Showa University Academic Resource Repository / 昭和大学学術業績リポジトリ
Not a member yet
3721 research outputs found
Sort by
上顎歯肉と下顎骨に生じたランゲルハンス細胞組織球症に放射線治療が奏功した1例
Get PDFランゲルハンス細胞組織球症はLangerhans細胞の浸潤，増殖を組織学的特徴とする原因不明の病変で，成人の発症は少ないといわれている．治療法として手術療法，化学療法，放射線療法，または併用療法等さまざまな治療法が検討されているが，いまだ統一した見解は得られておらず，治療法が確立されていないのが現状である．患者は36歳男性，左側上顎第一大臼歯歯肉の疼痛と腫脹を主訴に当院を受診した．初診時左側上顎歯肉の腫脹を認めた．生検にてランゲルハンス細胞組織球症の確定診断を得たため摘出施行．経過観察を行っていたところ，術後2か月のパノラマX線写真にて右側下顎骨の透過像が右側下顎大臼歯根尖部に拡大したため，再度右側下顎腫瘍摘出術を施行した．しかし，再摘出2か月後のパノラマX線写真でさらに前方に新たな病変の出現を認め，手術療法では根治困難と判断，ステロイド療法（リン酸デキサメタゾン3.3mgの局注）を週に1回，合計で25回施行したが腫瘍の制御は困難であった．そこで放射線治療を行うこととなり，右側下顎にtotal 10Gyの放射線照射を施行した．その後，腫瘍の再発は認められず経過良好である．departmental bulletin pape
Impact of head and neck volume reduction on prescribed dose in patients with oropharyngeal and hypopharyngeal cancer using the tomotherapy system
Get PDFThis study retrospectively examined the effects of head and neck volume reduction （external volume loss, EVL） on prescribed doses in 31 patients with oropharyngeal and hypopharyngeal cancer receiving curative intensity-modulated radiation therapy （IMRT） using the Tomotherapy system. This study focused on the relationship between treatment duration and EVL, differences in EVL between cases, and dose variation rates associated with EVL and other dosimetric indicators. To evaluate computed tomography （CT） volume data used in treatment planning （IMGplan） and mega-voltage CT images taken during treatment （IMGMV）, deformable image registration （DIR） was employed. This study noted a statistically significant moderate correlation between treatment duration and EVL, with head and neck volume decreasing at a rate of 0.09％ per day （r＝0.4515, p＜0.0001）. EVL varied by case, ranging from an average of 10.6％ to cases with little variation. Regarding EVL-related dose variation rates, the median EVL of 6.5％ led to a 1.3％ increase in dose at D0.03cc for planning target volume_highrisk but only a 0.3％ change in Dmax for Spinal cord_PRV （r＝0.5101, 0.0251; p＜0.0001, 0.4038）. This study emphasizes the significance of replanning treatments on the basis of volume changes during radiation therapy and suggests that using DIR technology for longitudinal dose assessments could be a critical practical tool for improving treatment precision. In future works, evaluating the impact of volume changes for each patient and determining the optimal timing for treatment replanning will be crucial for further improving patient outcomes.departmental bulletin pape
Changes in chronic disease medications after admission to a Geriatric Health Services Facility: A multi-center prospective cohort study
Get PDF昭和大学博士(薬学)2023年度doctoral thesi
Particle size analysis in aerosol-generating dental procedures using laser diffraction technique
Get PDF昭和大学博士(歯学)2023年度doctoral thesi
Metagenomic analysis of bacterial microflora in dental and atherosclerotic plaques of patients with internal carotid artery stenosis
Get PDF昭和大学博士(歯学)2023年度doctoral thesi
Survey of Primary Tooth Eruption Status of Down Syndrome in Japan: Comparison with the Japanese National Survey of Dental Diseases
Get PDF昭和大学博士(歯学)2023年度doctoral thesi
