first group, the control group was given aquabidest solution, the 3 treatment groups were given mercury sulfate preparations at a dose of 10 mg/Kg BW, 20 mg/Kg BW, 30 mg/Kg BW. This research lasted for 4 weeks. Urea levels were checked three times, namely at week 0, week 2, and week 4 during the treatment period. At the end of the examination, the test animals were sacrificed for histopathological examination.
Administration of mercury sulfate with varying doses had an effect on the kidneys of rats as seen from the results of examination of unstable urea and creatinine levels, namely decreased and increased from normal limits, as well as histopathological examination of the kidneys which showed damage to the parts of the kidney. The conclusion of this study was that there was a toxic effect on the kidneys of white rats when exposed to mercury sulfate orally with graded doses for 4 weeks.Logam berat mempunyai efek yang tidak baik bagi tubuh hewan maupun manusia. Logam berat yang mempunyai toksisitas yang paling tinggi adalah logam berat merkuri. Merkuri (Hydrargyrum) merupakan salah satu senyawa kimia yang bersifat toksik bagi tubuh. Paparan merkuri yang masuk ke dalam tubuh dapat menimbulkan efek keracunan secara akut dan kronis serta gangguan pada berbagai sistem organ tubuh. Penelitian ini bertujuan untuk mengetahui efek toksisitas subkronik terhadap ginjal dengan pemeriksaan kadar ureum, kreatinin dan histopatologi organ ginjal tikus.
Pada penelitian praklinis ini senyawa toksik yang digunakan adalah Merkuri sulfat dalam bentuk serbuk, lalu dilarutkan kedalam akuabides. Penelitian ini menggunakan 12 ekor tikus jantan yang terbagi atas 4 kelompok. Kelompok pertama, kontrol diberi larutan akuabides, 3 kelompok perlakuan diberi sediaan Merkuri sulfat dengan dosis 10 mg/Kg BB, 20 mg/Kg BB, 30 mg/Kg BB. Penelitian ini berlangsung selama 4 minggu. Pemeriksaan kadar ureum dilakukan tiga kali yaitu pada minggu ke 0, minggu ke 2, dan minggu ke 4 selama masa perlakuan. Pada akhir pemeriksaan hewan uji dikorbankan untuk pemeriksaan histopatologi.
Pemberian merkuri sulfat dengan dosis bervariasi memberikan efek pada organ ginjal tikus yang dilihat dari hasil pemeriksaan kadar ureum dan kreatinin yang tidak stabil yaitu mengalami penurunan dan peningkatan dari batas normal, serta pemeriksaan histopatologi ginjal yang menunjukan adanya kerusakan pada bagian-bagian ginjal. Kesimpulan dari penelitian ini adalah terdapat efek toksik terhadap organ ginjal tikus putih pada pemaparan merkuri sulfat secara oral dengan dosis bertingkat selama 4 minggu
Kejenuhan dan Motivasi Belajar dengan Prestasi Akademik
Full text linkThis research aims to determine the relationship between learning boredom and learning motivation and academic achievement. The subjects of this research were 122 students from the class of 2020, Faculty of Psychology, UIN Raden Fatah Palembang. The number of subjects (112 women and 10 men) aged 20-23 years. Determining research subjects used the purposive sampling method. This research uses quantitative research methods with multiple regression techniques, as well as data collection using a learning boredom scale and a learning motivation scale. The results of the analysis show: 1) There is a relationship between learning boredom and learning motivation with academic achievement with a significance level of 0.047 (p<0.05). 2) There is no relationship between boredom and academic achievement with a significance level of 0.187 (p>0.05). 3) there is a relationship between learning motivation and academic achievement with a significance value of 0.032 (p<0.05). This research shows that learning boredom and learning motivation together have a relationship with academic achievement. Of the two independent variables, the learning boredom variable has no relationship with academic achievement. Meanwhile, the learning motivation variable is related to academic achievement. The implementation of this research is to produce innovative learning interventions and strategies that focus on increasing learning motivation and reducing learning boredom in students
Kualitas Tidur Mahasiswa Farmasi: Dampak Stres Akademik dan Efikasi Diri Saat Skripsi
Full text linkPharmacy students who are working on their thesis experience impacts on physical and psychological health such as experiencing poor sleep quality. Poor sleep quality can trigger academic stress and is supported by low self-efficacy. Therefore, the lower the quality of sleep possessed by students, the higher the level of academic stress in completing the thesis and vice versa. The purpose of this study was to examine the effect of academic stress and self-efficacy on sleep quality in 2020 Faculty of Pharmacy students at Muhammadiyah Purwokerto University who are doing thesis. This study uses quantitative methods with multiple linear regression tests. Respondents in this study totalled 101 Faculty of Pharmacy students. The measuring instruments used were sleep quality scale, academic stress scale, and self-efficacy scale. The results showed that academic stress and self-efficacy can simultaneously contribute an influence of 31.5% on sleep quality. Efforts are needed to improve sleep quality in order to minimize academic stress, such as practicing self-control to boost confidence in completing their thesis. 
