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Doğal aydınlatma performansının LEED ölçütlerine göre geliştirilmesi için origami tabanlı hareketli cephe bileşeninin kullanılması: İYTE İnovasyon Merkezi Örneği
No full textThesis (Master)--Izmir Institute of Technology, Architecture, Izmir, 2020Includes bibliographical references (leaves: 113-118)Text in English; Abstract: Turkish and EnglishNovel solutions in sustainable design due to advancing technology are increased besides bringing new problems. One major problem is originated with the usage of fully-glazed surfaces on the building facade without any justification. Fully-glazed facades may lead to higher energy consumption and visual discomfort. In such office buildings where most of the working time is in the daytime, this situation causes a decreasing in employees' performance and high energy usage. Kinetic facades have emerged as a design solution to control daylight efficiency. Such adaptive elements with varying geometry and material can be applied to the facade according to the form, orientation, location of the building and the climate of the region. Therefore, the number of such studies must be increased. In this study, a determined part of the origami pattern (chicken wire) that consists of seven joints and six panels with a single degree of freedom as a spherical mechanism for the kinetic facade component was used. The aim is to increase daylight efficiency with three-dimensional shape changes in this kinetic facade in terms of LEED daylight criteria. IZTECH Innovation Center is modelled in Revit apply scenarios including variations of timeline, kinetic facade component's opening angles and material type. The performance of the kinetic facade is evaluated according to illuminance and sDA values calculated. As a result, a direct correlation between the customization of facade elements according to sunlight and daylight usage was observed. Findings provided us a guidance on how to apply the kinetic facade elements according to daylight.Gelişen teknolojiye bağlı olarak sürdürülebilir tasarımda yeni çözümlerle birlikle yeni sorunlar artırılmaktadır. Bina cephesinde tamamen camlı yüzeylerin herhangi bir gerekçe olmadan kullanılmasıyla önemli bir sorun ortaya çıkar. Tamamen camlı cepheler daha yüksek enerji tüketimine ve görsel rahatsızlığa neden olabilir. Çalışma süresinin çoğunun gündüz olduğu ofis binalarında, bu durum çalışanların performansında düşüşe ve yüksek enerji kullanımında neden olur. Kinetik cepheler, gün ışığı verimliliğini kontrol etmek için bir tasarım çözümü olarak ortaya çıkmıştır. Değişen geometri ve malzemeye sahip bu tür uyarlanabilir elemanlar cepheye biçim, yön, binanın yeri ve bölgenin iklimine göre uygulanabilir. Bu nedenle, bu tür çalışmaların sayısı arttırılmalıdır. Bu çalışmada, kinetik cephe bileşeni için küresel bir mekanizma olarak tek bir serbestlik derecesine sahip yedi eklem ve altı panelden oluşan origami deseninin (tavuk teli) belirli bir kısmı kullanılmıştır. Amaç, bu kinetik cephede üç boyutlu şekil değişiklikleri ile LEED gün ışığı kriterleri açısından gün ışığının verimliliğini artırmaktır. İYTE İnovasyon Merkezi Revit'de, zaman çizelgesi, kinetik cephe bileşeninin açılma açıları ve malzeme tipi çeşitlerini içeren uygulama senaryolarında modellenmiştir. Kinetik cephenin performansı, hesaplanan aydınlık ve sDA değerlerine göre değerlendirilir. Sonuç olarak, cephe elemanlarının güneş ışığına göre özelleştirilmesi ile gün ışığı kullanımı arasında doğrudan bir korelasyon gözlenmiştir. Bulgular bize kinetik cephe elemanlarının gün ışığına göre nasıl uygulanacağı konusunda rehberlik sağlamıştır
Fındıkta (Corylus avellana L.) yağ ve protein içeriği için ilişkilendirme haritalaması
No full textThesis (Master)--Izmir Institute of Technology, Molecular Biology and Genetics, Izmir, 2020Includes bibliographical references (leaves: 45-52)Text in English; Abstract: Turkish and EnglishEuropean hazelnut has an important place in terms of nutritional and economic value among tree nut species. Because of its nutritional content, the consumption of hazelnuts promotes human health in many ways. These nutritional components are controlled by multiple genes and affected by the environment; therefore, they are quantitative traits. The vast majority of world hazelnut production is provided by Turkey. So it is important to develop hazelnuts with higher nutritional quality for our country. In this work, we aimed to associate genetic diversity data and oil and protein content of hazelnuts to identify QTL. For this purpose oil and protein content were measured in kernels of 96 accessions. Genotypic data were obtained with 30 SSR markers and resulted in 407 polymorphic alleles. According to allelic data, the mean dissimilarity value was 0.52 (52%) for the 96 accessions. Population structure analysis resulted in three