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Integrating compassion and policy: Highlights from IAHPC Advocacy, 2025
No full textIn 2025, the International Association for Hospice and Palliative Care (IAHPC) advanced advocacy for palliative care as an ethical, clinical, and human rights imperative. As a non-state actor in official relations with the World Health Organization (WHO), the association worked across policy, faith, and professional domains to integrate palliative care into universal health coverage frameworks. This report summarizes IAHPC’s global activities from February to November 2025, including engagement at the 78th World Health Assembly (WHA), collaboration with WHO and the International Narcotics Control Board (INCB), the launch of the Leadership and Advocacy Development (LEAD2) program, and new interfaith and educational initiatives
Dietary models in the treatment of polycystic ovary syndrome
No full textZespół policystycznych jajników (PCOS, polycystic ovary syndrome) to schorzenie objawiające się zaburzeniami owulacji, płodności oraz hiperandrogenizmem. Często towarzyszą mu insulinooporność, otyłość, zaburzenia lipidowe i trądzik. Wyróżnia się trzy fenotypy PCOS: metaboliczny, hiperandrogeniczny oraz reprodukcyjny. Odpowiednio dobrany model żywienia, wsparty celowaną suplementacją, może przyczyniać się do normalizacji masy ciała oraz poprawy parametrów metabolicznych i hormonalnych. Wśród dostępnych strategii dietetycznych najwięcej dowodów naukowych potwierdza skuteczność diety śródziemnomorskiej oraz DASH. Oba modele żywieniowe koncentrują się na wysokiej podaży warzyw i owoców bogatych w antyoksydanty, zdrowych tłuszczów, chudego białka oraz produktów pełnoziarnistych, co sprzyja stabilizacji gospodarki hormonalnej i metabolicznej. W świetle aktualnych wytycznych Polskiego Towarzystwa Ginekologicznego (PTG) inozytol stanowi jeden z rekomendowanych składników wspomagających terapię PCOS. Coraz więcej dowodów naukowych wskazuje również na korzystne działanie witaminy D oraz kwasów omega-3, które cechują się zarówno skutecznością, jak i wysokim profilem bezpieczeństwa. Ponadto wyniki badań sugerują, że berberyna oraz magnez mogą wykazywać pozytywny wpływ na przebieg PCOS, jednak brakuje oficjalnych zaleceń w tym zakresie. Celem pracy jest omówienie wybranych modeli żywieniowych oraz suplementów diety wspomagających leczenie PCOS.Polycystic ovary syndrome (PCOS) is a condition characterized by ovulatory dysfunction, infertility, and hyperandrogenism. It is often accompanied by insulin resistance, obesity, lipid disorders, and acne. Three phenotypes of PCOS are distinguished: metabolic, hyperandrogenic, and reproductive. A properly tailored dietary model, supported by targeted supplementation, may contribute to body weight normalization and improvement in metabolic and hormonal parameters. Among the available dietary strategies, the Mediterranean diet and the DASH have the strongest scientific evidence supporting their effectiveness. Both dietary models focus on a high intake of antioxidant- rich vegetables and fruits, healthy fats, lean protein, and whole grain products, which promote the stabilization of hormonal and metabolic balance. According to the current guidelines of the Polish Gynecological Society (PTG), inositol is one of the recommended components supporting PCOS therapy. Increasing scientific evidence also suggests the beneficial effects of vitamin D and omega-3 fatty acids, which are both effective and have a high safety profile. Additionally, research findings indicate that berberine and magnesium may have a positive impact on the course of PCOS; however, there are no official recommendations in this regard. Aim of this study is to discuss selected dietary models and dietary supplements that support the treatment of PCOS
Disabling diseases and disabilities in professional divers from the region of Murcia (Spain)
No full textBackground: Professional diving is an activity that is carried out more and more frequently, due to the great professional opportunities it offers. It is a job with high responsibility and a lot of risk, involving low temperatures, adverse weather conditions, and high pressures, which requires the diver to be in optimal conditions. The general objective of this research work is to analyze disabling diseases and disabilities in professional divers in the Region of Murcia.
