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Proposals for Monitoring Current Conservation Condition of Historical Masonry Buildings: Matrone Church and Çardak Han Cases
No full textBu yazının amacı, tarihsel yığma yapıların tespit ve izlenme süreciyle ilgili uluslararası gelişmelerin ulusal alana aktarılmasıdır. Seçilen yöntem, uluslararası düzeyde yapılan önerilerin ulusal vakalar üzerinde sınanması, elde edilen sonuçların karşılaştırılarak tartışılması şeklindedir. Hâlihazır analitik belgeleme sürecinde yer alan; ön çalışmalara ulaşma, yapıyı yerinde gözlemleme, ölçülü belgeleme, malzeme karakterizasyonu, haritalama ile görsel analiz aşamaları sürdürülmüştür. Ancak yapısal özellikler ve sorunların da incelenmesi vurgulanmaktadır. İlgili riskler; 2012 tarihli, UNI EN 16096 numaralı, Kültür Varlıklarının Korunması – Mimari Mirasın Durum Tespiti ve Raporlanması başlıklı standartta tanımlanan durum sınıfları dikkate alınarak değerlendirilmekte ve koruma durumuna göre müdahale öncelikleri belirlenmektedir. Ege bölgesinden, farklı hasar tip ve dağılımı içeren, farklı dönemlere ait iki tarihi yığma yapı seçilmiştir. İzmir, Çeşme, Ildırı’daki Matrone Kilisesi ve Denizli’deki Çardak Hanı’nın koruma durumu raporları hazırlanmıştır. Bu örneklemelerin sonucunda, tarihsel yığma yapıların hâlihazır koruma durumunun izlenmesinde dikkat edilmesi gerekenler belirlenmiştir. Özgün yapım özelliklerinin ve ilgili hasarların doğru kavranmasının kültür varlığı olan tarihsel yığma yapıların sürdürülmesinde önceliği vardır. Her tarihsel yığma yapı bütünü için genel bir koruma durumu sınıfı tanımlanması ve risk değerlendirmesi, Avrupa standartlarını ve mimari restorasyon alanındaki güncel gelişimleri dikkate alan ancak ülkemiz örneklerine özgü olarak geliştirilecek bir standart çerçevesinde yapılmalıdır. Böylece kültür varlıklarımızın birbirleriyle kıyaslamalı olarak hasar durumlarının değerlendirilmesi mümkün olacaktır. Müdahaleler, doğru sırada ve kapsamda, gerekli disiplinlerin katılımı ile planlanabilecektir.The aim of this study is to transfer the international developments related to the process of diagnosis and monitoring of historical masonry structures to the national area. The method chosen is to test the recommendations made at the international level on national cases and to discuss the results obtained by comparing them. A review of preliminary studies, on-site observations, measured surveys, material characterizations, mapping and visual analysis have been carried out. An examination of structural characteristics and observed failures have also been detailed. Related risks have been evaluated with criteria developed by taking into consideration condition classes defined in the UNI EN 16096, titled Conservation of Cultural Property – Condition Survey and Report of Built Cultural Heritage. According to the defined risks and classes, priorities of interventions were determined. Two historical masonry buildings which possess characteristics of different periods and present different damage types were selected: Matrone Church in Ildırı, Çeşme, İzmir and Çardak Han in Çardak, Denizli. The condition reports of the selected buildings have been prepared. The critical points in the condition reporting of historical masonry buildings were determined: accurate comprehension of the authentic structural characteristics and related failures have priority in maintaining historical masonry structures. Identification of condition class and risk assessment of each historic masonry building should be made in accordance with a standard specific to the cases of our country, but in line with the European standards and current developments in the field of architectural restoration. Thus, it will be possible to evaluate the conservation state of our masonry assets in comparison with each other. The content and priority of interventions can be well planned with the participation of the necessary disciplines
Measurements of the W boson rapidity, helicity, double-differential cross sections, and charge asymmetry in pp collisions at root s=13 TeV
No full textBortignon, Pierluigi/0000-0002-5360-1454; Soares, Mara/0000-0001-9676-6059; Tosi, Nicolo/0000-0002-0474-0247; Tholen, Heiner/0000-0002-2299-2421; Ulrich, Ralf/0000-0002-2535-402X; Shchutska, Lesya/0000-0003-0700-5448; Hernandez Calama, Jose Maria/0000-0001-6436-7547The differential cross section and charge asymmetry for inclusive W boson production at root s = 13 TeV is measured for the two transverse polarization states as a function of the W boson absolute rapidity. The measurement uses events in which a W boson decays to a neutrino and either a muon or an electron. The data sample of proton-proton collisions recorded with the CMS detector at the LHC in 2016 corresponds to an integrated luminosity of 35.9 fb(-1). The differential cross section and its value normalized to the total inclusive W boson production cross section are measured over the rapidity range vertical bar y(w)vertical bar < 2.5. In addition to the total fiducial cross section, the W boson double-differential cross section, d(2)sigma/dp(T)(l)d vertical bar eta(l)vertical bar, and the charge asymmetry are measured as functions of the charged lepton transverse momentum and pseudorapidity. The precision of these measurements is used to constrain the parton