clusters with 30, 30, and 16 accessions. Twenty accessions could not be assigned to any cluster and were considered admixed. Association mapping between allelic and phenotypic data indicated that five loci were significantly associated with oil content. The most significant result for oil content belonged to B628-307 loci (p=0.0002, r2=0.145). Three loci were detected for protein content. Among them, A613-153 had the most significant effect (p=0.003, r2= 0.088). We hope that our survey of germplasm and the identified loci associated with oil and protein amount can accelerate hazelnut breeding. In the future this study can contribute to develop new genotypes with enhanced nutritional value.Avrupa fındığı (Corylus avellana L.) hem besin içeriği hem de ekonomik açıdan önemli bir türdür. Besin içeriği zengin olmasından dolayı, fındık tüketimi insan sağlığını birçok yönden destekler. Bu besin değerleri kantitatif özelliklerdir ve birden fazla gen tarafından kontrol edilmektedir. Dünya fındık üretiminin büyük çoğunluğu Türkiye tarafından sağlanmaktadır. Bu nedenle ülkemiz için daha yüksek besin kalitesine sahip fındıkların geliştirilmesi önemlidir. Bu çalışmadaki hedef; fındık genotiplerindeki genetik çeşitliliği, fındığın yağ ve protein içeriğindeki değişim ile ilişkilendirerek kantitatif lokusları bulmaktır. Bu amaçla 96 genotipin yağ ve protein içeriği ölçülmüştür. 30 SSR primeri kullanılarak genotipik veriler elde edilmiş ve bu analiz 407 polimorfik alel ile sonuçlanmıştır. Allelik verilere göre 96 genotipteki ortalama benzerlik değeri 0.52'dir. Popülasyon yapısı analizi sonucunda popülasyon üç kümeye ayrıldı. Küme 1 30, Küme 2 30 ve Küme 3, 16 bireye sahipti. Geriye kalan 20 genotip ise herhangi bir gruba atanamamıştır. Allelik ve fenotipik veriler arasında bir ilişki bulmak için TASSEL 2.1 yazılımı kullanılmıştır. Toplam beş lokus, yağ içeriği ile anlamlı derecede ilişkili bulunmuştur. Yağ içeriği için en önemli sonuç B628-307 lokusuna aittir (p = 0.0002, r2=0.145). Protein içerik ilişkisi için dört lokus tespit edilmiştir. Bunlar arasında en anlamlı olanı A613-153'tür (p = 0.003, r2= 0.088). Bu çalışmadan elde edilen veriler; fındıkta yağ ve protein miktarı ile ilişkili tanımlanmış lokusların fındık ıslahında kullanılması ve fındık ıslahını hızlandırması, sonuç olarak besin değeri daha yüksek fındık çeşitlerinin geliştirilmesine katkıda bulunabilecektir.Scientific and Technological Research Council of Turkey (212T201
Search for heavy Higgs bosons decaying to a top quark pair in proton-proton collisions at √s = 13 TeV
No full textA search is presented for additional scalar (H) or pseudoscalar (A) Higgs bosons decaying to a top quark pair in proton-proton collisions at a center-of-mass energy of 13 TeV. The data set analyzed corresponds to an integrated luminosity of 35.9 fb(-1) collected by the CMS experiment at the LHC. Final states with one or two charged leptons are considered. The invariant mass of the reconstructed top quark pair system and variables that are sensitive to the spin of the particles decaying into the top quark pair are used to search for signatures of the H or A bosons. The interference with the standard model top quark pair background is taken into account. A moderate signal-like deviation compatible with an A boson with a mass of 400 GeV is observed with a global significance of 1.9 standard deviations. New stringent constraints are reported on the strength of the coupling of the hypothetical bosons to the top quark, with the mass of the bosons ranging from 400 to 750 GeV and their total relative width from 0.5 to 25%. The results of the search are also interpreted in a minimal supersymmetric standard model scenario. Values of m(A) from 400 to 700 GeV are probed, and a region with values of tan beta below 1.0 to 1.5, depending on m(A), is excluded at 95% confidence level
The correlation of Magee Equations (TM) and Oncotype DX (R) recurrence score from core needle biopsy tissues in predicting response to neoadjuvant chemotherapy in ER+ and HER2- breast cancer
No full textObjective: Oncotype DX (R) recurrence score (RS) can be predicted from Magee Equations (TM) (MS) postoperatively. The aim of this study is to investigate correlation of MS with RS from pretreatment core needle biopsy (CNB) [issues, and their clinical usefulness in prediction of response to neoadjuvant chemotherapy (NCT) in estrogen receptor-positive and human epidermal growth factor receptor 2-negative (ER+/HER2-) breast cancer (BC). Materials and Methods: Prerrearmenr CNB tissue samples from 60 patients with ER+ /HER2- invasive BC were analyzed for MS and RS correlation. MS and RS were categorized as follows low (= 31). Percentage Tumor size Reduction (%TR) was used to assess tumor response to NCT, and substantial %TR was defined as at least 50% reduction (.50%TR). Correlation between MS and RS, and predictisv factors for the >= 50%TR achievement were assessed. Results: MS and RS represen red a strong correlation (Spearman's correlation; r-0.58, p= 50% TR achievemenr, none of the factors were Magically significant (p >= 0.07). Conclusion: Our study demonstrated that there was a strong correlation between MS and RS from pretreatment biopsy tissue samples in ER+ and HER2- invasive. BC
