Karamanoğlu Mehmetbey University
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Test of lepton flavor universality in semileptonic (formula presented) meson decays in proton-proton collisions at (formula presented)
No full textA measurement of the ratio of branching fractions (Formula presented) in the (Formula presented), (Formula presented) decay channel is presented. This measurement uses a sample of proton-proton collision data collected at a center-of-mass energy of (Formula presented) by the CMS experiment in 2018, corresponding to an integrated luminosity of (Formula presented). The measured ratio, (Formula presented), agrees with the value of (Formula presented) predicted by the standard model, which assumes lepton flavor universality. By testing lepton flavor universality, this measurement is a probe of new physics using (Formula presented) mesons, which are currently only produced at the LHC. © 2025 CERN, for the CMS Collaboratio
Ağrı iletiminde dominant hemisfer etkili mi?
Get PDFObjective: Propofol is one of the frequently used anesthetic agents. The most common side effect of it is injection pain. Hand dominance is one of the clinical factors that should be evaluated in pain sensitivity. The effect of hand dominance on many pain factors has been examined, but no clear conclusion has been reached. For this purpose, we aimed to evaluate the effect of this condition on propofol injection pain in patients with right- or lefthand dominance. Method: Our study included 163 patients aged 18-70 who would undergo general anesthesia with propofol for any surgical procedure in the operating room. Patients were randomly divided into 4 groups; group 1 (n=39) right-handed patients with vascular access on the back of the right hand, group 2 (n=45) right-handed patients with vascular access on the back of the left hand, group 3 (n=40) left-handed patients with vascular access on the back of the left hand, group 4 (n=39) were left-handed and had vascular access from the back of their right hand. It was evaluated with a 4-point verbal pain scale following propofol induction. Results: When dominant and non-dominant hand cannulation were compared in terms of pain score, no difference was found. No significant difference was found when the incidence of pain was evaluated according to the direction of the dominant hand and the cannulation side. Conclusion: In our study, no significant difference was found in propofol injection pain in terms of hand dominance and cannulation side
Decoding degradation: The synergy of partial differential equations and advanced predictive models for lithium-ion battery
No full textRecent advancements in machine learning (ML) algorithms have transformed Li-Ion battery analysis, focusing on crucial parameters like State of Charge (SOC), State of Health (SOH), and Remaining Useful Life (RUL). However, due to increasing computational complexity and lack of fundamental process understanding within the developed models, conventional predictive tools suffer its integration in real world applications. To address this gap, our study introduces a hybrid modeling approach consisting of two stages. In the first stage, we apply various machine learning algorithms to predict battery degradation using empirical data, focusing on capturing the initial patterns of battery behavior under different operating conditions. In the second stage, we enhance these predictions by integrating Partial Differential Equations (PDEs) that incorporate fundamental physical principles governing battery performance. This combination creates a physics-informed ML model that bridges the gap between empirical data and theoretical understanding. The integration of PDEs significantly improves the model's accuracy in predicting both degradation and discharge capacity. Our results demonstrate a marked enhancement in key performance metrics, with the hybrid model achieving a Mean Square Error (MSE) of 0.2091, Root Mean Square Error (RMSE) of 0.4572 and Mean Absolute Error (MAE) of 0.2555. In comparison, the errors from the initial stage-one ML predictions were substantially higher, with MSE, RMSE, and MAE values of 10.3648, 3.2194, and 0.7392, respectively. These findings highlight the hybrid model's effectiveness and its potential to significantly improve battery management practices, ultimately contributing to the extension of battery lifespan. © 2024 Elsevier B.V.Pandit Deendayal Energy University; DST SERB, (IPA/2021/96
Designing human–robot ınteraction algorithms for developing metacognitive skills
No full textIn today's technology, robots are involved in all life aspects. Therefore, it is inconceivable that robots will not affect the field of education either. Robot simulators can help developers test and improve intelligent systems before putting them in natural environments. In this study, the use of robots in education has been discussed in relation to the development of metacognitive abilities. A simulation environment was prepared for testing and developing the methods that follow learning models in human–robot interaction. The simulation is about a humanoid robot making an engineering lesson plan. It has been tested on a group of academicians consisting of 64 (32 persons in the experimental group and 32 persons in the control group) persons working in Computer Engineering in the 2021–2022 academic year. The application process includes an 8-week course period. The data as the result of the test were collected from both groups using the MCQ-30 scale and from the experimental group by the metacognitive strategy questions after preparing the engineering lesson plans made by robot simulation. Evaluation of the data showed that the robot simulation was effective in the metacognition scores of the people in the experimental group, and the success level of the people in the control group did not change significantly, considering the results of the pretest and the posttest. © 2024 Wiley Periodicals LLC
The Effects of COVID-19 on Tinnitus Severity and Quality of Life in Individuals With Subjective Tinnitus
Get PDFPurpose: This study aimed to investigate the effects of the SARS-CoV-2 virus (COVID-19) on tinnitus severity and quality of life in infected and non-infected individuals who were re-admitted to our clinic after the COVID-19 outbreak.
