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Retrofit Strategies for Energy Efficiency of Historic Urban Fabric in Mediterranean Climate
No full textEnergy-efficient retrofitting of historic housing stock requires methodical approach, in-depth analysis and case-specific regulatory system, yet only limited efforts have been realized. In large scale rehabilitation projects, it is essential to develop a retrofit strategy on how to decide energy-efficient solutions for buildings providing the most energy saving in a short time. This paper presents a pilot study conducted at a neighborhood scale, consisting of 22 pre-, early-republican and contemporary residential buildings in a historic urban fabric in the Mediterranean climate. This study aims to develop an integrated approach to describe case-specific solutions for larger scale historic urban fabric. It covers the building performance simulation (BPS) model and numerical analysis to determine the most related design parameters affecting annual energy consumption. All the case buildings were classified into three main groups to propose appropriate retrofit solutions in different impact categories. Retrofit solutions were gathered into two retrofit packages, Package 1 and 2, and separately, three individual operational solutions were determined, considering a five-levelled assessment criteria of EN 16883:2017 Standard. Energy classes of case buildings were calculated based on National Building Energy Regulations. Changes in building classes were evaluated considering pre- and post-retrofit status of the buildings. For the integrated approach, the most related design parameters on annual energy consumption were specified through Pearson correlation analysis. The approach indicated that three buildings, representing each building group, can initially be retrofitted. For all buildings, while maximum energy saving was provided by Package 2 with 48.57%, minimum energy saving was obtained from Package 1 with 19.8%
Mikrodalga kaviteler ile dielektrik ölçümlerinin geliştirilmesi için nümerik ve deneysel araştırmalar
No full textThesis (Master)--Izmir Institute of Technology, Electronics and Communication Engineering, Izmir, 2020Includes bibliographical references (leaves: 50-54)Text in English; Abstract: Turkish and EnglishIn this thesis, by utilising the inverse scattering problems approach, it was tried to improve the sensitivity in measuring the dielectric constants of the materials with microwave resonator cavities. The direct problem involves measurement of frequency shift and electric field/power values. The inverse problem aims to calculate the dielectric constant with the data obtained from the direct problem. First of all, the accuracy of the rectangular and cylindrical cavities operating in the S-band in the material perturbation method was compared with simulations, and how their sensitivity changes depending on the increasing frequency and dielectric constant was observed. Afterwards, dielectric constants were calculated by measuring the frequency shifts in the scope of the direct problem with a rectangular aluminium cavity for 3 different materials at the frequency of 1.254 GHz. However, this traditional method has a high error rate especially for samples with large dielectric constant or volume. For this reason, a measurement method based on Newton-Raphson iteration approach has been proposed. This proposed method uses power or electric field measurements at a particular frequency regardless of which mode is excited in the cavity. With the help of iterations based on an initial guess, the dielectric constant could be determined more precisely. Within the scope of this thesis, the results of the simulations performed with the Newton-Raphson method were given and the effect of the change of 3 different parameters of the method on the results was observed. In these simulations, iterations were carried out using electric field values at a certain number of points around the material. Finally, with the help of the spectrum analyzer, power measurements were taken from the 7-port aluminium cavity for the direct problem and the inverse scattering problem, which aims to recalculate the dielectric constant, was solved. More accurate results were obtained with the Newton-Raphson method.Bu tezde, ters saçılma problemleri yaklaşımından faydalanarak mikrodalga rezonatör kavitelerle materyallerin dielektrik katsayılarının ölçümünde hassasiyet iyileştirilmeye çalışılmıştır. Düz problem frekanstaki kayma ve elektrik alan/güç değerlerinin ölçülmesini kapsar. Ters problem ise düz problemden elde edilen verilerle dielektrik sabitini hesaplamayı amaçlar. Öncelikle, simülasyon ortamında S bandında çalışan dikdörtgen ve silindirik kavitelerin materyal pertürbasyon yöntemindeki doğrulukları kıyaslanmış, artan frekans ve dielektrik sabitine bağlı olarak hassasiyetlerinin ne yönde değiştiği gözlemlenmiştir. Ardından, dikdörtgen bir alüminyum kavite ile 1.254 GHz frekansında 3 farklı malzeme için aynı yöntemle düz problem kapsamında frekanstaki kaymalar ölçülerek dielektrik sabitleri hesaplanmıştır. Ancak özellikle dielektrik sabiti veya hacmi büyük olan maddeler için bu geleneksel yöntem yüksek hata oranına sahiptir. Bu nedenle Newton-Raphson iterasyon yaklaşımına dayanan bir ölçüm yöntemi önerilmiştir. Önerilen bu yöntemde, kavite içinde hangi modun uyarıldığına bakmaksızın belirli bir frekanstaki güç veya elektrik alan ölçümlerinden faydalanılmaktadır. Bir başlangıç tahmininden yola çıkarak yapılan iterasyonlar yardımıyla dielektrik sabiti daha hassas bir şekilde belirlenebilmiştir. Bu tez kapsamında, Newton-Raphson yöntemi ile yapılan simülasyonların sonuçları paylaşılmış ve yönteme ait 3 farklı parametrenin değişiminin sonuçlar üzerindeki etkisi gözlemlenmiştir. Bu simülasyonlarda materyalin çevresindeki belirli sayıda noktadaki elektrik alan değerleri kullanılarak iterasyonlar gerçekleştirilmiştir. Son olarak, spektrum analizör yardımıyla 7 portlu alüminyum kaviteden düz problem için güç ölçümleri alınmış ve dielektrik sabitini yeniden hesaplamayı amaçlayan ters saçılma problemi çözülmüştür. Newton-Raphson yöntemiyle daha doğru sonuçlar elde edilmiştir
Potansiyel bir kanser belirtecinin saptanması için lokalize yüzey plazmon rezonansı esaslı biyosensör tasarımı
No full textThesis (Master)--Izmir Institute of Technology, Bioengineering, Izmir, 2020Includes bibliographical references (leaves: 44-50)Text in English; Abstract: Turkish and EnglishConventional methods for detection of cancer are invasive, expensive and not suitable for early diagnosis. Therefore, demand for simple, sensitive and rapid biosensors for detection of cancer have been enormous. Gold nanorods (GNRs) have been ideal materials for utilization in biosensors because of their exceptional optical properties. Localized surface plasmon resonance (LSPR) which is created on GNR surface can be used for the development of label-free and sensitive biosensor systems. LSPR responds to changes in the refractive index of the surroundings and this change can be observed as the shift in the maximum absorption wavelengths. In this thesis, an LSPR based GNR biosensor was developed for sensitive detection of a sialic acid as a potential cancer biomarker. For this purpose, GNRs were synthesized at around 40-50 nm in length. Afterwards, glass surfaces were coated with GNRs and functionalized with self-assembling molecules. Specific monoclonal antibodies(Ab) were conjugated to the surface. The surface modifications were characterized via contact angle, scanning electron microscope, Fourier transform infrared spectroscopy and zeta potential. Ab-functionalized glass surfaces were used to quantitatively detect specific molecular bindings via LSPR. The sensitivity of the biosensor was determined as 281 RIU/nm. The detection limit in PBS was 1 nM, while in serum it was found to be as 10 nM because of the high protein content of serum. Control experiments showed that the developed biosensor chip was selective. The proposed system is promising for early diagnosis of cancer since it can detect a potential cancer biomarker at concentrations as low as nanomolar level.Kanser teşhisi için bilinen yöntemler invaziv ve maliyeti yüksek yöntemlerdir. Ayrıca erken teşhiste başarılı olamamaktadır. Bu sebeple güvenilir, hassas ve hızlı ölçüm sağlayabilen biyosensörlere ihtiyaç artmıştır. Altın nanoçubuklar eşsiz optik ve elektriksel özellikleriyle biyosensörlerde kullanmak için ideal bir malzemedir. Altın nanoçubukların yüzeyinde oluşan lokalize yüzey