Material and methods: A descriptive and cross-sectional observational study, type of case series, has been carried out to analyze the causes and factors of the disabilities that occurred in 169 professional divers in the region of Murcia (Spain) from 2014 to 2020.
Results: The accumulated incidence of disability in seven years, with 39 cases, is 230.7 subjects per 1,000 divers, much higher than that of the rest of the maritime workers, which turns out to be 130.1/1000 in the same period of time. The average age is 33.7 ± 7.2 years, and the professional experience is 9.6 ± 6.1 years. Occupational diseases and work accidents were responsible for 15 (38.55%) cases. Otorhinolaryngologic (33.3%), musculoskeletal (25.6%), and psychiatric (10.2%) pathologies are the three most common causes.
Conclusions: Perfect physical condition, health and, especially, age in professional diving are a limitation, the latter being a risk indicator, so it is essential that the professional is in optimal physical condition and is aware of the limitations to carry out said professional activity, due to the great adversity it entails in being able to carry out it throughout one’s entire active working life
Kardiologia interwencyjna w erze sztucznej inteligencji
No full textRecently, one of the most rapidly developing areas of medicine has been artificial intelligence (AI), defined as the ability of computer systems to perform tasks that require cognitive processes characteristic of the human mind. Its application goes beyond theoretical concepts and provides real support in everyday clinical practice. Currently, in interventional cardiology, AI-based algorithms support the identification of pathologies and risk stratification in areas including valvular disease, coronary artery disease, atrial fibrillation, aortic aneurysms and acute coronary syndromes. As a result, cardiac care becomes more precise, tailored to individual patient needs and proactive, focusing on preventing complications and improving clinical outcomes. Simultaneously, adequately prepared medical personnel for the implementation of new technologies remains a significant challenge. A lack of awareness of the limitations and principles of safe AI implementation can limit its effective use in everyday clinical practice. Thus, education and adaptation of healthcare systems are essential to utilize the potential of AI in interventional cardiology fully.Sztuczna inteligencja (AI, artificial intelligence), definiowana jako zdolność systemów komputerowych do wykonywania zadań wymagających procesów poznawczych typowych dla ludzkiego umysłu, stała się w ostatnich latach jednym z najbardziej dynamicznie rozwijających się narzędzi w obszarze medycyny. Jej zastosowania wykraczają poza koncepcje teoretyczne i coraz częściej stanowią realne wsparcie w codziennej praktyce klinicznej. Aktualnie w kardiologii interwencyjnej algorytmy oparte na AI wspierają identyfikację patologii oraz stratyfikację ryzyka w takich obszarach jak: wady zastawkowe, choroba wieńcowa, migotanie przedsionków, tętniaki aorty czy ostre zespoły wieńcowe. W efekcie, opieka kardiologiczna staje się bardziej precyzyjna, proaktywna i w większym stopniu ukierunkowana na indywidualne potrzeby pacjenta — koncentruje się na zapobieganiu powikłaniom i poprawie wyników klinicznych. Jednocześnie istotnym wyzwaniem pozostaje odpowiednie przygotowanie personelu medycznego do wdrażania nowych technologii. Brak świadomości ograniczeń oraz zasad bezpiecznej implementacji AI może ograniczać jej skuteczne zastosowanie w codziennej praktyce klinicznej. Edukacja kadry oraz adaptacja systemów opieki zdrowotnej do nadchodzących zmian są kluczowe, aby w pełni wykorzystać potencjał AI w kardiologii interwencyjnej
Stany zagrożenia życia w toczniu rumieniowatym ukladowym
No full textSystemic lupus erythematosus is one of the prototypical connective tissue diseases with a poor prognosis. The disease can involve nearly all vital organs and systems. This paper reviews the organ manifestations of lupus that pose a real, life-threatening risk to affected patients.Toczeń rumieniowaty układowy należy do prototypowych chorób tkanki łącznej, o złym rokowaniu. W przebiegu choroby dochodzi do zajęcia niemalże wszystkich życiowo ważnych narządów i układów. W pracy dokonano przeglądy narządowych manifestacji tocznia stanowiących realne zagrożenia dla życia dotkniętych chorobą pacjentó
