Advanced Emergency Medicine (E-Journal)
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Effects of Ultra-early Intervention on Gross Motor Function in Neonates with Hypoglycemic Brain Injury
Get PDFObjective : To investigate the effect of ultra-early intervention on gross motor function of neonates with hypoglycemic brain injury and evaluate the application value. Methods: we choose thirty four children with hypoglycemic brain injury who hospitalized in the neonatology department of Tai'an City central hospital from January 2017 to December 2019. They were randomly divided into conventional treatment group and ultra-early intervention group, each with 17 people. The conventional treatment group received conventional treatment. In addition to conventional treatment, the ultra-early intervention group was given ultra-early intervention . When two groups of children's corrected gestational age at 40 weeks, 42 weeks and 44 weeks, they need to be tested for NBNA neonatal neurobehavioral testing, Alberta Infant Exercise Scale (AIMS) assessment and general exercise quality assessment (GMs ). Results: When the child's corrected gestational age is 40 weeks, there is no significant difference in the scores of NBNA and AIMS between the ultra-early intervention group and the conventional treatment group; When the child's corrected gestational age is 42 weeks, the NBNA and AIMS scores of the ultra-early intervention group are higher than those of the conventional treatment group, but there is no statistical significance; When the child's corrected gestational age is 44 weeks, the ultra-early intervention group had higher NBNA and AIMS scores than the conventional treatment group, which was statistically significant (P<0. 05). Conclusion: After ultra-early intervention, the development level of gross motor in the ultra-early intervention group was significantly higher than that in the conventional treatment group. Ultra early intervention has obvious effect on the improvement of gross motor function in neonates with hypoglycemic brain injury
Correlation Analysis of Patients with Adverse Reactions Caused by Postoperative Morphine Analgesia
Get PDFIn the current medical field of clinical surgery, we often have to contact a large number of patients with severe fractures caused by serious accidental injuries. Generally, these trauma patients often need to be treated by repair surgery. Postoperative patients usually have a certain degree of local pain. In order to alleviate the physiological pain of postoperative patients, And can prevent the braking caused by the aggravation of local pain of the injured patients. The use of analgesic pump for postoperative analgesia has become a common method after surgery and has been widely used in clinic. Good postoperative analgesia can inhibit the body's stress response and is conducive to restoring the coordination and stability of local breathing and circulation of the patients after operation, Reduce the local pain symptoms of some patients and effectively reduce their postoperative related complications, and indirectly promote the recovery of patients with pain. For the application of analgesic pump for pain relief, there are often a variety of auxiliary ways and preparation methods of analgesic drugs such as arteriovenous and epidural circulation, which should be selected and configured according to the physical conditions and medication conditions of patients with pain, such as ns100ml Morphine 5mg, bupivacaine 75mg, etc., of which morphine is often used as a common drug component for pain relief, but some special patients often have a series of dependent reactions after using morphine for pain relief. In view of this situation, combined with the physical conditions and adverse reactions of some special patients, this paper analyzes the possible adverse effects on patients with special constitution when using morphine for pain relief after clinical operation and relevant research
Research Progress of Breast Tissue Marker Clips and Their Application in Neoadjuvant Therapy for Breast Cancer
Get PDFCurrently, breast cancer being of rapidly increasing incidence rates and as the most commonly diagnosed malignant tumor in breast surgery, has attracted much attention. Neoadjuvant therapy (NAT) has been proved to be beneficial for reducing tumor size and breast-conserving surgery. As a new type of metal localization marker, breast tissue marker clips can be used to precisely locate tumor tissue and improve cure rates. This review focuses on the marker clips and their significance in the diagnosis and treatment of neoadjuvant therapy for breast cancer, hoping to provide more clinical bases for research and promote this technology
The Development Prospect of Chinese Rehabilitation Specialist Nurses under the Background of Aging
Get PDFObjective: To explore the correlation between the supply-demand contradiction and development of rehabilitation nursing talents in China through the analysis of China's aging population. It provides ideas for the increasingly professional and regularization of rehabilitation nursing in China, and provides evidence-based suggestions for the employment of rehabilitation specialist nurses. Design: Review Article. Methods: Literature review. Finding: Due to the traditional concept of Chinese society and the low recognition of rehabilitation specialist nurses, the training institutions for rehabilitation specialist nurses are not perfect, and the education level of rehabilitation specialist nurses is uneven, making it difficult to meet the needs of Chinese rehabilitation nurses. Conclusion: Call on more nursing talents to participate in the construction of rehabilitation nursing in China.Explore the prospects for the development of rehabilitation specialist nurses around the world, take China as an example, and provide evidence-based advice for the employment of rehabilitation specialist nurses
Clinical Research Review of Acupuncture for Laryngopharyngeal Reflux Disease
