25949 research outputs found
Sort by
Estudi de l’impacte del turisme sobre els residents a Palamós
No full textAquest Treball de final de grau analitza l’impacte del turisme sobre els residents a
Palamós des d’un punt de vista econòmic, de benestar i qualitat de vida, sociocultural,
mediambiental i en termes generals. Per fer-ho, s’ha realitzat una enquesta on s’han
recollit les percepcions de 442 residents a partir de la informació quantitativa obtinguda
en una escala de satisfacció de Likert. Els resultats permeten concloure que els
palamosins constitueixen una població conscient i crítica amb el model turístic, motor
econòmic principal del poble. Aquesta informació té implicacions per la gestió del turisme
a PalamósThis final thesis analyses the impact of tourism on the residents of Palamós from an
economic, welfare and quality of life, sociocultural and environmental point of view and
in general terms. To do so, a survey was carried out in which the perceptions of 442
residents were gathered from the quantitative information obtained from a Likert
satisfaction scale. The results allow us to conclude that the people of Palamós are aware
of and critical of the tourist model, the town’s main economic engine. This information
has implications for the management of tourism in Palamós81112141
So, what do we talk about when we talk about transmedia storytelling in education? A systematic literature review
No full textTransmedia storytelling is an increasingly used didactic approach to develop digital and transmedia competences in education. However, how the concept of transmedia storytelling is used beyond its foundational definition—which underpins educational practices—remains underexplored. The long period since Jenkins's initial definition, its adaptation to education, and the lack of reviews on its educational use justify the need for this study. The systematic literature review was conducted using the keywords “transmedia” AND “education”, searching in four databases which identified a total of 573 studies, with a final inclusion of 43, with a focus ranging from primary to secondary education, although post-compulsory cases are identified. Findings reveal Jenkins's foundational definition strongly influences how transmedia storytelling is conceptualised in the educational field. However, discrepancies emerge when comparing definitions to their actual practices, revealing a heterogeneous, often implicit use of ‘transmedia’ and ‘storytelling’. This prompts an examination of the concept's practical utilisation, as opposed to its theoretical characterisation. Therefore, a plural scenario of uses pivoting under the very same Jenkins definition is characterised, which can be grouped under five different uses of the term ‘transmedia storytelling’: (1) transmedia and transmedia storytelling as a synonym; (2) crossmedia, transmedia narratives, and transmedia as synonyms; (3) use of the narrative (4) media focus; and (5) transmedia mimicking daily life. Consequently, this facilitates a thorough investigation into a wide array of transmedia practices within the educational sector, which have previously been concealed under the definition of transmedia storytelling. The discussion underscores that transmedia storytelling represents merely one approach within the broader framework of transmedia. It emphasises the necessity of recognising that transmedia encompasses and can extend beyond the confines of transmedia storytellingOpen Access funding provided thanks to the CRUE-CSIC agreement with Wiley
First Row Transition Metals in Olefin Metathesis: The Role of Iron and Manganese
No full textThis article has been corrected. Correction to "First Row Transition Metals in Olefin Metathesis: The Role of Iron and Manganese”, ChemCatChem, 2025-08-05, vol. 17, iss. 16Olefin metathesis has traditionally been dominated by molybdenum and ruthenium-based catalysts, but the pursuit of sustainable and earth-abundant alternatives has driven interest in first-row transition metals particularly iron. While iron is an attractive candidate due to its abundance, low toxicity, and cost-effectiveness, significant challenges hinder its successful implementation in metathesis reactions. This review examines the electronic and structural properties of iron that contribute to its catalytic limitations, including high-spin configurations, weak metal-alkylidene interactions, and a pronounced tendency toward cyclopropanation. Computational and experimental efforts to overcome these obstacles are discussed, focusing on ligand design strategies and mechanistic insights. Additionally, the potential of manganese as an alternative to iron is explored. This work underscores the complexities of first-row transition metal catalysts in olefin metathesis and highlights future directions for achieving practical, efficient iron-based systems. Future research should focus on refining ligand architectures to stabilize key intermediates, leveraging computational insights to predict reactivity trends, and further investigating the role of metal oxidation states in metathesis activity. While the transition to first-row transition metals remains a challenge, ongoing advancements continue to push the boundaries of sustainable catalysis, bringing the dream of practical iron- or manganese-based olefin metathesis closer to realityResearch funding: Polish National Science Center. Grant Number: UMO-2023/51/D/ST4/01561; Ministère de la Recherche et des Nouvelles Technologies Normandie Université University of Caen Normandie CNRS Région Normandie. Grant Number: ANR-11-LABEX-0029 and European Union. Grant Number: HORIZON-MSCA-2022-DN-01 Project:101119574.
