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A Prospective Cohort study to Compare the Perinatal and Neonatal Outcomes in Nulliparous Women with Increased Versus Normal Body Mass Index
Get PDFOBJECTIVE:
To compare the maternal and perinatal outcomes in nulliparous pregnant women with increased versus normal body mass index in a tertiary care hospital.
METHODS:
This was a prospective cohort study done at a tertiary care centre in South India that compared maternal characteristics, antenatal complications, intrapartum characteristics, postnatal complications and neonatal complications between women with increased BMI versus those with normal BMI. Asia-Pacific cut-offs were used to define obesity.
RESULTS:
A total of 440 women were recruited of which 229 were in group I and 211 in group II. GDM was significantly increased in the obese group as compared to the normal group BMI (37.1% versus 23.7% p-value 0.02) The other antenatal complications like GHTN, miscarriages and stillbirths were comparable across both the groups.
Significantly more number of women required induction of labour in the obese group (63.3% versus 42.7%, p value 0.00) and cumulative dose of oxytocin required for augmentation of labour was also more in the obese group (510 ml versus 397 ml, p-value 0.001).
Obese women had increased rates of operative vaginal delivery (32.8% versus 20.4%, p-value 0.013). Cesarean delivery rates were similar across both the groups. The postnatal complications like endometritis, episiotomy/LSCS wound infection, need for IV antibiotics were similar.
Mean birthweight was significantly increased in group I than in group II (2.97 kg versus 2.71 kg, p-value <0.001) whereas the other characteristics like macrosomia, APGAR score <7 at 5 minutes, NICU admission and neonatal sepsis were similar across both groups.
CONCLUSION: Increased maternal BMI is associated with adverse perinatal and neonatal outcomes
Impact of early Vs delayed fortification of human milk on growth of preterm low birth weight neonates: An open label, parallel, randomized control, superiority trial
No full textIncidence of Atrial Infarction in Acute ST Elevation Myocardial Infarction and Its Complications
No full textBACKGROUND:
Atrial infarction, which frequently occurs together with ventricular infarction, is underappreciated and understudied. The aim of the study is to identify atrial infarction in acute ST elevation myocardial infarction using ECG based on Liu et all criteria and to correlate the associated arrhythmias and other complications.
MATERIALS AND METHODS:
This is a cross sectional analytical study conducted in a tertiary care institution in South India. The sample size was calculated to be 137 patients with STEMI using OpenEpi v3.0 Study participants who satisfied the eligibility criteria were recruited consecutively. After obtaining informed consent, information regarding sociodemographic characteristics, relevant history, blood pressure, ECG, ECHO, Angiogram parameters, complications and outcomes were recorded. Data entry was done using Microsoft Excel 2016. Data analysis was done using SPSS Version 20.0. (77) Statistical significance was considered when P value was less than 0.05.
RESULTS:
Out of 137 individuals with STEMI who were recruited for the current study, 53 (38.7%) study participants had atrial infarction. More than 60% of the study participants belonged to 51 – 70 years age group, while around 7.3 % belonged to age group less
than 40 years. Nearly three out of every four study participants in the current study were males. nearly one third of the study participants had both diabetes and systemic hypertension as comorbidities. More than one fifth of the study participants had either hypokinesia of inferior, infero-septal or inferior, infero-septal and posterior wall. Anterior septal alone and anterior septal along with antero-lateral wall contributed for 6% of all study participants. The angiogram findings in the current showed that RCA, RCA dominant, mild RCA and distal RCA contributed to 21.8% of the total number of study participants who underwent angiogram.
CONCLUSION:
This study concludes that about one in every three cases of myocardial infarction might have atrial infarction. Regional wall abnormality and artery involved were found to be significant on comparison based on atrial infarction as well as complications. Further studies need to be conducted to explore on the results obtained from the current study
A Study of Diastolic Dysfunction in Asymptomatic Type 2 Diabetes Mellitus Patients using 2D Echocardiogram and Tissue Doppler Imaging in Coimbatore Medical College Hospital
No full textA Prospective study on the Diagnostic Value of Serum Bilurubin in Predicting Appendicitis and Its Severity
No full textA Prospective study on Evaluating the Efficacy of Mastectomy Flap Fixation by Quilting Technique in Reducing Postmastectomy Seroma
No full text
Capecitabine Based Chemoradiation in Cisplatin Ineligible Patients of Locally Advanced Carcinoma of Uterine Cervix: Prospective Observational study
No full text
