E-Journal Faculty of Medicine Universitas Padjadjaran / E-Jurnal Fakultas Kedokteran Universitas Padjadjaran
Not a member yet
1208 research outputs found
Sort by
Korelasi Modified Nutric Score Dengan Mortalitas 28 Hari Pasien Sepsis Di Unit Perawatan Intensif Rsup Dr. Mohammad Hoesin Palembang
Get PDFMalnutrisi merupakan masalah penting pada pasien sepsis karena memperburuk outcome akibat penyembuhan luka terganggu, menurunkan fungsi imun, risiko infeksi tinggi, kelemahan otot sehingga weaning ventilator mekanik lebih sulit, meningkatkan lama tinggal dan biaya tinggi di unit perawatan intensif serta peningkatan mortalitas. Skrining risiko nutrisi saat pasien masuk unit perawatan intensif dengan modified NUTRIC score dapat mengidentifikasi kelompok risiko nutrisi tinggi atau risiko rendah. Penelitian kohort retrospektif untuk mengetahui korelasi antara modified NUTRIC score dengan mortalitas pada pasien sepsis yang dirawat dari Januari‒Desember 2018 di RSUP Dr. Mohammad Hoesin Palembang. Jumlah sampel 100 orang, dibagi 2 kelompok berdasarkan mortalitas, kemudian dilakukan pengukuran modified NUTRIC score yang terdiri dari usia, skor APACHE II, skor SOFA, lama rawat sebelum masuk perawatan intensif, dan jumlah komorbid. Modified NUTRIC score memiliki nilai 0‒9. Hasil analisis ROC curve modified NUTRIC score dengan mortalitas didapatkan sensitiftas sebesar 96%, spesifisitas 71%, nilai area under the curve (AUC) 0,916 dengan nilai cut off >4. Terdapat korelasi antara modified NUTRIC score dengan mortalitas dalam 28 hari pasien sepsis dengan koefisien korelasi (r)=0,716 dan nilai p=0,0001. Correlation of Modified Nutric Score with 28-Day Mortality in Sepsis Patients at Intensive Care Unit of Dr. Mohammad Hoesin General Hospital PalembangMalnutrition is an essential problem to septic patients because it worsens the outcome due to impaired wound healing, decreases immune function, high risk of infection, and muscle weakness so that mechanical ventilator weaning is more complicated. Also, it increases the patient length of stay and costs in the intensive care unit and increases mortality. Nutrition risk screening on patients’ admission to the intensive care unit with modified NUTRIC score can identify groups of high nutritional risk or low risk. The retrospective cohort study aimed to determine the correlation between modified NUTRIC score and mortality in sepsis patients treated from January-December 2018 at dr. Mohammad Hoesin General Hospital Palembang. The total sample of 100 people was divided into 2 groups based on mortality then measured with modified NUTRIC score consisting of age, APACHE II score, SOFA score, length of stay before admission to the intensive care, and the number of comorbid based on data from medical records. Modified NUTRIC score has a value of 0‒9. The ROC curve modified NUTRIC score with mortality was 96% sensitivity, 71% specificity, area under curve (AUC) value 0.916 with a cut-off value >4. There is a correlation between the modified NUTRIC score and mortality in 28 days in sepsis patients in the Intensive Care Unit of Dr. Mohammad Hoesin General Hospital Palembang with a correlation coefficient (r) = 0,716 and p value 4. Dengan uji korelasi Eta, didapatkan korelasi antara Modified NUTRIC Score dengan mortalitas pasien sepsis dengan koefisien korelasi (r)=0,716 dan nilai p= 0,0001.Ada korelasi antara Modified NUTRIC Score terhadap mortalitas dalam 28 hari pada pasien sepsis di Unit Perawatan Intensif RSUP dr. Mohammad Hoesin Palemban
Effect of Iron Supplementation in Anti-Tuberculosis Drug Treatment on Interferon-γ Level in Tuberculosis Spondylitis Patients
