Journal of Ayurveda and Integrated Medical Sciences (JAIMS)
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A comparative clinical study on the role of Agnimantha Shilajit Yoga and Bilvadi Yoga in the management of Sthaulya w.s.r. to Overweight and Obesity
No full textObesity (Sthaulya) is a chronic lifestyle disorder described in Ayurveda as a condition associated with Medo Dhatu Vruddhi and Srotorodha. This randomized clinical trial aimed to evaluate and compare the efficacy of Agnimantha Shilajit Yoga (AS) and Bilvadi Yoga (BY) in the management of obesity. Sixty clinically diagnosed patients were randomly allocated into two groups: Group A received AS (0.5g twice daily), and Group B received BY (5g twice daily with 10 mL honey). Both groups were assessed on subjective and objective parameters over the treatment period. The study population was predominantly male (53.34%), aged between 36-47 years (51.70%), mostly married (85%), with a preference for spicy food (50%), Krura Koṣta (63.35%), Viṣamagni (88.30%), and a mixed diet (95%). Group A showed statistically significant improvement in subjective symptoms such as reduction in pendulous body movements, heaviness, excessive perspiration, thirst, and hunger (p < 0.001). Objective parameters such as body mass index - BMI (Decreased from 3.60 to 2.00 (p < 0.001), indicating a marked reduction in weight status), lipid profile (Mean value of total cholesterol reduced from 244.68 to 189.04), liver enzymes (AST, ALT, ALP), creatinine levels, waist and hip circumferences also improved significantly (p < 0.001). Group B demonstrated notable reductions in localized adiposity, including mean value of thigh circumference (from 57.56 to 54.50 cm) and mean value of arm circumference (from 34.86 to 31.46 cm) (p < 0.001), though improvements in other parameters were less pronounced compared to Group A. Intergroup comparison revealed that AS was significantly more effective in most essential obesity-related parameters, while BY was more effective in targeted fat reduction. Both formulations were found to be effective in managing obesity, but AS demonstrated a broader and more comprehensive efficacy in the Ayurvedic management of Sthaulya
Management of Post Breast Conservative Surgery in Stana Arbuda w.s.r. to Breast Carcinoma - An Ayurvedic Perspective
No full textBreast cancer is the commonest malignancy among women globally. From being fourth in the list of most common cancers in India during the 1990s, it has now become the first.[1] Epidemiological studies have shown that the global burden of BC is expected to cross almost 2 million by the year 2030.[2] From an Ayurvedic view, Arbuda (cancer) is caused by the vitiation of Tridosha, Dhatu (Rakta, Mamsa, Meda), Agni, and Mala. When localized in the breast, it is termed as Stana Arbuda. Given its increasing global burden and impact on women’s health, a comprehensive and integrative treatment approach is essential. Ayurveda offers a holistic perspective, aiming to improve quality of life in affected individuals. A 50-year-old female post conservative breast surgery, with a score of BIRADS-5 and advised for radiation and chemotherapy, presented with Right breast surgical scar pain with restricted movement of right shoulder and generalised weakness. She was managed with Shamanaushadhi’s and Rasayana therapy. This case highlights the role of Ayurvedic interventions in supporting recovery, minimizing side effects, and enhancing immunity in post-cancer patients. Integrative care can help maintain overall health and potentially reduce the risk of recurrence
Restoration of Menses in Artavakshaya (Delayed Menstruation) Through Ayurvedic Care: A Case Report on an Adolescent Female
No full textBackground: Menstrual disorders are among the most common gynecological concerns in India, with oligomenorrhea (delayed menstruation) affecting approximately 14-25% of adolescent and reproductive-age women. Contributing factors include psychological stress, dietary imbalances, hormonal dysregulation, and sedentary lifestyles. From an Ayurvedic standpoint, this condition aligns with Artavakshaya, Nashtartava, or Artava Dushti, involving vitiation of Vata and Kapha Doshas, impaired Agni (digestive/metabolic fire), and blockage in Artavavaha Srotas (channels of menstrual flow).
Case Presentation: This report presents the case of a young female with a history of irregular menstrual cycles, accompanied by dysmenorrhea, ultrasound-confirmed bilateral cystic ovaries, and hormonal imbalance. She was treated using a classical Ayurvedic protocol including internal medications (Varanadi Kashayam, Rajapravartini Vati, Aruna Syrup, Kumaryasava, and Kanchanara Guggulu) and a Kshara Vasti course. The intervention led to the regularization of her cycles and symptomatic relief without the use of hormonal therapy.
