Journal of Ayurveda and Integrated Medical Sciences (JAIMS)
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A Case Report of Kaphaja Granthi w.s.r. to Trichilemmal Cyst
Get PDFTrichilemmal cysts are firm, slow-growing lumps that develop when a hair follicle becomes blocked by keratin and dead skin cells. They are typically asymptomatic unless they calcify or rupture. The cysts have smooth, spherical nodules with a solid feel and good movement. The other less common areas include the face, trunk and extremities. Lesions are uncommon in the palms, genitalia, axilla and groin. It affects less than 10% of the population. Trichilemmal cyst are also called as Pilar cyst which may be inherited as an autosomal dominant trait
Effect of Viruddha Ahara on the Gut Microbiota - A Review
Get PDFThe Gut microbiota, which constitutes the various bacterial flora in our body, plays a vital role in maintaining Homeostasis, Immune balance, Emotional and mental stability and overall health. Disruption of this complex ecosystem is known as “Dysbiosis” which has been implicated in a range of disorders like inflammatory bowel disease, obesity, cardiovascular diseases etc. Among the various factors influencing this, the role of Viruddha Ahara remains to be established. In Ayurvedic literature, Viruddha Ahara refers to incompatible combinations of foods that disturb the physiological equilibrium. This study aims to establish that Viruddha Ahara contributes to dysbiosis through a review of published studies on Gut Microbiota and the effects of dietary behaviour on them. The findings suggest that Viruddha Ahara may act as a factor in gut balance, supporting the integration of Ayurvedic principles in modern gut-based health
Neutraceutical Potential of Some Kanda Shak (Tuberous vegetables): A Review
Get PDFAhar is regarded as Mahabheshaja in Ayurveda. It refers to any substance that is chewed and ingested for nutritional and energy purposes. Shak (vegetables) are included in the diet as essential components by ancient sages, contemporary ayurvedic and modern medical scientist / nutritionists. In Charak Samhita and Ashtanga Hridaya, tubers are mentioned under Ahar Varga and Acharya Sushrut especially explained it in Kanda Varga (Group of tuberous vegetables). Tuberous vegetables boast several noteworthy properties that contribute to their nutritional value as they are rich in all essential dietary components like carbohydrates, proteins, fats, vitamins and dietary fibres. In addition, tubers also contain vitamins, minerals, trace elements and biologically active molecules that function as antioxidants, phytoestrogens, and anti-inflammatory agents. Consumption of these tubers may play a role in preventing diseases in which free radicles are involved such as cancer, ageing, cardiovascular diseases. Present review is an attempt to explore nutraceutical potential of Kanda Shak described in Brihattrayi and a comparative analysis with their nutraceutical composition explored by modern analytical studies
A Prospective, Open-label Non-Randomized Clinical Trial to evaluate the Safety and Efficacy of Takzema Tablet & Ointment in Treatment of Eczema
Get PDFBackground: Eczema, or atopic dermatitis (AD), is a chronic inflammatory skin disorder characterized by pruritus, erythema, and xerosis, affecting upto 20% of individuals and significantly impacting quality of life. Conventional treatments include topical corticosteroids, calcineurin inhibitors, PDE4 inhibitors, phototherapy, and systemic immunosuppressants, though long-term use may have adverse effects. Advances in translational research have led to targeted small molecules and biologic therapies for moderate-to-severe cases.[1] Takzema Tablet & Ointment, are polyherbal formulations manufactured by Charak Pharma Pvt. Ltd., and were evaluated for its efficacy and safety in patients with Eczema. A total of 300 patients were included in the study to assess the impact of this treatment approach.
Materials and Methods: This phase 3, non-randomized, prospective, open-label, multi-centric clinical trial aimed to evaluate the clinical efficacy and safety of Takzema Tablet & Ointment in managing patients aged 18–60 years diagnosed with Eczema.
Observation: Over a two-month period, Takzema demonstrated significant improvement across multiple clinical parameters. Erythema scores declined by 48.4% (p < 0.001), with the greatest reduction observed in the head/neck region. Oedema/papulation severity decreased by 63.9% (p = 0.002), with the highest improvement in the trunk (68.4%). Lichenification showed an overall reduction of 47.06% (p = 0.001), with the most significant improvement in the head/neck and upper extremities. The affected area scores also declined by 51.39% (p = 0.002), demonstrating consistent regional improvements.