Synthesis and biological evaluation of new chloro/acetoxy substituted isoindole analogues as new tyrosine kinase inhibitors
No full textPubMed: 31759659We have developed a versatile synthetic approach for the synthesis of new isoindole derivatives via the cleavage of ethers from tricyclic imide skeleton compounds. An exo-cycloadduct prepared from the Diels-Alder reaction of furan and maleic anhydride furnished imide derivatives. The epoxide ring was opened with Ac2O or Ac2O/AcCl in the presence of a catalytic amount of H2SO4 in order to yield new isoindole derivatives 8a-d and 9a-d. The anticancer activity of these compounds was evaluated against the HeLa cell lines. The synthesized compounds showed inhibitory effects on the viability of HeLa cells and the degree of cytotoxicity was increased with the level of bigger branched isoindole derivatives. To better understand the acting mechanism of these molecules, western blot analysis was performed with using mTOR and its downstream substrates. In addition, human mTOR and ribozomal S6 kinase beta 1 (RS6K beta 1) have been investigated with molecular modelling studies as possible targets for compound series 8 and 9
Kinematic design of a non-parasitic 2R1T parallel mechanism with remote center of motion to be used in minimally invasive surgery applications
Full text linkIn minimally invasive surgery applications, the use of robotic manipulators is becoming more and more common to enhance the precision of the operations and post-operative processes. Such operations are often performed through an incision port (a pivot point) on the patient's body. Since the end-effector (the handled surgical tool) move about the pivot point, the manipulator has to move about a remote center of motion. In this study, a 3-degrees-of-freedom parallel mechanism with 2R1T (R: rotation, T: translation) remote center of motion capability is presented for minimally invasive surgery applications. First, its kinematic structure is introduced. Then, its kinematic analysis is carried out by using a simplified kinematic model which consists of three intersecting planes. Then the dimensional design is done for the desired workspace and a simulation test is carried out to verify the kinematic formulations. Finally, the prototype of the final design is presented.Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK
Function generation synthesis of planar slider-crank linkages for given 3 positions and a dead-center position
Full text linkFunction generation for finitely many positions and dead-center design problems are generally separately handled in the literature. This paper presents a mixed formulation for planar slider-crank linkages where three precision points and a folded or extended dead-center position are to be satisfied. The formulation results in an 8th degree univariate. Examples show that generally there are four real solutions, only two of which result in distinct solutions
Sitokinin sentez genini aşırı ifadeleyen domates bitkilerinin geliştirilmesi ve proteomik yaklaşımla karakterizasyonu
No full textThesis (Doctoral)--Izmir Institute of Technology, Molecular Biology and Genetics, Izmir, 2020Includes bibliographical references (leaves: 141-214)Text in English; Abstract: Turkish and EnglishCytokinins (CKs) are plant hormones controlling growth and development including cell division and differentiation, apical dominance and delay of senescence. CKs take part in regulation of the abiotic stress response in plants. In this study, transgenic tomato plants overexpressing the IPT (CK biosynthetic gene) were developed. Homozygous transgenic plants exhibited a phenotype with reduced plant stature and lost apical dominance. Increased shoot biomass and leaf water content with a reduction in fruit yield were observed in all transgenic lines. Proteomics analysis was conducted to understand high CK response in molecular level. Proteins supporting a strong sink phenotype and vasculature development were upregulated in transgenic lines and reflected the phenotypic changes observed in homozygous plants. Proteins related to stress response such as detoxification enzymes and PR proteins were upregulated in a gradual manner in transgenic lines with the strongest up-regulation in T6 homozygous line indicating the metabolic stress induced by high CK levels. The transgenic plants were tested for drought stress and observed to have improved water use efficiency, antioxidant response and delayed senescence