distribution functions of the proton using the next-to-leading order NNPDF3.0 set.Austrian Federal Ministry of Education, Science and Research; Austrian Science FundAustrian Science Fund (FWF); Belgian Fonds de la Recherche ScientifiqueFonds de la Recherche Scientifique - FNRS; Fonds voor Wetenschappelijk OnderzoekFWO; CAPESCAPES; FAPERJCarlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro (FAPERJ); FAPERGSFoundation for Research Support of the State of Rio Grande do Sul (FAPERGS); FAPESPFundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP); Bulgarian Ministry of Education and Science; Chinese Academy of Sciences, Ministry of Science and TechnologyChinese Academy of Sciences; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC); Colombian Funding Agency (COLCIENCIAS)Departamento Administrativo de Ciencia, Tecnologia e Innovacion Colciencias; Croatian Ministry of Science, Education and SportMinistry of Science, Education and Sports, Republic of Croatia; Croatian Science Foundation; Research and Innovation Foundation, Cyprus; Secretariat for Higher Education, Science, Technology and Innovation, Ecuador; Ministry of Education and Research; Estonian Research CouncilEstonian Research Council [PRG780, PRG803, PRG445]; European Regional Development Fund, Estonia; Academy of FinlandAcademy of Finland; Finnish Ministry of Education and Culture; Commissariat a l'Energie Atomique et aux Energies Alternatives/CEA, FranceFrench Atomic Energy Commission; Bundesministerium fur Bildung und Forschung, GermanyFederal Ministry of Education & Research (BMBF); Deutsche Forschungsgemeinschaft (DFG) under Germany's Excellence Strategy, GermanyGerman Research Foundation (DFG) [EXC 2121, 390833306]; Helmholtz-Gemeinschaft Deutscher Forschungszentren, GermanyHelmholtz Association; National Research, Development and Innovation Fund, Hungary; Department of Atomic Energy, IndiaDepartment of Atomic Energy (DAE); Science Foundation, IrelandScience Foundation Ireland; Istituto Nazionale di Fisica Nucleare, ItalyIstituto Nazionale di Fisica Nucleare (INFN); National Research Foundation (NRF), Republic of Korea (Malaysia); University of Malaya (Malaysia)Universiti Malaya; Ministry of Science of Montenegro; CONACYTConsejo Nacional de Ciencia y Tecnologia (CONACyT); UASLP-FAI; Pakistan Atomic Energy Commission; National Science Center, PolandNational Science Centre, PolandNational Science Center, Poland; JINR, Dubna; Federal Agency of Atomic Energy of the Russian Federation; Russian Foundation for Basic ResearchRussian Foundation for Basic Research (RFBR); National Research Center "Kurchatov Institute"; Ministry of Education, Science and Technological Development of Serbia; Secretaria de Estado de Investigacion, Desarrollo e Innovacion, Programa Consolider-Ingenio 2010; Plan Estatal de Investigacion Cientifica y Tecnica y de Innovacion 2017-2020, Principado de Asturias [IDI-2018-000174]; Fondo Europeo de Desarrollo Regional, SpainEuropean Union (EU); Ministry of Science, Technology and Research, Sri Lanka; ETH Board; ETH ZurichETH Zurich; PSI; SNF; UniZH; Canton Zurich; SER; Ministry of Science and Technology, Taipei; Thailand Center of Excellence in Physics; Institute for the Promotion of Teaching Science and Technology of Thailand; Special Task Force for Activating Research; National Science and Technology Development Agency of Thailand; Scientific and Technical Research Council of TurkeyTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK); Turkish Atomic Energy AuthorityMinistry of Energy & Natural Resources - Turkey; National Academy of Sciences of Ukraine; Science and Technology Facilities Council, UKScience & Technology Facilities Council (STFC); US Department of EnergyUnited States Department of Energy (DOE); US National Science FoundationNational Science Foundation (NSF); Marie Curie programEuropean Union (EU); European Research Council (European Union)European Union (EU)European Research Council (ERC); Horizon 2020 Grant (European Union)European Union (EU) [675440, 752730, 765710]; Leventis Foundation; A. P. Sloan FoundationAlfred P. Sloan Foundation; Alexander von Humboldt FoundationAlexander von Humboldt Foundation; Belgian Federal Science Policy OfficeBelgian Federal Science Policy Office; Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium)Fonds de la Recherche Scientifique - FNRS; Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium)Institute for the Promotion of Innovation by Science and Technology in Flanders (IWT); F. R. S.-FNRS (Belgium) under the "Excellence of Science-EOS"-be.h ProjectFonds de la Recherche Scientifique - FNRS [30820817]; FWO (Belgium) under the "Excellence of Science-EOS"-be.h ProjectFWO [30820817]; Beijing Municipal Science & Technology CommissionBeijing Municipal Science & Technology Commission [Z191100007219010]; Ministry of Education, Youth and Sports (MEYS) of the Czech RepublicMinistry of Education, Youth & Sports - Czech Republic; Lendulet ("Momentum") Program; Janos Bolyai Research Scholarship of the Hungarian Academy of SciencesHungarian Academy of Sciences; New National Excellence Program UNKP; NKFIA research Grants (Hungary) [123842, 123959, 124845, 124850, 125105, 128713, 128786, 129058]; Council of Scientific and Industrial Research, IndiaCouncil of Scientific & Industrial Research (CSIR) - India; HOMING PLUS program