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    Analysis of phacoemulsification surgery on quantitative variation of anterior chamber using Sirius tomogram in patients of North India

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    BACKGROUND: The purpose of this study was to quantify the alterations in anterior chamber angle (ACA) parameters following phacoemulsification surgery. We also aim to assess changes in intraocular pressure (IOP) by comparing preoperative and postoperative measurements. Furthermore, the study explores potential associations between changes in ACA parameters and clinical outcomes, including IOP control. MATERIAL AND METHODS: A prospective observational study of ACA parameters among patients undergoing phacoemulsification surgery in North India. All patients were examined preoperatively and 1 month postoperatively using the Sirius tomographer to study ACA, anterior chamber depth (ACD), anterior chamber volume (ACV), central corneal thickness (CCT), and corneal volume (CV). IOP was assessed using the Goldmann applanation tonometer. This clinical study included 40 eyes of 40 patients. RESULTS: There is a statistically significant increase in mean ACA measurement from 47.27 ± 6.54° to 56.74 ± 4.72°, mean ACD from 2.76 ± 0.39 mm to 3.45 ± 0.39 mm, mean ACV from 160.47 ± 24.41 mm3 to 196.63 ± 23.63 mm3, mean CV from 52.92 ± 3.22 mm3 to 54.23 ± 2.86 mm3. The mean IOP measurement decreased from 17.03 ± 2.08 mm Hg preoperatively to 15.58 ± 2.92 mm Hg postoperatively and is statistically significant (p ≤ 0.001). CONCLUSION: The study provides valuable insights into quantifying ACA in the North Indian population using Scheimpflug corneal tomography. It shows a significant increase in ACA, ACD, ACV, and CV and a significant decrease in IOP following uneventful cataract surgery. These findings have implications for managing cataracts associated with glaucoma and other ocular conditions

    Primary leiomyosarcoma of the right ventricle with metastases in a young female

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    Cardiac computed tomography for planning and guidance of coronary revascularization: An expert position of the Association of Cardiovascular Interventions of the Polish Cardiac Society

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    Coronary computed tomography angiography (CCTA) is a guideline-recommended imaging modality for detecting coronary artery stenoses and risk stratification in patients with low-to-intermediate pretest likelihood of coronary artery disease (CAD). Significantly, the steady advances in CT technology, extending its wider adoption to more challenging patient populations, coincided with new data from clinical trials supporting the role of CCTA for preprocedural planning and periprocedural guidance of coronary interventions. The abundance of anatomic, morphological, and physiological information incorporated from CCTA is uniquely suited to streamlining CAD diagnosis and treatment. Specifically, the additive value of CCTA over invasive angiography can be characterized as follows: 1) detailed evaluation of plaque volume and composition including detection of high-risk plaques; 2) improved referrals to coronary revascularization (including the preferred mode of intervention) by means of CCTA-derived fractional flow reserve and/or CT myocardial perfusion imaging; 3) preprocedural planning and periprocedural guidance in complex CAD (including chronic total occlusions, bifurcations, calcified lesions, bypass grafts); 4) selection of stent size based on anatomic (qualitative CT plaque analysis) and physiological (CT-fractional flow reserve virtual stenting algorithms) information; and 5) identification of the coronary sites suitable for surgical anastomosis. The aim of the current expert consensus document is to highlight the key advantages of CCTA in the planning and intraprocedural guidance of coronary revascularization interventions, and to provide specific recommendations regarding its practical use by interventional cardiologists

    A brief history and clinical use of robotic procedures in the cardiovascular system

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    Robotic-assisted percutaneous coronary intervention (r-PCI) exemplifies the advancement of interventional cardiology by integrating robotics to improve procedural control, operator safety, and potentially patient outcomes. This is a brief history of the development of r-PCI and robotics in cardiac surgery. r-PCI is currently more common in elective PCI cases, where time and precision are prioritized, however, the progress that has been made in surgical robotics allows us to believe in rapid progress of robots dedicated to complex coronary lesions treatment. The successful remote PCI in China highlights the potential of robotic systems to revolutionize interventional cardiology by offering both precision and remote accessibility, particularly in regions with limited access to specialized cardiovascular care

    Effectiveness and safety of direct oral anticoagulants combined with antiplatelet agents in patients with acute coronary syndrome following percutaneous coronary intervention, with or without atrial fibrillation: A systematic review and network meta-analysis

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    Background: The use of direct oral anticoagulants (DOACs) in patients with acute coronary syndrome (ACS) is still controversial.Aims: To assess the safety and effectiveness of DOACs combined with antiplatelet agents in patients with acute coronary syndrome after percutaneous coronary intervention (PCI).Material and methods: A systematic search was performed across PubMed, Embase, Cochrane Library, and Web of Science, to identify randomized controlled trials focusing on DOACs in ACS patients or those receiving PCI treatment. The search was completed by May 18, 2024. Quality assessment of the included studies was conducted utilizing the risk of bias tool. Subsequently, data analysis was conducted via R software.Results: In total, 7 articles were included, encompassing 23 301 patients. The DOACs examined included rivaroxaban, dabigatran, and apixaban. The results indicated that in comparison to dual antiplatelet therapy (DAPT) with rivaroxaban, apixaban combined with single antiplatelet therapy (SAPT) reduced stroke risk (odds ratio [OR], 0.48; 95% credible interval [CrI], 0.25–0.91). In comparison to rivaroxaban/SAPT, the risk of stroke was notably elevated with the rivaroxaban/DAPT regimen (OR, 2.27; 95% CrI, 1.01–5.32). Compared to rivaroxaban/DAPT, dabigatran/SAPT had a greater risk of myocardial infarction (MI) (OR, 1.73; 95% CrI, 1.16–2.59). Compared to standard treatment, rivaroxaban/DAPT evidently decreased MI risk (OR, 0.79; 95% CrI, 0.66–0.95). No remarkable differences were found in the risk of bleeding events between the DOACs combined with antiplatelet and standard treatment groups.Conclusion: Our meta-analysis suggests that the dual pathway inhibition antithrombotic regimen does not markedly increase the bleeding risk compared with standard treatments in ACS patients following PCI. Furthermore, compared to traditional antithrombotic regimens, the combination of rivaroxaban with DAPT potentially reduces the risk of MI

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