Advanced Emergency Medicine (E-Journal)
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Rapid Recognition and Management of Critical Illnesses in Emergency Medicine
Get PDFAs an important part of clinical medicine, emergency medicine bears the important responsibility of rapid identification and effective treatment of patients with acute and critical illnesses. The purpose of this paper is to discuss the rapid identification of critical illnesses in
emergency medicine and its treatment strategy, through the analysis of vital signs monitoring, identification of acute and critical symptoms,
first aid skills and operation standards, etc., to provide emergency physicians with a set of scientific and systematic response program, with a
view to improving the efficiency of emergency treatment and patient survival rate
Construction of a Risk Prediction Model for Postpartum Stress Urinary Incontinence Based on Machine Learning
Get PDFPregnancy pregnancy and childbirth is one of the main causes of Stress Urinary Incontinence (SUI). SUI not only affects women's physical health, but also affects women's mental health. 48 puerperae with SUI 6-8 weeks postpartum and 118 puerperae without urinary incontinence during the same period were selected in a hospital in eastern China. Patient information was retrieved from medical records, and postpartum women were asked to complete the International Urinary Incontinence Counseling Questionnaire Short Form (ICI-Q-SF). The early prediction model of SUI was constructed based on the random forest ensemble learning method. Compared with the results of the traditional logistic regression model, the random forest model has better prediction performance and can be used as a screening tool for high-risk groups of SUI during pregnancy to guide clinical work
Clinical Effect of Lobectomy Under Single-Hole Thoracoscope in Minimally Invasive Surgical Treatment of Non-Small Cell Lung Cancer
Get PDFAims: To explore the effect of single-hole thoracoscopic lobectomy in the treatment of non-small cell lung cancer (NSCLC). Methods: A total of 56 patients with NSCLC from the Third People's Hospital of Jinan during May 2020 to May 2022 were selected as the study subjects, which were divided into control group and observation group according to the difference of treatment methods. Three holes thoracoscopic lobectomy was performed in the control group, and single-hole thoracoscopic lobectomy was conducted in the observation group. The operation time, intraoperative bleeding, total number of lymph node dissection, total drainage volume of thoracic duct 3 days after operation, extubation time of thoracic duct, postoperative hospital stays, postoperative pain score (day 1, 3, 7), and postoperative complication rate were compared between the two groups. Results: Compared with the control group, the operation time, postoperative decannulation time and postoperative hospital stay of patients in the observation group were significantly shortened (P<0.05), the amount of intraoperative bleeding and the total drainage volume of thoracic duct 3 days after operation were significantly reduced (P<0.05), and the postoperative pain score and the incidence of postoperative complications were significantly improved (P<0.05). Conclusion: Single-hole thoracoscopic lobectomy is effective and safe in the treatment of non-small cell lung cancer, which is worthy of clinical promotion
Evaluation of the Effect of PETCT in the Examination and Diagnosis of Lymphoma Patients
Get PDFObjective: To analyze the effect of PET in the diagnosis of lymphoma. Methods: 42 patients with lymphoma admitted to our hospital from January 2018 to December 2019 were selected as the study subjects. All patients were examined by ultrasound and PETCT, and the examination results were observed and analyzed. Results: The positive rate of ultrasonic examination was 69.05% (29/42), and the positive rate of PET examination was 78.57% (33/42). There was significant difference between groups (P<0.05); The sensitivity, specificity and accuracy of PETCT in lymphoma patients were 91.67%, 83.33% and 90.48%, respectively. There was significant difference between the two groups (P<0.05). Conclusion: PETCT examination of lymphoma patients has high positive detection rate, sensitivity, specificity and accuracy, and can make accurate diagnosis of the disease
Effect of Rehabilitation Training on Limb Function and Self-Care Ability of Patients with Parkinson's Disease