Get PDFTuberculosis (TB) is still one of the major health problems in the community. Micronutrients, including iron, are crucial in the body's defense mechanism. Iron modulates the activation of IFN-γ, which in turn will activate the macrophages. This study explores the effect of iron supplementation given with anti-tuberculosis drug therapy on the IFN-γ level in tuberculosis spondylitis patients. This was a single-blind randomized control trial study at Dr. Hasan Sadikin General Hospital Bandung, from December 2018 to March 2019, using the consecutive sampling approach. Thirty-four respondents with category 1 TB spondylitis and an sTfR level of> 21.7 pg /µL were recruited and randomized into control and experimental groups. The control group (n=17) was treated with 2 RHZE for 2 months while the experimental group (n=17) received 2 RHZE and iron tablet for 2 months. An increase in the IFN-γ level of the experimental group was observed from an average of 21.7 pg/ml before therapy to an average of 72.39 pg/mL after therapy. Meanwhile, the IFN-γ level in the control group increases from an average of 22.5 pg/mL to an average of 35.35 pg/mL. This difference was statistically significant based on the analysis using the independent t-test (p-value 21,7 pg/µL. Kelompok kontrol 17 responden diterapi 2 RHZE. Kelompok eksperimen 17 responden diterapi 2 RHZE dengan tablet besi selama 2 bulan. Pada penelitian ini didapatkan peningkatan kadar IFN-γ rata-rata kelompok eksperimen (pemberian obat anti tuberkulosis dengan penambahan zat besi) dari 21,7 pg/mL sebelum dilakukan pemberian terapi menjadi rata-rata 72,39 pg/mL setelah dilakukan pemberian terapi diuji dengan uji t sampel independen (nilai p<0,05), secara statistik berbeda signifikan dengan kelompok kontrol (pemberian obat anti tuberkulosis), yaitu dari 22,5 pg/mL sebelum dilakukan pemberian terapi menjadi rata-rata 35,35 pg/mL setelah dilakukan pemberian terapi. Simpulan, pemberian obat anti tuberkulosis dengan penambahan zat besi dapat meningkatkan respon imun tubuh, yang ditandai dengan meningkatnya kadar IFN-γ
Hubungan Persentase Sel Leukosit Polimorfonuklear dalam Cairan Serebrospinal dan Luaran Pasien Meningitis Tuberkulosis di RSUP Dr. Hasan Sadikin Bandung
No full textTuberculous (TB) meningitis is the most severe type of extrapulmonary TB with high morbidity and mortality rates. Many factors affect patient outcome, including the intracranial inflammation process. In acute inflammation, recruitment of a high number of polymorphonuclear (PMN) cells can cause edema which may eventually increase the intracranial pressure. This increase in intracranial pressure may lead to functional decline, disability, and even death. This study aimed to explore the association between the PMN percentage in cerebrospinal fluid (CSF) and TB meningitis patient outcome as measured by the Glasgow Outcome Scale at Dr. Hasan Sadikin General Hospital Bandung, which is a tertiary hospital in Indonesia. This was a retrospective cohort study using patient medical record data from 2017. All TB meningitis patients over 18 years old were included. Patients with missing PMN results in medical record were excluded, which led to a total 88 subjects participating in this study. Variables analyzed were PMN percentage in CSF and patient outcome that were categorized as poor, moderate, and good. Analysis were performed using theKruskal-wallis test. An increase in PMN median as the patient outcome declined were observed, but the association between the PMN percentage in CSF and patient outcome was insignificant (p=0.186). Hence, no association between PMN percentage in CSF and TB meningitis patient outcome was identified in this study. Hubungan Persentase Sel Leukosit Polimorfonuklear dalam Cairan Serebrospinal dan Luaran Pasien Meningitis Tuberkulosis di RSUP Dr. Hasan