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A rare case of signet ring cell carcinoma of the transverse colon with concentric intramural metastases
Get PDFSignet ring cell carcinoma is rarely accompanied by intramural metastases. The patient was a 76-year-old woman. A colonoscopy revealed early malignancy on the right side of the transverse colon. A depressed lesion was observed near the tumor. After laparoscopic right hemicolectomy, histopathological examination revealed a signet ring cell carcinoma with two intramural metastases arranged concentrically. The only complication was minor anastomotic leakage, on postoperative day 8. The patient was discharged and prescribed conservative therapy. In the 15 months since the laparoscopy, she has remained healthy, without recurrence. We treated a rare case of signet ring cell carcinoma of the transverse colon that was accompanied by concentric intramural metastases.departmental bulletin pape
Improvements in activities of daily living through respiratory rehabilitation facilitated by effective management of chronic obstructive pulmonary disease: A case report
Get PDFThis case report highlights our experience implementing a procedure aimed at enhancing the ability of older patients with limited comprehension to engage in activities of daily living （ADLs） through respiratory rehabilitation involving optimized management of chronic obstructive pulmonary disease （COPD）. A 72-year-old man was admitted to Fujigaoka Rehabilitation Hospital for rehabilitation after sustaining with multiple fractures sustained after falling down an approximately 4-m flight of stairs. On admission, he presented with exertional dyspnea attributable to heart failure and pneumothorax. For inhalation therapy, umeclidinium bromide （UMEC, 62.5µg/day）/vilanterol trifenatate （VI, 25µg/day） was initially prescribed because of its simplicity and ease of use. However, the patient did not achieve an adequate inspiratory volume with this treatment. Consequently, the inhalation therapy was switched to tiotropium bromide hydrate （TIO, 5.0µg/day）/olodaterol hydrochloride （OLO, 5.0µg/day）, which despite being less userfriendly, required less inspiratory effort. During this period, inhalation exercises were administered under the direction of a physical therapist. On day 42 of hospitalization, the patient demonstrated sufficient respiratory capacity to transition back to UMEC/VI. In postdischarge followup, the patient reported no difficulties with inhaler use and no adverse effects such as tremors or palpitations related to the medication. This case underscores the importance of individualized inhalation device selection and respiratory training in the rehabilitation of older patients with complex comorbidities.departmental bulletin pape
SMTP-44D alleviates diabetic retinopathy by suppressing inflammation and oxidative stress in in vivo and in vitro models
Get PDF昭和大学博士(薬学)2024年度doctoral thesi
Oral administration of Bifidobacterium longum and Bifidobacterium infantis ameliorates cefcapene pivoxil-induced attenuation of anti-programmed cell death protein-1 antibody action in mice
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Prognostic Factors for Mortality in Patients With Autoimmune Diseases Complicated by Pneumocystis Pneumonia
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MHC class I polypeptide-related sequence B shedding modulates pancreatic tumor immunity via the activation of NKG2DLow T cells
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Remimazolam anesthesia in pediatric patients undergoing cardiac catheterization for congenital heart disease: a retrospective observational study
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