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Aneurysmatic Subdural Haemorrhage: Brief Review
Get PDFAcute subdural hemorrhage caused by a ruptured intracranial aneurysm is a well-known association but usually linked to dismal outcome. We briefly reviewed the clinical and imaging features, surgical management and outcome of 45 patients with subdural bleeding related to intracranial aneurysm. Forty-two reports were encountered in the literature between 1981-2015 and three additional patients were identified in the author personal archives. A total of three patients had bilateral acute subdural hemorrhage, and the epidural hematoma was not present in any of the 45 reports. Coma was identified in 32/45 (71%) patients at admission. Only seven of 45 cases reported were managed by endovascular approach. A good clinical outcome was observed in 23/45 (51%) and early mortality occurred in 10/45 (22%) of the patients analysed. Neurosurgical management has evolved tremendously in recent years leading to more comprehensive understanding about this association. Factors leading to natural history, mechanisms, imaging aspects and improvement of clinical results of aneurysmatic subdural bleeding merit further studies
Personality Type A or Personality Type D, Which is a Strong Predictor of Coronary Heart Disease?
Get PDFConsidering the increasing incidence and prevalence of coronary heart disease and the increasing emphasis of health researchers on the association and relationship of psychosocial factors with the occurrence and persistence of cardiovascular disease, the need to identify the desired factors and determine each of the personality and psychological factors. The effect is felt more than ever in patients who are also the target of the present study. The main purpose of this study was to determine the predictors of coronary heart disease based on personality types. Among cardiovascular patients, men and women aged 25-60 years in Shahid Madani and 29 Bahman hospitals in Tabriz, who were admitted to surgical wards for coronary angiography in 2015, 50 people were selected who met the inclusion criteria. Also, 50 patients were selected from the patients' companions and answered the questionnaires of Denollet type D personality and Ratus personality pattern questionnaire. Findings showed that the variables of negative emotions, social inhibition of the personality type D subscale were predictors of coronary heart disease. But the role of personality type A in predicting coronary heart disease is not significant. Social inhibition was also the strongest predictor of coronary heart disease. The present study showed that personality factors are predictors of coronary heart disease
Studying the Impact of Marketing Mix on the Customers’ Satisfaction of Tabriz Iran Khodro Company
Get PDFthe aim of present research study, is to investigate impact of marketing mix on the customers’ satisfaction. Present research is among applied researches and its method is descriptive and among descriptive researches, it is of correlation type. Using Alpha Cronbach test, reliability of the questioner was obtained 93% for Tabriz Iran Khodro Company. According to the Kolmogrov -Smirnoff test results, all variables enjoy normal place . According to Pearson Correlation test results, there is a positive and significant relationship among customer’s satisfaction and place, promotion, product and price elements. According to multiple regression test results, direct effect of place factor is 82%, promotion element 77%, product element 68% and direct effect of price element is 55% in prediction of the customer’s satisfaction. From among indexes of place element, spatial place of the representatives, from among indexes of promotion element, having towing and roadside assistance, from among indexes of the product element, warranty period and from among indexes of price element special sales for different occasions played the key role in the customers’ satisfaction
Investigating the Relationship between Marketing Foundations Related to Customer Satisfaction of the Refah Bank of West Azerbaijan Province
Get PDFThe purpose of this study is to investigate the relationship between marketing foundations related to customer satisfaction of the Refah Bank of West Azerbaijan Province from the perspective of managers and employees. The basics of relationship marketing include (trust, commitment, communication, conflict management and competency). The statistical population of this study is 190 managers and employees of the Refah Bank of West Azerbaijan Province, which was selected from 7 cities of the province using cluster classification method. The data collection tool in this study was a questionnaire and Kolmogorov-Smirnov test, Pearson correlation test and Friedman test were used to analyze the data. The results of this study show that there is a significant relationship between the foundations of relationship marketing and customer satisfaction and in terms of significance level, respectively, priority, competency (0.000), trust (0.001), and communication. (0.001), conflict management (0.004), commitment (0.005), has been related to customer satisfaction with bank services. Also, according to Friedman test, the variable of trust with an average of 4.09 is known as the most important factor