Open Access funding provided thanks to the CRUE-CSIC agreement with Wile
Assessing skeletal maturity in a UK modern female population
No full textObjective: The study aimed to examine the accuracy of Greulich and Pyle (GP) methodology for estimating age in a female UK sample since there is a dearth of studies testing its applicability in the UK. Materials and methods: Radiographs from the left wrist and hand belonging to 257 female individuals from two different hospitals from the UK ranging from 10 to 17 years old were analysed. Correlation was performed between skeletal age (SA) and chronological age (CA) values as well as mean comparisons. In addition, the mean difference (MD) and mean absolute difference (MAD) between these two parameters were also examined to study inaccuracy values. Results: A strong correlation was found between SA and CA (r = 0.887; p < 0.001). The MD between SA and CA is positive (0.51 ± 12.43 months), meaning that SA based on Greulich and Pyle atlas overestimates CA in general terms (minimum: − 40.17 months; maximum: 31.13 months). In the case of MAD, the mean value is 9.96 ± 7.44 months (minimum: 0.07 months; maximum: 40.17 months). In addition, no significant differences were found between SA and CA either in the global sample or in most of the age cohorts, with two exceptions: 14-year-olds, where mean SA was significantly higher than CA, and 16-year-olds, where the opposite results were observed. Conclusion: These results suggest that the GP atlas can be applied to the present female UK population, although caution must be taken when applied to estimating the age of post-pubertal UK girlsOpen Access funding provided thanks to the CRUE-CSIC agreement with Springer Natur
Generative artificial intelligence in advertising. Field applications in Rio de Janeiro and Catalonia
No full textThe emergence of Artificial Intelligence has revolutionized industries in various productive sectors on an international level. Advertising agencies are not immune to this reality and have also experienced the effects of AI through the advent and widespread use of technologies that enable the design, creation, editing, and writing of content for the advertising industry. This article allows us to measure the impact of the arrival of AI in several advertising agencies, independent and holding companies (such as McCann and Havas Media) in Rio de Janeiro and Catalonia. The research analyses the use and integration of these programs in creative and productive processes based on 25 in-depth interviews with 13 directors and 12 creatives in both regions. The results show that agencies are using generative AI tools, but for different purposes, and that in some cases, AI is related to the advertising creation process, while in others, it is used for tasks related to the design of strategic communication plans or even the design of prototypes and models. Although there is unanimous agreement on the benefits of AI, there are concerns about ethical issues and its use in the finalists' work. This article allows us to glimpse new lines of research related to the implementation of generative AI tools in advertising creativity, customer relationship management, and advertising productionThis research was carried out by PUBCOMTEC, a research group formed by the University of Girona (Faculty of Tourism) and Universidade Federal do Rio de Janeiro (Escola de Comunicação).
Open Access funding provided thanks to the CSUC agreement with Elsevier
Effects of wildfire and post‐fire salvage logging on insects with below‐ and aboveground life phases: cicadas as an ecological model
No full textENG- Wildfires are becoming increasingly frequent and intense in the Mediterranean region, and the way we manage forests after fire—especially through logging to recover burnt wood—can have a significant impact on biodiversity. This thesis explores how these disturbances affect cicadas, insects that spend years underground as nymphs and emerge for only a few days as flying adults.
To study this, three aspects were addressed. First, using stable isotope analysis of the exuviae (the external skeleton shed during their final molt) of Cicada orni, it was found that cicadas may adjust their underground diet depending on the plant species that regrow after the fire, taking advantage, for example, of the roots of shrubs such as Genista scorpius. This finding may indicate a strong capacity for adaptation to environmental changes in these insects.
Second, through radiotelemetry, the movements of adult cicadas (Lyristes plebejus) were tracked in both burned and unburned areas. The results show that cicada movements, home ranges, and survival are influenced by the effects of wildfires and post-fire logging. Specifically, in burned areas, cicadas exhibit larger movements and lower survival rates, particularly in those areas that have been both burned and logged.