of the Foundation for Polish Science from European Union (Poland); Regional Development Fund (Poland); Mobility Plus program of the Ministry of Science and Higher Education (Poland); National Science Center (Poland)National Science Centre, PolandNational Science Center, Poland [Harmonia 2014/14/M/ST2/00428, Opus 2014/13/B/ST2/02543, 2014/15/B/ST2/03998, 2015/19/B/ST2/02861, Sonata-bis 2012/07/E/ST2/01406]; National Priorities Research Program by Qatar National Research Fund; Ministry of Science and Higher Education (Russia) [02.a03.21.0005]; Tomsk Polytechnic University Competitiveness Enhancement Program (Russia); "Nauka" Project (Russia) [FSWW-2020-0008]; Programa de Excelencia Maria de Maeztu; Programa Severo Ochoa del Principado de Asturias; Thalis program - EU-ESF; Aristeia program - EU-ESF; Greek NSRFGreek Ministry of Development-GSRT; Rachadapisek Sompot Fund for Postdoctoral Fellowship, Chulalongkorn University (Thailand); Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand); Kavli Foundation (USA); Nvidia Corporation (USA); SuperMicro Corporation (USA); Welch Foundation (USA)The Welch Foundation [C1845]; Weston Havens Foundation (USA); CNPqNational Council for Scientific and Technological Development (CNPq); CERN; Helsinki Institute of Physics; Institut National de Physique Nucleaire et de Physique des Particules/CNRSCentre National de la Recherche Scientifique (CNRS); General Secretariat for Research and Technology, GreeceGreek Ministry of Development-GSRT; Department of Science and Technology, IndiaDepartment of Science & Technology (India); Institute for Studies in Theoretical Physics and Mathematics, Iran; Ministry of Science, ICT and Future Planning, Republic of Korea; Ministry of Education and Science of the Republic of Latvia; Lithuanian Academy of SciencesResearch Council of Lithuania (LMTLT); Ministry of Education (Malaysia)Ministry of Education, Malaysia; BUAP; CINVESTAV; LNS; SEP; Ministry of Business, Innovation and Employment, New ZealandNew Zealand Ministry of Business, Innovation and Employment (MBIE); Ministry of Science and Higher Education, PolandMinistry of Science and Higher Education, Poland; Fundacao para a Ciencia e a Tecnologia, PortugalPortuguese Foundation for Science and Technology; Ministry of Education and Science of the Russian FederationMinistry of Education and Science, Russian Federation; Russian Academy of SciencesRussian Academy of SciencesWe congratulate our colleagues in the CERN accelerator departments for the excellent performance of the LHC and thank the technical and administrative staffs at CERN and at other CMS institutes for their contributions to the success of the CMS effort. In addition, we gratefully acknowledge the computing centers and personnel of the Worldwide LHC Computing Grid for delivering, so effectively, the computing infrastructure essential to our analyses. Finally, we acknowledge the enduring support for the construction and operation of the LHC and the CMS detector provided by the following funding agencies: the Austrian Federal Ministry of Education, Science and Research and the Austrian Science Fund; the Belgian Fonds de la Recherche Scientifique, and Fonds voor Wetenschappelijk Onderzoek; the Brazilian Funding Agencies (CNPq, CAPES, FAPERJ, FAPERGS, and FAPESP); the Bulgarian Ministry of Education and Science; CERN; the Chinese Academy of Sciences, Ministry of Science and Technology, and National Natural Science Foundation of China; the Colombian Funding Agency (COLCIENCIAS); the Croatian Ministry of Science, Education and Sport, and the Croatian Science Foundation; the Research and Innovation Foundation, Cyprus; the Secretariat for Higher Education, Science, Technology and Innovation, Ecuador; the Ministry of Education and Research, Estonian Research Council via PRG780, PRG803, and PRG445 and European Regional Development Fund, Estonia; the Academy of Finland, Finnish Ministry of Education and Culture, and Helsinki Institute of Physics; the Institut National de Physique Nucleaire et de Physique des Particules/CNRS and Commissariat a l'Energie Atomique et aux Energies Alternatives/CEA, France; the Bundesministerium fur Bildung und Forschung, the Deutsche Forschungsgemeinschaft (DFG) under Germany's Excellence Strategy-EXC 2121 "Quantum Universe"-390833306, and Helmholtz-Gemeinschaft Deutscher Forschungszentren, Germany; the General Secretariat for Research and Technology, Greece; the National Research, Development and Innovation Fund, Hungary; the Department of Atomic Energy and the Department of Science and Technology, India; the Institute for Studies in Theoretical Physics and Mathematics, Iran; the Science Foundation, Ireland; the Istituto Nazionale di Fisica Nucleare, Italy; the Ministry of Science, ICT and Future Planning, and National Research Foundation (NRF), Republic of Korea; the Ministry of Education and Science of the Republic of Latvia; the Lithuanian Academy of Sciences; the Ministry of Education, and University of Malaya (Malaysia); the Ministry of Science of Montenegro; the Mexican Funding Agencies (BUAP, CINVESTAV, CONACYT, LNS, SEP, and UASLP-FAI); the Ministry of Business, Innovation and Employment, New Zealand; the Pakistan Atomic Energy Commission; the Ministry of Science and Higher Education and the National Science Center, Poland; the Fundacao para a