plazmon rezonansı (LSPR) ile etiket gerektirmeyen ve hızlı sonuç veren, hassas biyosensörler tasarlanabilmektedir. Lokalize yüzey plazmon rezonansı ortamın kırınım indisi değişimine göre yanıt vermektedir ve bu değişim ultraviyole-görünür ışık spektroskopisinde maksimum dalgaboyundaki pik kaymalarına bakarak gözlenebilmektedir. Bu çalışmada LSPR temelli altın nanoçubuk biyosensör tasarlanmıştır. Potansiyel kanser belirteci olarak bir sialik asit molekülünün teşhisi amaçlanmıştır. Bu amaç için öncelikle altın nanoçubuklar 40-50 nm boyutlarında sentezlenmiştir. Ardından, cam yüzeyler altın nanoçubuklar ile kaplanmış ve yüzey, spesifik moleküller ile fonksiyonelleştirilmiştir ve kanser belirtecine spesifik monoklonal antikor, yüzeye bağlanmıştır. Yüzey karakterizasyonları temas açı ölçümü, taramalı elekttron mikroskobu, Fourier dönüşümlü kızılötesi spektroskopisi ve zeta potansiyeli ölçümleri ile yapılmıştır. Antikor ile fonksiyonelleştirilmiş cam yüzeylerdeki spesifik moleküler bağlanmalar kantitatif olarak LSPR ile belirlenmiştir. Biyosensörün hassasiyeti 281 nm/RIU olarak bulunmuştur. Dedeksiyon limiti tampon çözeltide 1 nM, serumda ise yüksek protein içeriği sebebiyle 10 nM olarak bulunmuştur. Biyosensörün, teşhisi amaçlanan sialik asit molekülüne karşı seçiciliği kontrol deneyleriyle gösterilmiştir. Tasarlanan biyosensör, nanomolar seviyesi gibi düşük konsantrasyonlarda ölçüm sağlayabildiğinden kanserin erken teşhisi için umut verici bir sistemdir
Reactive wetting of metallic/ceramic (Al/?-Al2 O3 ) systems: a parallel molecular dynamics simulation study
No full textThe reactive wetting process of a flat solid alumina (?-Al2 O3) ceramic surface by metallic aluminum (Al) nanodroplets with different shapes (spherical, cylindrical, and layer) is studied using parallel molecular dynamics (MD) simulations based on a variable charge MD method, with focuses on heat transfer, mass transfer, and the structure of the reactive region at the Al/?-Al2 O3 interface. We find that the diffusion of oxygen (O) atoms from the substrate into the droplet leads to the formation of a continuous layer of reaction product at the interface. The diffusion length of oxygen atoms into the spherical Al droplet is found to be ~7.3 Å, and the number density of O atoms at the ~5 top layers of the substrate decreases substantially. As a result, the structural correlations near the reactive region differ considerably from those in the solid substrate. Heat generated by the exothermic reactions in the reactive region is transferred to both the substrate and the droplet. The heat transfer is found to be sensitive to droplet shape
Search for heavy Higgs bosons decaying to a top quark pair in proton-proton collisions at root s=13 TeV
No full textBortignon, Pierluigi/0000-0002-5360-1454; Guler, Y./0000-0001-7598-5252; Ivanchenko, Vladimir N/0000-0002-1844-5433; CAKIR, Altan/0000-0002-8627-7689; Palladino, Vito/0000-0002-9786-9620; Calligaris, Luigi/0000-0002-9951-9448; Bagliesi, Giuseppe/0000-0003-4298-1620; Bartosik, Nazar/0000-0002-7196-2237; Blekman, Freya/0000-0002-7366-7098; Di Crescenzo, Antonia/0000-0003-4276-8512; Peris, Antonio Delgado/0000-0002-8511-7958; Loukas, Dimitris/0000-0002-7431-3857; Cadamuro, Luca/0000-0001-8789-610X; Stahl, Achim/0000-0002-8369-7506; Danilov, Mikhail/0000-0001-9227-5164; Ricca, Giuseppe Della/0000-0003-2831-6982; Iglesias, Maria Cruz Fouz/0000-0003-2950-976X; Cortezon, Jose Enrique Palencia/0000-0001-8264-0287; Gonzalez, Barbara Alvarez/0000-0001-7767-4810; Tcherniaev, Evgueni/0000-0002-3685-0635; Ivanchenko, Vladimir/0000-0002-1844-5433; Terkulov, Adel/0000-0003-4985-3226; Lopez, Oscar Gonzalez/0000-0002-4532-6464; Wulz, Claudia-Elisabeth E/0000-0001-9226-5812; Meridiani, Paolo/0000-0002-8480-2259; Malawski, Maciej/0000-0001-6005-0243; De La Cruz, Ivan Heredia/0000-0002-8133-6467; Fallavollita, Francesco/0000-0003-2315-2499; Tiras, Emrah/0000-0002-5628-7464; Andreev, Vladimir F/0000-0002-5492-6920; Kopnina, Helen/0000-0001-7617-2288; TOPAKSU, Aysel KAYIS/0000-0001-5819-6913; Yzquierdo, Antonio Perez-Calero/0000-0003-3036-7965; Cuevas-Maestro, Francisco Javier/0000-0001-5080-0821; Veckalns, Viesturs/0000-0003-3676-9711; Yetkin, E. Asli/0000-0002-9007-8260; Vai, Ilaria/0000-0003-0037-5032; Lezki, Samet/0000-0002-6909-774X; Tytgat, Michael G./0000-0002-3990-2074; Galati, Giuliana/0000-0001-7348-3312; Steggemann, Jan/0000-0003-4420-5510; Duarte, Javier/0000-0002-5076-7096; Ligabue, Franco/0000-0002-1549-7107; Battilana, Carlo/0000-0002-3753-3068; Boimska, Bozena/0000-0002-4200-1541; Di Florio, Adriano/0000-0003-3719-8041; Arneodo, Michele/0000-0002-7790-7132; D'Hondt, Jorgen/0000-0002-9598-6241; Ramos, Juan Pablo Fernandez/0000-0002-0122-313X; Demiroglu, Zuhal Seyma/0000-0001-7977-7127; Da Silveira, Gustavo Gil/0000-0003-3514-7056; de Souza Sandro, Fonseca/0000-0001-7830-0837; Minafra, Nicola/0000-0003-4002-1888; Barria, Patrizia/0000-0002-3924-7380; Bossini, Edoardo/0000-0002-2303-2588; Ferencek, Dinko/0000-0001-9116-1202; Yazgan, Efe/0000-0001-5732-7950; Menichelli, Mauro/0000-0002-9004-735X; Polikarpov, Sergey/0000-0001-6839-928X; Dudko, Lev/0000-0002-4462-3192; Calama, Jose Maria Hernandez/0000-0001-6436-7547; De Guio, Federico/0000-0001-5927-8865; Goh, Junghwan/0000-0002-1129-2083; Demiroglu, Zuhal Seyma/0000-0001-7977-7127; Azarkin, Maxim/0000-0002-7448-1447; Mackay, Catherine/0000-0003-4252-6740; Korenkov, Vladimir/0000-0002-2342-7862; Borgonovi, Lisa/0000-0001-8679-4443; Bachiller, IreneBachiller/0000-0002-3721-4876; Hall, Geoffrey/0000-0002-6299-8385; Kogler, Roman/0000-0002-5336-4399; Maity, Manas/0000-0002-3237-3608; Roskes, Jeffrey/0000-0001-8761-0490; Presilla, Matteo/0000-0003-2808-7315; Bansal, Sunil/0000-0003-1992-0336; Roy, Ashim/0000-0002-5622-4260; sharma, ashish/0000-0002-0688-923X; Colaleo, Anna/0000-0002-0711-6319; Lo Meo, Sergio/0000-0003-3249-9208; Doroba, Krzysztof/0000-0002-7818-2364; Paganis, Stathes/0000-0002-1950-8993; Madlener, Thomas/0000-0002-0128-6536; Murillo Quijada, Javier Alberto/0000-0003-4933-2092; Ruiz Jimeno, Alberto/0000-0002-3639-0368; GUZZI, LUCA/0000-0002-3086-8260; Navarro-Tobar, Alvaro/0000-0003-3606-1780; Bravo, Cameron/0000-0003-1102-8247; Sanchez Navas, Sergio/0000-0001-6129-9059; Krolikowski, Jan/0000-0002-3055-0236; Barnyakov, Alexander/0000-0002-8556-6622; Carrillo Montoya, Camilo/0000-0002-6245-6535; Gomez, Gervasio/0000-0002-1077-6553; Grunewald, Martin/0000-0002-5754-0388; Shopova, Mariana/0000-0001-6664-2493; Salvatico, Riccardo/0000-0002-2751-0567; Arcidiacono, Roberta/0000-0001-5904-142X; Tapper, Alexander/0000-0003-4543-864X; Scharf, Christian/0000-0002-0294-1205; Kalinowski, Artur/0000-0002-1280-5493; Puerta Pelayo, Jesus/0000-0001-7390-1457; Felcini, Marta/0000-0002-2051-9331; Moran, Dermot/0000-0002-1941-9333; OZOK, FERHAT/0000-0001-9630-7362; Kayis Topaksu, Aysel/0000-0002-3169-4573A search is presented for additional scalar (H) or pseudoscalar (A) Higgs bosons decaying to a top quark pair in proton-proton collisions at a center-of-mass energy of 13 TeV. The data set analyzed corresponds to an integrated luminosity of 35.9 fb(-1) collected by the CMS experiment at the LHC. Final states with one or two charged leptons are considered. The invariant mass of the reconstructed top quark pair system and variables that are sensitive to the spin of the particles decaying into the top quark pair are used to search for signatures of the H or A bosons. The interference with the standard model top quark pair background is taken into account. A moderate signal-like deviation compatible with an A boson with a mass of 400 GeV is observed with a global significance of 1.9 standard deviations. New stringent constraints are reported on the strength of the coupling of the hypothetical bosons to the top quark, with the mass of the bosons ranging from 400 to 750 GeV and their total relative width from 0.5 to 25%. The results of the search are also interpreted in a minimal supersymmetric standard model scenario. Values of m(A) from 400 to 700 GeV are probed, and a region with values of tan beta below 1.0 to 1.5, depending on m(A), is excluded at 95% confidence level.BMBWF (Austria); FWF (Austria)Austrian Science Fund (FWF); FNRS (Belgium)Fonds de la Recherche Scientifique - FNRS; FWO (Belgium)FWO; CNPq (Brazil)National Council for Scientific and Technological Development (CNPq); CAPES (Brazil)CAPES; FAPERJ (Brazil)Carlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro (FAPERJ); FAPERGS (Brazil)Foundation for Research Support of the State of Rio Grande do Sul (FAPERGS); FAPESP (Brazil)Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP); MES (Bulgaria); CERN; CAS (China)Chinese Academy of Sciences; NSFC (China)National Natural Science Foundation of China (NSFC); MoST (China)Ministry of Science and Technology, China; COLCIENCIAS (Colombia)Departamento Administrativo de Ciencia, Tecnologia e Innovacion Colciencias; MSES (Croatia); CSF (Croatia); RPF (Cyprus); SENESCYT (Ecuador); MoER (Estonia); ERC IUT (Estonia)Estonian Research Council; PUT (Estonia); ERDF (Estonia)European Union (EU); Academy of Finland (Finland)Academy of Finland; MEC (Finland); HIP (Finland); CEA (France)French Atomic Energy Commission; CNRS/IN2P3 (France)Centre National de la Recherche Scientifique (CNRS); BMBF (Germany)Federal Ministry of Education & Research (BMBF); DFG (Germany)German Research Foundation (DFG); HGF (Germany); GSRT (Greece)Greek Ministry of Development-GSRT; NKFIA (Hungary); DAE (India)Department of Atomic Energy (DAE); DST (India)Department of Science & Technology (India); IPM (Iran); SFI (Ireland)Science Foundation Ireland; INFN (Italy)Istituto Nazionale di Fisica Nucleare (INFN); MSIP (Republic of Korea); NRF (Republic of Korea); MES (Latvia); LAS (Lithuania); MOE (Malaysia); UM (Malaysia); BUAP (Mexico); CINVESTAV (Mexico); CONACYT (Mexico)Consejo Nacional de Ciencia y Tecnologia (CONACyT); LNS (Mexico); SEP (Mexico); UASLP-FAI (Mexico); MOS (Montenegro); MBIE (New Zealand); PAEC (Pakistan); MSHE (Poland); NSC (Poland); FCT (Portugal)Portuguese Foundation for Science and Technology; JINR (Dubna); MON (Russia); RosAtom (Russia); RAS (Russia)Russian Academy of Sciences; RFBR (Russia)Russian Foundation for Basic Research (RFBR); NRC KI (Russia); MESTD (Serbia); SEIDI (Spain); CPAN (Spain); PCTI (Spain); FEDER (Spain)European Union (EU); MOSTR (Sri Lanka); Swiss Funding Agencies (Switzerland); MST (Taipei); ThEPCenter (Thailand); IPST (Thailand); STAR (Thailand); NSTDA (Thailand); TUBITAK (Turkey)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK); TAEK (Turkey)Ministry of Energy & Natural Resources - Turkey; NASU (Ukraine); SFFR (Ukraine)State Fund for Fundamental Research (SFFR); STFC (United Kingdom)Science & Technology Facilities Council (STFC); DOE (U.S.A.)United States Department of Energy (DOE); NSF (U.S.A.)National Science Foundation (NSF); Marie-Curie program (European Union)European Union (EU); European Research Council (European Union)European Union (EU)European Research Council (ERC) [675440, 752730, 765710]; Horizon 2020 (European Union)European Union (EU) [675440, 752730, 765710]; Leventis Foundation; A.P. Sloan FoundationAlfred P. Sloan Foundation; Alexander von Humboldt FoundationAlexander von Humboldt Foundation; Belgian Federal Science Policy OfficeBelgian Federal Science Policy Office; Fonds pour la Formationa la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium)Fonds de la Recherche Scientifique - FNRS; Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium)Institute for the Promotion of Innovation by Science and Technology in Flanders (IWT); F.R.S.-FNRS (Belgium) under the "Excellence of Science - EOS"- be.h projectFonds de la Recherche Scientifique - FNRS [30820817]; FWO (Belgium) under the "Excellence of Science - EOS"- be.h projectFWO [30820817]; Beijing Municipal Science AMP; Technology CommissionBeijing Municipal Science & Technology Commission [Z181100004218003]; Ministry of Education, Youth and Sports (MEYS) of the Czech RepublicMinistry of Education, Youth & Sports - Czech Republic; Lendulet ("Momentum") Program of the Hungarian Academy of Sciences; Janos Bolyai Research Scholarship of the Hungarian Academy of SciencesHungarian Academy of Sciences; New National Excellence Program - UNKP; NKFIA (Hungary) [123842, 123959, 124845, 124850, 125105, 128713, 128786, 129058]; Council of Science and Industrial Research, IndiaCouncil of Scientific & Industrial Research (CSIR) - India; HOMING PLUS program of the Foundation for Polish Science; European Union, Regional Development FundEuropean Union (EU); Mobility Plus program of the Ministry of Science and Higher Education; National Science Center (Poland)National Science Centre, PolandNational Science Center, Poland [Harmonia 2014/14/M/ST2/00428, Opus 2014/13/B/ST2/02543, 2014/15/B/ST2/03998,, 2015/19/B/ST2/02861, Sonatabis 2012/07/E/ST2/01406]; National Priorities Research Program by Qatar National Research Fund; Ministry of Science and Education (Russia) [3.2989.2017]; Programa Estatal de Fomento de la Investigacion Cientfica y Tecnica de Excelencia Marde Maeztu [MDM-2015-0509]; Programa Severo Ochoa del Principado de Asturias; Thalis program - EU-ESF; Aristeia program - EU-ESF; Greek NSRFGreek Ministry of Development-GSRT; Rachadapisek Sompot Fund for Postdoctoral Fellowship (Thailand); Chulalongkorn University (Thailand)Chulalongkorn University; Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand); Welch FoundationThe Welch Foundation [C-1845]; Weston Havens Foundation (U.S.A.)We congratulate our colleagues in the CERN accelerator departments for the excellent performance of the LHC and thank the technical and administrative staffs at CERN and at other CMS institutes for their contributions to the success of the CMS effort. In addition, we gratefully acknowledge the computing centers and personnel of the Worldwide LHC Computing Grid for delivering so effectively the computing infrastructure essential to our analyses. Finally, we acknowledge the enduring support for the construction and operation of the LHC and the CMS detector provided by the following funding agencies: BMBWF and FWF (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ, FAPERGS, and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS (Colombia); MSES and CSF (Croatia); RPF (Cyprus); SENESCYT (Ecuador); MoER, ERC IUT, PUT and ERDF (Estonia); Academy of Finland, MEC, and HIP (Finland); CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece); NKFIA (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); MSIP and NRF (Republic of Korea); MES (Latvia); LAS (Lithuania); MOE and UM (Malaysia); BUAP, CINVESTAV, CONACYT, LNS, SEP, and UASLP-FAI (Mexico); MOS (Montenegro); MBIE (New Zealand); PAEC (Pakistan); MSHE and NSC (Poland); FCT (Portugal); JINR (Dubna); MON, RosAtom, RAS, RFBR, and NRC KI (Russia); MESTD (Serbia); SEIDI, CPAN, PCTI, and FEDER (Spain); MOSTR (Sri Lanka); Swiss Funding Agencies (Switzerland); MST (Taipei); ThEPCenter, IPST, STAR, and NSTDA (Thailand); TUBITAK and TAEK (Turkey); NASU and SFFR (Ukraine); STFC (United Kingdom); DOE and NSF (U.S.A.).r Individuals have received support from the Marie-Curie program and the European Research Council and Horizon 2020 Grant, contract Nos. 675440, 752730, and 765710 (European Union); the Leventis Foundation; the A.P. Sloan Foundation; the Alexander von Humboldt Foundation; the Belgian Federal Science Policy Office; the Fonds pour la Formationa la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium); the Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium); the F.R.S.-FNRS and FWO (Belgium) under the "Excellence of Science - EOS"- be.h project n. 30820817; the Beijing Municipal Science & Technology Commission, No. Z181100004218003; the Ministry of Education, Youth and Sports (MEYS) of the Czech Republic; the Lendulet ("Momentum") Program and the Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences, the New National Excellence Program - UNKP, the NKFIA research grants 123842, 123959, 124845, 124850, 125105, 128713, 128786, and 129058 (Hungary); the Council of Science and Industrial Research, India; the HOMING PLUS program of the Foundation for Polish Science, cofinanced from European Union, Regional Development Fund, the Mobility Plus program of the Ministry of Science and Higher Education, the National Science Center (Poland), contracts Harmonia 2014/14/M/ST2/00428, Opus 2014/13/B/ST2/02543, 2014/15/B/ST2/03998, and 2015/19/B/ST2/02861, Sonatabis 2012/07/E/ST2/01406; the National Priorities Research Program by Qatar National Research Fund; the Ministry of Science and Education, grant no. 3.2989.; 2017 (Russia); the Programa Estatal de Fomento de la Investigaci~on Cientfica y Tecnica de Excelencia Marde Maeztu, grant MDM-2015-0509 and the Programa Severo Ochoa del Principado de Asturias; the Thalis and Aristeia programs cofinanced by EU-ESF and the Greek NSRF; the Rachadapisek Sompot Fund for Postdoctoral Fellowship, Chulalongkorn University and the Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand); the Welch Foundation, contract C-1845; and the Weston Havens Foundation (U.S.A.)