Get PDFObjective: This study mainly analyzes the effect of rehabilitation training on limb function and self-care ability of Parkinson's disease patients. Methods: 50 patients with Parkinson's disease who were diagnosed and treated in a Shaanxi Provincial People's Hospital in China from February 2, 2018 to July 2, 2021 were tested. These patients were divided into two groups randomly with 25 patients in each group. The control group should adopt routine treatment and nursing intervention, and the experimental group should take the control group as the benchmark and apply rehabilitation exercise training, The limb function and self-care ability of patients in the experimental group were compared with control group before and after the intervention. Results: after the intervention, the patients in the control group, whether Berg balance scale or UPDRS - â…¢ score, will be lower than the patients in the observation group. And after the intervention, the Barthel score of both groups will be better than that before the intervention (P < 0.01). Conclusion: rehabilitation training has a great impact on the limb function and self-care ability of patients with Parkinson's disease. Through the form of rehabilitation exercise training, we can further improve the limb function of current patients, make the self-care ability of patients become higher, and delay the development of the disease
Combination of Chinese and Western medicine in the Treatment of Orthopaedic Diseases
Get PDFObjective: To observe the effect of the combination of Chinese and Western medicine therapy in the clinical treatment of traumatic orthopaedic diseases. Methods: The clinical data of patients with traumatic orthopaedic diseases treated in hospitals between June 2020 and October 2022 were retrospectively collected. 60 cases were taken as the study subjects and divided into a control group (consisting of 30 patients who took conventional Western medicine treatment) and an observation group (consisting of 30 patients who took combined Chinese and Western medicine treatment) with the aid of an Excel sheet to compare the treatment effects. Results: The rates of wound swelling and pain relief in the control group and the observation group were 66.67% and 90.00% respectively, with the observation group having a higher rate (p<0.05); the rates of soft tissue repair in the control group and the observation group were 50.00% and 80.00% respectively, with the observation group having a higher rate (p<0.05); the fracture healing time in the observation group was shorter than that in the control group (p<0.05). Conclusion: The effect of combining Chinese and Western medicine in the treatment of traumatic orthopaedic diseases is ideal, which is mainly reflected in the three aspects of promoting wound swelling, promoting soft tissue recovery and promoting fracture healing, and is worth promoting
Application Study of Nebulized Low-Dose Azithromycin in the Treatment of Community-Acquired Pneumonia
Get PDFObjective: To analyze the effect of nebulized low-dose azithromycin in the treatment of community-acquired pneumonia. Methods: The selected research subjects were 68 patients with community-acquired pneumonia admitted to our hospital from January 2020 to January 2021. The patients were divided into control group and experimental group by random number table method. The control group was treated with normal saline inhalation (34 cases), and the experimental group was treated with aerosol low-dose azithromycin (34 cases). The treatment effects of the two groups were compared. Results: There were significant differences in the effective rates of treatment between the two groups, and the experimental group was higher (P<0.05). There were significant differences in inflammatory cytokine indexes between the two groups, and the experimental group was lower (P<0.05). Conclusion: The treatment effect of low-dose azithromycin in the treatment of patients with community-acquired pneumonia is definite, and it can be applied and promoted in clinical practice
Exploration of Treatment in Patients with T3 Rectal Cancer with EMVI
