Journal of Ayurveda and Integrated Medical Sciences (JAIMS)
Not a member yet
4014 research outputs found
Sort by
Macroscopic and Physicochemical Description of Triphaladi Yoga Capsules
No full textTriphaladi Yoga is a classical Ayurvedic formulation containing Haritaki, Vibhitaki, Aamalaki, Yashtimadhu, and Lauha Bhasma. This study aimed to evaluate its macroscopic characteristics and physicochemical parameters to ensure quality, purity, and standardization. Laboratory analysis included sensory evaluation, microscopy, ash values, extractive values, pH, qualitative identification tests, and Thin Layer Chromatography (TLC). Results confirmed the presence of characteristic phytoconstituents and mineral components, validating the identity and purity of the formulation. The findings support the therapeutic potential and safety of Triphaladi Yoga and highlight its relevance in evidence-based Ayurvedic practice
Ayurvedic Management of Post-Chikungunya Arthritis using Kshara Basti and Nirabhisankhita Basti - A Case Report
No full textChikungunya which is a virus infection is frequently associated with long-lasting musculoskeletal complications, particularly arthritis, which significantly impacts patients’ quality of life. Ayurvedic texts describe a condition akin to post-viral arthritis as Vata-Kaphaja Jwara followed by Sandhigata Vata. This case report presents the Ayurvedic management of a 51-year-old female patient with post-Chikungunya arthritis persisting for 10 months. Treatment included a sequential course of Kshara Basti for 8 days followed by Nirabhisankhita Basti for 8 days. Significant improvements in pain, stiffness, swelling, and joint function were observed without adverse effects. This case highlights the potential of Ayurvedic Basti therapy in managing chronic post-viral arthritis
Phytochemical Profiling of Frequently Cited Medoroga Dravyas in Bhaishajya Ratnavali with Reference to Obesity and Dyslipidaemia Management
No full textMedoroga, characterised by the excessive accumulation of Meda (adipose tissue), is associated with obesity and lipid metabolism disorders in modern medicine. This review analysed formulations from Bhaishajya Ratnavali Medoroga Adhikara, identifying common Dravyas and examining their phytochemical constituents relevant to obesity and dyslipidaemia management. The common Dravyas include Triphala, Trikatu, Trimada, Hingu, Guggulu, and Madhu. Phytochemical analysis revealed the presence of flavonoids, alkaloids, saponins, triterpenoids, and tannins in these Dravyas. These compounds exert anti-obesity effects by modulating lipid metabolism, suppressing appetite, increasing energy expenditure, and regulating gut microbiota. Flavonoids decrease lipogenesis and increase lipolysis. Alkaloids, such as berberine, improve lipid profiles. Saponins regulate lipid metabolism and improve adipogenesis. Triterpenoids, such as Alisol A, decrease lipid levels and alleviate glucose metabolism disorders. Tannins prevent the oxidation of low-density lipoproteins (LDL), reduce blood pressure, and enhance vascular function. Understanding these phytochemical mechanisms provides insights into the use of traditional Ayurvedic Dravyas for managing obesity and dyslipidaemia, offering potential avenues for the development targeted therapeutic strategies. These findings suggest the potential of Ayurvedic Dravyas in developing targeted therapeutic strategies for obesity and dyslipidaemia management
Psychophysiology of the Gut-Brain Axis in Ayurveda: Role of Agni, Vata and Sattva
No full textThe gut–brain axis (GBA) represents a complex bidirectional communication network that integrates the gastrointestinal tract and the central nervous system.[11] Numerous interrelated pathways, including as immunological, endocrine, neurological, and microbial systems, are part of its physiology. The vagus nerve and the enteric nervous system, which carry sensory and motor data from the gut to the brain, are the main pathways via which neural signaling takes place.[15] Gastrointestinal hormones that affect hunger, satiety, and metabolic processes, including ghrelin, cholecystokinin, glucagon-like peptide-1, and peptide YY, mediate endocrine control. By modulating neuroinflammatory responses and preserving mucosal integrity, the immune system contributes through cytokine signalling. Furthermore, metabolites that affect both enteric and central neuronal circuits are produced by the gut microbiota, including short-chain fatty acids and neurotransmitter precursors.[21] Together, these interconnected networks control immunological homeostasis, stress response, hunger, motility, digestion, and higher cognitive processes. Disorders ranging from obesity and irritable bowel syndrome to anxiety, depression, and neurodegenerative illnesses have all been linked to dysregulation of the GBA. Thus, a physiological framework connecting gastrointestinal health to systemic and cognitive outcomes is provided by the gut–brain axis
Conservative Ayurvedic Management of Trigger Finger (Stenosing Tenosynovitis) in a Diabetic Patient using Snigdha Agnikarma: A Single Case Report
No full textBackground: Trigger Finger (stenosing tenosynovitis) is a common musculoskeletal disorder that can be correlated with Snayugata Vata in Ayurvedic parlance. Classical texts, including the Sushruta Samhita, describe characteristic symptoms such as Stambha (stiffness), Shoola (pain), and Kampa (tremor), and recommend Agnikarma as a specific line of management in disorders of Snayu (tendons and ligaments). Management becomes particularly challenging in diabetic patients due to delayed healing and increased surgical risks.