compared to nontransgenic plants. Proteomic analyses from leaf total and nuclear enriched extracts were conducted to understand the molecular basis of improved drought tolerance. Proteins related to photosynthesis and oxidative stress response were the most prominent groups of differentially abundant proteins in the transgenic line under drought, which could contribute to tolerance. Eighteen transcription factors were differentially abundant in the nuclear proteome of drought stressed plants. These transcription factors could control the gene expression contributing to tolerance.Sitokinler (CK) hücre bölünmesi ve farklılaşması, apikaldominansi ve yaşlanmanın geciktirilmesi gibi bitki büyüme ve gelişimini kontrol eden bitki hormonlarıdır. Ayrıca bitkilerde abiyotik cevabın düzenlenmesinde de rol oynarlar. Bu çalışmada, IPT genini (CK biyosentez geni) aşırı ifade eden transgenik domates bitkileri geliştirilmiştir. Homizgot bitkilerde kısa bitki boyu ve apikal dominansın kaybı fenotipleri gözlemlenmiştir. Bütün transgenik bitkilerde yeşil aksam ağırlığında ve yaprak su miktarında artış görülürken meyve veriminin düştüğü gözlemlenmiştir. Yüksek CK tepkisinin moleküler düzeyde anlaşılması için proteomik analizler gerçekleştirilmiştir. Homozigot bitkilerdeki fenotipik değişimlere işarat edebilecek kuvvetli depo fenotipi ve iletim dokusu ile ilgili proteinlerin transgenik bitkilerde yüksek miktarda ifadelendiği tespit edilmiştir. Detoksifikasyon enzimleri ve PR proteinleri gibi stres cevabı ile iligili proteinlerin transgenik hatlarda kademeli olarak arttığı görülmüş, en fazlaartış ise T6 homozigot hattında gözlenmiştir, ki bu artış yüksek CK düzeyleri sebebi ile uyarılmış metabolik strese işaret etmektedir. Geliştirilen transgenik hatlar, kuraklık stresi için test edilmişler ve su kullanım verimi, antioksidan cevap ve geciktirilmiş yaşlanma karakteri bakımından transgenik olmayan bitkilere gore daha üsütün oldukları gözlenmiştir. Gelişmiş kuraklık toleransının moleküler düzeyde anlaşılması için yaprak total protein ve çekirdek zenginleştirilmiş özütlerinde proteomik analizler gerçekleştirilmiştir. Fotosentez ve oksidatif stres cevabı ile ilgili proteinler farklı ifadelenen proteinler arasında en öne çıkan gruplardır ve bunların kuraklık toleransı sağlanmasında etkisi olabilir. On sekiz transkripsiyon faktörünün kuraklık stresi koşulları altında farklı miktarlarda ifadelendiği tespit edilmiştir. Bu transkripsiyon faktörleri toleransa katkı sağlayan genlerin ifadelenmesini kontrol edebilirler
Gece mekanları üstüne bir araştırma: Tarihi Kemeraltı Çarşısı'nın karanlık yanını ortaya çıkarmak
No full textThesis (Master)--Izmir Institute of Technology, Architecture, Izmir, 2020Includes bibliographical references (leaves: 90-96)Text in English; Abstract: Turkish and EnglishThis thesis, with its general content, considers night and darkness as determinative factors affecting the use of space and investigates the Historical Kemeraltı Bazaar, which is chosen as the thesis area, together with the user practices. For this research, the thesis examines night spaces, darkness and user practices in the context of social space. Firstly, the concept of night spaces and darkness were examined and the spatial aspect of the night was tried to be comprehended. Accordingly, darkness has a threatening and uncertain nature and it is associated with fear. That's why it is open to a number of transgressive and illegal acts. These are such as criminal acts, provocation, rape, political opposition, subcultural practices, urban abuse, posters and graffiti etc. Secondly, night spaces and darkness are controlled by the ruling powers or classes. Surveillance is used as a means of control in urban areas with a number of techniques and technologies. Finally, night as a time that supports social practices and creates a profitable space, appears as a place of consumption and leisure activities. In addition, the practices of the users in daily life (de Certeau, 1984) and the socially produced structure of the space (Lefebvre, 1991) were examined and correlated to the night spaces. In the light of these basic concerns, the night and darkness of the Historical Kemeraltı Bazaar, the practices and social spaces created by the actors who changed and reshaped it were examined. These actors are; vehicles, shops, customers-walkers, cleaning workers, waste material pickers, peddlers, security guards, street animals, graffiti and the atmosphere of bazaar itself. The relationships between the users and the space are reinforced with the concepts of Lefebvre's social space and de Certeau's tactic and strategy. In this direction, the nights and users of Kemeraltı Bazaar were evaluated and associated with the concept of night spaces.Bu tez, genel kapsamıyla, geceyi ve karanlığı mekân kullanımını etkileyen belirleyici birer faktör olarak ele almakta