Ciencia e a Tecnologia, Portugal; JINR, Dubna; the Ministry of Education and Science of the Russian Federation, the Federal Agency of Atomic Energy of the Russian Federation, Russian Academy of Sciences, the Russian Foundation for Basic Research, and the National Research Center "Kurchatov Institute"; the Ministry of Education, Science and Technological Development of Serbia; the Secretaria de Estado de Investigacion, Desarrollo e Innovacion, Programa Consolider-Ingenio 2010, Plan Estatal de Investigacion Cientifica y Tecnica y de Innovacion 2017-2020, research Project No.; IDI-2018-000174 del Principado de Asturias, and Fondo Europeo de Desarrollo Regional, Spain; the Ministry of Science, Technology and Research, Sri Lanka; the Swiss Funding Agencies (ETH Board, ETH Zurich, PSI, SNF, UniZH, Canton Zurich, and SER); the Ministry of Science and Technology, Taipei; the Thailand Center of Excellence in Physics, the Institute for the Promotion of Teaching Science and Technology of Thailand, Special Task Force for Activating Research, and the National Science and Technology Development Agency of Thailand; the Scientific and Technical Research Council of Turkey, and Turkish Atomic Energy Authority; the National Academy of Sciences of Ukraine; the Science and Technology Facilities Council, UK; the US Department of Energy, and the US National Science Foundation. Individuals have received support from the Marie Curie program and the European Research Council and Horizon 2020 Grant, Contracts No. 675440, 752730, and 765710 (European Union); the Leventis Foundation; the A. P. Sloan Foundation; the Alexander von Humboldt Foundation; the Belgian Federal Science Policy Office; the Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium); the Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium); the F. R. S.-FNRS and FWO (Belgium) under the "Excellence of Science-EOS"-be.h Project No 30820817; the Beijing Municipal Science & Technology Commission, Grant No. Z191100007219010; the Ministry of Education, Youth and Sports (MEYS) of the Czech Republic; the Lendulet ("Momentum") Program and the Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences, the New National Excellence Program UNKP, the NKFIA research Grants No. 123842, 123959, 124845, 124850, 125105, 128713, 128786, and 129058 (Hungary); the Council of Scientific and Industrial Research, India; the HOMING PLUS program of the Foundation for Polish Science, cofinanced from European Union, Regional Development Fund, the Mobility Plus program of the Ministry of Science and Higher Education, the National Science Center (Poland), Contracts No. Harmonia 2014/14/M/ST2/00428, Opus 2014/13/B/ST2/02543, 2014/15/B/ST2/03998, and 2015/19/B/ST2/02861, Sonata-bis 2012/07/E/ST2/01406; the National Priorities Research Program by Qatar National Research Fund; the Ministry of Science and Higher Education, Project No. 02.a03.21.0005 (Russia); the Tomsk Polytechnic University Competitiveness Enhancement Program and "Nauka" Project No. FSWW-2020-0008 (Russia); the Programa de Excelencia Maria de Maeztu and the Programa Severo Ochoa del Principado de Asturias; the Thalis and Aristeia programs cofinanced by EU-ESF and the Greek NSRF; the Rachadapisek Sompot Fund for Postdoctoral Fellowship, Chulalongkorn University and the Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand); the Kavli Foundation; the Nvidia Corporation; the SuperMicro Corporation; the Welch Foundation, Contract No. C1845; and the Weston Havens Foundation (USA)
Fine-Tuned Spin-3/2 and the Hierarchy Problem
No full textIn the past, Kundu et al. and Chakraborty et al. used extra scalar fields to cancel the quadratic divergences in the Higgs mass squared and they determined the mass of the required scalar field. In this work, a spin-3/2 particle has been used in the same manner to nullify the power-law divergences, and it is determined that the mass of the spin-3/2 particle resides in the ball park of the GUT scale
Emülsiyon ile gözenekli SiOC+TiO2 mikronaltı/nanoküreciklerin üretimi ve karakterizasyonu
No full textThesis (Master)--Izmir Institute of Technology, Materials Science and Engineering, Izmir, 2020Includes bibliographical references (leaves: 64-75)Text in English; Abstract: Turkish and EnglishThe water resources are polluted because of the widespread use of dyes in the industry, resulting in a major ecological threat. Among the various water treatment techniques, adsorption and photocatalytic degradation methods are the most preferred owing to their easy applicability, low cost, and high efficiency. Silicon oxycarbide (SiOC), which is a type of polymer-derived ceramic, has the potential to be used in harsh environmental conditions thanks to its strong chemical stability and oxidation resistance, that being said it can also be used as a photocatalyst substrate. Titanium dioxide (TiO2) photocatalysts are extensively used for purification of contaminated waters. And also, TiO2 particles are synthesized with various material groups to investigate the adsorption and photocatalytic effect. In this thesis, initially, submicron/nano SiOC spheres were produced via an oil in water (o/w) emulsion technique by using parameters such as two types of preceramic polymer precursors (silicon oil and resin), mixing types (magnetically and ultrasonically), and different pyrolysis temperature (600-1200 oC). Upon the formation of submicron/nano SiOC spheres, selected samples were impregnated with a different molar of titanium oxide precursor solution (Titanium(IV) n-butoxide (TBT)) and calcined at 450 °C for 4 h. Various amounts of (0-5-10-20 wt.