Get PDFIn recent years, laryngopharyngeal reflux disease has attracted the attention of acupuncture clinicians. This article summarizes the acupuncture treatments (simple acupuncture, acupuncture combined with western medicine, acupoint application combined with Chinese medicine) and the corresponding treatment effects in the past 5 years. The current research has proved the effectiveness of acupuncture and moxibustion for laryngopharyngeal reflux disease, and provides methods and ideas for clinical treatment of laryngopharyngeal reflux disease
Using Chimeric Antigen Receptor Modified T-Cell to Treat B-Cell Leukemias
Get PDFLeukemias are cancers that happened in the blood of organisms, which affect the immune system’s T cells and B cells. Therefore, investigating studies to cure this disease are crucial. Several researchers demonstrated the use of modified receptors of T cells to fight leukemia. CTL019 (tisagenlecleucel) is a type of therapy that transplants the CD19 receptors into T cells to help them recognize the CD19+ B cells. They are used to detect and kill the cancerous B cell leukemia cells.  The chimeric antigen receptor-modified T-cell (CAR-T)  is a method that extracts the blood cells from the patients to cultivate the CD19 receptors. Finally, the blood would be injected back into the patients. Even though this method effectively kills CD19+ B-cells, it may have some side effects, such as the quick release of cytokines that can cause high systemic effects. With these side effects, scientists should investigate a better way to reduce the side effects in the future
Pharmacological Study of Phenolic Components in Parkinson's Disease
Get PDFIn this study, cell experiments were conducted to investigate the effects of extracts on cell viability and apoptosis of Parkinson model in vitro, as well as the expression of cysteine protease-3 (Caspase-3) and B lymphocytoma-2-associated X protein (BAX). The results showed that extract of phenols could improve the loss of cell viability and apoptosis induced by MPP+, and inhibit the enhanced expression of Bax and Caspase-3 by MPP+. The potential targets and signaling pathways of phenols in the treatment of Parkinson's disease were predicted by network pharmacology
The Relationship between Core Knowledge of Tuberculosis and Mental Health: A Cross-Sectional Study Among University Students in Tibet
Get PDFThe relationship between core knowledge of TB and mental health among students in a university was investigated. The results showed that the overall knowledge rate of core knowledge of tuberculosis was 71%. The main effects of coping style and standard level on mental health, anxiety, and self-denial were significant. In terms of mental health, the results had borderline significant, and the positive attitude of the "not up to standard" participants was conducive to a good mental state. This suggests that schools should not only strengthen the education of students on TB prevention and control but also cultivate positive attitudes among students
Application Comparison of Contrast-Enhanced Ultrasound-Guided Microwave Ablation and Traditional Surgery for Benign Breast Nodules
Get PDFObjective:Â To analyze the therapeutic effect of contrast-enhanced ultrasound-guided microwave ablation and traditional surgery in the treatment of benign breast nodules. Methods: The research subjects included in this study were 68 patients with benign breast nodules admitted to our hospital from January 2020 to January 2021. They were divided into control group and experimental group by random number table method. The control group received traditional surgical treatment (34 cases), and the experimental group received contrast-enhanced ultrasound-guided microwave ablation (34 cases). The treatment effects of the two groups were compared. Results:Â There was no significant difference in operation time between the two groups, which did not meet statistical significance (P>0.05). Intraoperative blood loss, incision healing time and pain score were lower in the experimental group than in the experimental group (P<0.05). There were significant differences in postoperative hematoma, scar formation rate and lesion residual rate between the two groups, among which the experimental group was lower (P<0.05). Conclusion:Â Contrast-enhanced ultrasound-guided microwave ablation and traditional surgery are used in the treatment of benign breast nodules. The former is better than the latter. This treatment method can be promoted
Clinical Study of Endocrine Hormone Combined with Trastuzumab in Maintenance Treatment of HR and HER-2 Positive Advanced Breast Cancer
Get PDFObjective:Â To analyze the clinical effect of endocrine hormone combined with trastuzumab in maintenance therapy of HR (hormone receptor) and HER-2 (human epidermal growth factor receptor) positive advanced breast cancer. Methods:Â A total of 80 patients with HR and HER-2 positive advanced breast cancer admitted to our hospital from January 2020 to December 2022 were selected, and the 80 patients were divided into 2 groups by random number table method, the control group (N= 40) The patients in the observation group (N=40) were treated with trastuzumab, and the patients in the observation group (N=40) were treated with endocrine hormones and trastuzumab for maintenance. The therapeutic effects of the two groups were compared. Results:Â The two groups of patients had similar serum CD8+, CD4+, CD3+ before treatment and CD8+ after treatment (P>0.05). After treatment, the CD4+ and CD3+ in the observation group were higher than those in the control group (P<0.05). The total effective rate of the observation group was significantly higher than that of the control group. It was higher in the control group (P<0.05); the incidence of adverse reactions in the observation group was lower than that in the control group (P<0.05). Conclusion:Â Endocrine hormone combined with trastuzumab maintenance therapy for HR and HER-2 positive advanced breast cancer has significant clinical effect, can effectively improve the immune indexes of patients, and has less adverse reactions, which is worthy of clinical application