Result: Takzema Tablets & Ointment demonstrated significant improvements in eczema symptoms after 2 months of treatment, including reductions in erythema, oedema/papulation, lichenification & total area lesions. The results highlight that Takzema tablets & ointment are clinically effective in managing eczema
An Ayurvedic intervention in management of Adenomyosis (Bulky Uterus) - A Case Report
Get PDFAdenomyosis, as described, is a condition where the endometrial tissue exists and grows abnormally into the uterine muscle wall, leading to thickened myometrium, heavy menstrual bleeding and painful menstruation (dysmenorrhea). While modern medicine addresses it through hormonal therapies, surgical options or other interventions, Ayurvedic understanding focuses on symptom-based correlations. In Ayurveda, the symptoms mentioned, such as: Teevra Vedana (severe pain) - Reflects the intense discomfort during menstruation, Shyava Arun Varna Artava (dusky/reddish-brown menstrual flow) - Indicates abnormalities in the menstrual blood and, Kati Vedana (lower back pain) - Common in gynecological conditions. These align closely with Vataj Asrigdara, a condition characterized by Vata Dosha vitiation affecting the menstrual flow, leading to irregularities and pain
A Prospective, Open-label Non-Randomized Clinical Trial to evaluate the Safety and Efficacy of Calcury Tablets in Treatment of Renal calculi
Get PDFBackground: Renal calculi, commonly referred to as kidney stones, are a prevalent urological condition characterized by the formation of solid mineral and salt deposits within the urinary tract. The management of renal stones involves a multifaceted approach, including hydration, dietary modifications, pain management, pharmacological interventions, and, in some cases, surgical procedures such as lithotripsy or ureteroscopy. Preventive strategies focus on addressing the underlying metabolic causes and promoting adequate hydration to minimize recurrence.
Materials and Methods: This non-randomized, prospective, open-label clinical trial involving 50 patients aimed to evaluate the clinical efficacy and safety of Calcury Tablets in managing renal calculi in patients aged 20–65 years, a demographic representative of the global population commonly affected by kidney stones.
Study Design: Participants were thoroughly informed about the study procedures, and written consent was obtained before enrollment. The study followed participants over a 4 weeks period to monitor treatment efficacy and safety. Assessments were conducted before and after treatment to evaluate changes in stone size, symptom relief, and recurrence prevention. Any adverse events or complications were carefully documented and analyzed.
Observations and Results: This clinical trial evaluated the safety and efficacy of Calcury Tablets in managing renal stones in 50 participants (mean age: 47.3 years; BMI: 27.2). Significant reductions were observed in stone size (6.5 ± 1.8 mm to 4.0 ± 1.2 mm, p = 0.001), stone number (3.5 ± 1.4 to 2.1 ± 1.0, p= 0.01), and pain levels (VAS: 6.5 ± 2.0 to 3.2 ± 1.4, p= 0.001). Stone passage increased from 60% to 90% (p = 0.03), and urine pH improved from 5.8 ± 0.6 to 6.3 ± 0.5 (p = 0.05). Quality-of-life scores rose significantly (48.2 ± 8.5 to 65.1 ± 7.2, p = 0.001), alongside hydration improvements (2.0 ± 0.5 to 2.5 ± 0.6 L/day, p = 0.04). Laboratory parameters remained stable, indicating safety, with no significant impact on renal, hepatic, or hematological markers.