Study of Serum Uric Acid Level in Acute Coronary Syndrome in Nepalese Subjects
No full textAt present, cardiovascular diseases are global health problems responsible for 17.3 million deaths per year and adding extra burden in developing countries like Nepal. Studies show that serum uric acid (SUA) can result in endothelial dysfunction which can lead to vascular disease like stroke. In this study, we determined serum uric acid levels in patients with acute coronary syndrome (ACS) and assess its risk factors. A cross sectional study was conducted in 82 patients with ACS who fulfilled the inclusion criteria included in the study and their serum uric acid level were investigated. It was found that 51 (62.2%) were males and 31 (37.8%) were females. Mean age in study population was 60.26 ± 11.34 years. Majority of the population belongs to 56-65 years age group. The mean uric acid level of our study population was 6.03 ± 1.50 mg/dl (male = 5.92 ± 1.72, female = 6.64 ± 1.53). SUA ? 7 mg/dl was maximum in 56-65 years age group and there was no association between age and SUA (P value = 0.146). Over half of the study population were hypertensive i.e. 42 (51.21%) and smoker i.e. 43 (52.43%). It showed association between SUA and ACS (P value = 0.003). Among those having diabetes, maximum have SUA ? 7 mg/dl i.e. 17 (47.22%). Among those having high cholesterol level, male have higher incidence than female with no association between T. Cholesterol and gender (P value = 0.49). The mean value of T. Cholesterol was 189.83 ± 46.81 mg/dl (male = 198.78 ± 55.19 mg/dl, female = 202.30 ± 54.92 mg/dl) with (P value = 0.52). In conclusion, the mean age of ACS patients was 60.26 years, with the peak incidence at the age of 56-65 years. The ACS had male predominance. The potential risk factors of ACS were: Age >56 years (65.83%), male sex (62.2%), dyslipidemia (35.36%, hypertension (51.2%), diabetes mellitus (43.9%), smoking (52.4%) and alcohol consumption (39%). Among these SUA significantly associated with risk factors were- Sex, Diabetes Mellitus, T. Cholesterol. There was association between serum uric acid level and ACS patients. Hypertension and smoking constitutes one of the major risk factor for ACS in study population
Role of CTSC in Glioblastoma Based on Oncomine and TCGA Database
Get PDFBackground and objective Glioblastoma (GBM) is one of the malignant tumors causing death worldwide. Most patients were found in the middle and late stages and had poor prognosis. The purpose of this study was to investigate the expression and significance of CTSC in GBM.
Methods The information about CTSC in Oncomine database was collected and analyzed twice. The role of CTSC in GBM was meta-analyzed. The expression of CTSC in glioma cell lines was retrieved by CCLE database, and the survival of patients was analyzed by TCGA database.
Results A total of 1,459 different types of CTSC were collected in Oncomine database, 134 of which had statistical differences in CTSC expression, 89 of which had increased CTSC expression and 45 of which had decreased CTSC expression. A total of 50 studies involving the expression of CTSC in GBM cancer and normal tissues included 1,189 samples.
Compared with the control group, CTSC was highly expressed in GBM (P < 0.05). Moreover, CTSC was highly expressed in glioma cell lines. There was a correlation between the expression of CTSC and the overall survival rate of GBM. The overall survival rate of patients with high expression of CTSC was worse, while the prognosis of patients with low expression of SPC24 was better (P < 0.05).
Conclusion Through the in-depth mining of oncomine gene chip database, we propose that CTSC is highly expressed in GBM tissues and is related to the prognosis of GBM, which may provide an important theoretical basis for the treatment of glioma
Results of one-stage urethroplasty for hypospadias in pediatrics – single surgeon’s experience
Get PDFIntroduction: Hypospadias repair is a challenging technique in pediatric urology with a long learning curve. This study presents the results of urethroplasty performed by a single surgeon to repair hypospadias in children and compares the surgical outcomes at different periods.
Materials and Methods: From January 2009 to February 2016, patients who were less than 18 years old and were operated for hypospadias were retrospectively reviewed and divided into two groups: group I (from January 2009 to February 2012) and group II (from March 2012 to February 2016). All operations were performed by the same pediatric surgeon, andsurgical outcomes of the two periods were compared.