%) TiO2 containing submicron/nano SiOC spheres were produced and then characterized in depth by various techniques. Finally, the effects of pyrolysis temperatures and the amount of TiO2 were investigated in terms of adsorption and photocatalytic performance against aqueous cationic dye (methylene blue) (MB) solution. In the adsorption experiments, pure SiOC submicron/nanospheres (UM1200), pyrolyzed at 1200 oC, showed the best performance at the end of 24 h in the dark with 64% adsorption. In photocatalytic experiments, samples obtained by coating the SiOC substrate produced by pyrolysis at 600 oC with different amounts of TiO2 (UM600T5, UM600T10 and UM600T20) showed 79%, 80%, and 87% photodegradation efficiency.Boyaların endüstride yaygın olarak kullanılması su kaynaklarında kirliliğe neden olmaktadır ve bu da büyük bir ekolojik tehdit oluşturmaktadır. Çeşitli su arıtma teknikleri arasında, adsorpsiyon ve fotokatalitik bozunma yöntemleri kolay uygulanabilirliği, düşük maliyeti ve yüksek verimliliği sayesinde en çok tercih edilenlerdir. Polimer türevli bir seramik türü olan silikon oksikarbür (SiOC), güçlü kimyasal stabilitesi ve oksidasyon direnci sayesinde sert çevre koşullarında kullanılma potansiyeline sahiptir ve bu sayede bir fotokatalist substratı olarak da kullanılabileceği söylenilebilir. Titanyum dioksit (TiO2) fotokatalistleri, kirli suların temizlenmesi için yaygın olarak kullanılmaktadır. Ayrıca TiO2 partikülleri, adsorpsiyon ve fotokatalitik etkiyi araştırmak için çeşitli malzeme grupları ile sentezlenmektedir. Bu tezde, ilk olarak, micron-altı/nano SiOC küreler, iki tip öncü preseramik polimeri (silikon yağı ve reçine), karıştırma tipleri (manyetik ve ultrasonik) ve farklı piroliz sıcaklıkları (600-1200 oC) gibi parametreler kullanılarak su içinde yağ (o / w) emülsiyon tekniği ile üretilmiştir. Mikron-altı/nano SiOC kürelerinin elde edilmesi üzerine seçilmiş numuneler farklı molaritelerde titanyum oksit öncü çözeltisi (Titanyum (IV) n-butoksit (TBT)) ile emdirme işlemine ve 450 ° C'de 4 saat kalsinasyona tabi tutulmuştur. Çeşitli miktarlarda (ağırlıkça% 0-5-10-20) TiO2 içeren micron-altı/nano SiOC küreleri üretilmiş ve çeşitli tekniklerle derinlemesine karakterize edilmiştir. Son olarak, piroliz sıcaklıklarının ve TiO2 miktarının etkisi sulu katyonik boya (metilen mavisi) (MB) çözeltisine karşı adsorpsiyon ve fotokatalitik performans açısından araştırılmıştır. Adsorpsiyon deneylerinde, 1200 oC'de pirolize edilerek üretilen saf SiOC micron-altı/nanoküreleri (UM1200), 24 saat sonunda %64 adsorpsiyon ile en iyi performansı göstermiştir. Fotokatalitik deneylerde ise, 600 °C' de pirolize edilerek üretilen SiOC substratının farklı miktarlarda TiO2 ile kaplanması ile elde edilen numuneler (UM600T5, UM600T10 ve UM600T20) % 79, % 80 ve % 87 fotodegradasyon verimi göstermişlerdir
Listeria monocytogenes protein profillerinin kütle spektrometresi kullanılarak fenolik asitlerin varlığında incelenmesi
No full textThesis (Master)--Izmir Institute of Technology, Chemistry, Izmir, 2020Includes bibliographical references (leaves: 75-82)Text in English; Abstract: Turkish and EnglishListeria monocytogenes is one of the foodborne pathogens (FBP), which are a threat to the consumers' health, able to cause listeriosis. L. monoytgenes cells, which can easily adapt and survive stresses, can develop resistance to antibiotics used in standard therapy. Phenolic acids that are a natural defense mechanism against stress conditions in plants, might be used as an antibacterial-candidate in foodborne diseases, so there is a need for a better understanding of the stress-induced responses and mechanisms of bacteria against these substances. Proteomic approaches are an invaluable method for identifying the stress response in pathogenic bacteria. For this purpose, in this study firstly, the antibacterial effects of two phenolic acids (3-HPAA and 4-HBA) on bacteria were investigated by determining the minimum inhibitory concentrations (MIC). Subsequently, target changes in the protein profile due to antimicrobial effects of phenolic acids were evaluated using a soft ionization technology and mass spectrometry-based comparative gel-free proteomic approach (Shotgun proteomics). According to the results, Listeria monocytogenes could not develop resistance to both phenolic acids. This study emphasizes the importance of using of phenolic acids as a novel and natural therapy methods to overcome antibiotic-resistant pathogenic bacteria.Listeria monocytogenes, tüketicilerin sağlığını tehdit eden ve listeriosis'e neden olabilen gıda kaynaklı patojenlerden (FBP) biridir. Stresleri kolayca adapte edebilen ve hayatta kalabilen L. monoytgenes hücreleri, standart tedavide kullanılan antibiyotiklere direnç geliştirebilir. Bitkilerdeki stres koşullarına karşı doğal bir savunma mekanizması olan fenolik asitler, gıda kaynaklı hastalıklarda antibakteriyel bir aday olarak kullanılabilir, dolayısıyla bakterilerin bu maddelere karşı stres kaynaklı tepkilerinin ve mekanizmalarının daha iyi anlaşılmasına ihtiyaç vardır. Proteomik