Journal of Ayurveda and Integrated Medical Sciences (JAIMS)
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    A Review Study on Ancient Drug - Mukta

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    For thousands of years, Rasa Shastra, also known as Ancient Indian alchemy, has been a part of the medical field that has benefited humanity. In Rasa Shastra, the Ancient Alchemists were particularly interested in Rasa, which means Mercury. Rasa Shastra also studies and prepares different herbo-mineral compounds. And the safe use of Mercurial preparations as medicines from many years, Rasa Shastra also deals with study and the preparation of other herbo-mineral chemicals using various plant drugs and animal origin. One of the drugs, the most widely used in Rasa Shastra is Mukta or Pearl. There are various categories or groups of drugs (Varga) used in Rasa Shastra viz. Maharasas, Uparasas etc. and Mukta is divided under the Ratna (precious treasures) Varga. Mukta, also known as Pearl, is one of the medications that is most frequently utilized in Rasa Shastra. Mukta is a spherical, solid black, dazzling white fish that lives in the water. Its advantageous appearance makes it a common ingredient in apparel, cosmetics, and jewellery. It is created by encircling the center nucleus with many layers of conchiolin and calcium carbonate. Classics of Rasa Shastra state that Madhura, Sheeta, and Laghu belong to Mukta. Additionally, it is frequently used as a potent Pitta Shamaka. Procedures for purification and Pishti are also mentioned in the classics of Rasa Shastra, which makes pearls extremely effective for curing illnesses. In Amlapitta, Jwara and Daha, Mukta is widely used in various forms. The aim of the study is to have a critical review on the conceptual study of Mukta

    Clinical trial to evaluate the safety and efficacy of Vedistry Haldi + Tablet in skin disease

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    Background: Turmeric (Curcuma longa) is widely recognized for its medicinal properties, primarily due to its active compound, curcumin. Curcumin exhibits anti-inflammatory, antimicrobial, antioxidant, and anti-cancer effects, making it beneficial for skin health. It has traditionally been used to treat skin conditions such as acne, eczema, and inflammation. Objective: To evaluate the clinical efficacy and safety of Vedistry Haldi + Tablet in managing skin health. Methods: This phase 3, non-randomized, prospective open-label clinical trial evaluated the safety and efficacy of Vedistry Haldi + Tablet in 300 participants aged 18-65 years with chronic or recurrent skin conditions, including eczema, psoriasis, and acne. Participants were treated daily for 3 months. Result: The clinical study evaluating Vedistry Haldi + Tablet demonstrated significant improvements in skin health among participants aged 18-65 years with chronic dermatological conditions. Participants showed reduced acne severity, hyperpigmentation, inflammation, and itching, along with enhanced skin hydration, texture, and tone. Quality of life scores improved notably, and serum markers like Vitamin C and antioxidants were elevated, indicating positive effects on skin health. Importantly, laboratory tests revealed no significant adverse changes in haematological, liver, or renal function, confirming the treatment’s safety. Vedistry Haldi + Tablet proved to be an effective and safe option for improving skin health and managing dermatological symptoms. Conclusion: Overall, Vedistry Haldi + Tablet demonstrated substantial benefits in improving skin health without significant adverse effects, suggesting its potential as a safe and effective option for managing dermatological concerns

    Assessing Ayurvedic treatment efficacy in Chronic Kidney Disease - A Case Study

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    Evidence-based Ayurvedic practices and clinical studies have been increasingly utilized to assess the efficacy of Ayurvedic treatments in managing chronic kidney disease (CKD), highlighting their potential as complementary approaches in improving patient outcomes. Chronic kidney disease (CKD) has become a focal point in recent years due to its increasing prevalence and the heightened risks of cardiovascular issues and mortality associated with it. In certain instances, CKD can advance to end-stage renal disease, necessitating treatments such as kidney transplantation or dialysis. Although the Kidney Disease Outcomes Quality Initiative (K/DOQI) has established guidelines for the diagnosis and classification of CKD, traditional treatment methods often fall short. Kidney transplantation is associated with the best outcomes and enhanced quality of life; however, not all patients qualify, and the assessment process is intricate, compounded by a significant shortage of available organs. Additionally, transplantation typically requires a hospital stay of 4 to 7 days and lifelong immunosuppressive therapy, which necessitates meticulous monitoring of blood levels and raises the risk of infections and certain cancers. While dialysis serves as an alternative, its risk-benefit ratio can limit its overall effectiveness. This is a case report of a male patient having age 64 years who was newly diagnosed as CKD & on regular conservative treatment in modern science. However, due to persistent increase in value of renal profile, he approached to superspecialist OPD Pt. KLS Bhopal. Conversely, a comprehensive Ayurvedic approach seeks to alleviate symptoms, slow CKD progression, and potentially eliminate the need for dialysis. Ayurvedic treatments such as Veertharvayadi Ghana Kwath and Shatvaryadi Ghana Vati have demonstrated potential in enhancing kidney health and rectifying underlying imbalances. For adults experiencing compromised kidney function, particularly those whose conditions have not responded well to diuretics, antihypertensive drugs, or angiotensin-converting enzyme inhibitors, these Ayurvedic solutions present viable alternatives. They have resulted in clinically significant improvements in serum creatinine levels, glomerular filtration rate (GFR), blood urea, serum uric acid, and electrolyte balance