Sadikin BandungMeningitis tuberkulosis (TB) merupakan merupakan jenis TB ekstraparu paling berat dengan morbiditas dan mortalitas tinggi. Berbagai faktor memengaruhi luaran pasien, salah satunya proses inflamasi intrakranial. Pada inflamasi akut, terjadi peningkatan sel polimorfonuklear (PMN) dan bila dalam jumlah tinggi dapat menimbulkan efek edema yang meningkatkan tekanan intrakranial. Peningkatan tekanan intrakranial ini menyebabkan penurunan fungsi otak, disabilitas, bahkan kematian. Penelitian ini bertujuan mengetahui hubungan persentase PMN dalam cairan serebrospinal (CSS) dan luaran Glasgow Outcome Scale pada pasien meningitis TB di RSUP Dr. Hasan Sadikin Bandung. Penelitian ini merupakan studi retrospektif cohort menggunakan data rekam medik tahun 2017. Kriteria inklusi adalah pasien terdiagnosis meningitis TB dan berusia ≥18 tahun. Kriteria eksklusi adalah data rekam medik yang tidak lengkap untuk hasil PMN. Variabel yang diteliti adalah persentase PMN dan luaran pasien yang dikategorikan menjadi GOS buruk, sedang, dan baik kemudian dianalisis dengan uji Kruskal-wallis. Didapatkan 88 subjek yang memenuhi syarat. Terdapat peningkatan median PMN seiring derajat perburukan luaran namun hasil analisis menunjukkan tidak terdapat hubungan yang bermakna antara PMN dan luaran GOS pasien (p=0,186). Simpulan, tidak terdapat hubungan antara persentase PMN dalam CSS dengan luaran GOS pasien meningitis TB.Meningitis TB (MTB) merupakan infeksi selaput otak dan merupakan jenis TB ekstraparu paling berat dengan tingkat morbiditas dan mortalitas tinggi. Berbagai faktor memengaruhi luaran pasien, salah satunya proses inflamasi. Pada inflamasi akut, terjadi rekrutmen dari sel polymorphonuklear (PMN) dan bila dalam jumlah tinggi dapat menimbulkan efek edema yang pada otak dibatasi tengkorak. Hal ini memungkinkan adanya peningkatan tekanan intrakranial yang dikhawatirkan memengaruhi fungsi otak dengan penurunan fungsi, disabilitas, bahkan kematian. Penelitian ini bertujuan untuk mengetahui hubungan PMN dalam cairan serebrospinal dan luaran Glasgow Outcome Scale pada pasien MTB di RSUP Dr. Hasan Sadikin, Bandung. Metode penelitian dengan studi retrospektif cohort menggunakan data rekam medik tahun 2017. Kriteria inklusi adalah pasien terdiagnosis MTB dan berusia ≥18 tahun. Kriteria eksklusi adalah data rekam medik yang tidak lengkap untuk hasil PMN. Variabel yang diteliti adalah PMN dan luaran pasien yang dikategorikan menjadi GOS buruk, sedang, dan baik kemudian dianalisis dengan uji Kruskal-wallis. Didapatkan 88 subjek yang memenuhi kriteria inklusi. Ditemukan bahwa terdapat peningkatan median PMN seiring penurunan luaran namun hasil analisis menunjukkan tidak terdapat hubungan yang bermakna secara statistik antara PMN dan luaran GOS pasien (p=0,186). Kesimpulan penelitian adalah tidak terdapat hubungan antara PMN dalam CSS dengan luaran GOS pasien MTB
Factors Influencing the Cervical Cancer Screening uptake among Medical Lecturers at Faculty of Medicine Universitas Padjadjaran
Get PDFBackground: Cancer is the leading cause of death worldwide. In Indonesia, cervical cancer is one of the most occurring types of cancer. It is acknowledged that early screening can prevent cervical cancer. This study aimed to explore what factors influenced the screening uptake and to correlate characteristics, perceived susceptibility, and self-efficacy of Pap smear uptake among medical faculty lecturers.Methods: This was a cross-sectional analytical study conducted among female lecturers in the Faculty of Medicine, Universitas Padjadjaran from October to November 2013. The questionnaire was used to collect data using a purposive sampling method. Data collected were tabulated into frequency and percentage and