Support Group dalam Menurunkan Tingkat Stres pada Caregiver Skizofrenia
Full text linkOne of the cases experienced by schizophrenia caregivers is stress. One intervention to reduce stress levels in schizophrenia caregivers is a support group. Support groups are carried out with peer groups who have relatively similar problems by sharing information about the problems experienced by schizophrenia caregivers. This research aims to reduce the level of stress felt by caregivers of schizophrenia, using a quasi-experiment and using 6 research subjects consisting of 5 female subjects and 1 male subject who have moderate to severe stress level scores. The data collection method was carried out using the Kingston Caregiver Stress Scale (KCSS) and analysis used the Repeated Measured Anova Test. The results of the support group intervention showed that caregivers experienced significant changes (p<0.05) in terms of reducing stress levels before and after providing support group therapy. This study has important implications for the implementation of support groups in reducing stress levels among caregivers of individuals with schizophrenia. It can be concluded that support groups are effective in lowering stress levels in schizophrenia caregivers
Evaluation of Antibiotic Use Based on ATC/DDD Criteria In Children with Pneumonia at RSI Siti Rahmah Padang
Full text linkPneumonia is inflammation or infection of the respiratory tract which causes pain and makes it difficult for sufferers to breathe because there is fluid in the form of pus in the alveoli sacs. Pneumonia is the highest cause of death in the world, especially in children under 5 years of age. Pneumonia caused by bacterial infections is treated using antibiotics. Antibiotics that are used inappropriately can cause bacterial resistance, resulting in worsening infections, an increase in infections, longer hospital stays, and increased health service costs. The aim of this research is to determine the quantitative evaluation of antibiotic use in pediatric patients with pneumonia at RSI Siti Rahmah Padang. This research is observational analytic with a retrospective design. The samples used in this study were pediatric pneumonia patients aged ≤18 years who cmet the inclusion criteria. Quantitative analysis was carried out by calculating the quantity of antibiotics used by pediatric pneumonia patients based on ATC/DDD criteria. The research results showed that the total DDD was 51.69 DDD/100 patient-days with the highest DDD value for the antibiotic ceftriaxone with a value of 19.44 DDD/100 patient-days.Pneumonia merupakan peradangan atau infeksi pada saluran pernapasan yang menyebabkan rasa nyeri dan membuat penderita kesulitan bernafas karena terdapat cairan berupa nanah pada kantung alveoli. Pneumonia merupakan penyebab kematian tertinggi di dunia khususnya pada usia anak-anak dibawah 5 tahun. Pneumonia yang disebabkan oleh infeksi bakteri diterapi menggunakan antibiotik. Antibiotik yang digunakan secara tidak tepat dapat menimbulkan resistensi bakteri yang mengakibatkan perparahan infeksi, terjadinya peningkatan infeksi, waktu rawat di rumah sakit yang semakin lama, dan meningkatnya biaya pelayanan kesehatan. Tujuan dari penelitian ini untuk mengetahui gambaran evaluasi penggunaan antibiotik secara kuantitatif pada pasien anak dengan pneumonia di RSI Siti Rahmah Padang. Penelitian ini bersifat observasional analitik dengan desain retrospektif. Sampel yang diunakan pada penelitian ini adalah pasien pneumonia anak dengan usia ≤18 tahun yang memenuhi kriteria inklusi. Analisis kuantitatif dilakukan dengan cara menghitung kuantitas pemakaian antibiotik yang digunakan pada pasien anak dengan pneumonia berdasarkan kriteria ATC/DDD. Hasil penelitian didapatkan Total DDD sebesar 51,69 DDD/100 patient-days dengan nilai DDD tertinggi pada antibiotik seftriakson dengan perolehan nilai 19,44 DDD/100 patient-days
IMPLEMENTATION OF AUTOMATIC PLANT SPRINKLERS USING SOIL MOISTURE SENSORS
