727 research outputs found
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Printing and Erasing of DNA-based Photoresists inside Synthetic Cells [RESEARCH DATA]
No full textIn the pursuit to produce functioning synthetic cells from the bottom up, DNA nanotechnology has proven to be a powerful tool.
However, the crowded yet highly organized arrangement in living cells, bridging from the nano- to the micron-scale, remains challenging to recreate with DNA-based architectures. Here, laser microprinting is established to print and erase shape-controlled DNA hydrogels inside the confinement of water-in-oil droplets and giant unilamellar lipid vesicles (GUVs). The DNA-based photoresist consists of a photocleavable inactive DNA linker which interconnects Y-shaped DNA motifs when activated by local irradiation with a 405 nm laser. An alternative linker design allows to erase custom features from a preformed DNA hydrogel with feature sizes down to 1.38um. The present work demonstrates that the DNA hydrogels can serve as an internal support to stabilize non-spherical GUV shapes. Overall, DNA-based photoresists for laser printing in confinement allow to build up architectures on the interior of synthetic cells with light, which diversifies the toolbox of bottom-up synthetic biology
Cyclopentannulated Dihydrotetraazapentacenes [Data]
No full textThe transition-metal catalyzed cyclization of bissilylethynylated N,N’-dihydro¬tetra¬aza¬pentacene (TIPS-TAP-H2) into bissilylated cyclo¬penta¬[fg,qr]¬pentacenes is reported. Depending on the catalyst either none, one or two silyl groups migrate and change their positions in the formed five-membered rings. The optoelectronic properties are quite similar, whereas the packing motifs differ dramatically. Control experiments and quantum chemical calculations were performed to investigate the mechanism of the reaction and the selectivity of the silyl shift
The Creation of Social Norms under Weak Institutions [Data and Replication Package]
No full textThese data, code, and documents replicate all analyses in "The Creation of Social Norms under Weak Institutions?" by Florian Diekert, Tillmann Eymess, Joseph Luomba, and Israel Waichman, in the Journal of the Association of Environmental and Resource Economists (JAERE)
Climate signals in stable carbon and hydrogen isotopes of lignin methoxy groups from southern German beech trees [data]
No full textStable hydrogen and carbon isotope ratios of wood lignin methoxy groups (δ13CLM and δ2HLM values) have been shown to be reliable proxies of past temperature variations. Previous studies showed that δ2HLM values even work in temperate environments where classical tree-ring width and maximum latewood density measurements are less successful. Here, we analyse annually resolved δ13CLM values from 1916-2015 of four beech trees (Fagus sylvatica) from a temperate site near Hohenpeißenberg in southern Germany and compare these data with regional to continental scale climate observations. Initial δ13CLM values were corrected for the Suess effect (a decrease of δ13C in atmospheric CO2) and physiological tree responses to increasing atmospheric CO2 concentrations considering a range of published discrimination factors. The calibration of δ13CLM chronologies against instrumental data reveals highest correlations with regional summer (r = 0.68) and mean annual temperatures (r = 0.66), as well as previous-year September to current-year August temperatures (r = 0.61), all calculated from 1916-2015 and reaching p 0.05). The new δ13CLM chronologies were finally compared with previously produced δ2HLM values of the same trees to evaluate the additional gain of assessing past climate variability using a dual-isotope approach. Compared to δ13CLM, δ2HLM values correlates substantially stronger with large-scale temperatures averaged over western Europe (rprev.Sep-Aug = 0.69), whereas only weak and mainly insignificant correlations are obtained between precipitation and both isotope chronologies (δ13CLM and δ2HLM values). Our results indicate great potential of using δ13CLM values from temperate environments as a proxy for local temperatures, and in combination with δ2HLM values, to assess regional to sub-continental scale temperature patterns
JJ-model isochrone set: PARSEC, MIST, and BaSTI stellar evolution
No full textThis dataset contains three alternative isochrone grids generated by different stellar evolution codes - PARSEC (Padova), MIST, and BaSTI. Grids cover a wide range of metallicities from approx. -2.6 to +0.5 (60-62 individual metallicities) and ages from 0 to 13 Gyr with a fine step of 50 Myr. Included photometric systems are UBVRIJHK+Gaia_DR2+Gaia_EDR3 (Padova), UBVRI+2MASS+Gaia_DR2+Gaia_EDR3 (MIST), and Gaia_EDR3 (BaSTI).