Get PDFTo explore the clinical efficacy of neoadjuvant chemoradiotherapy, combined with surgery and direct surgery in patients with stage T3 rectal cancer combined with EMVI. Method: The clinical data of patients with extragastrointestinal middle and low rectal cancer in the First Affiliated Hospital of Chongqing Medical University from January 2015 to May 2019 were retrospective reviewed, including 59 patients in the neoadjuvant treatment group (neoadjuvant chemoradiotherapy + surgical treatment) and 71 patients in the direct surgery group. Both groups underwent total rectal total membrane resection. Data and Methods:The concurrent chemotherapy regimens were all included in the XELOX regimen. The RT was performed by IMRT with D T 45 to 50.4 G y, from 1.8 to 2.0 G y each, for 25 to 28 sessions. Perioperative conditions, postoperative pathology and follow-up of the two groups were observed. Results: There was no significant difference in postoperative conditions (gastrointestinal function recovery time, postoperative drainage drainage, postoperative time of drainage removal) between the neoadjuvant treatment group and the direct surgery group (P> 0. 05); The length of postoperative hospital stay was significantly different (P <0.05); No significant operation time occurred between the neoadjuvant treatment group (264 min vs. 239 min) and the surgical group, (P> 0. 05)；The amount of intraoperative bleeding (85.7ml vs.110.0 ml), the number of lymph node dissection (11 vs. 13), the lymph node positive rate (27.12% vs.43.6%) betweenthe neoadjuvant treatment group and the direct surgery group had statistical significant (P＜0. 05); The 3-yearrecurrence-free survival (93.2 %) rate was higher in the neoadjuvant treatment group than in the direct surgery group (74.6 %), which was significant (P <0.05); The 3-year survival rate (98.30,% vs. 85.9 %) was significantly significant (P <0.05); There was no significant difference in the anal preservation rate (71.19% vs. 80.28%) (P> 0. 05). Conclusion: The neoadjuvant chemoradiotherapy improves the recurrence-free survival rate of locally advanced rectal cancer, and has no obvious effect on the postoperative complications rate, anal preservation rate and gastrointestinal function recovery
Global Advances and Frontiers of Phytochemicals in Tumor Research: A Bibliometric Study (2010-2023)
Get PDFObjectives: Analysis of advances, hotspots and frontiers of tumor-related phytochemicals by scientifc bibliometric methods during 2012-2023. Background: Natural phytochemicals are abundantly found in nature and have a wide range of biological activities. Phytochem-icals have been shown to provide both curative and preventive benefts on many chronic diseases such as cancers. Tumor research on phyto-chemicals is one of the felds with the greatest potential for expansion in the world. However, there is still much to explore about the action mechanism of phytochemicals, the efcacy and safety of application in vivo, and the value of clinical practice. Methods: Atotal of 6523 arti-cles on tumor-related phytochemicals were identifed from the Web of Science Core Collection (WOSCC) database for research on tumor-re-lated phytochemicals. The bibliometric analysis was carried out using CiteSpace and the R package “Bibliometrix”. Results: The analysis includes 6523 publications from 144 nations or regions, with China leading the way. The number of annual publications increased rapidly from 2012 to 2022 and reached a maximum in 2022. China published the most articles, followed by India and the United States. There is a wide range of collaborations between countries, with Saudi Arabia and Egypt being the closest partners. LI Y has produced the most research outputs, yet Prof. Liu RH has received the most local citations. Although MOLECULES has the most articles, FOOD CHEMISTRY is the journal with the highest H-index. The main topics include phytochemical mechanisms and clinical applications in carcinogenesis and devel-opment. “Secondary metabolite”, “green synthesis”, “functional food”, and “degradation” all exhibit signifcant citation burstness between 2019-2023. Conclusions: This study is the frst to apply bibliometrics to examine the development of phytochemicals in oncology research over the period 2010-2023, which gives researchers a brief overview of advances, hotspots, and potential future trends in the feld
Research Progress of Mitochondrial DNA and Cancer
Get PDFMitochondrial DNAmutation will lead to a series of diseases, and Defective mitochondrial DNAwill lead to organ dysfunction.The increase of mutation frequency caused by nuclear DNArepair defect, replication error, carcinogen exposure and aging is generally consid-ered to drive the occurrence of cancer.In contrast, the status and role of mitochondrial genome mutation in cancer are not clear.We reviewed the variation in number and structure of mtDNAin colorectal cancer, liver cancer, breast cancer , aiming to illustrate the important role of mtDNAin the occurrence and development of cancer, and to provide some reference for early diagnosis, treatment and prognosis evaluation of cancer