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Additional file 2 of PPFIA1 expression associates with poor response to endocrine treatment in luminal breast cancer
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Parameters used for MALT analysis from Variola virus genome sequenced from an eighteenth-century museum specimen supports the recent origin of smallpox
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Additional file 11 of Succession of physiological stages hallmarks the transcriptomic response of the fungus Aspergillus niger to lignocellulose
No full textMass-spectral data generated by metabolomics analysis of samples from dairy cattle
No full textSamples were collected from dairy cows to investigate how the metabolic fingerprint alters with lameness. Samples were analysed using LC-M
Mental health at work: a longitudinal exploration of line manager training provisions and impacts on productivity, individual and organizational outcomes. Data from TPI paper 1: Typology of employers offering line manager training for mental health
No full textThere are multiple papers associated with this sub-study: “Mental health at work: a longitudinal exploration of line manager training provisions and impacts on productivity, individual and organizational outcomes”. Each paper is associated with a separate dataset, which includes only the variables used within that specific paper. This metadata record refers only to the dataset associated with the first paper entitled: "Typology of employers offering line manager training for mental health"Mental ill health has a high economic impact on society and employers. National and international policy advocates line manager (LM) training in mental health as a key intervention, but little is known about employer training provisions. We aimed to explore the prevalence and characteristics of organizations that offer LM training in mental health. Secondary analysis was undertaken of existing longitudinal anonymised organizational-level survey data derived from computer-assisted telephone interview surveys collected in four waves (2020:1900 firms, 2021:1551, 2022:1904, 2023:1902) in England, before, during and after a global pandemic
Vaccine NMA data & syntax
No full textPsychological and behavioural factors influence the effectiveness of vaccines. This has led to interest in the potential for non-pharmacological treatments, which modify these factors, to enhance vaccine effectiveness. We conducted a systematic review and network meta-analysis (NMA) to examine the effects of non-pharmacological adjuvants on vaccine effectiveness, as measured by antibody responses to vaccination.
Electronic databases (EMBASE, Medline, PsychINFO, CINAHL) were searched from inception to 6th February 2018. This yielded 100 eligible papers, reporting 106 trials: 79 interventions associated with diet and/or nutrition; 12 physical activity interventions and 9 psychological interventions.
We observed that over half of all trials (k=58/106 trials) reported evidence of non-pharmacological interventions enhancing the antibody response to vaccination across one or more outcomes. The NMA considered the evidence for the effects of all intervention types compared with placebo on antibody titres (k=48 studies), seroconversion (k=25 studies) and seroprotection (k=23 studies) separately. The NMA provided weak evidence in support of nutritional formulae and probiotics in increasing antibody titres.
This literature provides early evidence of nutritional formulae and probiotic interventions being associated with enhanced antibody responses to vaccination. The absence of evidence for other treatments is likely to be the consequence of limited and unreliable evidence on these treatments