yaklaşımlar, patojenik bakterilerdeki stres tepkisini tanımlamak için paha biçilmez bir yöntemdir. Bu amaçla, bu çalışmada öncelikle, iki fenolik asidin bakteriler üzerindeki antibakteriyel etkileri, minimum inhibitör konsantrasyonları (MIC) belirlenerek araştırılmıştır. Daha sonra, fenolik asitlerin antimikrobiyal etkilerine bağlı olarak protein profilindeki hedef değişiklikler yumuşak bir iyonizasyon teknolojisi ve kütle spektrometrisine dayalı karşılaştırmalı jel içermeyen proteomik yaklaşım (av tüfeği proteomik) kullanılarak değerlendirildi. Sonuçlara göre, Listeria monocytogenes her iki fenolik aside karşı direnç geliştiremedi. Bu çalışma, antibiyotiğe dirençli patojenik bakterilerin üstesinden gelmek için fenolik asitlerin yeni ve doğal bir tedavi yöntemi olarak kullanılmasının önemini vurgulamaktadır
Observation of the production of three massive gauge bosons at √s=13 TeV
No full textPubMed: 33095594The first observation is reported of the combined production of three massive gauge bosons (VVV with V = W, Z) in proton-proton collisions at a center-of-mass energy of 13 TeV. The analysis is based on a data sample recorded by the CMS experiment at the CERN LHC corresponding to an integrated luminosity of 137 fb(-1). The searches for individualWWW, WWZ, WZZ, and ZZZ production are performed in final states with three, four, five, and six leptons (electrons or muons), or with two same-sign leptons plus one or two jets. The observed (expected) significance of the combinedVVV production signal is 5.7 (5.9) standard deviations and the corresponding measured cross section relative to the standard model prediction is 1.02(-0.23)(+0.26). The significances of the individual WWW and WWZ production are 3.3 and 3.4 standard deviations, respectively. Measured production cross sections for the individual triboson processes are also reported
Measurement of the top quark Yukawa coupling from t(t)over-bar kinematic distributions in the dilepton final state in proton-proton collisions at root s=13 TeV
No full textTosi, Nicolo/0000-0002-0474-0247; Bortignon, Pierluigi/0000-0002-5360-1454; Hernandez Calama, Jose Maria/0000-0001-6436-7547; Polikarpov, Sergey/0000-0001-6839-928X; Soares, Mara/0000-0001-9676-6059; mohammed, yasser/0000-0001-8399-3017; Lotfy Abdelfattah Ahmad, Ahmad/0000-0003-4681-0079; Ulrich, Ralf/0000-0002-2535-402XA measurement of the Higgs boson Yukawa coupling to the top quark is presented using proton-proton collision data at root s = 13 TeV, corresponding to an integrated luminosity of 137 fb(-1), recorded with the CMS detector. The coupling strength with respect to the standard model value, Y-t, is determined from kinematic distributions in t (t) over bar final states containing ee, mu mu, or e mu pairs. Variations of the Yukawa coupling strength lead to modified distributions for t (t) over bar production. In particular, the distributions of the t (t) over bar mass of the a system and the rapidity difference of the top quark and antiquark are sensitive to the value of Y-t. The measurement yields a best fit value of Y-t = 1.16(-0.35)(+0.24), bounding Y-t < 1.54 at a 95% confidence level.BMBWF (Austria); FWF (Austria)Austrian Science Fund (FWF); FNRS (Belgium)Fonds de la Recherche Scientifique - FNRS; FWO (Belgium)FWO; CNPq (Brazil)National Council for Scientific and Technological Development (CNPq); CAPES (Brazil)CAPES; FAPERJ (Brazil)Carlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro (FAPERJ); FAPERGS (Brazil)Foundation for Research Support of the State of Rio Grande do Sul (FAPERGS); FAPESP (Brazil)Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP); MES (Bulgaria); CERN; CAS (China)Chinese Academy of Sciences; MoST (China)Ministry of Science and Technology, China; NSFC (China)National Natural Science Foundation of China (NSFC); COLCIENCIAS (Colombia)Departamento Administrativo de Ciencia, Tecnologia e Innovacion Colciencias; MSES (Croatia); CSF (Croatia); RIF (Cyprus); SENESCYT (Ecuador); MoER (Estonia); ERC IUT (Estonia)Estonian Research Council; PUT (Estonia); ERDF (Estonia)European Union (EU); Academy of Finland (Finland)Academy of Finland; MEC (Finland); HIP (Finland); CEA (France)French Atomic Energy Commission; CNRS/IN2P3 (France)Centre National de la Recherche Scientifique (CNRS); BMBF (Germany)Federal Ministry of Education & Research (BMBF); DFG (Germany)German Research Foundation (DFG); HGF (Germany); GSRT (Greece)Greek Ministry of Development-GSRT; NKFIA (Hungary); DAE (India)Department of Atomic Energy (DAE); DST (India)Department of Science & Technology (India); IPM (Iran); SFI (Ireland)Science Foundation Ireland; INFN (Italy)Istituto Nazionale di Fisica Nucleare (INFN); MSIP (Republic of Korea); NRF (Republic of Korea); MES (Latvia); LAS (Lithuania); MOE (Malaysia); UM (Malaysia); BUAP (Mexico); CINVESTAV (Mexico); CONACYT (Mexico)Consejo Nacional de Ciencia y Tecnologia (CONACyT); LNS (Mexico); SEP (Mexico); UASLP-FAI (Mexico); MOS (Montenegro); MBIE (New Zealand); PAEC (Pakistan); MSHE (Poland); NSC (Poland); FCT (Portugal)Portuguese Foundation for Science and Technology; JINR (Dubna); MON (Russia); RosAtom (Russia); RAS (Russia)Russian Academy of Sciences; RFBR (Russia)Russian Foundation for Basic Research (RFBR); NRC KI (Russia); MESTD (Serbia); SEIDI (Spain); CPAN (Spain); PCTI (Spain); FEDER (Spain)European