How to prevent and treat cardiovascular diseases in people living with breast cancer? Recent advances
No full textBreast cancer treatment has improved in recent decades, meaning that, in more economically developed countries, people living with breast cancer (PLBC) and breast cancer survivors (BCS) face a decreasing mortality rate from breast cancer itself. However, it is becoming increasingly apparent that PLBC and BCS have an increased risk of cardiovascular disease (CVD) compared to the general population, and in some PLBC, CVD mortality risk is greater than the breast cancer mortality risk. This is due to the shared mechanisms between breast cancer and CVD as well as cancer treatment-related cardiovascular toxicity (CTR-CVT). CTR-CVT in breast cancer encompasses a wide range of cardiovascular disease and can arise from both traditional anticancer therapies, such as anthracyclines, and newer agents, such as olaparib and palbociclib. In this review, we outline the problem of CVD in PLBC and BCS as well as the spectrum of CTR-CVT in breast cancer. We consider the emerging CTR-CVT primary prevention strategies in PLBC and novel markers of subclinical CTR-CVT. Lastly, we consider late CTR-CVT and the importance of long-term surveillance in this cohort
Komentarz do artykułu „Aspekty prawne i medyczne w odniesieniu do nieprawidłowości w postępowaniu diagnostyczno-terapeutycznym w przypadku ciąży pozamacicznej — opis przypadku”
No full textPrognostic value of the platelet-to-lymphocyte ratio for outcomes after out-of-hospital cardiac arrest
No full text„Ćwierćwiecze onkologii akademickiej w Lublinie” pod redakcją prof. Wojciecha Polkowskiego i dr. Tomasza Orłowskiego
No full textDistinct local brain atrophy pattern in clinically stable multiple sclerosis patients during the peri-pregnancy period: A follow-up study
No full textAim of the study. The objective of the study was to evaluate local brain volume in short and long follow-up periods in the same group of women with multiple sclerosis (MS), which was evaluated in our in previous study during the peri-pregnancy period (PPP).
Clinical rationale for the study. In our previous study we observed a significant reduction in thalamus volume (TV) during PPP in clinically stable patients with MS. In this follow-up study we determined whether the observed regional brain volume change during the PPP was also a long-term effect.
Materials and methods. We included 11 patients with MS and clinical and magnetic resonance imaging (MRI) data, obtained at 4 time points: time point 1 (TP1) up to 6 months before pregnancy; time point 2 (TP2) up to 6 months after delivery; time point 3 (TP3) > 12 months after TP2, “short-term follow-up”; time point 4 (TP4) > 24 months after TP2, “long follow-up”. MRI analysis including assessment of T2 lesion volume, T2LV; T1 lesion volume, T1LV; number of gadolinium-enhanced lesions, T1GD+; TV and corpus callosum volume (CCV) was performed at each time points. Results. At TP3, CCV was significantly lower compared with TP2 (p = 0.02). We also found that T1LV significantly increased at TP3 compared with TP2 (p = 0.02). In the short follow-up we observed a slightly greater change in CCV than in the primary study (p = 0.06). At TP4, CCV was significantly lower and T1LV was significantly higher compared with TP2 (p = 0.02, p = 0.02, respectively). We observed a significant increase of T1LV at all time points beginning with TP1.
Conclusion. Our study demonstrates that in clinically stable patients with multiple sclerosis in the peri-pregnancy period regional brain atrophy and burden of focal lesions progress in the short and long term despite re-initiating the same therapy. These observations suggest that the protective effects of pregnancy on the pathological processes in MS are limited.
Clinical implications. Our findings provide relevant clinical information. Local brain atrophy and increase of focal lesion burden should be considered for decision-making in the treatment of women with MS early in the postpartum period to prevent disease progression