    Phytoextracts in Dentistry from Prevention to Therapy - A Review

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    Dental diseases are major public health problems and are the most common cause of tooth loss in adults. However, every disease is preventable if diagnosed at the earliest and there are many ways for prevention of dental diseases like use of drugs, invasive and noninvasive techniques. The field of dentistry also has begun to exploit herbs as one of the cost-effective ways of prevention. Phytomedicine may be defined as a medicine derived from plants in their original state and standardized for use in a dosage regimen. Some of the commonly available herbs are clove oil, green tea, turmeric, aloe-Vera, Triphala, neem, peppermint and oregano which exhibit excellent biological properties like- Antimicrobial agents, Anti-inflammatory agents, antioxidant and sedative. Plant extracts have the potential to act as prophylactic or therapeutic agents for soft tissue and hard tissue conditions. This review article explores the application of phytoextracts for dental disease prevention and emphasizes their integration within the framework of Evidence-Based Dentistry (EBD). Through a comprehensive literature search conducted on the PubMed database, this review synthesizes findings from various studies on phytoextracts, highlighting their potential in primary prevention methods in dentistry. It underscores the importance of EBD in validating the efficacy and safety of phytoextracts, ensuring that clinical practices are grounded in robust scientific evidence. This bird’s eye view of the current literature reveals a significant need for more rigorous and detailed research to fully harness the benefits of phytoextracts in dental care

    Management of Shwitra (Vitiligo) through the Holistic Approach of Ayurveda

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    Vitiligo is a chronic skin disorder characterized by the progressive loss of melanocytes, leading to the formation of depigmented patches on the skin. Ayurveda describes in detail the etiology, symptoms and management of Vitiligo under the disease named Shwitra. While conventional treatments often focus on symptom management, Ayurveda, offers a holistic approach to restoring skin pigmentation and addressing the root causes of the disorder. The disease results from increased oxidative stress brought on by chronic inflammation, which in turn causes greater melanocyte destruction. By examining both classical Ayurvedic texts and contemporary clinical studies, this research highlights the potential benefits of personalized Ayurvedic treatments in promoting skin pigmentation, improving immune function, and managing oxidative stress. This is a case study of 17yr old male patient who came to the OPD with the complaints of white patches on face (below both eyes), lips, neck, extensor aspect of right forearm and left-hand palm region since 2 years. The patient was given Shaman Chikitsa, Nidan Parivarjan, dietary modifications and lifestyle adjustments. Patient started regaining normal pigmentation of skin and is still under follow up for further treatment and for Apunarbhav Chikitsa

    A Scientific Review on Dashavidha Atura Pariksha: The Tenfold Examination in Ayurveda

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    Ayurveda is a science based on detailed examination (Pariksha) and personalized medicine. Dashavidha Atura Pariksha (tenfold patient examination) is a fundamental diagnostic tool described in Charaka Samhita, Vimana Sthana, Adhyaya 8. It assesses the patient\u27s constitution (Prakriti), pathological state (Vikriti), tissue quality (Sara), structural compactness (Samhanana), body measurements (Pramana), adaptability (Satmya), mental strength (Satva), digestive capacity (Aharashakti), physical endurance (Vyayama Shakti), and age (Vaya). This examination aids in diagnosis, prognosis, and personalized treatment planning. The approach aligns with modern medical perspectives, such as genomics and precision medicine. This article critically reviews each of the ten parameters with an emphasis on their clinical significance