Finally, wax models of cicadas in different colors—black and gray—were placed on burned and unburned trees to assess predation risk. The black models—resembling species of the genus Tibicina—experienced lower predation when placed on charred trunks, suggesting that having darker pigmentation may be an evolutionary adaptation of certain cicada species to remain camouflaged after fire.
Overall, this study highlights the need to adopt integrative post-fire management strategies. These should consider not only forest exploitation but also the preservation of key landscape features such as unburned patches, which serve as refuges that support wildlife survival and ecosystem recovery. Therefore, it is crucial to rethink the management of burned forests with a long-term ecological perspective that minimizes additional impacts and promotes the natural resilience of the ecosystemCAT- Els incendis forestals són cada cop més freqüents i intensos a la regió mediterrània, i la manera com gestionem els boscos després del foc —especialment amb la tala per recuperar fusta cremada— pot tenir un impacte important en la biodiversitat. En aquesta tesi, s’ha estudiat com aquestes pertorbacions afecten les cigales, uns insectes que passen anys sota terra com a nimfes i emergeixen durant uns pocs dies com a adults voladors.
Per analitzar-ho, s’han estudiat tres aspectes. Primer, amb anàlisis d’isòtops estables de les exúvies (l’esquelet extern que alliberen en la seva darrera muda) de la cigala del pi (Cicada orni), s’ha vist que les cigales podrien ajustar la seva dieta subterrània en funció de les plantes que rebroten després del foc, aprofitant, per exemple, les arrels d’espècies com l’argelaga borda. Aquest fet podria revelar una forta adaptació als canvis ambientals per part d’aquests insectes.
En segon lloc, mitjançant radiotelemetria, s’han seguit els desplaçaments de cigales (Lyristes plebejus) adultes en zones cremades i no cremades. Els resultats mostren que els moviments, els dominis vitals i la supervivència de les cigales estan influenciats per l’efecte dels incendis i la tala postincendi. En concret, en les zones cremades, les cigales presenten moviments més grans i una longevitat més baixa, especialment en aquelles àrees que han estat tant cremades com talades.
Finalment, es van col·locar models de cigales de cera de colors diferents, negres i grises, en arbres cremats i no cremats per avaluar-ne el risc de depredació. Els models negres —similars a les espècies del gènere Tibicina— patien menys depredació quan estaven situades sobre troncs cremats, suggerint que tenir pigmentació fosca podria ser una adaptació evolutiva d’algunes espècies de cigales per passar desapercebudes després del pas del foc.
En conjunt, aquest estudi subratlla la necessitat d’adoptar estratègies de gestió postincendi integradores. Aquestes haurien de tenir en compte no només l’explotació forestal, sinó també la preservació d’elements clau del paisatge com les illes no cremades, refugis que afavoreixen la supervivència de la fauna i la recuperació de l’ecosistema. Així doncs, cal repensar la gestió forestal dels boscos cremats amb una visió ecològica a llarg termini, que minimitzi els impactes addicionals i promogui la resiliència natural de l’ecosistemaPrograma de Doctorat en Medi Ambien
Unió seqüencial de múltiples dominis proteics in vivo i in vitro utilitzant trans-inteïnes ortogonals
No full textENG- Inteins are a type of protein that can excise themselves from inside a precursor protein sequence, joining the two ends (named exteins) forming a mature protein. This process is termed protein splicing. One particular kind of inteins are trans-inteins, which are expressed in two different genes forming two protein precursors, each with one intein subunit fused to the corresponding extein. Although they are expressed separately, they can join afterwards and carry out the protein splicing reaction the same way, linking together the two exteins to form a single final protein.
Inteins are versatile biotechnological tools, and multiple applications have been developed to take advantage of their unique properties. One of such applications consists in taking advantage of the ability of trans-inteins of joining two exteins that are expressed independently to label each of these exteins differently and obtain a single mature protein with a fragment differentially labelled. This is useful to be able to express a fragment in the presence of 13C i 15N isotopes, which can allow for the study of the structure and molecular dynamics of that fragment via nuclear magnetic resonance. This is interesting in order to study the structure of specific domains in proteins of big size, such as TDP-43, a protein that’s related to pathologies like amiotrophic lateral sclerosis.
In this thesis we have studied four trans-inteins: gp41-1, gp41-8, IMPDH-1 and NrdJ-1. Initially, we evaluated their splicing activity and orthogonality: that is, studying if their subunits are specific to themselves and they don’t cross-react with one another. In fact, we have demonstrated that they indeed behave orthogonally and, additionally, confirmed they can carry out protein splicing quickly and efficiently.