DNMSO; an ontology for representing de novo sequencing results from Tandem-MS data
No full textPubMed: 33150092For the identification and sequencing of proteins, mass spectrometry (MS) has become the tool of choice and, as such, drives proteomics. MS/MS spectra need to be assigned a peptide sequence for which two strategies exist. Either database search or de novo sequencing can be employed to establish peptide spectrum matches. For database search, mzIdentML is the current community standard for data representation. There is no community standard for representing de novo sequencing results, but we previously proposed the de novo markup language (DNML). At the moment, each de novo sequencing solution uses different data representation, complicating downstream data integration, which is crucial since ensemble predictions may be more useful than predictions of a single tool. We here propose the de novo MS Ontology (DNMSO), which can, for example, provide many-to-many mappings between spectra and peptide predictions. Additionally, an application programming interface (API) that supports any file operation necessary for de novo sequencing from spectra input to reading, writing, creating, of the DNMSO format, as well as conversion from many other file formats, has been implemented. This API removes all overhead from the production of de novo sequencing tools and allows developers to concentrate on algorithm development completely. We make the API and formal descriptions of the format freely available at https://github.com/savastakan/dnmso
Search for decays of the 125 GeV Higgs boson into a Z boson and a rho or phi meson
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Gonzalez Caballero, Isidro/0000-0002-8087-3199; Marzocchi, Badder/0000-0001-6687-6214; Ince Lezki, Merve/0000-0001-6907-0195; Kim, Tae Jeong/0000-0001-8336-2434; Bhowmik, Sandeep/0000-0003-1260-973X; Novaes, Sergio/0000-0003-0471-8549; Lucchini, Marco Toliman/0000-0002-7497-7450; Krikler, Benjamin/0000-0001-9712-0030; Konecki, Marcin/0000-0001-9482-4841; Monaco, Vincenzo/0000-0002-3617-2432; Spagnolo, Paolo/0000-0001-7962-5203; Levchuk, Leonid/0000-0001-5889-7410; Sharma, Varun/0000-0003-1287-1471; Sagir, Sinan/0000-0002-2614-5860; Van Onsem, Gerrit/0000-0002-1664-2337; Kole, Gouranga/0000-0002-3285-1497; Fernandez Menendez, Javier/0000-0002-5213-3708; Bloom, Kenneth/0000-0002-4272-8900; Reis, Thomas/0000-0003-3703-6624; Pastrone, Nadia/0000-0001-7291-1979; Migliore, Ernesto/0000-0002-2271-5192; Tosi, Silvano/0000-0002-7275-9193; Cadamuro, Luca/0000-0001-8789-610X; Shevchenko, Rostyslav/0000-0002-3236-4090; Tholen, Heiner/0000-0002-2299-2421; Sosa Ricardo, Rafael Eduardo/0000-0002-2240-6699; Moon, Chang-Seong/0000-0001-8229-7829; Naimuddin, Md/0000-0003-4542-386X; Zanetti, Marco/0000-0003-4281-4582; Martelli, Arabella/0000-0003-3530-2255; Heikkila, Jaana/0000-0002-0538-1469; Zghiche, Amina/0000-0002-1178-1450; Feld, Lutz/0000-0001-9813-8646; Kayis Topaksu, Aysel/0000-0002-3169-4573; Mora Herrera, Maria Clemencia/0000-0003-3915-3170; Beaudette, Florian/0000-0002-1194-8556; Usai, Emanuele/0000-0001-9323-2107; Mundim, Luiz/0000-0001-9964-7805; Kiminsu, Ugur/0000-0001-6940-7800; Tully, Christopher/0000-0001-6771-2174; d'Enterria, David/0000-0002-5754-4303; Ghosh, Saranya/0000-0001-6717-0803; Dubinin, Mikhail/0000-0002-7766-7175Decays of the 125 GeV Higgs boson into a Z boson and a rho (0)(770) or (1020) meson are searched for using proton-proton collision data collected by the CMS experiment at the LHC at s = 13 TeV. The analysed data set corresponds to an integrated luminosity of 137 fb(-1). Events are selected in which the Z boson decays into a pair of electrons or a pair of muons, and the rho and phi mesons decay into pairs of pions and kaons, respectively. No significant excess above the background model is observed. As different polarization states are possible for the decay products of the Z boson and rho or phi mesons, affecting the signal acceptance, scenarios in which the decays are longitudinally or transversely polarized are considered. Upper limits at the 95% confidence level on the Higgs boson branching fractions into Z rho and Z phi are determined to be 1.04-1.31% and 0.31-0.40%, respectively, where the ranges reflect the considered polarization scenarios; these values are 740-940 and 730-950 times larger than the respective standard model expectations. These results constitute the first experimental limits on the two decay channels.BMBWF (Austria); FWF (Austria)Austrian Science Fund (FWF); FNRS (Belgium)Fonds de la Recherche Scientifique - FNRS; FWO (Belgium)FWO; CNPq (Brazil)National Council for Scientific and Technological Development (CNPq); CAPES (Brazil)CAPES; FAPERJ (Brazil)Carlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro (FAPERJ); FAPERGS (Brazil)Foundation for Research Support of the State of Rio Grande do Sul (FAPERGS); FAPESP (Brazil)Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP); MES (Bulgaria); CERN; CAS (China)Chinese Academy of Sciences; MoST (China)Ministry of Science and Technology, China; NSFC (China)National Natural Science Foundation of China (NSFC); COLCIENCIAS (Colombia)Departamento Administrativo de Ciencia, Tecnologia e Innovacion Colciencias; MSES (Croatia); CSF (Croatia); RIF (Cyprus); SENESCYT (Ecuador); MoER (Estonia); ERC IUT (Estonia)Estonian Research Council; PUT (Estonia); ERDF (Estonia)European Union (EU); Academy of Finland (Finland)Academy of Finland; MEC (Finland); HIP (Finland); CEA (France)French Atomic Energy Commission; CNRS/IN2P3 (France)Centre National de la Recherche Scientifique (CNRS); BMBF (Germany)Federal Ministry of Education & Research (BMBF); DFG (Germany)German Research Foundation (DFG); HGF (Germany); GSRT (Greece)Greek Ministry of Development-GSRT; NKFIA (Hungary); DAE (India)Department of Atomic Energy (DAE); DST (India)Department of Science & Technology (India); IPM (Iran); SFI (Ireland)Science Foundation Ireland; INFN (Italy)Istituto Nazionale di Fisica Nucleare (INFN); MSIP (Republic of Korea); NRF (Republic of Korea); MES (Latvia); LAS (Lithuania); MOE (Malaysia); UM (Malaysia); BUAP (Mexico); CINVESTAV (Mexico); CONACYT (Mexico)Consejo Nacional de Ciencia y Tecnologia (CONACyT); LNS (Mexico); SEP (Mexico); UASLP-FAI (Mexico); MOS (Montenegro); MBIE (New Zealand); PAEC (Pakistan); MSHE (Poland); NSC (Poland); FCT (Portugal)Portuguese Foundation for Science and Technology; JINR (Dubna); MON (Russia); RosAtom (Russia); RAS (Russia)Russian Academy of Sciences; RFBR (Russia)Russian Foundation for Basic Research (RFBR); NRC KI (Russia); MESTD (Serbia); SEIDI (Spain); CPAN (Spain); PCTI (Spain); FEDER (Spain)European Union (EU); MOSTR (Sri Lanka); Swiss Funding Agencies (Switzerland); MST (Taipei); ThEPCenter (Thailand); IPST (Thailand); STAR (Thailand); NSTDA (Thailand); TUBITAK (Turkey)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK); TAEK (Turkey)Ministry of Energy & Natural Resources - Turkey; NASU (Ukraine); STFC (United Kingdom)Science & Technology Facilities Council (STFC); DOE (U.S.A.)United States Department of Energy (DOE); NSF (U.S.A.)National Science Foundation (NSF); Marie-Curie programme (European Union)European Union (EU); European Research Council (European Union)European Union (EU)European Research Council (ERC); Horizon 2020 Grant (European Union)European Union (EU) [675440, 752730, 765710]; Leventis Foundation; A.P. Sloan FoundationAlfred P. Sloan Foundation; Alexander von Humboldt FoundationAlexander von Humboldt Foundation; Belgian Federal Science Policy OfficeBelgian Federal Science Policy Office; Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium)Fonds de la Recherche Scientifique - FNRS; Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium)Institute for the Promotion of Innovation by Science and Technology in Flanders (IWT); F.R.S.