Journal of Ayurveda and Integrated Medical Sciences (JAIMS)
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Management of Smack/Opium Addiction through Ayurveda Intervention : A Case Series
Get PDFOpium and its derivative addiction are rampant in western Rajasthan, because it is easily available. Opioids, which include heroin (or its impure form, smack or brown sugar), a range of medicinal opioids, are used by about 2.1% of the population in India. Opium was first described by Acharya Bhavprakasha, Properties are Tikta and Kashay Rasa, Laghu, Ruksha, Sukshma, Vyavayi, Vikasi, Vedanasthapana, Nindrajanana, Shothahara and Aakshepahara. The opium-derived addictions withdrawal symptoms such as nausea, vomiting, diarrhoea, chills, body ache, sleeplessness and flu-like symptoms begin, these symptoms can grow severe enough to necessitate emergency medical attention, and in extreme situations, they might have life-threatening consequences for the users a result of respiration depression, and pupil dilation in the later stages. Diagnosis: The assessment was based on Clinical Opiate Withdrawal Scale (cows) before and after the treatment. Intervention: Effect have been applied to depict 5 cases of opium addiction in form of series who have been treated with Sameergaja Kerari Rasa in the tapering method (Padanshika Krama) starting with the dose of 375 mg along with Vishatinduka Vati dose of 125 mg twice a day along with Panchakarma procedures, Abhayanga, Swedana and Shirodhara for a period of 1 month. Result: Reduction in cows scale was observed, about 75-80% of symptoms subsided in all cases and the results have been reported very encouraging within a period of twenty to thirty days. Conclusion: Ayurveda treatment can be an effective and safe solution for opium/smack addictions
A Multidimensional Integrated approach towards PCOS - Need of the Hour
Get PDFDue to the rapidly changing lifestyles, habits and environmental conditions a veraciously growing picture of PCOS is emerging. The estimated prevalence in India is ranged from 3.7% to 22.5%.[1] PCOS is a common hormonal condition that affects women of reproductive age. It usually starts during adolescence but symptoms may fluctuate over time. It has varying symptoms ranging from irregular menses to chronic conditions like endometrial CA, heart diseases, etc. This article primarily deals with the various approaches which can be applied to treat PCOS depending upon patient’s condition and interest
Etiopathological and Survey Study of Sthaulya Roga w.s.r. to Hypothyroidism : A Questionnaire Based Survey
Get PDFObesity is one of the primary lifestyle disorders which leads to risk the various cardiovascular disease. In Ayurveda obesity has been described by the term Sthaulya Roga. In modern era hypothyroidism is associated with obesity. In India, prevalence of hypothyroidism in obese individual is 11.6%. Here in this survey study, questionnaire based on Nidana (etiology), Roopa (symptoms) of Sthaulya Roga according to Ayurveda and questionnaire based on symptoms of hypothyroidism has been made to bring out the relation between Sthaulya Roga and hypothyroidism which has been calculated by percentage. The method of study, result analysis, discussion and observation of the survey study has been presented. Such study will help to treat hypothyroidism based obesity by Ayurvedic therapy
Role of Ayurveda in the Prevention of Communicable Diseases
Get PDFIntroduction: Infectious or communicable diseases can be defined as illness caused by another living agent or its products that spread from person to person and can be a cause of emergency. Ayurveda do believe in microorganisms i.e., Krimi, but emphasized more on body’s response and occurrence of disease i.e. Vyadhikshamatwa. Communicable diseases well described by Acharya Sushrut termed Aupasargika Roga for epidemic condition, spread through contacts. Acharya Charak coined Janapadodhvansa Roga for pandemic conditions involving rapid outbreak on large scale. Because of improper diet, lack of exercise, stress, fast food, junk food & global warming overall health status of individuals is poor and they are prone to communicable diseases like Covid 19, H1N1 Influenza creating a burden over health care system. Aims & Objectives: To spread the awareness about Ayurvedic approach towards preventing communicable diseases. And to study the role of Ahara and Vihara in prevention of communicable diseases. Result & Conclusion: A healthy and long peaceful life devoid of any disease is the main aim of Ayurveda through implementation of Dincharaya, Rutucharya, Sadvritta is important for physical and mental health. With the help of Shodhan (Panchakarma), Shamana (Aushadha) & Rasayana these diseases can be cured. In this literary work, efforts have been made to find out how Ayurveda can help to prevent communicable diseases
Role of Virechana Karma in Poly Cystic Ovarian Syndrome - A Case Study