ve tez alanı olarak seçilen Tarihi Kemeraltı Çarşısı bağlamında, kullanıcı pratikleriyle birlikte incelemektedir. Bu araştırma için tez, gece mekanlarını, karanlığı ve kullanıcı eylemlerini sosyal alan bağlamında inceler. Öncelikle, gece mekanları konsepti ve karanlık incelenerek gecenin mekansal yönü anlaşılmaya çalışılmıştır. Buna göre karanlığın tehdit edici ve belirsiz bir doğası vardır ve korkuyla ilişkilendirilir. Bu yüzden bir dizi transgresif ve yasa dışı eyleme açıktır. Bunlar, suç eylemleri, provokasyon, tecavüz, siyasi muhalefet, alt kültür eylemleri, kentsel alanı kötüye kullanma, posterler ve grafiti vb. gibi eylemlerdir. İkinci olarak, gece mekanları ve karanlık, yönetici erk veya sınıflar tarafından kontrol altında tutulmaya çalışılır. Gözetleme, birtakım teknikler ve teknolojiler ile kentsel alanda kontrol aracı olarak kullanılır. Son olarak, sosyal pratikleri destekleyen ve karlı bir alan yaratan bir zaman olarak gece, tüketim ve etkinlik yeri olarak karşımıza çıkar. Ayrıca kullanıcıların günlük yaşam içindeki pratikleri (de Certeau, 1984) ve mekânın sosyal olarak üretilen yapısı (Lefebvre, 1991) incelenerek gece mekanlarıyla ilişkilendirilmiştir. Bu temel kaygılar ışığında, Tarihi Kemeraltı Çarşısı'nın geceleri ve karanlığı, onu değiştiren ve yeniden şekillendiren aktörlerin pratikleri ve yarattıkları sosyal mekanlar incelenmiştir. Bu aktörler; araçlar, dükkanlar, müşteriler ve yayalar, temizlik işçileri, atık malzeme toplayıcıları, seyyar satıcılar, güvenlik görevlileri, sokak hayvanları, duvar yazıları ve çarşının kendi atmosferidir. Kullanıcılar ve mekân arasındaki ilişkiler, Lefebvre'nin sosyal mekânı ve De Certeau'nun taktik ve stratejisi kavramları ile pekiştirilmiştir. Bu doğrultuda Kemeraltı Çarşısı'nın geceleri ve kullanıcıları değerlendirilerek gece mekanları konseptiyle ilişkilendirilmiştir
Study of central exclusive pi(+)pi(-) production in proton-proton collisions at root s=5.02 and 13 TeV
No full textWulz, Claudia-Elisabeth E/0000-0001-9226-5812; Di Florio, Adriano/0000-0003-3719-8041; TOPAKSU, Aysel KAYIS/0000-0001-5819-6913; Steggemann, Jan/0000-0003-4420-5510; Lezki, Samet/0000-0002-6909-774X; Azarkin, Maxim/0000-0002-7448-1447; Boimska, Bozena/0000-0002-4200-1541; Veckalns, Viesturs/0000-0003-3676-9711; Lopez, Oscar Gonzalez/0000-0002-4532-6464; D'Hondt, Jorgen/0000-0002-9598-6241; Tcherniaev, Evgueni/0000-0002-3685-0635; Ligabue, Franco/0000-0002-1549-7107; Tiras, Emrah/0000-0002-5628-7464; Chadeeva, Marina/0000-0003-1814-1218; Yazgan, Efe/0000-0001-5732-7950; Blekman, Freya/0000-0002-7366-7098; Ferencek, Dinko/0000-0001-9116-1202; Terkulov, Adel/0000-0003-4985-3226; Ricca, Giuseppe Della/0000-0003-2831-6982; Gokbulut, Gul/0000-0002-0175-6454; Minafra, Nicola/0000-0003-4002-1888; Calligaris, Luigi/0000-0002-9951-9448; De Guio, Federico/0000-0001-5927-8865; Obertino, Maria Margherita/0000-0002-8781-8192; Stahl, Achim/0000-0002-8369-7506; Da Silveira, Gustavo Gil/0000-0003-3514-7056; Arneodo, Michele/0000-0002-7790-7132; Fallavollita, Francesco/0000-0003-2315-2499; Cuevas-Maestro, Francisco Javier/0000-0001-5080-0821; de Souza Sandro, Fonseca/0000-0001-7830-0837; Mahmoud, Mohammed Attia/0000-0001-8692-5458; Cortezon, Jose Enrique Palencia/0000-0001-8264-0287; Ivanchenko, Vladimir N/0000-0002-1844-5433; Demiroglu, Zuhal Seyma/0000-0001-7977-7127; Demiroglu, Zuhal Seyma/0000-0001-7977-7127; Ivanchenko, Vladimir/0000-0002-1844-5433; Goh, Junghwan/0000-0002-1129-2083; Loukas, Dimitris/0000-0002-7431-3857; Iglesias, Maria Cruz Fouz/0000-0003-2950-976X; mohammed, yasser/0000-0001-8399-3017; Guler, Y./0000-0001-7598-5252; Bagliesi, Giuseppe/0000-0003-4298-1620; Meridiani, Paolo/0000-0002-8480-2259; Battilana, Carlo/0000-0002-3753-3068; Bortignon, Pierluigi/0000-0002-5360-1454; Bartosik, Nazar/0000-0002-7196-2237; Andreev, Vladimir F/0000-0002-5492-6920; Duarte, Javier/0000-0002-5076-7096; Malawski, Maciej/0000-0001-6005-0243; Benitez, Jose Feliciano/0000-0002-2633-6712; Delaere, Christophe/0000-0001-8707-6021; Canelli, Florencia/0000-0001-6361-2117; Belyaev, Alexander/0000-0002-1733-4408; Hamel de Monchenault, Gautier/0000-0002-3872-3592; Tholen, Heiner/0000-0002-2299-2421; Vormwald, Benedikt/0000-0003-2607-7287; Viliani, Lorenzo/0000-0002-1909-6343; Zevi Della Porta, Giovanni/0000-0003-0495-6061; Vartak, Adish/0000-0003-1507-1365; Zhang, Zhicai/0000-0002-1630-0986; Ruiz Jimeno, Alberto/0000-0002-3639-0368; Hall, Geoffrey/0000-0002-6299-8385; Vami, Tamas Almos/0000-0002-0959-9211; Tavolaro, Vittorio