-FNRS (Belgium)Fonds de la Recherche Scientifique - FNRS [30820817]; FWO (Belgium)FWO [30820817]; Beijing Municipal Science & Technology CommissionBeijing Municipal Science & Technology Commission [Z191100007219010]; Ministry of Education, Youth and Sports (MEYS) of the Czech RepublicMinistry of Education, Youth & Sports - Czech Republic; Deutsche Forschungsgemeinschaft (DFG) under Germany's Excellence StrategyGerman Research Foundation (DFG) [EXC 2121, 390833306]; Lendulet ("Momentum") Programme (Hungary); Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences (Hungary); New National Excellence Program UNKP (Hungary); NKFIA (Hungary) [12384, 123959, 124845, 124850, 125105, 128713, 128786, 129058]; Council of Science and Industrial Research, IndiaCouncil of Scientific & Industrial Research (CSIR) - India; HOMING PLUS programme of the Foundation for Polish Science (Poland) [Harmonia 2014/14/M/ST2/00428, Opus 2014/13/B/ST2/02543, 2014/15/B/ST2/03998, 2015/19/B/ST2/02861, Sonata-bis 2012/07/E/ST2/01406]; European Union (Poland)European Union (EU) [Harmonia 2014/14/M/ST2/00428, Opus 2014/13/B/ST2/02543, 2014/15/B/ST2/03998, 2015/19/B/ST2/02861, Sonata-bis 2012/07/E/ST2/01406]; Regional Development Fund (Poland) [Harmonia 2014/14/M/ST2/00428, Opus 2014/13/B/ST2/02543, 2014/15/B/ST2/03998, 2015/19/B/ST2/02861, Sonata-bis 2012/07/E/ST2/01406]; Mobility Plus programme of the Ministry of Science and Higher Education (Poland) [Harmonia 2014/14/M/ST2/00428, Opus 2014/13/B/ST2/02543, 2014/15/B/ST2/03998, 2015/19/B/ST2/02861, Sonata-bis 2012/07/E/ST2/01406]; National Science Center (Poland)National Science Centre, PolandNational Science Center, Poland [Harmonia 2014/14/M/ST2/00428, Opus 2014/13/B/ST2/02543, 2014/15/B/ST2/03998, 2015/19/B/ST2/02861, Sonata-bis 2012/07/E/ST2/01406]; National Priorities Research Program by Qatar National Research Fund; Ministry of Science and Higher Education (Russia) [02.a03.21.0005]; Programa Estatal de Fomento de la Investigacion Cientifica y Tecnica de Excelencia Maria de Maeztu [MDM-2015-0509]; Programa Severo Ochoa del Principado de Asturias; Thalis programme - EU-ESF; Aristeia programme - EU-ESF; Greek NSRFGreek Ministry of Development-GSRT; Rachadapisek Sompot Fund for Postdoctoral Fellowship, Chulalongkorn University (Thailand); Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand); Kavli Foundation; Nvidia Corporation; SuperMicro Corporation; Welch FoundationThe Welch Foundation [C-1845]; Weston Havens Foundation (U.S.A.)We congratulate our colleagues in the CERN accelerator departments for the excellent performance of the LHC and thank the technical and administrative staffs at CERN and at other CMS institutes for their contributions to the success of the CMS effort. In addition, we gratefully acknowledge the computing centres and personnel of the Worldwide LHC Computing Grid for delivering so effectively the computing infrastructure essential to our analyses. Finally, we acknowledge the enduring support for the construction and operation of the LHC and the CMS detector provided by the following funding agencies: BMBWF and FWF (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ, FAPERGS, and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS (Colombia); MSES and CSF (Croatia); RIF (Cyprus); SENESCYT (Ecuador); MoER, ERC IUT, PUT and ERDF (Estonia); Academy of Finland, MEC, and HIP (Finland); CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece); NKFIA (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); MSIP and NRF (Republic of Korea); MES (Latvia); LAS (Lithuania); MOE and UM (Malaysia); BUAP, CINVESTAV, CONACYT, LNS, SEP, and UASLP-FAI (Mexico); MOS (Montenegro); MBIE (New Zealand); PAEC (Pakistan); MSHE and NSC (Poland); FCT (Portugal); JINR (Dubna); MON, RosAtom, RAS, RFBR, and NRC KI (Russia); MESTD (Serbia); SEIDI, CPAN, PCTI, and FEDER (Spain); MOSTR (Sri Lanka); Swiss Funding Agencies (Switzerland); MST (Taipei); ThEPCenter, IPST, STAR, and NSTDA (Thailand); TUBITAK and TAEK (Turkey); NASU (Ukraine); STFC (United Kingdom); DOE and NSF (U.S.A.).; Individuals have received support from the Marie-Curie programme and the European Research Council and Horizon 2020 Grant, contract Nos. 675440, 752730, and 765710 (European Union); the Leventis Foundation; the A.P. Sloan Foundation; the Alexander von Humboldt Foundation; the Belgian Federal Science Policy Office; the Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium); the Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium); the F.R.S.-FNRS and FWO (Belgium) under the "Excellence of Science -EOS" -be.h project n. 30820817; the Beijing Municipal Science & Technology Commission, No. Z191100007219010; the Ministry of Education, Youth and Sports (MEYS) of the Czech Republic; the Deutsche Forschungsgemeinschaft (DFG) under Germany's Excellence Strategy -EXC 2121 "Quantum Universe" -390833306; the Lendulet ("Momentum") Programme and the Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences, the New National Excellence Program UNKP, the NKFIA research grants 123842, 123959, 124845, 124850, 125105, 128713, 128786, and 129058 (Hungary); the Council of Science and Industrial Research, India; the HOMING PLUS programme of the Foundation for Polish Science, cofinanced from European Union, Regional Development Fund, the Mobility Plus programme of the Ministry of Science and Higher Education, the National Science Center (Poland), contracts Harmonia 2014/14/M/ST2/00428, Opus 2014/13/B/ST2/02543, 2014/15/B/ST2/03998, and 2015/19/B/ST2/02861, Sonata-bis 2012/07/E/ST2/01406; the National Priorities Research Program by Qatar National Research Fund; the Ministry of Science and Higher Education, project no. 02.a03.21.0005 (Russia); the Programa Estatal de Fomento de la Investigacion Cientifica y Tecnica de Excelencia Maria de Maeztu, grant MDM-2015-0509 and the Programa Severo Ochoa del Principado de Asturias; the Thalis and Aristeia programmes cofinanced by EU-ESF and the Greek NSRF; the Rachadapisek Sompot Fund for Postdoctoral Fellowship, Chulalongkorn University and the Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand); the Kavli Foundation; the Nvidia Corporation; the SuperMicro Corporation; the Welch Foundation, contract C-1845; and the Weston Havens Foundation (U.S.A.)
Evaluation of a PEG-endosome disruptive peptide conjugate as a potential doxorubicin delivery system
No full textTop, Ayben/0000-0003-0554-2506In this study, it was aimed to develop a doxorubicin (DOX) carrier system based on a PEGylated TAT-derived cell penetrating peptide (G(2)RQR(3)QR(3)G(2)S) and to investigate drug release, self-assembly and stability properties of the carrier system. In the preparation of the drug delivery system, denoted as mPEG-peptide-oxime-DOX, methoxypolyethylene glycol (mPEG) with M-n=1900 Da was used. DOX was attached to the mPEG-peptide carrier system via acid cleavable oxime bond. Control drug delivery system, lack of the peptide (mPEG-oxime-DOX) was also synthesized to assess the effect of the peptide on the physicochemical and DOX release properties of the carrier system. mPEG-oxime-DOX exhibited a pH programmed DOX release with respective % DOX release values of similar to 68% and similar to 28% at pH 5.0 and at pH 7.4 at the end of 54 h. For the mPEG-peptide-oxime-DOX, on the other hand, quite low DOX release (similar to 10-15 %) was observed for both pH values suggesting possible interactions between DOX and the peptide. Initial median size value (D50) of the mPEG-oxime-DOX was measured as similar to 24 nm, independent of pH. However, for the mPEG-peptide-oxime-DOX, quite lower D50 values (similar to 3 nm and similar to 6 nm at pH 5.0 and pH 7.4, respectively) were obtained due to the repulsions between the arginines in the peptide sequence. Sizes of both drug delivery systems, tended to increase upon incubation at physiological conditions for 1 day suggesting that longer PEG chains should be used to enhance the stability of the mPEG-peptide-oxime-DOX and mPEG-oximeDOX systems.Izmir Institute of Technology Scientific Research Projects Coordination Unit (BAP) [2017IYTE53]This project was partially supported by Izmir Institute of Technology Scientific Research Projects Coordination Unit (BAP Project Number = 2017IYTE53
Search for disappearing tracks in proton-proton collisions at root s=13 TeV