the correlation was performed using Pearson chi-square. Results: From a total of 79 respondents who participated, only 55.7% of medical lecturers had ever taken Pap smear. Reasons for not taking Pap smear were time (77.1%) and the perception of not being at risk (22.9%). However, most of the respondents (84.8%) were willing to have a screening test for cervical cancer routinely. There was a significant correlation between age (p=0.001), level of education (p=0.003) and duration of marriage (p=0.001) with the uptake of Pap smear.Conclusions: The factors that are influencing the uptake of screening are not having the time to take the test and the perception of not being at risk of the disease. There is a correlation between age, level of education and duration of marriage with screening uptake. Awareness of the importance of screening should also be promoted among female doctors
Antibacterial Effect of Human Milk against Streptococcus pyogenes: an in vitro Study
Get PDFBackground: Streptococcus pyogenes infection is one of the common upper respiratory infections among children. Human milk has antibacterial properties that may play a role against infections. The study was conducted to observe the antibacterial effect of human milk against Streptococcus pyogenes.Methods: This was an in vitro experimental study conducted on October–November 2012 in Microbiology Laboratory, Faculty of Medicine, Universitas Padjadjaran, Bandung, using agar well diffusion method. Human milk was collected from eligible donors and tested at concentrations of 70%, 80%, 90%, and 100% dilution with water. Inhibition zone formed surrounding the wells were measured after 24 hours of incubation.Results: All samples incubated with human mils (in concentration of 70%, 80%, 90% and 100%) inhibited the growth of Streptococcus pyogenes, with the inhibition zone mean diameters of 26.33, 28.00, 28.00 and 28.33mm, respectively, compared to the well containing sterile aquadest that did not show any zone of inhibition.Conclusions: Human milk has an in vitro antibacterial effect against Streptococcus pyogenes. Giving human milk to babies is important for preventing infectious diseases
Profile of Upper Extremities Function among Stroke Outpatients in Dr. Hasan Sadikin General Hospital, Bandung
Get PDFBackground: Stroke is one of the leading causes of death and disabilities worldwide. Among all types of disabilities, disturbance in upper extremities functions is at the highest percentage. This study aimed to determine the profile of upper extremities function among stroke outpatients in Dr. Hasan Sadikin General Hospital as an initial step to provide a better follow up and management.Methods: The design of this study was a descriptive study, conducted from April to October 2014 among stroke outpatients in the Department of Physical Medicine and Rehabilitation Dr Hasan Sadikin General Hospital, Bandung based on a consecutive sampling method. The function of upper extremities was tested by Chedoke Arm and Hand Integrated version 9 (CAHAI-9).Result: In total, 42 patients were included, consisting of a male (n=25) and a female (n=17). Nine tasks were performed with dependently by the patients such as open the coffee jar (n22; 52%), call 118 (n24;57%), draw a line with a ruler (n22;52%), pour a glass of water (n33;79%), wring out washed cloth (n26;62%) do up five-button (n31;74%), dry back with the towel (n25;60%), put toothpaste on a toothbrush (n25;60%), and cut medium resistance putty(n32;76%).Conclusions: The majority of stroke outpatients in the sub-acute phase still have a dependent function of upper extremities. Better patient management and interventions focusing on this function need to be enhanced for a better outcome.