Conclusion: This case underscores the utility of a holistic Ayurvedic approach, incorporating classical formulations, detoxification therapies, and lifestyle correction, for effective and sustainable management of delayed menstruation
Promoting Musculoskeletal Health in the Elderly Through Gut Microbiome Support with special reference to Ayurvedic Dietetics - A Review
No full textAging brings a variety of mental and physical challenges, particularly musculoskeletal diseases, which significantly impact the quality of life in elderly individuals. Variations in gut microbiome composition are increasingly recognized as contributing to musculoskeletal disorders such as sarcopenia, tendinopathy, and arthritis. This review examines the relationship between gut dysbiosis and musculoskeletal disorders in the elderly and explores the potential role of Ayurvedic dietary practices in maintaining gut health, preventing disease progression, and promoting healthy aging. The scientific literature on the relationship between gut microbiome variations and musculoskeletal diseases in elderly populations is reviewed. Ayurvedic principles, particularly those focusing on personalized nutrition and Dosha balance, are analyzed for their potential to modulate the gut microbiome. Gut dysbiosis in elderly individuals contributes to musculoskeletal disorders, potentially through impaired nutrient metabolism. Ayurvedic dietary practices, particularly those aligned with Ashtahara Vidhiviseshayatana (the eight-fold dietetic rules), provide a holistic approach to preserving gut health, mitigating disease risks, and promoting musculoskeletal health. The review highlights the importance of gut health in musculoskeletal health during aging. Ayurvedic dietary practices offer a promising strategy for maintaining gut health and preventing musculoskeletal disorders in the elderly. Further studies are necessary to validate these traditional approaches and integrate them with modern medical practices
Analgesic Evaluation of Pancha Shirishanama Agad: A Pharmacological Study Using Hot Plate Model in Mice
No full textIntroduction: Pain resulting from insect bites is primarily nociceptive, triggered by tissue injury and bioactive venom components such as histamine, serotonin, kinins, and proteolytic enzymes that activate inflammatory and nociceptive pathways, leading to peripheral and central sensitization. Such envenomation in Ayurveda are described as Keeta Visha, characterized by Vedana (pain), Shopha (swelling), Kandu (itching), Daha (burning), and Jwara (fever). To treat such conditions, Modern pharmacological treatments like opioids and non-steroidal anti-inflammatory drugs (NSAIDs) are widely used, but they often come with side effects and the threat of dependency. This has high-lightened a growing interest in natural and herbal alternatives that provide a safer and more comprehensive approach to healing. Pancha Shirishanama Agad, a classical anti-toxic formulation, is traditionally used to alleviate these symptoms through its detoxifying (Vishaghna), analgesic (Vedana Sthapana), and anti-inflammatory (Shothaghna) properties.
Materials and Methods: Eighteen Swiss albino mice were divided into three groups (n=6 each): control (distilled water 5ml/kg), test (Pancha Shirishanama Agad 9.86 ml/kg), and standard (diclofenac sodium 1% solution of 10 mg/kg). Analgesic activity was evaluated using hot plate model at 30-, 60-, and 90-minutes post-administration. Data were statistically analyzed using one-way ANOVA followed by Dunnett’s test.
Results: The test drug demonstrated a significant increase in latency period at 30 minutes (24.72 ± 10.45 sec) compared with control (7.18 ± 0.32 sec) (p=0.0052), indicating rapid-onset analgesia. No statistically significant differences were observed at 60 and 90 minutes in comparison to the control group.
Conclusion: Pancha Shirishanama Agad exhibits a fast-acting analgesic effect, likely mediated through both peripheral and central mechanisms. The findings support its traditional use in managing acute inflammatory pain and swelling associated with insect toxins
Retrospective Evaluation of Swayampurna Upchar Therapy for Type 2 Diabetes Mellitus: Impact on Clinical Outcomes, Symptom Relief, and Quality of Life
No full textIntroduction: Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder requiring lifelong management. While conventional care focuses on glycemic control, alternative therapies are gaining interest for improving symptoms, psychological well-being, and quality of life. This study evaluates the effectiveness of Swayampurna Upchar Therapy a non-invasive, energy-based Ayurvedic modality in individuals with T2DM, with emphasis on symptomatic and psychosocial outcomes.
Materials and Methods: A total of 150 de-identified clinical records of individuals with confirmed T2DM who received Swayampurna Upchar Therapy at Niraamay Wellness Centre were retrospectively reviewed in this observational study. Patient-reported outcomes included diabetes symptom burden, emotional well-being, quality of life, and medication usage, complemented by laboratory parameters related to glycemic control. Data were collected at baseline and at the end of the study period, and pre–post changes were analyzed using the Wilcoxon signed-rank test.
Results: Significant improvements were observed post-intervention in diabetes-related symptoms, emotional well-being, and glycemic markers (all p < 0.005). Diabetic classifications declined across HbA1c (n=93 to n=39), Fasting BSL (n=83 to n=28), and Postprandial BSL (n=59 to n=8), with parallel increases in pre-diabetic and normoglycemic categories. One-third of participants reduced or discontinued diabetic medications.
Discussion: This study highlights the potential of Swayampurna Upchar as a non-pharmacological intervention for T2DM, with measurable benefits in both physiological and psychological health. Its integrative, patient-centered approach aligns with the growing interest in holistic diabetes care. These findings, while encouraging, warrant confirmation through well-designed prospective studies
Nayanasukhavarti Anjana in the management of Timira (Myopic Astigmatism): A Case Study
No full textIntroduction: Myopic astigmatism is a refractive error that combines myopia and astigmatism. Nethra is considered the best among the Pancha Jnanendriyas. In Ayurveda, there are many Shamanaaushadi and Kriyakalpas mentioned for Netra Rogas. Netra Kriyakalpas include Seka, Ashchothana, Anjana, Pindi, Vidalaka, Tarpana & Putapaka. Anjana is the application of medicinal paste over the eyes.