No full textDemiroglu, Zuhal Seyma/0000-0001-7977-7127; Petkov, Peicho Stoev/0000-0002-0420-9480; Cuevas-Maestro, Francisco Javier/0000-0001-5080-0821; Tiras, Emrah/0000-0002-5628-7464; Sonnadara, Upul/0000-0001-7862-2537; Yazgan, Efe/0000-0001-5732-7950; Bagliesi, Giuseppe/0000-0003-4298-1620; Ricca, Giuseppe Della/0000-0003-2831-6982; Obertino, Maria Margherita/0000-0002-8781-8192; Calligaris, Luigi/0000-0002-9951-9448; Lezki, Samet/0000-0002-6909-774X; Yzquierdo, Antonio Perez-Calero/0000-0003-3036-7965; Da Silveira, Gustavo Gil/0000-0003-3514-7056; Bossini, Edoardo/0000-0002-2303-2588; Boimska, Bozena/0000-0002-4200-1541; Habibullah, Redwan/0000-0002-3161-8300; de Souza Sandro, Fonseca/0000-0001-7830-0837; Guler, Y./0000-0001-7598-5252; Demiroglu, Zuhal Seyma/0000-0001-7977-7127; Fallavollita, Francesco/0000-0003-2315-2499; Danilov, Mikhail/0000-0001-9227-5164; Steggemann, Jan/0000-0003-4420-5510; Polikarpov, Sergey/0000-0001-6839-928X; Bartosik, Nazar/0000-0002-7196-2237; Wulz, Claudia-Elisabeth E/0000-0001-9226-5812; Gokbulut, Gul/0000-0002-0175-6454; Cortezon, Jose Enrique Palencia/0000-0001-8264-0287; TOPAKSU, Aysel KAYIS/0000-0001-5819-6913; Azarkin, Maxim/0000-0002-7448-1447; Ligabue, Franco/0000-0002-1549-7107; Sen, F. Aydogmus/0000-0003-1434-2143; Ivanchenko, Vladimir/0000-0002-1844-5433; Ivanchenko, Vladimir N/0000-0002-1844-5433; Goh, Junghwan/0000-0002-1129-2083; CAKIR, Altan/0000-0002-8627-7689; Meridiani, Paolo/0000-0002-8480-2259; Peris, Antonio Delgado/0000-0002-8511-7958; Minafra, Nicola/0000-0003-4002-1888; Tcherniaev, Evgueni/0000-0002-3685-0635; Galati, Giuliana/0000-0001-7348-3312; Stahl, Achim/0000-0002-8369-7506; Bortignon, Pierluigi/0000-0002-5360-1454; Iglesias, Maria Cruz Fouz/0000-0003-2950-976X; Malawski, Maciej/0000-0001-6005-0243; Gonzalez, Barbara Alvarez/0000-0001-7767-4810; Arneodo, Michele/0000-0002-7790-7132; De Guio, Federico/0000-0001-5927-8865; Lopez, Oscar Gonzalez/0000-0002-4532-6464; Terkulov, Adel/0000-0003-4985-3226; Vai, Ilaria/0000-0003-0037-5032; Loukas, Dimitris/0000-0002-7431-3857; Blekman, Freya/0000-0002-7366-7098; Ferencek, Dinko/0000-0001-9116-1202; Andreev, Vladimir F/0000-0002-5492-6920; Duarte, Javier/0000-0002-5076-7096; Dudko, Lev/0000-0002-4462-3192; Roskes, Jeffrey/0000-0001-8761-0490; Feld, Lutz/0000-0001-9813-8646; Tully, Christopher/0000-0001-6771-2174; Vormwald, Benedikt/0000-0003-2607-7287; Amendola, Chiara/0000-0002-4359-836X; Poudyal, Nabin/0000-0003-4278-3464; Soares, Mara/0000-0001-9676-6059; Migliore, Ernesto/0000-0002-2271-5192; Gandrajula, Reddy Pratap/0000-0001-9053-3182; Wang, Dayong/0000-0002-9013-1199; Heredia de la Cruz, Ivan/0000-0002-8133-6467; Cassese, Antonio/0000-0003-3010-4516; Schulte, Jan-Frederik/0000-0003-4421-680X; Klein, Daniel/0000-0001-9143-5162; Moran, Dermot/0000-0002-1941-9333; Navarro-Tobar, Alvaro/0000-0003-3606-1780; Staiano, Amedeo/0000-0003-1803-624X; Hill, Christopher/0000-0003-0059-0779; Androsov, Konstantin/0000-0003-2694-6542; Vartak, Adish/0000-0003-1507-1365; Viliani, Lorenzo/0000-0002-1909-6343; Backhaus, Malte/0000-0002-5888-2304; Joshi, Yagya/0000-0002-0651-1878; Dragicevic, Marko/0000-0003-1967-6783; Abbiendi, Giovanni/0000-0003-4499-7562; Buchanan, James/0000-0001-8207-5556; Beaudette, Florian/0000-0002-1194-8556; Tosi, Nicolo/0000-0002-0474-0247; Gershtein, Yuri/0000-0002-4871-5449; Grohsjean, Alexander/0000-0003-0748-8494; Ruiz, Jose/0000-0002-3306-0363; Fiorendi, Sara/0000-0003-3273-9419; Pieri, Marco/0000-0003-3303-6301; Belyaev, Alexander/0000-0002-1733-4408; Ramirez Garcia, Mateo/0000-0002-4564-3822; Sznajder, Andre/0000-0001-6998-1108; YOON, INSEOK/0000-0002-3491-8026; Gutsche, Oliver/0000-0002-8015-9622; Harb, Ali/0000-0001-5750-3889; Belloni, Alberto/0000-0002-1727-656X; Wardle, Nicholas/0000-0003-1344-3356; Galli Mercadante, Pedro/0000-0001-8333-4302; Ghosh, Saranya/0000-0001-6717-0803; Costa, Salvatore/0000-0001-9919-0569; Ecklund, Karl/0000-0002-6976-4637; Mousa, Jehad/0000-0002-2978-2718; Snoeys, Walter/0000-0003-3541-9066; Massironi, Andrea/0000-0002-0782-0883; Diaz, Daniel/0000-0001-6834-1176; Heath, Helen/0000-0001-6576-9740; Salvatico, Riccardo/0000-0002-2751-0567; Arcidiacono, Roberta/0000-0001-5904-142X; Govoni, Pietro/0000-0002-0227-1301; Starling, Elizabeth/0000-0002-4399-7213; Ricci-Tam, Francesca/0000-0001-9750-7702; Bodek, Arie/0000-0003-0409-0341; Fiorina, Davide/0000-0002-7104-257X; Goldstein, Joel/0000-0003-1591-6014; Rappoccio, Salvatore/0000-0002-5449-2560; Carrillo Montoya, Camilo/0000-0002-6245-6535; Mora Herrera, Maria Clemencia/0000-0003-3915-3170; Heindl, Maximilian/0000-0002-2831-463X; Murillo Quijada, Javier Alberto/0000-0003-4933-2092; Bhowmik, Sandeep/0000-0003-1260-973X; Mrenna, Stephen/0000-0001-8731-160X; Delaere, Christophe/0000-0001-8707-6021; Dallavalle, Gaetano Marco/0000-0002-8614-0420; Doroba, Krzysztof/0000-0002-7818-2364; Vischia, Pietro/0000-0002-7088-8557; CUFFIANI, Marco/0000-0003-2510-5039; Monaco, Vincenzo/0000-0002-3617-2432; ALCARAZ MAESTRE, JUAN/0000-0003-0914-7474; David, Pieter/0000-0001-9260-9371; Bachiller, IreneBachiller/0000-0002-3721-4876; Tavolaro, Vittorio Raoul/0000-0003-2518-7521; Frankenthal, Andre/0000-0002-2583-5982; lee, jason/0000-0002-2153-1519; Ivanov, Andrew/0000-0002-9270-5643; Usai, Emanuele/0000-0001-9323-2107; Martinez Ruiz del Arbol, Pablo/0000-0002-7737-5121; Shchutska, Lesya/0000-0003-0700-5448; Tapper, Alexander/0000-0003-4543-864X; Haddad, Yacine/0000-0003-4916-7752; Forthomme, Laurent/0000-0002-3302-336X; Veckalns, Viesturs/0000-0003-3676-9711; Gerosa, Raffaele/0000-0001-8359-3734; Sharma, Varun/0000-0003-1287-1471; d'Enterria, David/0000-0002-5754-4303; Leonardo, Nuno/0000-0002-9746-4594; Waltenberger, Wolfgang/0000-0002-6215-7228; Giacomelli, Paolo/0000-0002-6368-7220; Fernandez Ramos, Juan Pablo/0000-0002-0122-313X; Dubinin, Mikhail/0000-0002-7766-7175; Li, Qiang/0000-0002-8290-0517; Lethuillier, Morgan/0000-0001-6185-2045; Reis, Thomas/0000-0003-3703-6624; Landsberg, Greg/0000-0002-4184-9380; Zuolo, Davide/0000-0003-3072-1020; Hernandez Calama, Jose Maria/0000-0001-6436-7547; Rossi, Biagio/0000-0002-0807-8772; Sosa Ricardo, Rafael Eduardo/0000-0002-2240-6699; Dominguez, Aaron/0000-0002-7420-5493; Fernandez Perez Tomei, Thiago Rafael/0000-0002-1809-5226; Pastrone, Nadia/0000-0001-7291-1979; Pantaleo, Felice/0000-0003-3266-4357; Lawhorn, Jay/0000-0002-8597-9259; Cepeda, Maria/0000-0002-6076-4083; Kreczko, Luke/0000-0003-2341-8330; Dharmaraatna, Welathantri/0000-0002-6366-837X; Mitra, Soureek/0000-0002-3060-2278; Malik, Sudhir/0000-0002-6356-2655; Novaes, Sergio/0000-0003-0471-8549; Shevchenko, Rostyslav/0000-0002-3236-4090; Gomez, Gervasio/0000-0002-1077-6553; Ptochos, Fotios/0000-0002-3432-3452; Verweij, Marta/0000-0002-1504-3420; Hall, Geoffrey/0000-0002-6299-8385; Lucchini, Marco Toliman/0000-0002-7497-7450; Ince Lezki, Merve/0000-0001-6907-0195; Zorbakir, Ibrahim Soner/0000-0002-5962-2221; Bhandari, Rohan/0000-0001-5888-955X; Collard, Caroline/0000-0002-5230-8387; Kayis Topaksu, Aysel/0000-0002-3169-4573; Rolandi, Luigi (Gigi)/0000-0002-0635-274X; Smith, Wesley/0000-0003-3195-0909; Ulrich, Ralf/0000-0002-2535-402X; Kiminsu, Ugur/0000-0001-6940-7800; Mundim, Luiz/0000-0001-9964-7805; Van Onsem, Gerrit/0000-0002-1664-2337; Watson, Ian/0000-0003-2141-3413; Spagnolo, Paolo/0000-0001-7962-5203; Ruiz Jimeno, Alberto/0000-0002-3639-0368; Pfeiffer, Andreas/0000-0001-5328-448X; Garcia, Francisco/0000-0002-4023-7964; Rizzi, Andrea/0000-0002-4543-2718; Kasemann, Matthias/0000-0002-0429-2448; Kole, Gouranga/0000-0002-3285-1497; FORD, WILLIAM/0000-0001-8703-6943; ASILAR, Ece/0000-0001-5680-599X; Tinoco Mendes, Andre David/0000-0001-5854-7699; Konecki, Marcin/0000-0001-9482-4841; Canelli, Florencia/0000-0001-6361-2117; Saka, Halil/0000-0001-7616-2573; Goy Lopez, Silvia/0000-0001-6508-5090; Blumenfeld, Barry/0000-0003-1150-1735; Popov, Andrey/0000-0002-1207-0984; CHANG, PAO-TI/0000-0003-4064-388X; Kothekar, Kunal/0000-0001-5102-4326; Giammanco, Andrea/0000-0001-9640-8294; Belforte, Stefano/0000-0001-8443-4460; Schroder, Matthias/0000-0001-8058-9828; Benitez, Jose Feliciano/0000-0002-2633-6712; Lange, Johannes/0000-0001-7513-6330; Schonenberger, Myriam/0000-0002-6508-5776; Faccioli, Pietro/0000-0003-1849-6692; Chauhan, Shubhanshu/0000-0002-6544-5794; Shah, Aashaq/0000-0002-6157-2016; Alves, Gilvan/0000-0002-8369-1446; Vami, Tamas Almos/0000-0002-0959-9211; Myronenko, Volodymyr/0000-0002-3984-4732; Paulini, Manfred/0000-0002-6714-5787; Felcini, Marta/0000-0002-2051-9331; Garutti, Erika/0000-0003-0634-5539; Palladino, Vito/0000-0002-9786-9620; Mitselmakher, Guenakh/0000-0001-5745-3658; Trevisani, Nicolo/0000-0002-5223-9342; Sciacca, Crisostomo/0000-0002-8412-4072; Litov, Leandar/0000-0002-8511-6883; Consuegra