Methods: The study involved both retrospective and prospective data analysis. The study included 30 individuals aged 20-65 years with normal hearing who had undergone psychoacoustic, tinnitus, and psychosomatic evaluations before the pandemic. Participants were divided into Group 1 (n = 15, COVID-19 negative) and Group 2 (n = 15, COVID-19 positive). Before the pandemic, tinnitus-related evaluations of all participants (i.e., pure tone audiometry [PTA], tinnitus frequency, loudness, minimum masking level [MML], and residual inhibition [RI]) were conducted, and the Tinnitus Handicap Inventory (THI), Visual Analog Scale (VAS), and Short Form 36 (SF-36) were administered to all participants. All assessments were repeated after the outbreak of the pandemic.
Results: There was no significant difference in the mean PTA thresholds of both groups before and after the pandemic (p > 0.05). There was a significant increase in tinnitus severity after COVID-19 infection in Group 2 (p 0.05).
Conclusion: Although negative effects of the pandemic were observed in individuals with tinnitus who were not infected with COVID-19, both the quality of life and tinnitus severity of individuals with tinnitus who were infected with COVID-19 worsened
Hazelnut by-products as a valuable resource: Lipid peroxidation inhibition effect, bioaccessibility and antidiabetic properties
No full textThe aim of this study is to determine the chemical and molecular properties of hazelnut by-products, to measure the bioaccessibility values of phenolic compounds found in the structure of these wastes and to reveal their antidiabetic and lipid peroxidation (LPO) inhibition effects. The highest moisture and protein content were found in skin samples with 6.33% and 7.70%, respectively. The predominant fatty acid in hazelnut skin is oleic acid, which constitutes 78.65% of the total fatty acid composition. The highest antioxidant activity value was measured in the shell with an IC50 value of 19.08 mg/mL. The sample with the highest content of gallic acid and protocatechuic acid content was the skin extract. The dominant phenolic component in the shell and husk samples was kaempferol, while in the skin sample it was rutin. Shell bioaccessibility was found to be much higher for o-coumaric acid (45.83%), rutin (49.25%) and kaempferol (46.32%) components. The bioaccessibility of the shell sample in total phenolic concentration was measured as 45.87%. The highest LPO inhibition value belonged to the shell sample with an IC50 of 4.50 mg/mL, while the lowest value belonged to the husk sample with an IC50 value of 25.03 mg/mL. The highest antidiabetic effect was observed in the shell sample with values of 3.55 mg/mL and 25.44 mg/mL for α-amylase and α-glucosidase inhibition, respectively. The highest recovery belonged to 4-Hydroxybenzoic acid in the skin sample. As a result, it was concluded that hazelnut by-products, especially the shell, exhibit high antioxidant effects, have antidiabetic and LPO inhibition properties thanks to their bioactive components and high bioaccessibility values. Thus, they have valuable usage opportunities in the fields of food, pharmacology and medicine. © 2025 Elsevier Lt
Search for central exclusive production of top quark pairs in proton-proton collisions at √s=13 tev with tagged protons
No full textA search for the central exclusive production of top quark-antiquark pairs (t (t) over bar) is performed for the first time using proton-tagged events in proton-proton collisions at the LHC at a centre-of-mass energy of 13TeV. The data correspond to an integrated luminosity of 29.4 fb(-1). The t (t) over bar decay products are reconstructed using the central CMS detector, while forward protons are measured in the CMS-TOTEM precision proton spectrometer. An observed (expected) upper bound on the production cross section of 0.59 (1.14) pb is set at 95% confidence level, for collisions of protons with fractional momentum losses between 2 and 20%
Investigation of Transcription Factor and Cytokine Gene Expression Levels in Helper T Cell Subsets Among Turkish Patients Diagnosed with ICF2 (Novel ZBTB24 gene Variant) and ICF3 (CDCA7 Variant) Syndrome
