The University of Kansas: Journals@KU
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Evaluating the Relationship Between Redlining and Food Allergy for The University of Kansas Medical Center Pediatric Patients
Evaluating the Evidence for Genetics/Genomics in Chronic Pain: An Integrative Literature Review
Fenestrated Endovascular Repair of a Thoracoabdominal Aortic Aneurysm and Splenorenal Bypass in a Patient with Prior Dissection History
Continuity of care? Hospitalists? Who calls the family?: Corporate control makes health care worse.
POEMS Syndrome: A Case Highlighting the Challenges in Diagnosis
POEMS syndrome is a multisystem disorder characterized by polyneuropathy, organomegaly, endocrinopathy, and skin changes in the context of a monoclonal plasma cell disorder. While these features may appear in the syndrome, they do not always occur simultaneously and can present with multiple other symptoms. A thorough laboratory and radiological workup is recommended to assess for multisystem involvement, and a bone marrow or skeletal lesion biopsy may be necessary to confirm an underlying plasma cell disorder. Given the wide range of possible presentations, diagnosing POEMS can be challenging and may be confused with CIDP or smoldering myeloma. However, maintaining a high clinical suspicion this syndrome, even when not all features are present, is crucial for a timely diagnosis and optimal treatment, particularly for neurological recovery. We present the case of a 57-year-old male with progressive sensorimotor weakness who was initially diagnosed with CIDP but ultimately found to have POEMS syndrome, based on elevated VEGF levels, IgG lambda monoclonal gammopathy, sclerotic bone lesions, skin changes, endocrinopathy, and a biopsy-proven plasmacytoma
From liver enzymes to lysosomes: a serendipitous diagnosis of late-onset Pompe disease: Diagnosis of late-onset Pompe disease
One’s trash is another’s retreat: Reptiles and amphibians recorded beneath dumped materials in western Sydney, Australia
Mass dumping of unwanted materials is a serious issue in many regions, though ironically these materials inadvertently provide artificial refugia for herpetofauna. Over a period of 17 years, we observed 26 species of squamates and 13 species of anurans in remnant bushland areas in western Sydney. Of these, 20 species of squamates from five families (Agamidae, Diplodactylidae, Elapidae, Scincidae and Typhlopidae) and nine anuran species from three families (Hylidae, Limnodynastidae and Myobatrachidae) were found by searching beneath dumped materials. This constitutes a large proportion of observed species (74%) using dumped materials as refugia, which reinforces how much these non-natural materials can be advantageously leveraged for detecting herpetofauna. In particular, our detections of three snake species, the Red-naped Snake (Furina diadema), Golden-crowned Snake (Cacophis squamulosus) and Blackish Blindsnake (Anilios nigrescens), were exclusively from searching under dumped materials. Two other species, the Yellow-faced Whipsnake (Demansia psammophis) and Smooth Toadlet (Uperoleia laevigata), were predominantly detected by lifting dumped materials. Thus, the availability of such materials to search under appeared to facilitate substantial amounts of detections of these species