Union (EU); MOSTR (Sri Lanka); Swiss Funding Agencies (Switzerland); MST (Taipei); ThEPCenter (Thailand); IPST (Thailand); STAR (Thailand); NSTDA (Thailand); TUBITAK (Turkey)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK); TAEK (Turkey)Ministry of Energy & Natural Resources - Turkey; NASU (Ukraine); STFC (United Kingdom)Science & Technology Facilities Council (STFC); DOE (USA)United States Department of Energy (DOE); NSF (USA)National Science Foundation (NSF); Marie-Curie program (European Union)European Union (EU); European Research Council (European Union)European Union (EU)European Research Council (ERC); Horizon 2020Grants (European Union) [675440, 752730, 765710]; Leventis Foundation; A. P. Sloan FoundationAlfred P. Sloan Foundation; Alexander von Humboldt FoundationAlexander von Humboldt Foundation; Belgian Federal Science Policy OfficeBelgian Federal Science Policy Office; Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium)Fonds de la Recherche Scientifique - FNRS; Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium)Institute for the Promotion of Innovation by Science and Technology in Flanders (IWT); F. R. S.-FNRS (Belgium) under the "Excellence of Science-EOS"-be.h ProjectFonds de la Recherche Scientifique - FNRS [30820817]; FWO (Belgium) under the "Excellence of Science-EOS"-be.h ProjectFWO [30820817]; Beijing Municipal Science and Technology CommissionBeijing Municipal Science & Technology Commission [Z191100007219010]; Ministry of Education, Youth and Sports (MEYS) of the Czech RepublicMinistry of Education, Youth & Sports - Czech Republic; Deutsche Forschungsgemeinschaft (DFG) under Germany's Excellence StrategyGerman Research Foundation (DFG) [EXC 2121, 390833306]; Lendulet ("Momentum") Program (Hungary); Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences (Hungary); New National Excellence Program UNKP (Hungary); NKFIA research Grants (Hungary) [123842, 123959, 124845, 124850, 125105, 128713, 128786, 129058]; National Priorities Research Program by Qatar National Research Fund; Ministry of Science and Higher Education (Russia) [02.a03.21.0005]; Tomsk Polytechnic University Competitiveness Enhancement Program; Programa Estatal de Fomento de la Investigacion Cientifica y Tecnica de Excelencia Maria de Maeztu [MDM-20150509]; Programa Severo Ochoa del Principado de Asturias; Thalis program - EU-ESF; Aristeia program - EU-ESF; Greek NSRFGreek Ministry of Development-GSRT; Rachadapisek Sompot Fund for Postdoctoral Fellowship, Chulalongkorn University (Thailand); ChulalongkornAcademic into Its 2ndCenturyProject Advancement Project (Thailand); Graduate Research Fellowship Program of the National Science Foundation [DGE-141911]; Kavli Foundation (USA); Nvidia Corporation (USA); SuperMicro Corporation (USA); Welch Foundation (USA)The Welch Foundation [C-1845]; Weston Havens Foundation (USA)We congratulate our colleagues in the CERN accelerator departments for the excellent performance of the LHC and thank the technical and administrative staffs at CERN and at other CMS institutes for their contributions to the success of the CMS effort. In addition, we gratefully acknowledge the computing centers and personnel of the Worldwide LHC Computing Grid for delivering so effectively the computing infrastructure essential to our analyses. Finally, we acknowledge the enduring support for the construction and operation of the LHC and the CMS detector provided by the following funding agencies: BMBWF and FWF (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ, FAPERGS, and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS (Colombia); MSES and CSF (Croatia); RIF (Cyprus); SENESCYT (Ecuador); MoER, ERC IUT, PUT and ERDF (Estonia); Academy of Finland, MEC, and HIP (Finland); CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece); NKFIA (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); MSIP and NRF (Republic of Korea); MES (Latvia); LAS (Lithuania); MOE and UM (Malaysia); BUAP, CINVESTAV, CONACYT, LNS, SEP, and UASLP-FAI (Mexico); MOS (Montenegro); MBIE (New Zealand); PAEC (Pakistan); MSHE and NSC (Poland); FCT (Portugal); JINR (Dubna); MON, RosAtom, RAS, RFBR, and NRC KI (Russia); MESTD (Serbia); SEIDI, CPAN, PCTI, and FEDER (Spain); MOSTR (Sri Lanka); Swiss Funding Agencies (Switzerland); MST (Taipei); ThEPCenter, IPST, STAR, and NSTDA (Thailand); TUBITAK and TAEK (Turkey); NASU (Ukraine); STFC (United Kingdom); DOE and NSF (USA). Individuals have received support from the Marie-Curie program and the European Research Council andHorizon 2020Grants, ContractNo. 675440, No. 752730, and No. 765710 (European Union); the Leventis Foundation; the A. P. Sloan Foundation; the Alexander von Humboldt Foundation; the Belgian Federal Science Policy Office; the Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium); the Agentschap voor Innovatie door Wetenschap en Technologie (IWTBelgium); the F. R. S.