Raoul/0000-0003-2518-7521; Forthomme, Laurent/0000-0002-3302-336X; Raidal, Martti/0000-0001-7040-9491; Pieri, Marco/0000-0003-3303-6301; Lethuillier, Morgan/0000-0001-6185-2045; Lawhorn, Jay/0000-0002-8597-9259; Autermann, Christian/0000-0002-0057-0033; Li, Qiang/0000-0002-8290-0517; Gerosa, Raffaele/0000-0001-8359-3734; Paulini, Manfred/0000-0002-6714-5787; Sharma, Varun/0000-0003-1287-1471; David, Pieter/0000-0001-9260-9371; Kasemann, Matthias/0000-0002-0429-2448; Everaerts, Pieter/0000-0003-3848-324X; Manca, Elisabetta/0000-0001-8946-655X; Govoni, Pietro/0000-0002-0227-1301; Ptochos, Fotios/0000-0002-3432-3452; Chauhan, Shubhanshu/0000-0002-6544-5794; Malik, Sudhir/0000-0002-6356-2655; Ricci-Tam, Francesca/0000-0001-9750-7702; Brigljevic, Vuko/0000-0001-5847-0062; Snoeys, Walter/0000-0003-3541-9066; Shchutska, Lesya/0000-0003-0700-5448; Piperov, Stefan/0000-0002-9266-7819; Chapon, Emilien/0000-0001-6968-9828; Ivanov, Andrew/0000-0002-9270-5643; Benato, Lisa/0000-0001-5135-7489; Fernandez Perez Tomei, Thiago Rafael/0000-0002-1809-5226; Wang, Dayong/0000-0002-9013-1199; Bachiller, IreneBachiller/0000-0002-3721-4876; Robert, Schoefbeck/0000-0002-2332-8784; Mundim, Luiz/0000-0001-9964-7805; Saka, Halil/0000-0001-7616-2573; Monaco, Vincenzo/0000-0002-3617-2432; Garutti, Erika/0000-0003-0634-5539; Klanner, Robert/0000-0002-7004-9227; Gonzalez Caballero, Isidro/0000-0002-8087-3199; Goldstein, Joel/0000-0003-1591-6014; Gozzelino, Andrea/0000-0002-6284-1126; Vischia, Pietro/0000-0002-7088-8557; 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Schwandt, Joern/0000-0002-0052-597X; Van Onsem, Gerrit/0000-0002-1664-2337; Martinez Ruiz del Arbol, Pablo/0000-0002-7737-5121; Nguyen, Thong Q./0000-0003-3954-5131; Dominguez, Aaron/0000-0002-7420-5493; Fernandez Menendez, Javier/0000-0002-5213-3708; Cavallari, Francesca/0000-0002-1061-3877; Kim, Tae Jeong/0000-0001-8336-2434; Costa, Salvatore/0000-0001-9919-0569; Botta, Cristina/0000-0002-8072-795X; Petrucciani, Giovanni/0000-0003-0889-4726; Taylor, Lucas/0000-0002-6584-2538; Felcini, Marta/0000-0002-2051-9331; Alverson, George/0000-0001-6651-1178; Starling, Elizabeth/0000-0002-4399-7213; Kothekar, Kunal/0000-0001-5102-4326; Zorbakir, Ibrahim Soner/0000-0002-5962-2221; Rabbertz, Klaus/0000-0001-7040-9846; Konecki, Marcin/0000-0001-9482-4841; Tapper, Alexander/0000-0003-4543-864X; Giacomelli, Paolo/0000-0002-6368-7220; Lucchini, Marco Toliman/0000-0002-7497-7450; Presilla, Matteo/0000-0003-2808-7315; Bhandari, Rohan/0000-0001-5888-955X; Kyberd, Paul/0000-0002-7353-7090; Klein, Daniel/0000-0001-9143-5162; Bodek, Arie/0000-0003-0409-0341; Krammer, Manfred/0000-0003-2257-7751; Hernandez Calama, Jose Maria/0000-0001-6436-7547; Gutsche, Oliver/0000-0002-8015-9622; Ecklund, Karl/0000-0002-6976-4637; Trevisani, Nicolo/0000-0002-5223-9342; CHANG, PAO-TI/0000-0003-4064-388X; Scharf, Christian/0000-0002-0294-1205; Verweij, Marta/0000-0002-1504-3420; Wu, Zhenbin/0000-0003-2165-9501; Haller, Johannes/0000-0001-9347-7657; Ebrahimi, Aliakbar/0000-0003-4472-867X; Sanchez Navas, Sergio/0000-0001-6129-9059; CUFFIANI, Marco/0000-0003-2510-5039; Migliore, Ernesto/0000-0002-2271-5192; Tonelli, Guido Emilio/0000-0003-2606-9156; Sagir, Sinan/0000-0002-2614-5860; Kratschmer, Ilse/0000-0002-5636-9259; d'Enterria, David/0000-0002-5754-4303; Tosi, Silvano/0000-0002-7275-9193; Haddad, Yacine/0000-0003-4916-7752; Kole, Gouranga/0000-0002-3285-1497; Kiminsu, Ugur/0000-0001-6940-7800; Zucchetta, Alberto/0000-0003-0380-1172; Murillo Quijada, Javier Alberto/0000-0003-4933-2092; Schulte, Jan-Frederik/0000-0003-4421-680X; Tosi, Nicolo/0000-0002-0474-0247; Caputo, Claudio/0000-0001-7522-4808; Schonenberger, Myriam/0000-0002-6508-5776; Consuegra Rodriguez, Sandra/0000-0002-1383-1837; Ghosh, Saranya/0000-0001-6717-0803; Novaes, Sergio/0000-0003-0471-8549; Gonzalez Suarez, Rebeca/0000-0002-6126-7230; Zanetti, Marco/0000-0003-4281-4582; Moraes, Arthur/0000-0002-5157-5686; Litov, Leandar/0000-0002-8511-6883; Gandrajula, Reddy Pratap/0000-0001-9053-3182; Jafari, Abideh/0000-0001-7327-1870; Dragicevic, Marko/0000-0003-1967-6783; Grandi, Claudio/0000-0001-5998-3070; Landsberg, Greg/0000-0002-4184-9380; Dharmaraatna, Welathantri/0000-0002-6366-837X; Bloom, Kenneth/0000-0002-4272-8900; Krolikowski, Jan/0000-0002-3055-0236; Padula, Sandra S./0000-0003-3071-0559; Staiano, Amedeo/0000-0003-1803-624X; Lagarde, Francois/0000-0001-6990-0398; Keaveney, James/0000-0003-0766-5307; Rappoccio, Salvatore/0000-0002-5449-2560; Feld, Lutz/0000-0001-9813-8646; Ince Lezki, Merve/0000-0001-6907-0195PubMed: 32834020Central exclusive and semiexclusive production of pi(+)pi(-) pairs is measured with the CMS detector in proton-proton collisions at the LHC at center-of-mass energies of 5.02 and 13 TeV. The theoretical description of these non-perturbative processes, which have not yet been measured in detail at the LHC, poses a significant challenge to models. The two pions are measured and identified in the CMS silicon tracker based on specific energy loss, whereas the absence of other particles is ensured by calorimeter information. The total and differential cross sections of exclusive and semiexclusive central pi(+)pi(-) production are measured as functions of invariant mass, transverse