Secondly, we designed a system using these inteins in which we can fuse up to four different protein fragments expressed independently. At the same time, we have studied the ability for these inteins to still carry out protein splicing even when modifying the protein sequences adjacent to them. We have been successful in demonstrating that, even thought the efficiency of the splicing reaction was affected when modifying these sequences, it is possible to obtain a complete protein from four independently expressed protein fragments using three orthogonal inteins with a good yield.
Finally, we used this intein system to obtain a full-length TDP-43 protein from four of its independent domains. In this case, only three of the domains were successfully fused, so further efforts should be conducted to optimize the system described in this thesis.
Altogether, this work poses a progress in the use and understanding of inteins as biotechnological tools, in addition to offering new and relevant information in the limitations of the four inteins of this studyCAT- Les inteïnes són un tipus de proteïnes que poden escindir-se de l’interior d’una proteïna precursora, unint els dos extrems (anomenats exteïnes) per formar una proteïna madura. Aquest procés s’anomena splicing, o tall i unió de proteïnes. Dins de les inteïnes hi podem destacar les inteïnes partides, les quals s’expressen en dos gens diferents formant dos precursors proteics, cadascun amb una subunitat de la inteïna i la seva exteïna corresponent. Tot i expressar-se com a dues proteïnes independents, aquest tipus d’inteïnes poden unir-se després d’haver-se expressat i dur a terme la reacció d’splicing de la mateixa forma, unint així les dues exteïnes per formar una única proteïna final.
Les inteïnes són eines biotecnològiques molt versàtils i s’han desenvolupat múltiples aplicacions per aprofitar les seves propietats úniques. Una d’aquestes aplicacions consisteix en aprofitar la capacitat de les inteïnes partides d’unir exteïnes expressades independentment per poder produir cada exteïna en condicions diferents, i d’aquesta manera obtenir una proteïna madura amb fragments marcats de forma diferencial. Una utilitat d’aquest mètodes és marcar un fragment expressant-lo en presència d’isòtops de 13C i 15N per estudiar l’estructura i la dinàmica molecular del fragment marcat per ressonància magnètica nuclear. Això és interessant per estudiar l’estructura de dominis concrets de proteïnes de gran mida, com el cas de la proteïna TDP-43, relacionada amb patologies com l’esclerosi lateral amiotròfica.
En aquesta tesi hem estudiat quatre inteïnes partides: gp41-1, gp41-8, IMPDH-1 i NrdJ-1. Inicialment, hem avaluat la seva activitat d’splicing i la seva ortogonalitat: això és, estudiar si les subunitats aquestes inteïnes partides són específiques per a elles mateixes i no reaccionen de forma creuada. Hem demostrat que aquestes inteïnes es comporten de forma ortogonal i a més a més s’ha confirmat que poden dur a terme la unió d’exteïnes de forma ràpida i eficient.
En segon lloc, hem dissenyat un sistema d’unió de quatre fragments de proteïna utilitzant aquestes inteïnes. Alhora, s’ha estudiat la capacitat d’aquestes inteïnes de dur a terme la reacció d’splicing i unir aquests fragments modificant la seqüència proteica que es troba adjacent a la seqüència de la inteïna. Hem aconseguit demostrar que, malgrat una disminució en l’eficiència de la reacció en modificar les seqüències adjacents, es pot obtenir una proteïna completa a partir de quatre fragments expressats independentment mitjançant tres inteïnes ortogonals amb un bon rendiment.
Finalment, hem utilitzat el sistema establert per a obtenir la proteïna TDP-43 completa a partir de quatre dels seus dominis independents. En aquest cas, només s’han aconseguit fusionar tres dels dominis i, per tant, cal treballar en una optimització del sistema descrit en aquesta tesi.