Case Study on Cardiac Decompensation in Patients with Preeclampsia and Peripartum Cardiomyopathy
Get PDFIn pregnant women, cardiovascular complications are among the causes of maternal death, one of which is peripartum cardiomyopathy (PPCM). The similarity in the mechanism of PPCM and pre-eclampsia makes preeclampsia a risk factor for PPCM. Preeclampsia, together with PPCM, also contributes to the increasing maternal mortality when most of the causes of maternal death are preventable. This case study aimed to provide descriptions as the basis in education, raising public awareness, early detection, and early treatment, especially for patients at risk. Eight PPCM cases with preeclampsia were identified during the period of 2017–2018 in Dr. Hasan Sadikin General Hospital Bandung, Indonesia (RSHS). Cases of PPCM with preeclampsia are rarely reported in RSHS. Out of 8 patients, 7 experienced severe preeclampsia and 1 had impending eclampsia. Diagnosis in PPCM patients requires a complete history taking, physical examination, and other diagnostic tests such as echocardiography. In this study, all patients (100%) complained of dyspnea on exertion as a chief complaint and, based on the New York Heart Association in 1994, 87.5% were included in functional class III-IV. The average ejection fraction was shown to be 34.6%, indicating a value below normal limit. Studi Kasus Dekompensasi Jantung pada Pasien Preeklampsia dengan Kardiomiopati PeripartumPada wanita hamil, komplikasi kardiovaskular berperan dalam kematian ibu, salah satunya adalah kardiomiopati peripartum (PPCM). Persamaan patogenesis antara PPCM dan pre-eklampsia menjadikan preeklampsia sebagai faktor risiko untuk PPCM. Preeklampsia bersama dengan PPCM berperan dalam peningkatan angka kematian ibu (AKI) ketika sebagian besar penyebab AKI dapat dicegah. Studi kasus ini bertujuan diharapkan untuk memberikan deskripsi sebagai dasar dalam pendidikan, meningkatkan kesadaran masyarakat, deteksi dini, dan perawatan dini, terutama untuk pasien yang berisiko. Pada tahun 2017–2018, terdapat 8 kasus pasien PPCM dengan preeklampsia yang dirawat di RSUP Dr. Hasan Sadikin Bandung (RSHS). Kasus PPCM dengan preeklampsia jarang dilaporkan di RSHS. Dari 8 pasien, 7 mengalami preeklamsia berat dan 1 mengalami eklampsia yang akan datang. Diagnosis pada pasien PPCM memerlukan anamnesis yang lengkap, pemeriksaan fisik, dan pemeriksaan penunjang seperti ekokardiografi. Pada penelitian ini, semua pasien (100%) mengeluhkan sesak nafas sebagai keluhan utama dan berdasar atas klasifikasi New York Heart Association tahun 1994, 87.5% termasuk dalam kelas fungsional III-IV. Rata-rata fraksi ejeksi menunjukkan 34.6% yang menandakan nilai di bawah batas normal
PENGARUH PEMBERIAN MINUMAN KARBOHIDRAT (MALTODEXTRIN 12,5%) PRAOPERASI TERHADAP KEJADIAN MUAL DAN MUNTAH PASCAMASTEKTOMI
Get PDFMual dan muntah pascaoperasi (postoperative nausea and vomiting, PONV) menjadi masalah yang umum terjadi setelah operasi mastektomi dengan angka kejadian berkisar 21–92%. Pemberian minuman karbohidrat (CHO) praoperasi ditawarkan sebagai sebuah solusi menurunkan PONV dan juga merupakan salah satu komponen penting dan disarankan untuk mencapai enhanced recovery after surgery (ERAS). CHO berhubungan dengan penurunan katabolisme dan resistensi insulin pascaoperasi. Penelitian ini bertujuan mengetahui pengaruh pemberian minuman berkarbohidrat (CHO) oral sebelum operasi terhadap tingkat kejadian PONV pascaoperasi mastektomi. Penelitian menggunakan