Full text linkAutomatic plant sprinklers aim to replace manual work into automatic, as for the benefits obtained from this tool is that it can facilitate human work in watering onion plants. This tool uses a soil moisture sensor that functions as a soil moisture detector and sends commands to Arduino uno to turn on the relay so that the pump can turn on and splash water according to soil needs automatically. The design of this tool utilizes the nature of water, which is to fill empty space, and is always flat, this automatic plant sprinkler uses a water reservoir before water is splashed on the ground. Output holes applied to water reservoirs of the same height and diameter allow watering of the soil evenly. The results of the automatic plant sprinkler design test obtained after three tests, have a difference in the amount of water released from water hole one and water hole two, which ranges from 0-7%, which means it is still within the tolerance limit for onion plants, onion plants need soil moisture between 70-80%, which means it has a moisture tolerance between 10%
PELATIHAN REBRANDING DAN DIGITALISASI MARKETING BERBASIS WEBSITE PADA UMKM NYI LEHA BATIK
Full text linkIntroduction The problem faced by 'Nyi Leha Batik' MSMEs is that product branding is still low. With its main product batik, MSME 'Nyi Leha Batik' is trying hard to compete with almost similar products on the market. Including marketing access too, is one of the problems faced by 'Nyi Leha Batik' MSMEs. Purpose In order to be able to compete with other products, 'Nyi Leha Batik' MSMEs must move up in class. Convenience.Method The method used is carrying out website-based rebranding and digital marketing training.Results The results of this activity include increasing knowledge of 'Nyi Leha Batik' MSME managers regarding rebranding and website-based digital marketing..Recommendationgovernment and private participation so that micro and small businesses can continue to develop. Furthermore, easy access to funding is very necessary for the development of micro and small businessesPermasalahan yang dihadapi UMKM ‘Nyi Leha Batik’ yakni masih rendahnya branding produk. Dengan produk utama batik, UMKM ‘Nyi Leha Batik’ berusaha keras untuk bersaing dengan produk yang hampir serupa di pasaran. Termasuk akses pemasaran juga, menjadi salah satu masalah yang dihadapi UMKM ‘Nyi Leha Batik.Tujuan: .Agar bisa bersaing dengan produk lainya, maka UMKM ‘Nyi Leha Batik’ harus naik kelas. Kemudahan .Metode: Metode yang digunakan yakni melaksanakan pelatihan rebranding dan digital marketing berbasis website.Hasil: Hasil kegiatan ini diantaranya, meningkatnya pengetahuan pengelola UMKM ‘Nyi Leha Batik’ tentang rebranding dan digital marketing berbasis website.Rekomindasi: partisipasi pemerintah maupun swasta agar usaha mikro kecil dapat terus berkembang. Lebih lanjut, adanya kemudahan akses pendanaan pun sangat dibutuhkan untuk pengembangan usaha mikro kecil
 
PEMBERDAYAAN ANGGOTA PKK DALAM PENGELOLAAN OBAT DAN BEYOND USE DATE (BUD) DI KELURAHAN KAUMAN KOTA MALANG
Full text linkStorage of medicines is an important aspect in ensuring the effectiveness of the medicine when consumed. Some medicines need to be stored in a special place such as a refrigerator. The length of time medicines are stored generally follows the expiry date (ED), which is the time limit for use of the medicine after it is produced by the pharmaceutical factory before the primary packaging is opened. If the primary packaging has been opened, it follows the beyond use date (BUD). The public sometimes pays little attention to where a drug is stored and how long it is stored. The aim of the activity is to provide knowledge for PKK members in Kauman Village, Malang City about storing medicines, especially those that require special storage and Beyond Use Date (BUD) of medicines. The method used is providing information and knowledge regarding drug management in the household, especially regarding drug storage and Beyond Use Date (BUD) with a socialization method implemented 3 (three) times. The results of the socialization activities from the first to the third stages ran smoothly. From the evaluation results, it is known that the knowledge of the 20 PKK members of Kauman Village, Malang City, who were involved, experienced an increase, where from the pre-test the average score was 6.60, while the post-test results averaged a score of 8.15. The percentage increase in knowledge based on the average post-test score was 23.4%. For this reason, when providing drug services, we are expected to always provide education regarding storage and