Indonesian Journal of Medicine (IJM)
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Effectiveness of Specific Training on Physical Functional Improvement and Walking Speed in Patients with Knee Osteoarthritis
Background: Osteoarthritis (OA) is a musculoskeletal disorder which is a progressive change in joints that is slow and intermittent, usually in the field there are exercises to strengthen muscles which are only supported by the agonist muscles while the antagonistic muscles also participate and even more dominant, the most approved intervention to be able to activate both muscles is a special task. The purpose of this study is to study whether there are functional requirements for specific tasks to improve the functioning and running of osteoarthritis patients.Subjects and Method: This study method uses the type of experimental research with a single case research method using A-B-A research design. The study was conducted in January 2020 located at the University of Muhammadiyah Surakarta. A patient with knee OA was selected using consecutive sampling. Functional ability and walking speed were tested by West Ontario and McMaster Osteoarthritis Index (WOMAC).Results: Specific training improved physical function and speed walking in patients with knee osteoarthritis. There was no effect of specific training on pain and stiffness.Conclusion: Task specific training improves functional ability and walking performance in aptient with knee osteoarthritis.Keywords: Osteoarthritis, task specific training, visual surface electromyograph, augmented feedback, functional ability.Correspondence: Suryo Saputra Perdana. Faculty of Health Sciences, Universitas Muhammadiyah Surakarta, Jl. Ahmad Yani, Tromol Pos 1, Pabelan Kartasura, Sukoharjo 57169, Central Java, Indonesia. Phone: +6281298563988. Email: [email protected] Journal of Medicine (2022), 07(01): 89-101https://doi.org/10.26911/theijmed.2022.07.01.10
Atypical Spinal Tuberculosis of Upper Thoracic Spine: A Rare Case Report
Background: Tuberculous infection is one of the most common pulmonary infection in developing countries, including Indonesia. Spinal tuberculosis is one of the most common extra¬pulmonary tuberculosis manifestation, accounting for 5% of all extrapulmonary spread, and 50% of all osteoarticular involvement. The aim of this study is to evaluate and how diagnosis and treatment to prevent over or under-diagnosis and explain about excellent management without any late complication further.Case Presentation: A 20-year-old male with a history of weakness of both of his leg for 20 days prior to admission. From these examinations, patient was then diagnosed with pathological fracture 2nd thoracic vertebral body suspected due to atypical spinal tuberculosis. Patient was then undergone surgical debridement, decompression, stabilization and fusion.Results: Patient was then undergone surgical debridement, decompression stabilization fusion. During the exposure at level C6 through Th4, no abscess was found. Transpedicular debridement at level Th2 was then done after the insertion of pedicle screws at level C6-Th1 and Th3-Th4, and again no abscess was present, however, a granulomatous mass was present on the location of 2nd thoracic vertebral body, located on the anterior right side of the spinal cord outside the dura mater.Conclusion: Atypical presentation of spinal tuberculosis with the sole clinical manifestation of neurological deficit below affected level. The definitive treatment such as surgical debridement, stabilization and fusion must be consider.Keywords: spinal, infection, tuberculosis, young patient.Correspondence: I Gusti Lanang Ngurah Agung Artha Wiguna. Division of Spine, Department of Orthopaedic & Traumatology, Prof. I.G.N.G Ngoerah Hospital, Faculty of Medicine, Udayana University, Bali, Indonesia. Email:[email protected]. Mobile: 0811388859.Indonesian Journal of Medicine (2022), 07(03): 289-297https://doi.org/10.26911/theijmed.2022.07.03.0
Effect of Kinesiotaping in Reducing Low Back Pain in Pregnant Women: A Meta-Analysis
Background: Pregnancy causes physiological changes that affect the musculoskeletal system and usually poses a risk of low back pain. This study aims to analyze the effect of kinesiotaping on reducing low back pain in pregnant women based on the results of a number of previous primary studies.Subjects and Method: This study uses a meta-analysis method with articles searched using the search keywords "Low back pain" OR "pelvic girdle pain" AND "pregnancy" OR "kinesiotaping" OR "kinesio tape" AND "pain reduction" OR "VAS" AND " Randomized Controlled Trial” OR “RCT” from PubMed, google scholar and science direct and processed using RevMan 5.3. The independent variable is kinesiotaping and the dependent variable is low back pain.Results: 9 RCT articles that fit into the inclusion criteria, with a total of 572 samples. Pregnant women with low back pain who received kinesiotaping had an average VAS score of 1.23 units lower than those without kinesiotaping, and the effect was statistically significant (SMD= -1.23; 95% CI -2.30 to -0.16; p= 0.02). In other words, kinesiotaping is effective in reducing low back pain in pregnant women.Conclusion: Kinesio Taping has an effect on reducing low back pain in pregnant women.Keywords: kinesiotaping, low back pain, pregnancy, visual analogue scaleCorrespondence: Atik Handariati. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. Email: [email protected]. Mobile: +6283895940042.Indonesian Journal of Medicine (2022), 07(02): 161-171https://doi.org/10.26911/theijmed.2022.07.02.05
Meta-Analysis the Efficacy of Turmeric (Curcuma domestica) in Reducing Pain in Patients of Knee Osteoarthritis