eksperimental uji acak buta tunggal di Rumah Sakit Dr. Hasan Sadikin (RSHS) Bandung pada November 2019–Februari 2020. Sebanyak 46 pasien dibagi menjadi dua kelompok, yakni kelompok K (kelompok kontrol, air mineral, n=23 subjek) dan kelompok C (kelompok CHO, n=23 subjek). Analisis data hasil penelitian dilakukan dengan Uji Mann-hitney. Kejadian mual muntah pada kelompok kontrol lebih besar dibanding dengan kelompok CHO pada menit 0–30 (57% vs 22%), pada menit 30–60 (91% vs 61%), dan pada menit 60–120 (78% vs 61%) dengan perbedaan yang bermakna (p<0,05). Simpulan, pemberian minuman karbohidrat praoperasi dapat menurunkan kejadian mual muntah pascamastektomi dibandingkan dengan kelompok kontrol. Effect of Preoperative Oral Carbohydrate Supplementation (Maltodextrin 12.5%) on Post-Mastectomy Nausea and Vomiting Incidence Postoperative nausea and vomiting (PONV) is a common problem after surgery. Mastectomy is one of surgeries with a high-risk for PONV, which is seen in 21–92% of the patients. Preoperative carbohydrate (CHO) drinks are offered to reduce PONV. The provision of CHO is also important as it is recommended to obtain enhanced recovery after surgery (ERAS). CHO is associated with reduced catabolism and postoperative insulin resistance. This study aimed to determine the effect of oral carbohydrate (CHO) drinks before surgery on the incidence of postoperative PONV in mastectomy. This was an experimental single-blind randomized study conducted in Dr. Hasan Sadikin General Hospital (RSHS) Bandung, Indonesia. A total of 46 patients were divided into two groups, namely group K (control group, mineral water, n=23 subjects) and group C (CHO group, n=23 subjects). Data collected were then analyzed using the Mann Whitney test and the results showed that during PONV incidence rates were significantly higher 0–30 minutes after the surgery (57% vs 22%), 30–60 minutes after the surgery (91% vs 61%), and 60–120 minutes (78% vs 61%) (p < 0.05). Therefore, the administration of preoperative carbohydrate drinks can reduce the incidence of postoperative nausea and vomiting in mastectomy. Mual dan muntah pascaoperasi (postoperative nausea and vomiting, PONV) menjadi masalah yang umum terjadi setelah operasi mastektomi dengan angka kejadian berkisar 21 hingga 92%. Pemberian minuman karbohidrat (CHO) praoperasi ditawarkan sebagai sebuah solusi menurunkan PONV dan juga merupakan salah satu komponen penting dan disarankan untuk mencapai ERAS (enhanced recovery after surgery). CHO berhubungan dengan berkurangnya katabolisme dan resistensi insulin pascaoperasi. Penelitian ini bertujuan mengetahui pengaruh pemberian minuman berkarbohidrat (CHO) oral sebelum operasi terhadap tingkat kejadian PONV pascaoperasi mastektomi. Penelitian menggunakan eksperimental uji acak buta tunggal di Rumah Sakit Dr. Hasan Sadikin (RSHS) Bandung pada November 2019 hingga Februari 2020. Sebanyak 46 pasien dibagi menjadi dua kelompok, yakni kelompok K (kelompok kontrol, air mineral, n = 23 subjek) dan kelompok C (kelompok CHO, n = 23 subjek). Analisis data hasil penelitian dilakukan dengan Uji Mann Whitney. Kejadian mual muntah pada kelompok kontrol lebih besar dibanding dengan kelompok CHO pada menit 0-30 (57% vs 22%), pada menit 30-60 (91% vs 61%) dan pada menit 60-120 (78% vs 61%) dengan perbedaan yang bermakna (p<0,05). Simpulan penelitian adalah pemberian minuman karbohidrat praoperasi dapat menurunkan kejadian mual muntah pascamastektomi dibandingkan dengan Kelompok Kontrol.
