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Molecular Dynamics Simulations of Curcuminato-(η⁶-p-cymene)ruthenium(II) Docking in the Minor Groove of DNA: Evaluating Equilibrium Stability via 2D RMSD Analysis
Molecular dynamics simulations were conducted to study the interaction between Curcuminato-(η⁶-p-cymene)ruthenium(II) and DNA, focusing on minor groove binding at the N7 position of guanine. The system equilibrated at approximately 170 picoseconds, with the lowest potential energy configuration of -36.271 kcal/mol observed at 251 K at 464 picoseconds. The simulated Ru-N7 distance was 8.55 Å, contrasting with the literature-reported value of 2.824 Å, highlighting the influence observed over time evolution of the system on key interaction. The root-mean-square deviation (RMSD) matrix stabilized at approximately 2.30 Å at equilibrium, reflecting the conformational stability of the system. Temporal profiles of temperature, potential energy, and total energy further characterized the equilibration and stability processes. These findings advance the understanding of ruthenium-curcumin complexes in biomolecular systems and their potential therapeutic applications
Performance of Quasi-isotropic GF/PET Laminates in Impact and compression after Impact Loading
The impact resistance and residual compression strength of two types of glass fiber/ polyethylene terephthalate composites are investigated in this research project. The first materials are glass fiber/ polyethylene terephthalate glycol (GF/PRTG) and the second material is glass fiber/ amorphous polyethylene terephthalate (GF/PETa). Both matrix materials are ductile thermoplastic polymers. The ductility of the matrix is expected to improve the impact resistance of the composites. The advantage of the first material is higher ductility and improved fire resistance, and the advantage of the second material is high bonding strength with the reinforcing fiber glass. Both matrixes and low cost engineered polymers.
Quasi-isotropic samples of both materials were fabricated and tested under impact and compression after impact. The obtained data is being analyzed and results of the research, including comparison with the performance of similar continuous fiber reinforced thermoplastic composites, are presented in this poster
Student Senate Meeting Minutes October 1, 2025
This document is the official Winona State University Student Senate Minutes for October 1, 2025
What is the Relationship Between Success on the Limited X-Ray Machine Operator Exam and the First-Attempt Pass Rate on the National Registry Exam Among Radiologic Technology Students in Minnesota?
This quantitative correlational study examined the relationship between success on the Limited X-Ray Machine Operator (LXMO) exam and first-attempt pass rates on the national registry exam among radiologic technology students in Minnesota. The radiologic technology field faces significant challenges, including a 14.9% national attrition rate, workforce shortages, and limited availability of clinical sites. This research explored whether LXMO certification could serve as an innovative approach to address these interrelated issues. Data were collected from the Minnesota Department of Health and the American Registry of Radiologic Technologists, spanning 2000-2024, and identified n=24 students who had completed both exams. Results revealed that LXMO-certified students had a 70.8% first-time pass rate on the national registry exam, which is lower than the national average (85.2%) and the Minnesota average (83%), failing to support the hypothesis that LXMO certification would improve registry exam performance. The study was analyzed within the framework of Cognitive Load Theory, suggesting that LXMO exam preparation may create mental frameworks that are too narrow for the comprehensive registry exam. Despite these findings, the research highlights the potential practical benefits of LXMO certification, including increased clinical independence, reduced supervision requirements, and mitigation of workforce shortages. The small sample size (24 participants) and inability to account for factors such as timing between exams and student characteristics limit the generalizability of findings. Future research should expand to larger sample sizes across multiple states, employ longitudinal designs to examine optimal timing between exams, and incorporate mixed methods to better understand students\u27 experiences with both certifications
Professor Gertrude Staples of Winona Normal School
Gertrude Staples, English instructor at Winona Normal School from 1884-1889https://openriver.winona.edu/wsuphotographs-minnesotareflections/1016/thumbnail.jp
Frances Armstrong
Frances Armstrong, 1878 graduate of Winona Normal School. Frances Armstrong was one of the educators sent to Argentina in 1883 to establish that country\u27s school system.https://openriver.winona.edu/wsuphotographs-minnesotareflections/1019/thumbnail.jp
Principal William Phelps of Winona Normal School
William Phelps, principal of Winona Normal School from 1864-1876https://openriver.winona.edu/wsuphotographs-minnesotareflections/1055/thumbnail.jp
The Back of Postcard MHS01763
The back of postcard MHS01763https://openriver.winona.edu/wsuphotographs-minnesotareflections/1091/thumbnail.jp
Home Economics Class, Winona State Normal School, Winona, Minnesota
View of a Home ecomonics class at Winona State Normal School.https://openriver.winona.edu/wsuphotographs-minnesotareflections/1197/thumbnail.jp
Winona State Portrait of Dr. Lyman Denton, Winona State Normal School, Winona, Minnesota
Portrait of Dr. Lyman Denton.https://openriver.winona.edu/wsuphotographs-minnesotareflections/1221/thumbnail.jp