Advanced Emergency Medicine (E-Journal)
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Domain Ontology Construction in the Glioma
Get PDFObjective To construct a domain ontology for glioma, and to achieve knowledge sharing and reasoning in the field of glioma through reuse and sharing of knowledge. Methods A domain ontology for glioma was constructed using the Ontology Web Language as the description language and a seven-step approach with the help of the ontology construction tool Protégé 5.5.0 as a knowledge source. Results A more comprehensive knowledge system related to glioma was presented, with 35 classes, 85 instances, 8 object properties and 5 data properties constructed. Conclusion By integrating the glioma knowledge and establishing the corresponding domain ontology, it provides knowledge support and reasoning basis for sharing, reusing and building the knowledge base of glioma knowledge
Research Progress on Integrated Traditional Chinese and Western Medicine in the Treatment of Post-Cholecystectomy Syndrome
Get PDFLaparoscopic cholecystectomy (LC) is a highly accepted treatment at this stage, with the increasing incidence of biliary tract disease and the development of endoscopic technique in recent years However, some patients after cholecystectomy still have symptoms similar to preoperative symptoms, such as abdominal pain, diarrhea, indigestion and so on. This series of syndromes has become a common clinical problem at present.This article reviews the research progress of etiology, pathogenesis, diagnosis and treatment of post-cholecystectomy syndrome by reading related literatures
Predictive Effect of Pelvic Floor Ultrasound Parameters on Stress Urinary Incontinence After Cesarean Section
Get PDFObjective: To explore the predictive effect of pelvic floor ultrasound parameters on stress urinary incontinence after cesarean section. Methods: The pregnant women who underwent cesarean section in our hospital from April 2021 to April 2022 were selected as the study subjects. Fifty pregnant women with SUI within 6 months after delivery were selected as the study subjects in the experimental group. However, 50 patients who underwent cesarean section for 6 months after delivery and did not initially choose SUI were selected as the control group study subjects. The experimental content was to observe the probability of PUA, BNS, LHA, BND, URA in two groups of pregnant women under resting state. To analyze the predictive effect of ultrasound parameters on SUI after cesarean section. Results: There was no significant difference in PUA and LHA between the two groups of pregnant women at rest (P>0.05); The BNS in the resting state and the maximum Valsalva state in the experimental group were significantly lower than those in the control group. Through comprehensive collection of six data, it is possible to summarize the predictive role of pelvic floor ultrasound parameters for stress urinary incontinence after cesarean section. The data obtained by the combined diagnosis method is significantly higher than the single prediction data. Conclusion: Basin ultrasound parameters have a high predictive value for postpartum SUI after cesarean section, and combining ultrasound parameters can improve the diagnostic efficacy of postpartum SUI after cesarean section
Pelvic Floor Ultrasound Evaluation of the Impact of Delivery Times and Delivery Methods on the Anterior Pelvic Cavity
Get PDFObjective: To evaluate the impact of delivery frequency and delivery method on the anterior pelvic cavity using pelvic floor ultrasound. Method: 200 women who gave birth in our hospital from January 2019 to January 2022 were selected as the research subjects, including 100 first-time vaginal delivery women, 50 second-time vaginal delivery women, and 50 cesarean section women each. The control group consisted of 100 women who underwent a 15 day follow-up examination after the first artificial abortion surgery in our hospital during the same period. The patients were divided into a control group, a first-time delivery group, a second-time delivery group, and a cesarean section group. Observing the changes in the anterior pelvic structure during resting state and maximum Valsalva movement through perineal ultrasound examination. Result: The distance from the bladder neck to the reference line in the resting state was significantly different between the control group, cesarean section group, first vaginal delivery group, and second vaginal delivery group (P<0.05); During the maximum Valsalva maneuver, the detection rate of bladder neck mobility, urethral rotation angle, posterior angle of bladder, and funneling of internal urethral orifice, the second vaginal delivery group, the first vaginal delivery group>the cesarean section group>the control group, and the difference between each group was statistically significant (P<0.05). During the maximum Valsalva maneuver in the first and second vaginal delivery groups, the lowest point of the bladder was located below the reference line, and there was no statistically significant difference between the two groups (P>0.05); During the maximum Valsalva maneuver in the cesarean section group and control group, the lowest point of the bladder was located on the reference line, and there was no statistically significant difference between the two groups (P>0.05); The difference between the vaginal delivery group and the cesarean section and control group was statistically significant (P<0.05). Conclusion: Different birth times and delivery methods have varying degrees of impact on the anterior pelvic cavity of women. Pelvic floor ultrasound can early evaluate these structural changes and provide reliable basis for the screening and diagnosis of pelvic floor dysfunction disease (PFD)
Summary of Experimental Studies on the Effects of RDPR on the Cardiovascular System