Correlation Between Tumor Cell Differentiation and CEA Levels in Patients with Adenocarcinoma of the Rectum
Get PDFAdenocarcinoma of the rectum is the most common colorectal cancer in Indonesia. This cancer has the highest recurrence after curative surgical therapy with or without adjuvant therapy. With the advancing modern histopathology and molecular biology, the prognosis after therapy can be predicted through surveillance using tumor cell differentiation and carcinoembryonic antigen (CEA). The aim of this study was to analyze the correlation between tumor cell differentiation and serum CEA level in patients with adenocarcinoma of the rectum in Dr. Hasan Sadikin General Hospital Bandung, Indonesia. This was a retrospective observational analytic study conducted from January 2018- January 2019. There were 36 patients involved in this study consisting of 3 patients (8.3%) diagnosed with Stage II, 10 patients (27.7%) with Stage IIIA, 20 patients (55.5%) with stage IIIB, and 3 patients (8.3%) with stage IIIC. On histopathological examination, it was demonstrated that19 patients (52.8%) were well-differentiated, 15 patients (41.7%) were moderately differentiated, and 2 patients (5.6%) were poorly differentiated. The mean CEA level (CI 95%) for well-differentiated patients before surgery was 138.18 (15.99-260.38) ng/ml while the same level for the moderately differentiated patients was 64.34 (34.34-163.02) ng/ml. The mean CEA level for poorly differentiated patients was 1.55 (6.71-9.81) ng / ml. The result of the Kruskal Wallis test showed a p-value of 0.004. There is a strong correlation between the level of tumor cell differentiation and CEA level. Hubungan Tingkat Diferensiasi Sel Tumor dengan Kadar Ekspresi CEA Pada Pasien Adenokarsinoma Rektum Di Indonesia adenokarsinoma rektum memiliki rekurensi yang tinggi setelah terapi bedah kuratif dengan atau tanpa terapi adjuvan. Prognosisnya setelah terapi dapat diketahui melalui surveilens dengan menggunakan Tingkat diferensiasi sel tumor dan carcinoembryonic antigen (CEA). Penelitian ini bertujuan menilai hubungan diferensiasi sel tumor dengan tingkat ekspresi CEA pada pasien adenokarsinoma rektum di RSUP Dr. Hasan Sadikin Bandung. Penelitian ini merupakan penelitian analitik observasional secara retrospektif. Pengambilan data dilakukan dari rekam medik Poliklinik Bedah Digestif dengan diagnosa adenokarsinoma rektum. Dari 36 pasien, 3 pasien (8,3%) stadium II, 10 pasien (27.7%) Stadium IIIA, 20 pasien (55,5%) stadium IIIB dan 3 pasien (8,3%) sisanya stadium IIIC. Sebanyak 19 pasien (52.8%) memiliki hasil histopatologi well differentiated, 15 pasien (41.7%) moderately differentiated dan 2 pasien (5.6%) poorly differentiated. Mean (CI 95%) kadar CEA sebelum operasi untuk well differentiated adalah 138.18(15.99-260.38) ng/mL, moderately differentiated 64.34(34.34-163.02)ng/ml, poorly differentiated 1.55(6.71-9.81)ng/mL. Uji Kruskal Wallis didapatkan nilai p=0,004 sehingga dapat disimpulkan bahwa terdapat hubungan antara tingkat diferensiasi sel tumor dengan kadar CEA serum sebelum terapi pada pasien adenokarsinoma rektum di RSUP Hasan Sadikin Bandung. Pasien adenokarsinoma rektum preoperatif di RSUP Hasan Sadikin Bandung menunjukkan bahwa semakin baik tingkat diferensiasi sel tumornya semakin tinggi kadar CEAnya di dalam serum
Relationship between Nomophobia and Attention among Medical Students in Jakarta
Get PDFBackground: The advancements in technology in the form of smartphones have made life easier; however, some negative effects have been recorded with regards to the use of smartphone. Among these negative effects are nomophobia, or a phobia of no mobile phone, and lack of attention. This study explored the relationship between nomophobia and attention in medical students.Methods: This was a cross-sectional analytic study on medical students in Jakarta in 2019. The Nomophobia Questionnaire (NMP-Q) was used to measure the level of nomophobia and the Six Letter Cancellation Test (SLCT) was used to measure attention. Data collected were analyzed using a simple linear regression test.Result: There was a weak negative relationship between the severity of nomophobia and attention (r=.161). However, nomophobia score was a very weak predictor for attention with an adjusted r-squared score of .021.Conclusions: Nomophobia does not necessarily affect the attention of medical students. Excessive mobile phone use does cause nomophobia and lack of attention. Therefore, smartphones need to be used wisely.