Isochrone grids are part of the python package
jjmodel
Semantische Datenmodellierung für Werkverzeichnisse (Universitätsbibliothek Heidelberg)
No full textDie Semantische Datenmodellierung für Werkverzeichnisse war einer der Schwerpunkte des von der Deutschen Forschungsgemeinschaft (DFG) geförderten Projektes "Semantics4Art&Architecture - Aufbau einer nachhaltigen Forschungsinfrastruktur für die ontologiebasierte Dokumentation und Erschließung von Kunst und Architektur" (2018-2021).
Im Rahmen des Projektes wurden u.a. die Heidelberger Anwendungsontologie für Werkverzeichnisse und das Heidelberger Werkverzeichnis-Template im WissKI-Pathbuilder entwickelt.
Die Anwendungsontologie ist eine Erweiterung des CIDOC Conceptual Reference Model (ISO 21127), umgesetzt im Erlangen CRM / OWL (Version 200717). Sie bietet Klassen und Eigenschaften, die zur Beschreibung von Kunstwerken für ein Werkverzeichnis oder Catalogue raisonné konkretisiert sind. Sie kann darüber hinaus zur Modellierung eines Datenmodells benutzt werden, dessen Fokus unabhängig vom Kontext Werkverzeichnis ganz allgemein auf der Dokumentation und Tiefenerschließung von Kunstwerken liegt. Über den folgenden Weblink kann die aktuelle Version (current Version) aufgerufen und unter Berücksichtigung der Lizenz CC-BY-SA 4.0 (Rechteinhaber: Universitätsbibliothek Heidelberg) nachgenutzt werden: http://lod.ub.uni-heidelberg.de/ontologies/werkverzeichnis/
Ergänzungen von Klassen und Eigenschaften durch die Universitätsbibliothek Heidelberg sind möglich. Beachten Sie dazu die Angaben zur Versionshistorie (priorVersion). Da in der Anwendungsontologie nur additive Änderungen erfolgen, ist eine Rückwärtskompatibilität garantiert.
Unter Einsatz der Heidelberger Anwendungsontologie für Werkverzeichnisse wurde das Heidelberger Werkverzeichnis-Template im WissKI-Pathbuilder respektive Datenmodell entwickelt, welches eine detaillierte wissenschaftliche Erschließung bietet. Der Forschungsschwerpunkt muss dabei nicht zwangsläufig ein Werkverzeichnis sein, vielmehr kann das Template ganz allgemein für Dokumentationen von Kunstwerken, ihre Identifikation, Klassifikation, Beschreibung und/oder Rezeption verwendet werden.
Das Dataset umfasst:
Heidelberger Anwendungsontologie für Werkverzeichnisse (OWL)
Heidelberger Anwendungsontologie für Werkverzeichnisse (Dokumentation) (PDF)
Heidelberger Werkverzeichnis-Template im WissKI-Pathbuilder (XML)
Heidelberger Werkverzeichnis-Template im WissKI-Pathbuilder (PDF)
Heidelberger Werkverzeichnis-Template im WissKI Pathbuilder - Ergänzende und alternative Modellierungen (PDF)</p
Synthesis of CT images from digital body phantoms using CycleGAN [dataset]
No full textThe potential of medical image analysis with neural networks is limited by the restricted availability of extensive data sets. The incorporation of synthetic training data is one approach to bypass this shortcoming, as synthetic data offer accurate annotations and unlimited data size. We evaluated eleven CycleGAN for the synthesis of computed tomography (CT) images based on XCAT body phantoms
Ergänzungsmaterial zu: Das Kampfareal von Kalkriese. Fallstudie einer antiken Konfliktlandschaft
No full textSupplementary figures 4, 24, 41 & 5
The CSY-protecting group in the microwave-assisted synthesis of aggregation-prone peptides [Research Data]
No full textThis report describes the application of cyanosulfurylide (CSY)-protected aspartatic acid building blocks in microwave-assisted synthesis of aggregation-prone protein domains. We present a synthesis of Fmoc-Asp(CSY)-OH on a multigram scale, as well as procedures for the microwave-assisted synthesis of CSY-protected peptides, and CSY cleavage in partially folded or aggregation-prone peptides
Ground Truth data for printed Devanagari
No full textGround truth (GT) data (jpg and alto xml files) for an OCR model that recognizes printed text in Devanagari script.
The GT data was trained on Transkribus with the HTR+ engine. The training was performed on appr. 220 pages with appr. 27,000 words. The validation set was 10% of the training set.
The training material is comprised of letterpress printings from the Naval Kishore Press (Lakhnau, North India) from the late 19th and early 20th century in the Hindi, Sanskrit, Braj Bhasha and Awadhi languages.
Transcription was performed by Nicole Merkel-Hilf (CATS Library / Heidelberg University Library) with support by Daria Peshcherova (CATS Library / Heidelberg University Library)