The University of Kansas: Journals@KU
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Investigating the Effects of Doxorubicin on Mesenchymal Versus Basal Triple Negative Breast Cancer Survival in 3D Culture
Lipid Peroxidation as a Biomarker for Heavy Metal Stress in Plants
Heavy metal contamination in soil poses a significant threat to plant health, agriculture, and ecological stability. This study investigates the potential of lipid peroxidation, specifically malondialdehyde (MDA) accumulation, as a biomarker for oxidative stress in plants exposed to heavy metals. Plants were subjected to varying concentrations of Copper Sulfate, and physiological parameters such as root length were recorded to assess growth inhibition. To quantify lipid peroxidation, a thiobarbituric acid reactive substances (TBARS) assay was performed, with a standard curve generated using 1,1,3,3-tetramethoxypropane (TMP) as an MDA equivalent. Results revealed a dose-dependent increase in MDA levels correlating with reduced root growth, indicating enhanced oxidative damage under metal stress. These findings support the use of lipid peroxidation as a reliable indicator of heavy metal toxicity and lay the groundwork for its application in phytoremediation studies and environmental monitoring
A Humanizing Rewrite for CAR T Cells in Autoimmune Disease: A StepToward Repeatable, Durable Therapy
Spinocerebellar Ataxia and Necrotizing Myositis: Two coexisting pathologies in a case of progressive neurologic dysfunction
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Ecological Relationships and Succession in an Urban South Florida Herpetofaunal Community during 2006–2021: A Case Study
Visual encounter surveys comprised a case study of urban ecology conducted along a 3.22 km sidewalk loop in a residential development in southern Florida during March 2006–June 2021. The Nautica, a gated residential development, was completed in the early 2000s and initial investigations of the herpetofauna began shortly thereafter. Species accumulation was rapid, with 10 native and 13 exotic species comprising the herpetofaunal community. The construction of Nautica occurred on a highly modified habitat in which many native species were marginalized and several exotic species, also already there, could take advantage of the subsequent structural and hydrological changes culminating in the creation of this subdivision. Colonization patterns, persistence, and abundance varied widely among species. Measurement of abiotic factors associated with standardized focal surveys provided information to predict the likelihoods of activity by members of the herpetofaunal community and the detection of interspecific interactions that affect their activity patterns. Exotic-species-dominated artificial systems are commonplace in southern Florida and bring with them a conservation need for awareness to understand the ways in which residential species interact with and impact their environment and other species, including avian predators and feral cats. To that end, in the nearly two decades since the construction of Nautica, the native terrestrial herpetofauna has remained depauperate, while exotic counterparts underwent accelerated colonization patterns, with one species possibly contributing to the persistence of a native lizard