No full textImmunodeficiency, centromeric region instability, facial anomalies syndrome (ICF), is a rare disease with autosomal recessive inheritance. ICF syndrome. It has been reported that ICF syndrome is caused by mutations in the DNMT3B (ICF1), ZBTB24 (ICF2), CDCA7 (ICF3), and HELLS (ICF4) genes. As a result of literature research, there are no studies on transcription factor and cytokine expressions of helper T cell subsets in ICF syndrome. In the study; Th1 (TBET, STAT1, STAT4), Th2 (GATA3, STAT6), Th17 (RORgt, STAT3), Treg (FoxP3, STAT5) transcription factors and the major cytokines of these cells (Th1; IFNG, Th2; IL4, Th17; IL17A-21-22, Treg; IL10, TGF?) expressions were aimed to be evaluated by qRT-PCR. Patients (ICF3: three patients; ICF2: two patients), six heterozygous individual and five healthy controls were included in the study. All patients had hypogammaglobulinemia. Except for the CD19 cells of P2 from patients diagnosed with ICF3, the CD3, CD4, CD8, and CD19 cells in the other ICF3 patients were normal. However, the rates of these cells were low in patients with ICF2 syndrome. Factors belonging to patients’ Th1, Th17 and Treg cells were significantly lower than the control. Additionally, novel mutation was detected in ZBTB24 gene (c.1121–2 A > T). Our study is the first molecular study on Th cell subsets in patients with ICF syndrome and a new mutation that causes ICF2 syndrome has been identified. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024
Exploring Nanoscale Perovskite Materials for Next-Generation Photodetectors: A Comprehensive Review and Future Directions
No full textThe rapid advancement of nanotechnology has sparked much interest in applying nanoscale perovskite materials for photodetection applications. These materials are promising candidates for next-generation photodetectors (PDs) due to their unique optoelectronic properties and flexible synthesis routes. This review explores the approaches used in the development and use of optoelectronic devices made of different nanoscale perovskite architectures, including quantum dots, nanosheets, nanorods, nanowires, and nanocrystals. Through a thorough analysis of recent literature, the review also addresses common issues like the mechanisms underlying the degradation of perovskite PDs and offers perspectives on potential solutions to improve stability and scalability that impede widespread implementation. In addition, it highlights that photodetection encompasses the detection of light fields in dimensions other than light intensity and suggests potential avenues for future research to overcome these obstacles and fully realize the potential of nanoscale perovskite materials in state-of-the-art photodetection systems. This review provides a comprehensive overview of nanoscale perovskite PDs and guides future research efforts towards improved performance and wider applicability, making it a valuable resource for researchers. (Figure presented.) © The Author(s) 2024.National Research Foundation of Korea, NRF; Anhui Natural Science Foundation; MSIT, (RS-2022–00165798); Natural Science Foundation of Anhui Province, (2308085MF211); Natural Science Foundation of Anhui Province; King Khalid University, KKU, (R.G.P.2/491/45); King Khalid University, KK
İnsight into the photoluminescence of ba2cd(bo3)2: re3+ (re = dy, tb) phosphors
No full textDy3+ and Tb3+ ions doped Ba2Cd(BO3)2 phosphors with varying concentrations (2, 3, 4, 5, 6 mol%) were produced via the solid-state synthesis method in air. The as-synthesized phosphors were characterized. The photoluminescence (PL) and photoluminescence excitation (PLE) spectra of Ba2Cd(BO3)2 phosphors doped with 2, 3, 4, 5, and 6 mol% Dy3+ ions reveal four distinct emission bands in the blue, yellow, and red regions, with the 575 nm emission band (4F9/2 -> 6H13/2, electric dipole transition) exhibiting a notably higher intensity than the 481 nm band (4F9/2 -> 6H15/2, magnetic dipole transition). The optimal Dy3+ doping concentration was identified as 5 mol%, beyond which concentration quenching effects became apparent. Additionally, excitation and emission spectra of Ba2Cd(BO3)2 phosphors doped with 2, 3, 4, 5, and 6 mol% Tb3+ ions demonstrate efficient energy absorption at approximately 225 nm, with characteristic emission bands observed at 415, 436, 488, 544, 586, and 621 nm, corresponding to the 5D3 -> 7F5, 5D3 -> 7F4, 5D4 -> 7F6, 5D4 -> 7F5, 5D4 -> 7F4, and 5D4 -> 7F3 transitions, respectively. The ideal concentrations for Dy3+ (5 mol%) and Tb3+ (6 mol%) in Ba2Cd(BO3)2 are identified at x = 0.3717, y = 0.4064, and x = 0.2902, y = 0.5344, respectively, as per the Commission Internationale de l'Eclairage (CIE) color spectrum, positioning Dy3+-doped phosphors within the yellow spectrum and Tb3+-doped phosphors within the green spectrum. These phosphors exhibit vibrant yellow and green luminescence, demonstrating their suitability as candidates for applications in these hues. They can be employed when stimulated by near-UV, UV, and blue laser diodes for WLEDs