-FNRS and FWO (Belgium) under the "Excellence of Science-EOS"-be.h Project No. 30820817; the Beijing Municipal Science and Technology Commission, No. Z191100007219010; the Ministry of Education, Youth and Sports (MEYS) of the Czech Republic; the Deutsche Forschungsgemeinschaft (DFG) under Germany's Excellence Strategy-EXC 2121 "Quantum Universe"-390833306; the Lendulet ("Momentum") Program and the Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences, the New National Excellence Program UNKP, the NKFIA research Grants No. 123842, No. 123959, No. 124845, No. 124850, No. 125105, No. 128713, No. 128786, and No. 129058 (Hungary); the Council of Science and Industrial Research, India; the HOMING PLUS program of the Foundation for Polish Science, cofinanced from European Union, Regional Development Fund, the Mobility Plus program of the Ministry of Science and Higher Education, the National Science Center (Poland), Contracts Harmonia 2014/14/M/ST2/00428, Opus 2014/13/B/ST2/02543, 2014/15/B/ST2/03998, and 2015/19/B/ST2/02861, Sonata-bis 2012/07/E/ST2/01406; the National Priorities Research Program by Qatar National Research Fund; the Ministry of Science and Higher Education, Project No. 02.a03.21.; 0005 (Russia); the Tomsk Polytechnic University Competitiveness Enhancement Program; the Programa Estatal de Fomento de la Investigacion Cientifica y Tecnica de Excelencia Maria de Maeztu, grantMDM-20150509 and the Programa Severo Ochoa del Principado de Asturias; the Thalis and Aristeia programs cofinanced by EU-ESF and the Greek NSRF; the Rachadapisek Sompot Fund for Postdoctoral Fellowship, Chulalongkorn University and the ChulalongkornAcademic into Its 2ndCenturyProject Advancement Project (Thailand); the Graduate Research Fellowship Program of the National Science Foundation, Grant No. DGE-141911; the Kavli Foundation; the Nvidia Corporation; the SuperMicro Corporation; the Welch Foundation, Contract No. C-1845; and the Weston Havens Foundation (USA)
Recent "Nation Gardens" and Historical Development of Public Green Spaces in Turkey
No full textFocusing on contemporary Turkey's "nation gardens" and the state and governmental policies to build them, this study investigated the development processes and design features of these public green spaces with respect to those from past eras of Turkey (extending to Ottoman and pre-Ottoman history) and the development of public green spaces as the state's symbolic and spatial tools. The study relied on secondary sources about public green spaces from past eras of Turkey and also on the review of online news about "nation gardens" initiated after President Erdogan's announcement in May 2018. Our findings suggested that public green spaces in Turkey have played an important role in displaying the state's power nationally and internationally as well as to transfer the state's ideologies to people and thus, to build new identities of 'citizens.' Interestingly, in sharing these intentions of past policies for public green spaces, the recent introduction of nation gardens differs from those in the 19th and 20th century. Without any emphasis on modernization goals in the western-style, recent official talks described nation gardens as a way to raise Turkey and the government's reputation both nationally and internationally, while also referring to past eras but with other characteristics as the source of "traditions" extending to today
Simple high-performance liquid chromatographic method for determination of Donepezil HCl in pharmaceutical formulations
No full textDonepezil HCl is a hydrochloride salt of a piperidine derivative acetylcholinesterase inhibitor and, it uses in treatment demantia of Alzheimer’s disease. In this study, a sensitive and rapid HPLC-UV method was developed and validated for determination of Donepezil HCl in API and tablet dosage forms. Chromatographic separation was performed using a Ace 5 C18 (5 ?m, 250 x 4.6 mm) by using isocratic phosphate buffer at pH:2.0 and acetonitrile (55:45, v/v) mobile phase was used at the rate of 1.2 mL/min. The column temperature was set at 30 ?C and the UV detection was recorded at 268 nm. The method was validated with respect to specificity, precision, accuracy, linearity, repeatability and reproducibility parameters in a concentration range of 25-125 µg/mL. The limit of detection (LOD) and limit of quantification (LOQ) were determined as 1.40 and4.20 µg/mL, respectively. The uncertainty budget of the measurement for Donepezil HCl was estiamted as 5.80 % at 95% confidence level (k = 2)
Dependence of inclusive jet production on the anti-kT distance parameter in pp collisions at √s= 13 TeV
No full textThe dependence of inclusive jet production in proton-proton collisions with a center-of-mass energy of 13 TeV on the distance parameter R of the anti-kT algorithm is studied using data corresponding to integrated luminosities up to 35.9 fb?1 collected by the CMS experiment in 2016. The ratios of the inclusive cross sections as functions of transverse momentum pT and rapidity y, for R in the range 0.1 to 1.2 to those using R = 0.4 are presented in the region 84 < pT< 1588 GeV and |y|< 2.0. The results are compared to calculations at leading and next-to-leading order in the strong coupling constant using different parton shower models. The variation of the ratio of cross sections with R is well described by calculations including a parton shower model, but not by a leading-order quantum chromodynamics calculation including nonperturbative effects. The agreement between the data and the theoretical predictions for the ratios of cross sections is significantly improved when next-to-leading order calculations with nonperturbative effects are used. [Figure not available: see fulltext.]. © 2020, The Author(s)