    Efficacy of Durvadi Taila in Episiotomy Wound Healing: An Ayurvedic Perspective

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    Episiotomy, a surgical incision during childbirth, often poses challenges in wound healing, increasing maternal morbidity. Despite advancements in modern wound management, complications like infection, delayed healing, and discomfort remain common. Ayurveda offers a comprehensive approach to wound management, described under the umbrella of Vrana Chikitsa. Durvadi Taila, a classical Ayurvedic medicated oil formulation, is traditionally acclaimed for its Shodhana (cleansing) and Ropana (healing) properties. Comprising herbs like Durva (Cynodon dactylon) known for Raktasthambhana (hemostatic) and Vrana Ropana (wound healing) actions, Durvadi Taila presents a promising natural therapeutic option for enhancing episiotomy wound healing. This review critically evaluates the efficacy of Durvadi Taila based on classical Ayurvedic literature, pharmacological actions of its ingredients, and contemporary research evidence. Preclinical studies demonstrate its antimicrobial, anti-inflammatory, and collagen-promoting activities, while preliminary clinical studies suggest faster wound contraction, better epithelialization, and reduced infection rates. The holistic action of Durvadi Taila aligns with the principles of Shodhana and Ropana, crucial for effective wound management. Additionally, its easy availability, biocompatibility, and minimal side effects make it a favorable alternative or adjunct to conventional treatments. However, challenges such as standardization, quality control, and lack of large-scale randomized controlled trials warrant attention. Integrating Durvadi Taila into postpartum care protocols could significantly benefit maternal health outcomes. Further extensive clinical validation is essential to establish its efficacy and safety conclusively

    Management of Hypothyroidism with Ayurveda - A Case Study

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    The most prevalent endocrine disorders in the world are thyroid issues. TSH is the most practical physiological indicator of thyroid gland function and is crucial in regulating the thyroid axis. One major factor contributing to the rise in endocrine disorders, including thyroid disorders, may be a sedentary lifestyle and poor eating habits. Numerous Kaphaja Nanatmaja Vikaras are thought to be signs of hypothyroidism. Multiple systems are affected by the clinico-pathological condition known as hypothyroidism, which necessitates multimodal treatment. Shamana Chikitsa implemented the treatment plan in order to combat the pathophysiology. Even after two months, the patient\u27s symptoms had completely disappeared. Laboratory tests were conducted during routine follow-ups and subsequent treatments

    Ayurvedic and Modern Surgical Approaches to Non-Healing Wounds: A Comprehensive Review

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    Non-healing wounds present a significant challenge in surgical practice, requiring a multidisciplinary approach for effective management. This review explores the principles and practices of wound management in Ayurveda, focusing on Vrana Ropana (wound healing) and modern surgical techniques. The article aims to highlight integrative approaches that can optimize patient outcomes through a deeper understanding of both traditional and contemporary methodologies

    Ubhayparimarjan Chikitsa in the management of Madhumehjanya Dustavrana (Diabetic Foot Ulcer): Case Study

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    Diabetic foot ulcer is the most common complication of diabetes mellitus with a poor prognosis due to micro and macro vascular change as a result of an uncontrolled sugar level. According to Ayurveda, diabetic foot ulcers are known as Dusht Vran because they do not heal and have unpleasant-smelling wounds.  In this case study, A 70-year-old male patient newly diagnosed case of diabetes mellitus with complaints of severe itching, swelling and scaling, cracks, with mild bleeding, pus and watery discharge on bilateral lower limb with associated complaints Pada Daha (burning sensation in feet). He was accidentally diagnosed with type-2 Diabetes mellitus after investigation, FBS (212.4 mg/dl) and HbA1c (10.5 %). The management of diabetic foot ulcers includes multimodal approaches like blood sugar level control, infection control, debridement of wound, vascular assessment and proper wound care. The patient was treated on the line of Ubhayparimarjan Chikitsa. Bahirparimarjana Chikitsa: - Nimba Patra Kashay for Padaprakshalana Aragwadha Patra Kalka for Lepa. Anthaparimarjana Chikitsa: Shodhana Chikitsa: Panchatiktapancha Prasritika Basti for 16 days. Shaman Chikitsa: Phalatrikadi Kwatha, Kaishore Guggulu, Madhumehari Churna etc. for three months. The wound was effectively managed through Ayurvedic intervention, resulting in significant improvement in clinical signs, symptoms, and normalization of laboratory parameters

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