Conclusion: The clinical evidence from this trial, combined with the promising preclinical findings on the individual herbs involved in the formulation, supports the use of Calcury Tablets as an effective, safe, and natural alternative for managing renal stones. This treatment offers a promising option for patients seeking a holistic approach compared to conventional medications
Evaluation of Cow Urine Distillate as a Natural Bio enhancer to improve the Efficacy of Anti-Tuberculosis Drugs against Mycobacterium Tuberculosis: A Research Protocol
No full textTuberculosis (TB) remains a global health challenge, exacerbated by drug resistance and limitations of current treatments like Isoniazid and Rifampicin. These therapies are associated with toxicity, prolonged treatment duration, and poor patient adherence. Cow Urine Distillate (CUD), an Ayurvedic remedy, has demonstrated bio-enhancing properties by improving drug absorption and therapeutic efficacy in various models. This study aims to evaluate the bio-enhancing effects of CUD on Isoniazid and Rifampicin. It will assess the safety and efficacy of the combination through in vitro and in vivo experiments, focusing on drug bioavailability, bacterial clearance, and toxicity reduction. The study will employ in vitro assays to determine the anti-mycobacterial effects of Isoniazid and Rifampicin alone and in combination with CUD. Serial dilution techniques will be used to establish the Minimum Inhibitory Concentrations (MICs). The impact of CUD on drug bioavailability and intracellular activity will be examined using MTB or M. bovis BCG cultures. Additionally, cytotoxicity assays will assess the safety profile of the combination. Statistical analysis will validate the significance of the findings. It is anticipated that combining CUD with Isoniazid and Rifampicin will enhance antibacterial activity, reduce MIC values, and improve drug bioavailability. Furthermore, the combination is expected to exhibit lower toxicity, potentially leading to safer and more effective TB treatment. This study aims to provide scientific validation for the use of CUD as a bio-enhancer for anti-TB drugs contributing to new adjunct therapies, improving TB treatment efficacy, accessibility, and combating drug-resistant strains
Shiroabhyang - By an Ayurvedic Essential Oils
No full textBackground: Hair is the symbol of beauty in all humans either female or male, everyone always tries to protect it anyways. In modern era due to imbalance lifestyle, stressful environment, bad eating habits and many psychological factors which makes hair compromised. Shiroabhyang is technique comes under Dincharya, which is getting erase day by day. Shiroabhyang with an essential oil increase skin permeability of scalp, hair growth, gives protection and fight from many hair health issues. Essential oils taken great interest among the herbal cosmetics in market i.e. rosemary oil (antibacterial and antioxidant properties), lavender oil (stimulates hair growth), eucalyptus oil (anti-inflammatory properties), peppermint oil (relieves itching and burning sensation of scalp), they have natural source with beneficial active ingredient which gives protection to our hair and recovery form hair issues. So, everyone should imply this practice in their daily routine. Aims and Objective: The purpose of this review is to resolve hair problems through Shiroabhyang with Ayurveda oil formulations. Methods: Literary aspects of the study will be collected from the classical texts of Ayurveda and modern text updated, recent medical journals and authentic websites. Observations and Results: By practicing Shiroabhyanga with essential oil, improves blood circulation, provides essential proteins required for nourishment, heals the damaged hair and improves the quality of hair. It was also noticed that on application of oil in the hair shaft, it enhances the colour and texture of hair. Conclusion: Shiroabhayang with essential oils gives protection and recovery from hair issues
The Role of Yoga and Meditation in Maternal Health: A Comprehensive Review During Pregnancy
No full textYoga is a term derived from the Sanskrit term “Yuj”, which means to merge or to unite. That can be conceptualized as mind and body practice. The term Yoga collectively would be used in reference to the physical movements accompanying with breathing exercises and the mental relaxation or meditation. Pregnancy is said to be the state in which mother goes through various physiological as well as psychological changes which may create certain hindrance in leading a normal life to a pregnant mother. Practicing Yoga during pregnancy provides a great range of emotional regulation, develops strong compassion to the unborn child, and gives the capacity to pregnant woman to adjust the inner and outer changes flexibly and minimizes the complications of pregnancy. Yoga is said to be a low impact, intentional and readily modifiable exercise making it suitable for pregnant women. The most assessed pregnancy-related factors include stress, anxiety, depression, pregnancy and labor pain and sleep. Yoga has been practiced for thousands of years known for its ability to strengthen the social, physical, and mental health of women and emerged as a complementary antenatal practice among the pregnant women. This article is an approach to Yoga in Pregnancy can improve the course of pregnancy and pregnancy outcomes as well
Understanding Udavarta Yonivyapad in the context of Primary Dysmenorrhea: A Comprehensive Review
No full textUdavartini Yonivyapad is one of the twenty gynecological illnesses recorded in Ayurvedic texts. The cause is worsened Apana Vata, which causes menstrual blood to flow upward. Udavartini, or upward movement, is the term for this ailment since the menstrual blood flows in the opposite way. The Madhukosha commentary indicates that the agony in Udavartini is caused by the Vayu\u27s all-around movement. All the causes (Nidana), symptoms (Rupa), pathogenesis (Samprapti), remedies (Chikitsa), and Pathya-Apathya of have been discussed in Ayurvedic classics like Charak Samhita, Shushruta Samhita, and others. Udavartini Yonivyapada (painful menstruation) is a frequent female reproductive system condition that hinders daily activities during menstruation. Thus, there is need to understand the disease and adopt measures to prevent it