Get PDFBackground: Polycystic Ovarian Syndrome is a prevalent endocrine disorder among women of reproductive age, characterized by hormonal imbalances, irregular menstrual cycles, insulin resistance and presence of ovarian cyst. Conventional treatments for PCOS often focus on symptoms management but ayurvedic medicine offers a holistic approach that aims at addressing the root cause. Virechana Karma is an essential treatment modality in ayurveda for managing hormonal imbalances and detoxifying the body. Materials and Methods: In the present study a 25 years old female diagnosed with PCOS was treated with Shodhana Karma as Snehapan, Sarwanga Abhyanga, Swedana followed by Virechana Karma and Shamana Chikitsa given after discharge. Result: After the given treatment patient has got significant relief in her symptoms and showed significant difference in her subsequent USG report. Conclusion: The role of Virechana Karma in the treatment of PCOS, emphasizing its ability to regulate the Dosha, particularly Kapha and Pitta, which are considered to be imbalanced in PCOS. By eliminating ama from the body and promoting Agni, Virechana helps restore hormonal balance, improve insulin sensitivity and regulate the menstrual cycle. Hence, Virechana Karma represents a promising and integrative therapeutic option in the present study
Network Pharmacology and AI-Based Analysis of Dioscorea bulbifera Linn. in Scopolamine-Induced Memory Impairment in OVX Rats: Insights into Estrogen-Linked Alzheimer’s Disease
No full textAlzheimer\u27s disease (AD) is one of the leading causes of dementia characterized by cognitive decline. Women are more likely to develop (AD) than men, possibly because estrogen levels drop after menopause. This study aimed to elucidate the effect of Dioscorea bulbifera (DB) extract on scopolamine-induced memory impairment in rats and to decipher the molecular mechanism of its phytoconstituents using an integrated network pharmacology and artificial intelligence-based approach. Memory function was evaluated using the Elevated Plus Maze (EPM) and Morris Water Maze (MWM) tests. Scopolamine administration significantly increased transfer latencies in the EPM and escape latencies in the MWM compared to the control group. However, co-administration of DB extract with scopolamine reversed these effects, showing decreased transfer latencies and escape latencies, indicating improved memory. Furthermore, the DB extract restored the time spent searching the target quadrant in the MWM probe trial session, which was impaired by scopolamine. Acetylcholine (Ach) and serum estradiol levels were quantified with enzyme-linked immunosorbent assay (ELISA) on Ovx rats induced with scopolamine to have memory deficits. With predicted DB targets and a collection of AD-related genes, 132 putative targets, 68 direct regulatory targets, and 25 potential regulatory targets of DB were identified for the treatment of AD. Pathway-enrichment analysis for the potential regulatory targets indicated that neurotransmitter clearance in the synaptic cleft was pivotal in the treatment of AD with DB, molecular docking verified interactions between the core targets (ESR1, APP, GSK3β, BACE1, AChE, and MAOB) and the active ingredients
Pharmaceutical advancement of Trunamooladi Kashaya into Trunamooladi Granules and its Galactogogue Activity in lactating mother w.s.r. to Stanyakshaya - A Randomised Controlled Trial
No full textIntroduction: Trunmooladi Granules are purely an herbal formulation, indicated for Internal administration in the management of ‘Stanyakshay’ or Lactation Insufficiency. 30% to 40% of people may suffer from lactation deficit in Asian and tropical nations like India. Aim and Objectives: To modify the Trunmooladi kashay into Trunmooladi Granules and to study its Galactogogue activity in lactating mother Materials & Methods: Trunmooladi Kwatha and Trunmooladi Granules will be prepared as per classical reference. The prepared formulation will be assessed with organoleptic characters and physicochemical parameters. Clinical study will be carried out in 2 groups where each group will receive Trunmooladi Granules and standard drug Shatavari Granules and will be evaluated for their results on Stanyakshaya (Lactation Insuffiency). Results: The analytical parameters will be assessed to establish pharmaceutical standardization. The result of clinical study will be drawn from the mentioned assessment criteria. Statistical analysis will be done accordingly. Conclusion: If significant positive results are obtained in this work, then it will be a valuable contribution and evidence that the drug Trunmooladi Granules is effective as galactogogue agent in Lactation Insufficiency
Analytical study of Sarivadi decoction - An Ayurveda remedy for management of ADHD children