Results: This study considered150 patients (69 in group I/81 in group II). The Mean operative age was 30.4±32.7 months in group I and 33.6±43.3 months in group II(p=0.309). The selected procedures mainly depended on the subjective anatomical analysis in the operating room and the surgeon’s preference. The mean follow-up duration was 21.7±28.31 months in group I and 13.6±16.6 months in group II (p=0.033).The overall complication rate was 44.9% in group Iand 35.8% in group II (p=0.316). The incidence of glanular disruption significantly decreased from 21.7% to 6.2% (p=0.007) because of the wide dissection of the glanular wings and the deep incision of the urethral plate, which led to tension-free sutures for glanular reconstruction.
Conclusions: One-stage repair of hypospadias may achieve satisfactory outcomes in cosmetic appearance and voiding function. Surgical outcomes could be improved by increasing practice
Effectiveness of Peritoneal Dialysis in Management of Acute Hyperthermia after On-Pump Heart Surgery in Infants
Get PDFIntroduction: Acute hyperthermia is a common complication in the first 24 hours after open heart surgery with the incidence of 12% to 73%. The aim of this study was to evaluate the efficiency of postoperative peritoneal dialysis for controlling acute hyperthermia in pediatrics undergoing on-pump heart surgery. Methods: We reviewed clinical outcomes of 40 infants who underwent congenital surgery from August 2016 to August 2017. Patients were divided into two groups in terms of peritoneal dialysis requirement as group A and B. Demographic data, intraoperative and postoperative variables were compared between the patients. Results: Among the 40 high risk infants who underwent cardiac surgery, 20 patients were treated with peritoneal dialysis (group A). Mean rectal temperature and incidence of acute hyperthermia in 24h after surgery were higher in group A compared to group B (p ? 0.05). Infants in group A were younger, lighter and showed lower BSA compare to group B (p < 0.05). Also, higher concentration of serum potassium and lower urinary output were seen in group A compared to group B (p = 0.05). The incidence of neurological events was significantly higher in patients of group A (p < 0.05). Intubation time and intensive care unit stay was significantly more prolonged in the group A with peritoneal dialysis (p ? 0.05). Conclusion: Peritoneal dialysis performance was effective in treatment of induced hyperthermia in the first 24 h after operation. Indeed, younger age and lighter weight children are more prone to postoperative complication related to cardiopulmonary bypass surgery
Aqueous Extract of Sorindeia Juglandifolia Leaves Protects Methotrexate-Induced Liver and Kidney Damage in Rat
Get PDFIntroduction: Liver and kidney affection is a life-threatening disease caused by factors including drug-based treatment. Treatment based on methotrexate could result in liver and kidney damages. The study evaluates the preventive effects of Sorindeia juglandifolia leaves on methotrexate-induced liver and kidney impairment in rat.
Methods: Healthy rats divided into 6 groups daily received distilled water, methotrexate (20 mg/kg), sub-cutaneous injection of L-carnitin (500 mg/kg) and methotrexate and the plant extract doses of 150, 250 and 350 mg/kg and methotrexate for 10 days. During treatment, body weight was recorded. At the end of the treatment, animals were sacrificed; venous blood were collected for haematological and biochemical analysis. Liver and kidney were collected for oxidative markers and histological examination.
Results: The consecutive treatment of animals with plant extract and methotrexate showed a significant prevention of the body weight decrease and enhancement of the relative weight of liver and kidney. Sorindeia. juglandifolia extract also protected from the significant increase in transaminase activities, bilirubin and protein level, hypercholesterolemia, atherogenic index, and in the kidney from hypercreatininemia and the increase in serum urea level. The extract prevented the decrease of sodium level and glomerular filtration. Plant extract improved reactive oxygen species detoxification agents and protected from the histological disorganization of the liver and kidney tissues, observed in the MTX control.
Conclusion: Sorindeia juglandifolia leaves extract expressed hepatorenal protective properties and could be useful to prevent liver and kidney damage induce by methotrexate
On the Possible Anomaly of Asymmetric Weight Reduction of Gyroscopes under Rotation
Get PDFIn this work, we discuss a theoretical model that can describe novel phenomena of induction of weak anomalous forces in gyroscopes under right rotations either in rest frame of the laboratory or in free-fall. The effect detected in the gyroscopes cannot be successfully associated to any conventional theory. So, we elaborated the theoretical description of such forces in both experiments by means of a model based on the generalized quantum entanglement framework, by considering as quantum witnesses the magnetic permeability and as macroscopic observable the angular momentum of the gyroscopes rotors. Our calculations indicate that there is a good agreement with the experimental data obtained from literature for most rotation frequencies measured