Get PDFAs a special diet, it has a relatively large number of study compared with other health foods. The scope includes basic and animal experiments, studies in healthy populations, people with cardiovascular risk factors, and patients with vascular diseases. Related studies show that erythrospinal peptide has certain effects of antiplatelet aggregation, dissolving thrombosis in vitro, lowering blood pressure, lowering blood lipid, and enhancing immunity
The Follow-up Report of MRI After Transforaminal Endoscopic Surgery of Lumbar Disc Herniation with Spinal Stenosis
Get PDFObjective: To observe the imaging changes of MRI in the responsible disc area after modifed TESSYS foraminal scopy in pa-tients with lumbar disc herniation (LDH), and to explore the postoperative repair time of the responsible disc area, so as to provide imaging reference for the rehabilitation plan of the patients. Materials: To investigate the VAS score and MRI imaging of patients with lumbar disc herniation and spinal stenosis after transforaminal endoscopic surgery, which to lay the foundation for the rehabilitation plan. Methods: Ten patients with lumbar disc herniation (L4/5, L5/S1) with spinal stenosis were collected and followed up by MRI and the VAS score on 1 week, 1 month, 4 months and 6 months after transforaminal endoscopic surgery. Results: The VAS score were signifcantly lower than those before operation (P 0.05) on 1 month and 6 months after operation. The high signal could be seen around the intervertebral foramen and nerve roots on the operation site on 1 week, 1 month and 4 months after operation Which disappeared at 6 months after operation. Con-clusion: The symptoms of low back and leg pain in patients with lumbar disc herniation and spinal canal stenosis disappeared after 1 month, while the infammatory reaction symptoms of intervertebral foramen and nerve root were disappeared on 6 months
Analysis of Abnormal Gait in the Diagnosis of Early Neurodegenerative Diseases: A Review
Get PDFEarly detection of neurodegenerative diseases can increase the possibility to access to treatment, and assist in advance care plan-ning. At present, most of the gait researches focus on the design and application of recognition tools for disease diagnosis, such as recording the walking and movement status through wearable sensor devices, while, relatively less non-contact machine vision is used to measure gait. The non-contact gait detection method is characterized by the advantages, including the absence of human cooperation, non-invasive nature and so on, which is also suitable for long-distance perception. In this paper, we focused on some non-contact analysis methods for abnormal gait, and it is hoped that it can provide guidance for the diagnosis of neurodegenerative diseases
Indole-Based Compounds as Promising Inhibitors of SARS-CoV-2
Get PDFThis review focused on the recent development of indole-based compounds as anti- SARS-CoV-2 agents with focus on the following objectives: 1) present the design strategy of indole-based compounds as promising inhibitors; 2) focus on recent developments of indole-based compounds and their anti-severe acute respiratory syndrome coronavirus 2 and anti-severe acute respiratory syndrome coronavirus activities; 3) summarize molecular docking and the structure–activity relationship, in hopes to inspire the development of new and more creative approaches; and 4) offer perspectives on how indole scaffolds might be exploited in the future
Research Progress of Abnormal Expression of LKB1/STK111 in Non-Small Cell Lung Cancer
Get PDFNon small cell lung cancer (NSCLC) is a kind of malignant tumor originated from bronchial mucosa, bronchial glands and alveolar epithelium. It has become the main cause of death of malignant tumors in our population. STK11 is a common tumor suppressor gene, its encoded protein liver kinase B1 (LKB1) is an essential serine / threonine protein kinase. LKB1/STK111 inhibits the occurrence and development of tumors through a variety of mechanisms and plays a key regulatory role in malignant tumors. The increased risk of cancer development is also associated with the absence of STK11. More and more studies have found that the abnormal expression of LKB1/STK111 will affect the occurrence and development of lung cancer, especially in NSCLC. This paper reviews the tumor suppressive mechanism of LKB1/STK111 in the occurrence and development of NSCLC, its relationship with NSCLC, and the prognosis and treatment
Clinical Observation of External Fixation Stent Combined with Limited Open Reduction and Kirschner Wire Internal Fixation for Comminuted Distal Radius Fracture
Get PDFTo investigate the clinical effect of external fixation stent combined with limited open reduction and Kirschner wire internal fixation in the treatment of comminuted distal radius fracture. Methods: A total of 40 patients with comminuted distal radius fractures from January 2018 to December 2021 were selected, including 15 males and 25 females. Age 35-74 years old; AO type: C2 type 26 cases, C3 type 14 cases. External fixation stent combined with limited open reduction and internal fixation with Kirschner wire were used for the surgery. Wrist function was evaluated by Dienst score at the last follow-up. Results: In this study, all patients were followed up for 6-12 months after surgery, with an average of 8.5 months. Bone union was achieved in all patients. Complications: 1 case of nail tract infection, 2 cases of Kirschner wire withdrawal, 1 case of traumatic arthritis; According to Dienst score of wrist joint function, 25 cases were excellent, 12 cases were good, and 3 cases were fair. The excellent and good rate of wrist joint function was 92.5% (37/40). Conclusions: External fixation stent combined with limited open reduction and Kirschner wire internal fixation for the treatment of comminted distal radius fracture can effectively fix, avoid the second incision and removal operation, can be performed according to the early stage of functional exercise, postoperative functional recovery of the wrist, providing an effective treatment method for the clinical treatment of this kind of fracture