No full textIntroduction: Sarivadi decoction is a polyherbal formulation, it is used by Piththaja Unmada Chikithsa in Sri Lankan Traditional Medical system mention on Deshiya Chikithsa Sangraha (page no. 633) six herbs included decoction of Sarivadi ingredients are Sariva (Hemidesmus indicus), Shatavari (Asparagus racemosus willd), Yashtimadu (Glycyrrhiza glabra), Draksha (Vitis vinifera), Shwetha Chandana (Santalum album),Musthaka, (Cyperus rotundus). Aim of the study: Importance of standardization and quality check of herbal drugs can be passed through the various analytical studies. Such as physico-chemical, Phyto chemical, microbial analysis, heavy metals etc. Materials and Methods: Pre-authenticated raw drugs were procured, Sarivadi decoction was prepared at the pharmacy, National Ayurveda Teaching Hospital in Borella. Organoleptic parameters, Heavy metals analysis, Thin Layer Chromatography (TLC) of Sarivadi decoction were done at industrial of Technical Institute, Sri Lanka and Physico Chemical Analysis and Microbial Analysis of Sarivadi Decoction were done at botany laboratory in Science Faculty University of Colombo. Results: In pharmaceutical parameters, the pH value was 5.52, sugar concentration was 10.89 mg/ml, Titratable acidity value was 4.7 x 10-3 moldm-3, TLC values of the standard mixture of raw materials of Sarivadi decoction at 254 nm and at 366 nm showed 14 and 14 spots respectively; and TLC values of sample of Sarivadi decoction at 254 nm and at 366 nm showed 10 spots each. In microbial analysis of Sarivadi Decoction showed no any contamination upto 14 days. Conclusion: This study has generated preliminary data on physicochemical parameters, TLC, heavy metal analysis and microscopic analysis of Sarivadi Decoction. This fingerprinting can be useful for future researchers to reproduce this formulation and to establish the QC parameter of Sarivadi Decoction
Role of Agni in Stree Vandhyatwa
No full textInfertility, as defined in Ayurveda, is the inability to achieve a successful pregnancy despite of regular intercourse over a period of 12 months.[1] The condition is multifactorial, and Ayurveda offers a holistic approach to ensure a normal pregnancy by maintaining the balance of Garbha Sambhavasamagri’s and stable mental state. Sushrutha had explained the Garbha Sambavasamagri (factors responsible for successful pregnancy) in detail. They are Ritu (The appropriate timing or fertile period), Kshetra (The health and readiness of the reproductive organs), Ambu (Nutritional factors and the availability of a conducive fluid environment), and Beejam (The health and quality of ovum and sperm). Any abnormality in these factors can lead to infertility. Additionally Charaka emphasized the importance of peaceful mind “Soumanasyamgarbhadharanam”[2] fundamental remedy for conception. Maintaining the proper functioning of Vata Dosha is equally essential, both for achieving conception and for sustaining a healthy pregnancy. A balanced Agni (digestive fire) is considered the cornerstone of treatment in Ayurveda. The optimization of Agni ensures proper digestion, absorption of nutrients, and overall physiological balance. The Bhagavad Gita beautifully conveys this concept, stating that the divine resides within humans as Agni, which, in collaboration with Prana and Apana (vital energies), governs all digestive activities. Ayurveda recognizes 13 types of Agni, each responsible for various metabolic and physiological processes. When functioning optimally, Agni sustains life, enhances vitality (Ojas), promotes a healthy complexion (Prabha), and ensures well-being. Thus, balancing Agni is key to addressing not only infertility but also the underlying imbalances that contribute to various pathologies in the body
Synergistic Effect of Vranabasti with Nirgundi Taila and Guduchyadi Kashaya in Healing of Dushtavrana - A Case Study
No full textDushta Vrana (chronic ulcer) is a frequently encountered problem in present era produced commonly as a complication of trauma or pathologic affront and it causes long term agony to the patient. The break in continuity of skin or underlying tissue resulting in a persistent scar is called as Vrana (wound). Dushta Vrana may be understood as a chronic ulcer, which is clinically persisting for more than 6 weeks. The prevalence rate of chronic ulcer in a developing country is almost 2%. Due to prolonged hospitalisation, there is a reduction in the quality of life in patients and a great deal of financial burden with almost rates going up to 3% of total health care budget.[1] Acharya Sushruta mentioned 60 Upakramas for the management of Vrana[2] and local application of Nirgundi Taila Vrana Basti is one among them. The local application of Vrana Basti is one of the best substitutes for chronic wound healing & the Nirgundi Taila is anti-inflammatory, analgesic, antibacterial and also have better Shodhana & Ropana effect. A case report of 40 year old man, who presented with complaints of an open chronic non healing ulcer on the lateral aspect of the right shoulder joint associated with pain, discharge, slough, foul smell, oedema and discolouration on the skin has visited to Shalya Tantra OPD, Ramakrishna Ayurvedic Medical College, Hospital and Research Centre, Bangalore