En conclusió, aquest treball suposa un progrés en la utilització d’inteïnes com a eines biotecnològiques, a més a més de proporcionar informació molt rellevant sobre les limitacions de les quatre inteïnes estudiadesAquesta recerca ha estat finançada pel Ministeri d'Economia i Competitivitat, a través del projecte BIO2013-43517, de la Universitat de Girona a través del projecte MPCUdG2016-18, i per la DGU, Generalitat de Catalunya a través del projecte 2017-SGR 172
The Predictive Value of Emotion Regulation in Cocaine Use Disorder Severity: Psychotherapeutic Implications During Hospitalization for Detoxification
No full textObjective: Traditional treatment approaches in cocaine use disorder (CUD) still report high rates of poor outcomes. Emotion regulation (ER) is a transdiagnostic factor that may contribute to the initiation and maintenance of CUD, strengthening addiction severity. A deeper understanding of ER in this population is crucial for improving treatment outcomes. This study explores whether ER difficulties at treatment entry predict addiction severity and withdrawal symptom severity after discharge in patients with CUD. Secondarily, it examines whether withdrawal symptom severity mediates the relationship between ER difficulties and relapse. Methods: A total of 70 CUD patients underwent a 14-day inpatient detoxification. At admission, cocaine use-related variables and ER questionnaires (DERS and ERQ) were registered. After discharge, addiction severity (SDS), craving (WCS), cocaine withdrawal symptom severity (CSSA) and relapse were recorded. Multiple linear regression and mediation analysis were conducted to address the primary and secondary aims, respectively. This study draws on data from a larger randomized clinical trial. Results: Impulse control difficulties and nonacceptance of emotional responses predicted SDS, and nonacceptance of emotional responses predicted CSSA. However, mediation analyses showed no indirect effect of DERS total score on relapse through the effect of the mediating variable CSSA. Conclusion: ER screening at hospitalization admission may optimize treatment by identifying high-risk CUD patients. Third-generation therapies targeting ER skills may enhance outcomes by helping patients manage emotional distress, potentially reducing addiction severity and withdrawal symptoms. Because of mixed results and the exploratory nature of this study, further research on the ER role in this context is neededResearch funding: Instituto de Salud Carlos III. Grant Number: PI20/00929; European Regional Development Fund; Instituto Carlos III and Fundació Privada Hospital de la Santa Creu i Sant Pau.
Open Access fundingprovided thanks to the CRUE- CSIC agreement with WileyOpen Access funding provided thanks to the CRUE-CSIC agreement with Wile
Allport en la millora de cohesió de grup: anàlisi de la influència de l’aplicació de la teoria de contacte intergrupal d’Allport a la cohesió de grup classe. Estudi d’un cas
No full textLa recerca explora la influència de la teoria de contacte intergrupal d’Allport en racons de jocs cooperatius en la cohesió de grup. A partir d’un mètode quasiexperimental, s’administren tres instruments distribuïts principalment en pretest/posttest per determinar com una situació de contacte en un context específic permet establir nous vincles afectius positius. Els resultats indiquen que l’estudi permet determinar el tipus de relació a establir amb els companys, però no és sinònim que sigui positiva i millori la cohesió. Tot i això, la recerca ha aconseguit que els alumnes estiguin més connectats, evitant l’aïllament i fomentant la inclusió al grup.The research explores the influence of Allport's intergroup contact theory in cooperative play corners on group cohesion. Based on a quasi-experimental method, three instruments are administered, mainly distributed in pretest/posttest, to determine how a contact situation in a specific context allows the establishment of new positive affective bonds. The results indicate that the study allows the determination of the type of relationship to be established with classmates, but it is not synonymous with it being positive and improving cohesion. However, the research has achieved that students are more connected, avoiding isolation and promoting inclusion in the group
Iniciació a la consciència fonològica amb infants de 3 anys a través d’un conte musicat i personalitzat amb els noms propis
No full textEl present estudi analitza la influència de l’ús del conte musicat personalitzat amb les inicials dels alumnes com a eina pedagògica per estimular la iniciació a la consciència fonològica amb infants de 3 anys. A través d’una metodologia d’investigació-acció, s’ha dissenyat i implementat una situació d’aprenentatge “Descobrim els sons de les lletres amb la Llumeta i els seus amics”, en un grup de 18 alumnes d’Educació Infantil 3. Els resultats mostren que aquest recurs ha estat eficaç per afavorir l’aprenentatge significatiu de la consciència fonològica i captar l’atenció i motivació dels alumnes des del primer moment.The present study analyzes the influence of the use of the customized musiced story with the initials of the students as a pedagogical tool to stimulate the initiation to phonological awareness with children of 3 years. Through an action-research methodology, a learning situation has been designed and implemented “We discover the sounds of letters with the Llumeta and her friends”, in a group of 18 Early Childhood Education students 3. The results show that this resource has been effective in favoring significant learning of phonological awareness and capturing the attention and motivation of students from the first moment