how long the drug can be stored.Penyimpanan obat merupakan salah satu aspek penting dalam menjamin efektivitas obat tersebut ketika dikonsumsi. Beberapa obat perlu disimpan pada tempat khusus seperti lemari pendingin. Lama obat disimpan umumnya mengikuti expired date (ED) yaitu batas waktu penggunaan obat setelah diproduksi oleh pabrik farmasi sebelum dibuka kemasan primernya. Apabila kemasan primer telah dibuka maka mengikuti beyond use date (BUD). Tempat penyimpanan dan berapa lama suatu obat disimpan terkadang kurang diperhatikan oleh masyarakat. Tujuan kegiatan adalah memberikan pengetahuan bagi para anggota PKK di Kelurahan Kauman Kota Malang tentang penyimpanan obat-obatan terutama yang membutuhkan penyimpanan khusus dan Beyond Use Date (BUD) obat. Metode yang digunakan yaitu pemberian informasi dan pengetahuan mengenai pengelolaan obat di rumah tangga khususnya terkait penyimpanan obat dan Beyond Use Date (BUD) dengan metode sosialisasi sebanyak 3 (tiga) kali implementasi. Hasil kegiatan sosialisasi dari tahap pertama sampai ketiga berjalan dengan lancar. Dari hasil evaluasi diketahui pengetahuan anggota PKK Kelurahan Kauman Kota Malang yang terlibat sejumlah 20 orang mengalami peningkatan dimana dari pre-test diperoleh skor rata-rata adalah 6,60 sedangkan hasil post-test rata-rata skor adalah 8,15. Persentase peningkatan pengetahuan berdasarkan rata-rata skor post-test adalah sebesar 23,4%. Untuk itu dalam melakukan pelayanan obat diharapkan untuk selalu memberikan edukasi terkait penyimpanan dan lama obat tersebut boleh disimpan
PENINGKATAN LITERASI HALAL JAMA’AH PENGAJIAN MAJELIS TA’LIM NURUL IMAN GEJIKAN, GAGAK SIPAT, NGEMPLAK, KAB. BOYOLALI
Full text linkThe Nurul Iman Ta'lim Majlis congregation is a community that has positive activities in its daily life and also consists of various types of professions within it. Routine activities, including the promotion of halal literacy, are carried out every Friday night. The importance of socializing halal literacy is because several business actors on the MSME scale need to carry out self-declaration of halal certification, which the government has provided. Lack of literacy causes a lack of public access and knowledge, so direct outreach is needed from experts, namely the Center for Halal Studies (PSH). The method used was training and outreach related to halal literacy and obtaining halal certification, which was carried out in Gejikan village, Gagaksipat, Boyolali, on June 22 2023. The results of the service carried out by the Sharia Faculty team at UIN Raden Mas Said Surakarta were attended by 50 congregations who participated in the outreach and were enthusiastic about the material as evidenced by several questions. There are 5 out of 50 congregations own MSME products and join in the halal certification process through a self-declaration process accompanied by PSH. Knowledge and socialization are delivered well, increasing scientific abilities and practices related to halal.Jamaah Majelis Ta’lim Nurul Iman merupakan salah satu komunitas masyarakat yang memiliki kegiatan positif dalam keseharian dan juga terdiri dari berbagai jenis profesi. Kegiatan rutin dilakukan setiap malam Jumat termasuk adanya sosialisasi adanya literasi halal. Pentingnya sosialisasi literasi halal dikarenakan terdapat beberapa yang merupakan para pelaku usaha dengan skala UMKM untuk melakukan sertifikasi halal secara self-declare yang sudah disediakan oleh pemerintah. Kurangnya literasi menyebabkan kurangnya akses dan pengetahuan masyarakat sehingga diperlukan sosialisasi langsung dari ahlinya yakni Pusat Studi Halal (PSH). Metode yang digunakan yakni adanya pelatihan dan sosisalisasi terkait literasi halal dan proses mendapatkan sertifikasi halal yang dilaksanakan di desa Gejikan, Gagaksipat, Boyolali pada 22 Juni 2023. Hasil dari pengabdian dilakukan olehtim Fakultas Syariah UIN Raden Mas Said Surakarta ini diikuti oleh 50 jamaah yang mengikuti sosialisasi dan antusias dengan materi tersebut terbukti dengan adanya beberapa pertanyaan. Terdapat 5 dari 50 jamaah yang memiliki produk UMKM dan ikut melakukan proses sertifikasi halal melalui proses self-declare yang didampingi oleh PSH. Penyampaian pengetahuan dan sosialisasi dilakukan dengan baik, meningkatnya kemampuan keilmuan dan prkatik terkait halal