Rodriguez, Sandra/0000-0002-1383-1837; Hurtado Anampa, Kenyi/0000-0002-9779-3566; Golf, Frank/0000-0003-3567-9351; Zenz, Seth/0000-0002-9720-1794; Lo Meo, Sergio/0000-0003-3249-9208; Moon, Chang-Seong/0000-0001-8229-7829; Kim, Tae Jeong/0000-0001-8336-2434; Krintiras, Georgios Konstantinos/0000-0002-0380-7577; Taylor, Lucas/0000-0002-6584-2538; Shopova, Mariana/0000-0001-6664-2493; Botta, Cristina/0000-0002-8072-795X; Conway, John/0000-0003-2719-5779; Tonelli, Guido Emilio/0000-0003-2606-9156; Zanetti, Marco/0000-0003-4281-4582; Sanchez-Hernandez, Alberto/0000-0001-9548-0358; Cavallari, Francesca/0000-0002-1061-3877; Padula, Sandra S./0000-0003-3071-0559; Fernandez Menendez, Javier/0000-0002-5213-3708; Robert, Schoefbeck/0000-0002-2332-8784; Csanad, Mate/0000-0002-3154-6925; Caputo, Claudio/0000-0001-7522-4808; Kratochwil, Nicolaus/0000-0001-5297-1878; Kyberd, Paul/0000-0002-7353-7090; Bernardes, Cesar Augusto/0000-0001-5790-9563; Fernandez Bedoya, Cristina/0000-0001-8057-9152; Zghiche, Amina/0000-0002-1178-1450; Ebrahimi, Aliakbar/0000-0003-4472-867X; Brigljevic, Vuko/0000-0001-5847-0062; Gonzalez Caballero, Isidro/0000-0002-8087-3199; Klanner, Robert/0000-0002-7004-9227; Puerta Pelayo, Jesus/0000-0001-7390-1457; Mnich, Joachim/0000-0001-7242-8426; Moraes, Arthur/0000-0002-5157-5686; Dogra, Sunil/0000-0002-0812-0758; Martelli, Arabella/0000-0003-3530-2255; Dewanjee, Ram Krishna/0000-0001-6645-6244; Hamel de Monchenault, Gautier/0000-0002-3872-3592; Jafari, Abideh/0000-0001-7327-1870; Sharma, Ram Krishna/0000-0003-1181-1426; Rabbertz, Klaus/0000-0001-7040-9846; Haller, Johannes/0000-0001-9347-7657; Benato, Lisa/0000-0001-5135-7489; Krikler, Benjamin/0000-0001-9712-0030; Petrucciani, Giovanni/0000-0003-0889-4726; Chapon, Emilien/0000-0001-6968-9828; Azzi, Patrizia/0000-0002-3129-828X; Piperov, Stefan/0000-0002-9266-7819; Wu, Zhenbin/0000-0003-2165-9501; Tholen, Heiner/0000-0002-2299-2421; Zhang, Zhicai/0000-0002-1630-0986; Bartok, Marton/0000-0002-4440-2701; Akgun, Bora/0000-0001-8888-3562; Vilela Pereira, Antonio/0000-0003-3177-4626; Grandi, Claudio/0000-0001-5998-3070; Sanchez Navas, Sergio/0000-0001-6129-9059; Nguyen, Thong Q./0000-0003-3954-5131; Cristella, Leonardo/0000-0002-4279-1221; Bloom, Kenneth/0000-0002-4272-8900; Keaveney, James/0000-0003-0766-5307; Wuyckens, Sophie/0000-0002-5092-7213; Tosi, Silvano/0000-0002-7275-9193; Redondo, Ignacio/0000-0003-3737-4121; Raidal, Martti/0000-0001-7040-9491; Sagir, Sinan/0000-0002-2614-5860; Bravo, Cameron/0000-0003-1102-8247; Zucchetta, Alberto/0000-0003-0380-1172; Bansal, Sunil/0000-0003-1992-0336; Heikkila, Jaana/0000-0002-0538-1469; Sculac, Toni/0000-0002-9578-4105; Manca, Elisabetta/0000-0001-8946-655X; Grunewald, Martin/0000-0002-5754-0388; Everaerts, Pieter/0000-0003-3848-324X; Lange, Clemens/0000-0002-3632-3157; Levchuk, Leonid/0000-0001-5889-7410; Marzocchi, Badder/0000-0001-6687-6214; Wilson, Graham/0000-0003-0917-4763; Schwandt, Joern/0000-0002-0052-597X; Alverson, George/0000-0001-6651-1178; Cadamuro, Luca/0000-0001-8789-610X; Naimuddin, Md/0000-0003-4542-386XA search is presented for long-lived charged particles that decay within the volume of the silicon tracker of the CMS experiment. Such particles can produce events with an isolated track that is missing hits in the outermost layers of the silicon tracker, and is also associated with little energy deposited in the calorimeters and no hits in the muon detectors. The search for events with this "disappearing track" signature is performed in a sample of proton-proton collisions recorded by the CMS experiment at the LHC with a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 101 fb(-1) recorded in 2017 and 2018. The observation of 48 events is consistent with the estimated background of 47.8(-2.3)(+2.7) (stat) +/- 8.1 (syst) events. Upper limits are set on chargino production in the context of an anomaly-mediated supersymmetry breaking model for purely wino and higgsino neutralino scenarios. At 95% confidence level, the first constraint is placed on chargino masses in the higgsino case, excluding below 750 (175)GeV for a lifetime of 3 (0.05)ns. In the wino case, the results of this search are combined with a previous CMS search to produce a result representing the complete LHC data set recorded in 2015-2018, the most stringent constraints to date. At 95% confidence level, chargino masses in the wino case are excluded below 884 (474)GeV for a lifetime of 3 (0.2)ns. (C) 2020 The Author(s). Published by Elsevier B.V.BMBWF (Austria); FWF (Austria)Austrian Science Fund (FWF); FNRS (Belgium)Fonds de la Recherche Scientifique - FNRS; FWO (Belgium)FWO; CNPq (Brazil)National Council for Scientific and Technological Development (CNPq); CAPES (Brazil)CAPES; FAPERJ (Brazil)Carlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro (FAPERJ); FAPERGS (Brazil)Foundation for Research Support of the State of Rio Grande do Sul (FAPERGS); FAPESP (Brazil)Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP); MES (Bulgaria); CERN; CAS (China)Chinese Academy of Sciences; MOST (China)Ministry of Science and Technology, China; NSFC (China)National Natural Science Foundation of China (NSFC); COLCIENCIAS (Colombia)Departamento Administrativo de Ciencia, Tecnologia e Innovacion Colciencias; MSES (Croatia); CSF (Croatia); RPF (Cyprus); SENESCYT (Ecuador); MoER (Estonia); ERC IUT (Estonia)Estonian Research Council; PUT (Estonia); ERDF (Estonia)European Union (EU); Academy of Finland (Finland)Academy of Finland; MEC (Finland); HIP (Finland); CEA (France)French Atomic Energy Commission; CNRS/IN2P3 (France)Centre National de la Recherche Scientifique (CNRS); BMBF (Germany)Federal Ministry of Education & Research (BMBF); DFG (Germany)German Research Foundation (DFG); HGF (Germany); GSRT (Greece)Greek Ministry of Development-GSRT; NKFIA (Hungary); DAE (India)Department of Atomic Energy (DAE); DST (India)Department of Science & Technology (India); IPM (Iran); SFI (Ireland)Science Foundation Ireland; INFN (Italy)Istituto Nazionale di Fisica Nucleare (INFN); MSIP (Republic of Korea); NRF (Republic of Korea); MES (Latvia); LAS (Lithuania); MOE (Malaysia); UM (Malaysia); BUAP (Mexico); CINVESTAV (Mexico); CONACYT (Mexico)Consejo Nacional de Ciencia y Tecnologia (CONACyT); LNS (Mexico); SEP (Mexico); UASLP-FAI (Mexico); MOS (Montenegro); MBIE (New Zealand); PAEC (Pakistan); MSHE (Poland); NSC (Poland); FCT (Portugal)Portuguese Foundation for Science and Technology; JINR (Dubna); MON (Russia); RosAtom (Russia); RAS (Russia)Russian Academy of Sciences; RFBR (Russia)Russian Foundation for Basic Research (RFBR); NRC KI (Russia); MESTD (Serbia); SEIDI (Spain); CPAN (Spain); PCTI (Spain); FEDER (Spain)European Union (EU); MoSTR(Sri Lanka); Swiss Funding Agencies (Switzerland); MST (Taipei); ThEPCenter (Thailand); IPST (Thailand); STAR (Thailand); NSTDA (Thailand); TUBITAK (Turkey)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK); TAEK (Turkey)Ministry of Energy & Natural Resources - Turkey; NASU (Ukraine); STFC (United Kingdom)Science & Technology Facilities Council (STFC); DOE (USA)United States Department of Energy (DOE); NSF (USA)National Science Foundation (NSF); Marie-Curie program (European Union)European Union (EU); European Research Council (European Union)European Union (EU)European Research Council (ERC) [675440, 752730, 765710]; Horizon 2020 Grant (European Union)European Union (EU) [675440, 752730, 765710]; Leventis Foundation; Alfred P. Sloan FoundationAlfred P. Sloan Foundation; Alexander von Humboldt FoundationAlexander von Humboldt Foundation; Belgian Federal Science Policy OfficeBelgian Federal Science Policy Office; Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium)Fonds de la Recherche Scientifique - FNRS; Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium)Institute for the Promotion of Innovation by Science and Technology in Flanders (IWT); F.R.S.