727 research outputs found
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Designing Sustainable Polymers: Lactate Esters for 3D Printing and Upcycling [data]
No full textThe search for sustainable polymer systems is key to tackling the current climate crisis. However, the use of bio-based polymers does not suffice to achieve this goal. Additionally, new chemical approaches enabling the re- or upcycling of polymer materials need to be explored. Herein, we exploit lactate esters with different substituents as readily available bio-based molecules for the synthesis of printable monomers. The synthesis of these lactate ester-based monomers follows green chemistry principles by establishing a solvent-free, one-pot approach, relying on a reusable catalyst, and achieving high conversions (84 – 100%) at mild conditions. Further, these monomers are utilized in 3D printable ink formulations for digital light processing (DLP) for the first time in combination with a recycled crosslinker. The resulting 3D printed structures display complex geometries with high resolution. A key attribute of the presented system is that the 3D printed polymer material can be upcycled via aminolysis affording a pre-cursor of the crosslinker, which is in turn
incorporated into the further ink formulations, introducing a material circularity into the system. These results demonstrate a powerful approach by combining bio-based monomers and chemical upcycling with sustainable 3D printing techniques
Jing bao ground truth – text block crops and annotations
No full textThis is the data set related to the paper "Language Model Assisted OCR Classification for Republican Chinese Newspaper Text", JDADH 11/2023. In this work, we present methods to obtain a neural optical character recognition (OCR) tool for article blocks in a Republican Chinese newspaper.
The dataset contains two subsets:
The pairs of text block crops and corresponding ground truth annotations from April 1920, 1930 and 1939 of the Jingbao newspaper (jingbao_annotated_crops.zip).
The labeled images of single characters which we automatically cropped from the April 1939 issues of the Jingbao using separators generated from projection profiles (jingbao_char_imgs.zip).</p
Tool for Extracting PP Attachment Disambiguation Dataset
No full textThis resource contains code to extract a PP attachment disambiguation dataset as described in the paper: Do and Rehbein (2020). "Parsers Know Best: German PP Attachment Revisited".
The input is in CoNLL format, and the output format is similar to the one described in de Kok et al. (2017).</p
Codices Palatini latini - Humanistische, Triviums- und Reformationshandschriften
No full textHere you can find the descriptions of the Latin Palatine manuscripts as published in the manuscripts catalog "Die humanistischen, Triviums- und Reformationshandschriften der Codices Palatini Latini in der Vatikanischen Bibliothek (Cod. Pal. lat. 1461-1914)", edited by Wolfgang Metzger, with contributions by Veit Probst, Wiesbaden 2002 (Kataloge der Universitätsbibliothek Heidelberg 4). The description for each manuscript was subsequently recorded as TEI-XML file by XML encoding in accordance with TEI-P5 using GND standard vocabulary.These TEI files follow an outdated TEI schema originally developed at the Herzog August Bibliothek Wolfenbüttel and contain some ad hoc solutions which were chosen pragmatically in Heidelberg and which do not always comply with the TEI Guidelines. A future migration of the dataset into a fully TEI-compliant format is considered as desirable
Prefrontal engrams of long-term fear memory and pain
No full textThis dataset contains electrophysiological spike time data and associated analysis procedures as well as image analysis scripts reported in Stegemann et al. Prefrontal engrams of long-term fear memory perpetuate pain perception. Nature Neuroscience (2023). Abstract: A painful episode can lead to life-long increase in an individual’s experience of pain. Fearful anticipation of imminent pain could play a role in this phenomenon, but the neurobiological underpinnings are unclear, since fear can both suppress and enhance pain. Here, we show in mice that long-term associative fear memory stored in neuronal engrams in the prefrontal cortex (PFC) determines whether a painful episode shapes pain experience later in life. Furthermore, in conditions of inflammatory and neuropathic pain, prefrontal fear engrams expand to encompass neurons representing nociception and tactile sensation, leading to pronounced changes in prefrontal connectivity to fear-relevant brain areas. Conversely, silencing prefrontal fear engrams reverses chronically established hyperalgesia and allodynia. These results reveal that a discrete subset of PFC neurons can account for the debilitating comorbidity of fear and chronic pain and show that attenuating the fear memory of pain can alleviate chronic pain itself