Case Presentation: A 71-year-old male with a nine-year history of type 2 diabetes mellitus, managed with Glipizide 5 mg twice daily, presented with an eight-month history of pain, swelling, and locking of the right ring finger. Clinical examination confirmed Trigger Finger (Quinnell grade II), which was classified as Snayugata Vata from the Ayurvedic perspective.
Intervention: Snigdha Agnikarma (therapeutic heat application using an unctuous medium) was performed using Nirgundi Taila. The procedure was administered once weekly for two consecutive weeks in the Kaya Chikitsa OPD of Sardar Ayurved College, Mehsana, Gujarat. No other local interventions were given during this period.
Outcome: The patient reported complete relief from pain, stiffness, and finger locking after two sessions. Objective assessment showed a full range of motion with no tenderness or triggering. Follow-up at one month revealed sustained improvement without recurrence or adverse effects.
Conclusion: This case highlights the potential of Snigdha Agnikarma as a safe, effective, and non-surgical treatment modality for Trigger Finger in diabetic patients. Further controlled studies are warranted to validate these findings and explore broader clinical applications
Revisiting Haridra of Lekhaniya Mahakashaya: A Classical Herb with Contemporary Evidence for the Management of Obesity and Dyslipidemia
No full textObesity and dyslipidemia are interrelated metabolic disorders that significantly contribute to the global burden of cardiovascular diseases, type 2 diabetes, and metabolic syndrome. Current pharmacological treatments often provide limited long-term benefits and may lead to adverse effects, prompting interest in safer, holistic alternatives such as those offered by Ayurveda. Haridra (Curcuma longa Linn.), a prominent herb in the Ayurvedic Lekhaniya Mahakashaya group, has traditionally been used to treat Sthaulya (obesity) and Medoroga (lipid disorders) due to its Lekhana (fat-reducing) and Medohara (anti-obesity) properties. Modern research attributes these effects primarily to curcumin, the principal bioactive compound in turmeric, which exhibits anti-inflammatory, antioxidant, and lipid-regulating actions. Curcumin modulates key metabolic pathways by inhibiting adipocyte differentiation, reducing lipid accumulation, suppressing pro-inflammatory cytokines, and activating AMPK and PPAR-γ signalling. These mechanisms contribute to improved insulin sensitivity and enhanced lipid metabolism. Numerous preclinical and clinical studies support curcumin’s efficacy in lowering triglycerides, LDL-C, and total cholesterol, while increasing HDL-C and adiponectin levels. Evidence also indicates reductions in body weight, fat mass, and markers of oxidative stress in both animal models and human subjects. These findings align with Ayurvedic concepts and provide scientific validation for Haridra’s traditional use in managing metabolic disorders. In summary, Curcuma longa represents a promising integrative approach to addressing obesity and dyslipidemia. However further rigorous human trials are necessary to establish standardized dosages, enhance bioavailability, and confirm long-term safety, thereby facilitating its incorporation into contemporary clinical practice
A Critical Review of Patoladi Gana Dravyas from Sushruta Samhita as Antipyretic Agents
No full textA significant proportion of the global population relies on traditional medicine systems for primary health care, with Jawar (fever or pyrexia) being one of the most addressed conditions in such practice. In Ayurveda, Jwara is considered a Rasa Pradoshaja Vyadhi affecting both Sharira and Manas, primarily involving Agni Dushti, Ama accumulation, and Tridosha vitiation. Among the herb groupings (Ganas) mentioned in Sushruta Samhita, Patoladi Gana is a well-established cluster of Seven herbs - Patola (Trichosanthes dioica), Sweta Chandana (Santalum album), Rakta Chandan (Pterocarpus santalinus), Murva (Marsdenia tenacissima), Guduchi (Tinospora cordifolia), Patha (Cissampelos pareira), Katuki (Picrorhiza kurroa), - formulated specifically for the treatment of Jwara. These herbs, characterized by their Tikta Rasa act synergistically to pacify aggravated Pitta, detoxify Ama, kindle Agni, and purify Rakta. Pharmacologically, Patoladi Gana exhibits a wide spectrum of actions including antipyretic, anti-inflammatory, hepatoprotective, immunomodulatory, and antioxidant effects. Modern studies have validated the presence of bioactive compounds such as kutkin, berberine, santalol, and flavanoids, which act via mechanisms like cytokine inhibition, prostaglandin suppression, and liver enzyme regulation. Patoladi Gana is thus a scientifically and traditionally validated herbal formulation for the safe and effective management of fever. It not only reduces body temperature but also addresses its root causes - poor digestion, liver dysfunction, and immune imbalance. This review highlights its therapeutic potential, classical relevance, pharmacodynamics, and clinical applicability in febrile disorders