momentum, and rapidity of the pi(+)pi(-) system in the fiducial region defined as transverse momentum p(T)(p) > 0.2GeV and pseudorapidity vertical bar eta(p)vertical bar < 2.4. The production cross sections for the four resonant channels f(0)(500), rho(0) (770), f(0)(980), and f(2)(1270) are extracted using a simple model. These results represent the first measurement of this process at the LHC collision energies of 5.02 and 13 TeV.BMBWF (Austria); FWF (Austria)Austrian Science Fund (FWF); FNRS (Belgium)Fonds de la Recherche Scientifique - FNRS; FWO (Belgium)FWO; CNPq (Brazil)National Council for Scientific and Technological Development (CNPq); CAPES (Brazil)CAPES; FAPERJ (Brazil)Carlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro (FAPERJ); FAPERGS (Brazil)Foundation for Research Support of the State of Rio Grande do Sul (FAPERGS); FAPESP (Brazil)Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP); MES (Bulgaria); CERN; CAS (China)Chinese Academy of Sciences; MoST (China)Ministry of Science and Technology, China; NSFC (China)National Natural Science Foundation of China (NSFC); COLCIENCIAS (Colombia)Departamento Administrativo de Ciencia, Tecnologia e Innovacion Colciencias; MSES (Croatia); CSF (Croatia); RPF (Cyprus); SENESCYT (Ecuador); MoER (Estonia); ERC IUT (Estonia)Estonian Research Council; PUT (Estonia); ERDF (Estonia)European Union (EU); Academy of Finland (Finland)Academy of Finland; MEC (Finland); HIP (Finland); CEA (France)French Atomic Energy Commission; CNRS/IN2P3 (France)Centre National de la Recherche Scientifique (CNRS); BMBF (Germany)Federal Ministry of Education & Research (BMBF); DFG (Germany)German Research Foundation (DFG); HGF (Germany); GSRT (Greece)Greek Ministry of Development-GSRT; NKFIA (Hungary); DAE (India)Department of Atomic Energy (DAE); DST (India)Department of Science & Technology (India); IPM (Iran); SFI (Ireland)Science Foundation Ireland; INFN (Italy)Istituto Nazionale di Fisica Nucleare (INFN); MSIP (Republic of Korea); NRF (Republic of Korea); MES (Latvia); LAS (Lithuania); MOE (Malaysia); UM (Malaysia); BUAP (Mexico); CINVESTAV (Mexico); CONACYT (Mexico)Consejo Nacional de Ciencia y Tecnologia (CONACyT); LNS (Mexico); SEP (Mexico); UASLP-FAI (Mexico); MOS (Montenegro); MBIE (New Zealand); PAEC (Pakistan); MSHE (Poland); NSC (Poland); FCT (Portugal)Portuguese Foundation for Science and Technology; JINR (Dubna); MON (Russia); RosAtom (Russia); RAS (Russia)Russian Academy of Sciences; RFBR (Russia)Russian Foundation for Basic Research (RFBR); NRC KI (Russia); MESTD (Serbia); SEIDI (Spain); CPAN (Spain); PCTI (Spain); FEDER (Spain)European Union (EU); MOSTR (Sri Lanka); Swiss Funding Agencies (Switzerland); MST (Taipei); ThEPCenter (Thailand); IPST (Thailand); STAR (Thailand); NSTDA (Thailand); TUBITAK (Turkey)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK); TAEK (Turkey)Ministry of Energy & Natural Resources - Turkey; NASU (Ukraine); STFC (United Kingdom)Science & Technology Facilities Council (STFC); DOE (USA)United States Department of Energy (DOE); NSF (USA)National Science Foundation (NSF); Marie-Curie program (European Union)European Union (EU); European Research Council (European Union)European Union (EU)European Research Council (ERC) [675440, 752730, 765710]; Horizon 2020 (European Union)European Union (EU) [675440, 752730, 765710]; Leventis Foundation; A.P. Sloan FoundationAlfred P. Sloan Foundation; Alexander von Humboldt FoundationAlexander von Humboldt Foundation; Belgian Federal Science Policy OfficeBelgian Federal Science Policy Office; Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium)Fonds de la Recherche Scientifique - FNRS; Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium)Institute for the Promotion of Innovation by Science and Technology in Flanders (IWT); F.R.S.-FNRS (Belgium) under the "Excellence of Science - EOS" - be.h projectFonds de la Recherche Scientifique - FNRS [30820817]; Beijing Municipal Science & Technology CommissionBeijing Municipal Science & Technology Commission [Z191100007219010]; Ministry of Education, Youth and Sports (MEYS) of the Czech RepublicMinistry of Education, Youth & Sports - Czech Republic; Deutsche Forschungsgemeinschaft (DFG) under Germany's Excellence StrategyGerman Research Foundation (DFG) [EXC 2121, 390833306]; Lendulet ("Momentum") Program; Janos Bolyai Research Scholarship of the Hungarian Academy of SciencesHungarian Academy of Sciences; New National Excellence Program UNKP; NKFIA (Hungary) [123842, 123959, 124845, 124850, 125105, 128713, 128786, 129058]; Council of Science and Industrial Research, IndiaCouncil of Scientific & Industrial Research (CSIR) - India; HOMING PLUS program of the Foundation for Polish Science; European Union, Regional Development FundEuropean Union (EU); Mobility Plus program of the Ministry of Science and Higher Education; National