-FNRS (Belgium) under the "Excellence of Science -EOS" - be.h projectFonds de la Recherche Scientifique - FNRS [30820817]; FWO (Belgium) under the "Excellence of Science -EOS" - be.h projectFWO [30820817]; Beijing Municipal Science & Technology CommissionBeijing Municipal Science & Technology Commission [Z191100007219010]; Ministry of Education, Youth and Sports(MEYS) of the Czech RepublicMinistry of Education, Youth & Sports - Czech Republic; Deutsche Forschungsgemeinschaft (DFG) under Germany's Excellence StrategyGerman Research Foundation (DFG) [EXC 2121, 390833306]; Lendulet ("Momentum") Program of the Hungarian Academy of Sciences; Janos Bolyai Research Scholarship of the Hungarian Academy of SciencesHungarian Academy of Sciences; New National Excellence Program UNKP; NKFIA (Hungary) [123842, 123959, 124845, 124850, 125105, 128713, 128786, 129058]; Council of Science and Industrial Research, IndiaCouncil of Scientific & Industrial Research (CSIR) - India; HOMING PLUS program of the Foundation for Polish Science; European Union, Regional Development FundEuropean Union (EU); Mobility Plus program of the Ministry of Science and Higher Education; National Science Centre(Poland)National Science Center, PolandNational Science Centre, Poland [Harmonia 2014/14/M/ST2/00428, Opus 2014/13/B/ST2/02543, 2014/15/B/ST2/03998, 2015/19/B/ST2/02861, Sonata-bis 2012/07/E/ST2/01406]; National Priorities Research Program by Qatar National Research Fund; Ministry of Science and Education (Russia) [14.W03.31.0026]; Tomsk Polytechnic University Competitiveness Enhancement Program (Russia); "Nauka" Project (Russia) [FSWW-2020-0008]; Programa Estatal de Fomento de la Investigacion Cientifica y Tecnica de Excelencia Maria de Maeztu [MDM-2015-0509]; Programa Severo Ochoa del Principado de Asturias; Thalis program - EU-ESF; Aristeia program - EU-ESF; Greek NSRFGreek Ministry of Development-GSRT; Rachadapisek Sompot Fund for Postdoctoral Fellowship, Chulalongkorn University (Thailand); Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand); Kavli Foundation; Nvidia Corporation; SuperMicro Corporation; Welch FoundationThe Welch Foundation [C-1845]; Weston Havens Foundation (USA)We congratulate our colleagues in the CERN accelerator departments for the excellent performance of the LHC and thank the technical and administrative staffs at CERN and at other CMS institutes for their contributions to the success of the CMS effort. In addition, we gratefully acknowledge the computing centers and personnel of the Worldwide LHC Computing Grid for delivering so effectively the computing infrastructure essential to our analyses. Finally, we acknowledge the enduring support for the construction and operation of the LHC and the CMS detector provided by the following funding agencies: BMBWF and FWF (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ, FAPERGS, and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MOST, and NSFC (China); COLCIENCIAS (Colombia); MSES and CSF (Croatia); RPF (Cyprus); SENESCYT (Ecuador); MoER, ERC IUT, PUT and ERDF (Estonia); Academy of Finland, MEC, and HIP (Finland); CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece); NKFIA (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); MSIP and NRF (Republic of Korea); MES (Latvia); LAS (Lithuania); MOE and UM (Malaysia); BUAP, CINVESTAV, CONACYT, LNS, SEP, and UASLP-FAI (Mexico); MOS (Montenegro); MBIE (New Zealand); PAEC (Pakistan); MSHE and NSC (Poland); FCT (Portugal); JINR (Dubna); MON, RosAtom, RAS, RFBR, and NRC KI (Russia); MESTD (Serbia); SEIDI, CPAN, PCTI, and FEDER (Spain); MoSTR(Sri Lanka); Swiss Funding Agencies (Switzerland); MST (Taipei); ThEPCenter, IPST, STAR, and NSTDA (Thailand); TUBITAK and TAEK (Turkey); NASU (Ukraine); STFC (United Kingdom); DOE and NSF (USA).; Individuals have received support from the Marie-Curie program and the European Research Council and Horizon 2020 Grant, contract Nos. 675440, 752730, and 765710 (European Union); the Leventis Foundation; the Alfred P. Sloan Foundation; the Alexander von Humboldt Foundation; the Belgian Federal Science Policy Office; the Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium); the Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium); the F.R.S.-FNRS and FWO (Belgium) under the "Excellence of Science -EOS" - be.h project n. 30820817; the Beijing Municipal Science & Technology Commission, No. Z191100007219010; The Ministry of Education, Youth and Sports(MEYS) of the Czech Republic; the Deutsche Forschungsgemeinschaft (DFG) under Germany's Excellence Strategy - EXC 2121 "Quantum Universe" - 390833306; the Lendulet ("Momentum") Program and the Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences, the New National Excellence Program UNKP, the NKFIA research grants 123842, 123959, 124845, 124850, 125105, 128713, 128786, and 129058 (Hungary); the Council of Science and Industrial Research, India; the HOMING PLUS program of the Foundation for Polish Sc
Su ayrıştırma uygulamaları için mürekkep püskürtme baskılı çoklu metal oksit fotoelektrotların deneysel analizi
No full textThesis (Master)--Izmir Institute of Technology, Materials Science and Engineering, Izmir, 2020Includes bibliographical references (leaves: 58-63):Text in English; Abstract: Turkish and EnglishRecently, scientific research studies focus on renewable energy solutions as well as energy efficiency in managing the upcoming climate crisis which manifests itself in the form of global warming. However, the chaotic nature of renewable energy sources caused energy storage technologies to gain importance. In addition to battery technologies consisting of lithium and post-lithium ion, zinc-air, nickel-zinc and lead-acid; artificial photosynthesis products such as hydrogen and methanol also show superiority in transportation. Especially hydrogen fuel is in the leading position with gravimetric energy density of approximately 140 MJ/kg. In this study, the experimental procedure is conducted and analyzed to produce cost-effective multi-metal oxide catalysts at high speed and efficiency with a combinatorial approach using inkjet printing technology to obtain hydrogen by splitting water. Considering the abundancies in nature, especially nickel, cobalt, iron, manganese, copper and chromium salts were preferred to obtain oxide derivatives. Inkjet printing experiments were conducted with the printer provided by Sağlık İzleme Sistemleri A.Ş.. The precision of the printed layers was examined and compared with the literature values. In cases involving differences from the literature value, possible causes are emphasized and solutions are suggested. Problems in transition from single metal oxide printed layers to more complicated multi-metal oxide prints have been examined and solutions have been proposed. As a result, this experimental study is aimed to provide foresight for large-scale (photo)electrocatalyst production with the utilization of inkjet printing.Günümüzde küresel ısınma şeklinde kendini gösteren, yaklaşmakta olan iklim krizinin yönetilmesinde enerji verimliliğinin yanısıra yenilenebilir enerji çözümlerine odaklanılmaktadır. Bununla birlikte yenilenebilir enerji kaynaklarının kaotik yapısı enerji depolamanın daha fazla önem kazanmasına yol açmıştır. Lityum ve post-lityum iyon, çinko-hava, nikel-çinko ve kurşun-asitten oluşan pil teknolojilerine ek olarak gravimetrik enerji yoğunluğu bu teknolojilerden çok daha fazla olan, hidrojen ve metanol gibi yapay fotosentez ürünleri buna ek olarak taşınabilirlik konusunda da üstünlük göstermektedir. Özellikle hidrojen yakıtı yaklaşık olarak 140 MJ/kg'lık gravimetrik enerji yoğunluğuyla lider konumdadır. Bu çalışmada suyun ayrıştırılmasıyla hidrojen eldesi için mürekkep püskürtme baskı teknolojisi kullanılarak kombinasyonel yaklaşımla düşük maliyetli çoklu metal oksit katalizörlerinin yüksek hız ve verimde üretilmesi için deneysel prosedür incelenmiş ve analiz edilmiştir. Doğada bulunma sıklığı göz önüne alınarak oksit türevlerinin eldesi için özellikle nikel, kobalt, demir, mangan, bakır ve krom tuzları tercih edilmiştir. Mürekkep püskürtme baskı denemelerinin tümü Sağlık İzleme Sistemleri A.Ş. tarafından sağlanan yazıcıyla yapılmıştır. Baskıların hassasiyetleri incelenmiş olup literatür değerleriyle karşılaştırma yapılmıştır. Literatür değerinden farklılıklar içeren durumlarda olası nedenler üzerinde durulmuş ve çözüm yolları önerilmiştir. Tekli metal oksit baskılardan daha komplike olan çoklu metal oksit baskılara geçişte yaşanan problemler incelenmiş ve çözüm önerileri getirilmiştir. Sonuç olarak yapılan deneysel çalışmanın mürekkep püskürtme baskı kullanılarak büyük ölçekli (foto)elektrokatalizör üretimine yönelik öngörü sağlaması hedeflenmiştir