Two Dimensional Triptycene End-Capping and Its Influence on the Self-Assembly of Quinoxalinophenanthrophenazines [Data]
No full textA series of quinoxalinophenanthrophenazines (QPPs) with two-dimensional triptycene end-caps was synthesized from a triphenylene base ortho-diamine. UV/vis spectroscopy suggested the formation of dimers in solution which was further confirmed by MALDI-TIMS-TOF-MS and single crystal X-ray diffraction analysis. By the latter, the dimer formation attributed to short π-interactions and a perfect shape-match in one case
Semi-supervised water tank detection to support vector control of emerging infectious diseases transmitted by Aedes Aegpyti [Research Data]
No full textWATER TANK DETECTION MODEL OF JOURNAL PAPER (Semi-supervised water tank detection to support vector control of emerging infectious diseases transmitted by Aedes Aegypti)
The disease transmitting mosquito Aedes Aegypti is an increasing global threat. It breeds in small artificial containers such as rainwater tanks and can be characterized by a short flight range. The resulting high spatial variability of abundance is challenging to model. Therefore, we tested an approach to map water tank density as a spatial proxy for urban Aedes Aegypti habitat suitability. Water tank density mapping was performed by a semi-supervised self-training approach based on open accessible satellite imagery for the city of Rio de Janeiro. We ran a negative binomial generalized linear regression model to evaluate the statistical significance of water tank density for modeling inner-urban Aedes Aegypti distribution measured by an entomological surveillance system between January 2019 and December 2021. Our proposed semi-supervised model outperformed a supervised model for water tank detection with respect to the F1-score by 22%. Water tank density was a significant predictor for the mean eggs per trap rate of Aedes Aegypti. This shows the potential of the proposed indicator to enrich urban entomological surveillance systems to plan more targeted vector control interventions, presumably leading to less infectious rates of dengue, zika, and chikungunya in the future
Diagnostic performance of host protein signatures as a triage test for active pulmonary TB [data]
No full textThe current four symptom screen recommended by the WHO is widely used as screen to initiate diagnostic testing for active pulmonary tuberculosis (TB), yet the performance is poor especially when TB prevalence is low. In contrast, more sensitive molecular tests are less suitable for placement at primary care level in low resource settings. In order to meet the WHO End TB targets new diagnostic approaches are urgently needed to find the missing undiagnosed cases. Proteomics-derived blood host biomarkers have been explored because protein detection technologies are suitable for the point-of-care setting and could meet cost targets.
This study aimed to find a biomarker signature that fulfills WHO’s target product profile (TPP) for a TB screening. 12 blood-based protein biomarkers from three sample populations (Vietnam, Peru, South Africa) were analyzed individually and in combinations via advanced statistical methods and machine learning algorithms. The combination of I-309, SYWC and kallistatin showed the most promising results to discern active TB throughout the datasets meeting the TPP for a triage test in adults from two countries (Peru and South Africa). The top performing individual markers identified at the global level (I-309 and SYWC) were also among the best performing markers at country level in South Africa and Vietnam.
This analysis clearly shows that a host protein biomarker assay is feasible in adults for certain geographical regions based on one or two biomarkers with a performance that meets minimal WHO TPP criteria
Real-World PP Attachment Disambiguation Dataset
No full textThis resource contains a German dataset for real-world PP attachment disambiguation.
The creation, analysis and experiment results of the dataset are described in the paper: Do and Rehbein (2020). "Parsers Know Best: German PP Attachment Revisited"</p
Country‐Specific Participation Patterns in Transnational Governance Initiatives on Sustainability [Dataset]
No full textContains data on transnational governance initiaties on sustainability. The data is self coded on the based of information provided by the tansnational governance initiatives on their respective websites