Science Center (Poland)National Science Centre, PolandNational Science Center, Poland [Harmonia 2014/14/M/ST2/00428, Opus 2014/13/B/ST2/02543, 2014/15/B/ST2/03998, 2015/19/B/ST2/02861, Sonata-bis 2012/07/E/ST2/01406]; National Priorities Research Program by Qatar National Research Fund; Ministry of Science and Education (Russia) [14.W03.31.0026]; Tomsk Polytechnic University Competitiveness Enhancement Program (Russia); "Nauka" Project (Russia) [FSWW-20200008]; Programa Estatal de Fomento de la Investigacion Cientifica y Tecnica de Excelencia Maria de Maeztu [MDM-2015-0509]; Programa Severo Ochoa del Principado de Asturias; Thalis program - EU-ESF; Aristeia program - EU-ESF; Greek NSRFGreek Ministry of Development-GSRT; Rachadapisek Sompot Fund for Postdoctoral Fellowship, Chulalongkorn University (Thailand); Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand); Kavli Foundation; Nvidia Corporation; SuperMicro Corporation; Welch FoundationThe Welch Foundation [C-1845]; Weston Havens Foundation (USA); FWO(Belgium) under the "Excellence of Science - EOS" - be.h projectFWO [30820817]We congratulate our colleagues in the CERN accelerator departments for the excellent performance of the LHC and thank the technical and administrative staffs at CERN and at other CMS institutes for their contributions to the success of the CMS effort. In addition, we gratefully acknowledge the computing centers and personnel of the Worldwide LHC Computing Grid for delivering so effectively the computing infrastructure essential to our analyses. Finally, we acknowledge the enduring support for the construction and operation of the LHC and the CMS detector provided by the following funding agencies: BMBWF and FWF (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ, FAPERGS, and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS (Colombia); MSES and CSF (Croatia); RPF (Cyprus); SENESCYT (Ecuador); MoER, ERC IUT, PUT and ERDF (Estonia); Academy of Finland, MEC, and HIP (Finland); CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece); NKFIA (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); MSIP and NRF (Republic of Korea); MES (Latvia); LAS (Lithuania); MOE and UM (Malaysia); BUAP, CINVESTAV, CONACYT, LNS, SEP, and UASLP-FAI (Mexico); MOS (Montenegro); MBIE (New Zealand); PAEC (Pakistan); MSHE and NSC (Poland); FCT (Portugal); JINR (Dubna); MON, RosAtom, RAS, RFBR, and NRC KI (Russia); MESTD (Serbia); SEIDI, CPAN, PCTI, and FEDER (Spain); MOSTR (Sri Lanka); Swiss Funding Agencies (Switzerland); MST (Taipei); ThEPCenter, IPST, STAR, and NSTDA (Thailand); TUBITAK and TAEK (Turkey); NASU (Ukraine); STFC (United Kingdom); DOE and NSF (USA). Individuals have received support from the Marie-Curie program and the European Research Council and Horizon 2020 Grant, contract Nos. 675440, 752730, and 765710 (European Union); the Leventis Foundation; the A.P. Sloan Foundation; the Alexander von Humboldt Foundation; the Belgian Federal Science Policy Office; the Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium); the Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium); the F.R.S.-FNRS and FWO(Belgium) under the "Excellence of Science - EOS" - be.h project n. 30820817; the Beijing Municipal Science & Technology Commission, No. Z191100007219010; the Ministry of Education, Youth and Sports (MEYS) of the Czech Republic; the Deutsche Forschungsgemeinschaft (DFG) under Germany's Excellence Strategy - EXC 2121 "Quantum Universe" - 390833306; the Lendulet ("Momentum") Program and the Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences, the New National Excellence Program UNKP, the NKFIA research grants 123842, 123959, 124845, 124850, 125105, 128713, 128786, and 129058 (Hungary); the Council of Science and Industrial Research, India; the HOMING PLUS program of the Foundation for Polish Science, cofinanced from European Union, Regional Development Fund, the Mobility Plus program of the Ministry of Science and Higher Education, the National Science Center (Poland), contracts Harmonia 2014/14/M/ST2/00428, Opus 2014/13/B/ST2/02543, 2014/15/B/ST2/03998, and 2015/19/B/ST2/02861, Sonata-bis 2012/07/E/ST2/01406; the National Priorities Research Program by Qatar National Research Fund; the Ministry of Science and Education, grant no. 14.W03.31.; 0026 (Russia); the Tomsk Polytechnic University Competitiveness Enhancement Program and "Nauka" Project FSWW-20200008 (Russia); the Programa Estatal de Fomento de la Investigacion Cientifica y Tecnica de Excelencia Maria de Maeztu, grant MDM-2015-0509 and the Programa Severo Ochoa del Principado de Asturias; the Thalis and Aristeia programs cofinanced by EU-ESF and the Greek NSRF; the Rachadapisek Sompot Fund for Postdoctoral Fellowship, Chulalongkorn University and the Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand); the Kavli Foundation; the Nvidia Corporation;