Materials & Methods: A fully conscious female patient aged 26 years visited Shalakya Tantra OPD, Alvas Ayurveda Medical College, Moodbidre, with complaints of defective distant vision in both eyes for 7 years. The patient was managed with Nayana Sukha Varti Anjana for 1 month, and follow-up was taken after 1 month.
Results: Subject got significant improvement in visual acuity in both eyes.
Conclusion: This case highlights the potential of Ayurvedic ophthalmic interventions, specifically Anjana Karma with Nayana Sukha Varti, as supportive therapy in managing myopic astigmatis
Role of Rasa Panchaka in Predicting Drug Action - A Review Based on Medohara Dravyas
No full textThe pharmacodynamic principles of Ayurveda are fundamentally rooted in the doctrine of Rasa Panchaka, which provides a predictive and rational framework for understanding the mode of action of Dravyas (substances). Rasa Panchaka—comprising Rasa (taste), Guna (qualities), Virya (potency), Vipaka (post-digestive effect), and Prabhava (specific action)—collectively governs a drug’s therapeutic impact on Dosha, Dhatu, and Mala. These five parameters together explain both general and specific pharmacological responses observed in Ayurvedic therapeutics. Among various categories of drugs, Medohara Dravyas hold significant clinical importance in managing Sthoulya (obesity) and other Medoroga (metabolic disorders) characterized by Kapha-Meda aggravation. Classical Ayurvedic texts describe that Medohara Dravyas predominantly possess Katu (pungent), Tikta (bitter), and Kashaya (astringent) Rasa; Laghu (light) and Ruksha (dry) Guna; Ushna Virya (hot potency); and Katu Vipaka (pungent post-digestive effect), which collectively promote Agni Deepana (enhancement of metabolism), Ama Pachana (detoxification), and Lekhana Karma (scraping of excess fat).This review critically examines the predictive potential of Rasa Panchaka in determining and explaining the pharmacological actions of selected Medohara Dravyas—namely Triphala, Guggulu, Musta, Haridra, and Vrikshamla. Correlating Ayurvedic pharmacodynamic principles with contemporary biochemical and pharmacological evidence, it rationalizes their Medohara (lipid-reducing), Shothahara (anti-inflammatory), antioxidant, and hypolipidemic properties. Modern research has validated these classical predictions by demonstrating mechanisms such as improved lipid metabolism, antioxidant enzyme modulation, and inhibition of adipogenesis. The paper underscores the scientific relevance of Ayurvedic drug theory and establishes Rasa Panchaka as a reliable predictive tool for understanding and forecasting drug action within evidence-based herbal pharmacology. Integrating these ancient pharmacodynamic concepts with modern biochemical insights can contribute significantly to rational Ayurvedic drug development and integrative pharmacological research
A Randomized Controlled Trial Protocol for the Immediate Effect of Chandra Namaskar on Cardiovascular Autonomic Function among Healthy Individuals
No full textBackground: Chandra Namaskar, a dynamic yoga practice incorporating unique postures and breathing patterns, is believed to improve flexibility, cognition, and concentration, and enhance sympathovagal balance. However, its immediate effects on cardiovascular autonomic function remain underexplored. This study aims to investigate the acute impact of Chandra Namaskar on heart rate variability (HRV), critical flicker fusion frequency (CFFF), and reaction time among healthy individuals.
Methods: This randomized controlled trial will involve 60 healthy participants aged 18-25 years. Participants will be randomly allocated to either the Chandra Namaskar intervention group or the supine relaxation control group. HRV will be assessed at baseline, during, and immediately after the intervention using a 16-channel polygraph. CFFF and reaction time will be evaluated at baseline and post-intervention. Statistical analysis will be performed to compare the outcomes between the two groups.
Discussion: This study protocol aims to provide high-quality clinical evidence on the potential benefits of Chandra Namaskar in improving cardiovascular autonomic function and cognitive performance. The findings may contribute to the development of effective strategies for enhancing overall health and well-being through this accessible yoga practice
Saribaadi Agada in Lutha Visha Chikitsa - A Review Article
No full textAgadatantra is one of the eight specialized branches of Ayurveda that deals with the study and management of various poisons originating from animals, plants, minerals and artificial sources, along with their modes of action, signs and symptoms of poisoning and the measures for their prevention and treatment. In Ayurveda, Visha is broadly classified as Sthavara, Jangama and Kritrima. Lutha Visha comes under Jangama Visha. Timely and appropriate management of Lutha Visha is very important because the toxins present in the venom can rapidly aggravate Doshas and produce severe local as well as systemic effects. Saribaadi Agada is a formulation mentioned in Kriyakaumudi, Keetadivishaprakarana, in the context of Lutha Visha. The formulation comprises ten ingredients and may be used externally in the form of Taila. This article attempts to elucidate the possible mechanism of action of Saribaadi Agada through an analysis of its pharmacological properties