Chronic Cosmetic Toxicity through the Lens of Dooshivisha: An Integrative Ayurvedic Review
No full textAyurveda describes Dooshivisha as a form of latent or residual toxin that remains in the body for years, manifesting as chronic diseases when provoked by favourable conditions. In modern times, frequent exposure to synthetic cosmetics has led to an increase in allergic skin disorders such as contact urticaria, eczema, and dermatitis. The concept of Dooshivisha provides a meaningful Ayurvedic framework to understand these chronic toxic reactions. To explore the Ayurvedic concept of Dooshivisha and correlate its manifestations with modern cosmetic-induced allergic skin disorders, thereby highlighting the need for safer, holistic cosmetic practices.A qualitative, analytical review of classical Ayurvedic texts including Charaka Samhita, Sushruta Samhita, and Ashtanga Hridaya was conducted to identify references related to Dooshivisha and its dermatological symptoms. Modern dermatological and toxicological studies were also reviewed through indexed databases to identify cosmetic ingredients associated with contact urticaria and allergic skin toxicity. Dooshivisha is described as a weakened or partially neutralized toxin that becomes encapsulated in the body’s tissues, particularly Rakta Dhatu, and later manifests as skin disorders under favorable conditions. Common symptoms—such as itching, redness, swelling, and discoloration—closely resemble modern descriptions of contact urticaria and chronic allergic dermatitis. Several cosmetic ingredients, including p-phenylenediamine, phenoxyethanol, and benzophenone-3, have been identified as frequent allergens. The Ayurvedic concept of Dooshivisha provides a holistic interpretation of chronic cosmetic toxicity. Integrating Ayurvedic cosmetology with modern dermatological safety standards offers a sustainable approach to skincare that emphasizes prevention, detoxification, and natural formulations. Further clinical validation of classical Vishaghna and Kushtaghna formulations can contribute to developing safer and more effective cosmetic alternatives
Macroscopic and Physio-Chemical Description of an Ayurvedic Formulation Shigruadi Anjana
No full textShigruadi Anjana is a Ayurvedic formulation containing Moringa oleifera (Shigru), Azadirachta indica (Nimba), Berberis aristata (Daruharidra), Madhu (honey), and Saindhava Lavana (rock salt) which are known for its ocular benefits. The present study was conducted to analyze its macroscopic features, physico-chemical parameters, and identification using TLC. The pH was 4.92, loss on drying 4.59%, and refractive index was 1.468. TLC results confirmed the presence of marker compounds from Shigru, Nimba, and Daruharidra. These results provide a quality benchmark for the formulation and reinforce its traditional usage
Integrating Ayurvedic Tridosha Theory with Homeostasis - A Narrative Review
No full textThe human body consists of three essential components: Dosha, Dhatu, and Mala. Doshas are the fundamental elements responsible for regulating homeostasis in the body. Acharya Vagbhata states that ‘Doshasamayam Arogta’ health is preserved when the Doshas remain in a state of balance, whereas any disruption in this equilibrium leads to the onset of disease. These three vital bio-energies (Vata, Pitta and Kapha) forms the constitution of the physical body. It maintains the personality of person at physical as well as mental level. Each Dosha has their own specific qualities. Just as the moon, sun and air sustain the cosmos through nourishing, receiving and dispersing energies respectively, the three Doshas Kapha, Pitta and Vata govern essential physiological functions to maintain homeostasis in the human body. Kapha ensures fluid balance, structural stability, and lubrication. Pitta regulates metabolic processes, including digestion and the biochemical transformation of nutrients. Vata controls all forms of bodily movement, including respiration, circulation, and neural communication. Together, these Doshas coordinate to sustain internal balance and physiological harmony. Understanding Tridosha helps in aligning daily habits with natural cycles, supporting overall health and homeostasis. A person’s health depends on whether the three Doshas Vata, Pitta and Kapha are in balance or not. These Doshas help control all the body’s functions, so understanding how they work gives a complete way to keep the body in balance. Following daily routines that match the natural cycle of these Doshas & help in maintain good health and prevent common lifestyle-related diseases