Background: Osteoarthritis (OA) of the knee joint has the highest prevalence among all types of rheumatic diseases. The most common symptom of knee OA is pain around the joint. Patients with OA require long treatment, especially using analgesic and anti-inflammatory drugs. Turmeric is efficacious as a pain reliever and anti-inflammatory. This study aims to estimate the magnitude of the effect of turmeric extract (Curcuma domestica) on pain in patients with knee OA compared to placebo and non-steroidal anti-inflammatory drugs (NSAIDs), based on the results of a number of previous similar studies.Subjects and Method: This study is a systematic review and meta-analysis with the following PICO, population: patients with knee OA. Intervention: turmeric extract. Comparison: placebo and NSAIDs. Outcome: pain reduction. The articles used in this study were obtained from three databases, namely Google Scholar, Pubmed, and Science Direct. Keywords to search for articles: “Knee Osteoarthritis” OR “Knee OA” AND “Curcuma longa” OR “Curcuma domestica” OR “Turmeric extract” AND “Placebo” OR “NSAID” AND “pain” OR “visual analogue scale” OR “ VASE". The articles included are full-text with RCT study designs from 2011 to 2021. The selection of articles is carried out using PRISMA flow diagrams. Articles were analyzed using the Review Manager 5.3 application.Results: A total of 15 RCT studies were selected for systematic review and meta-analysis. Data collected from 10 studies showed that patients with knee OA who received turmeric extract experienced 1.60 units lower joint pain than placebo (SMD= -1.60; 95% CI= -2.23 to -0.97; p<0.001). Data from 5 studies showed that patients with knee OA who received turmeric extract experienced 0.06 units higher joint pain than NSAIDs. The comparison between the turmeric extract group and the NSAID group did not show any significant difference (SMD= 0.06; 95% CI= -0.10 to -0.22; p= 0.490).Conclusion: Administration of turmeric extract was more effective than placebo and not inferior to non-steroidal anti-inflammatory drugs in reducing pain in patients with knee OA.Keywords: osteoarthritis, turmeric, painCorrespondence: Danang Ardiyanto. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: [email protected]. Mobile: 08122762579.Indonesian Journal of Medicine (2021), 06(04): 364-376https://doi.org/10.26911/theijmed.2021.06.04.0
Effect of Garlic Powder Supplementation on Total Cholesterol and Low Density Lipoprotein Level in Patient with Hypercholesterolemia: A Meta-Analysis
Background: Hypercholesterolemia is a risk factor for cardiovascular disease that can cause death and disability, so it must be managed properly. Garlic flour (GP) is one of the dosage forms of garlic that has the potential to reduce cholesterol. This study is a systematic review and meta-analysis that aims to determine the effectiveness of GP in reducing total cholesterol (TC) and low density lipoprotein (LDL).Subjects and Method: Search articles through the Pubmed database, Google scholar, Proquest, Springer link, and Science direct with the appropriate keywords. Population= patients with hypercholesterolemia. Intervention= GP. Comparison= placebo. Outcome= TC and LDL. Inclusion criteria included complete articles in English or Indonesian published from 2010-2022, Randomized Controlled Trial (RCT) design, subjects >18 years old with hypercholesterolemia, the study had a complete fat profile outcome, duration of intervention 2 weeks-12 months. The flow of article selection is based on the PRISMA flow diagram. Meta-analysis using RevMan 5.3 with effect size standardized mean difference (SMD) and Random Effect Model (REM) analysis model.Results: A total of 10 articles were eligible for a meta-analysis. The GP group had TC levels 1.49 units lower than the placebo group (SMD = -1.49; 95% CI = -1.95 to -0.55; p = 0.005) and LDL levels 0.68 units lower than the placebo group (SMD= -0.68; CI95). %= -1.08 to -0.27; p=0.001). Subgroup analysis based on the length of the intervention showed that administration of GP <12 weeks only significantly reduced TC while administration > 12 weeks significantly reduced TC and LDL.Conclusion: GP is effective in lowering TC and LDL especially at 12 weeks or more.Keywords: garlic powder, hypercholesterolemia, RCTCorrespondence: Zuraida Zulkarnain. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta, Central Java 57126. Mobile: 081393933862. Email: [email protected] Journal of Medicine (2022), 07(01): 102-114https://doi.org/10.26911/theijmed.2022.07.01.1
Reduction of Fructosamine Levels after Ramadan Fasting in Children with Type 1 Diabetes Mellitus
Background: Ramadan fasting is one religious challenge for children with type 1 diabetes mellitus (T1DM) which required specific management and strict monitoring. Fructosamine, which reflects glycemic control within 2-3 weeks, is an ideal parameter of glycemic control in Ramadan fasting. This study aimed to analyzed the effect of Ramadan fasting on fructosamine level of children with T1DM.Subjects and Method: This prospective cohort study included children aged under 18 years old diagnosed wit T1DM for >6 months at Dr. Soetomo Hospital, Surabaya, Indonesia in Ramadan 1438 H (May-June 2017). The independent variable from this study was Ramadhan fasting and the dependent variables were fructosamine and HbA1c. The sampling technique was total sampling. Forty-two children were included and devided into 27 children in the fasting and 15 children in the non-fasting group. Fructosamine and HbA1c levels were measured before, mid- and after Ramadan and the comparison between groups were analyzed using the independent T-test.Results: The mean age of all the subjects was 8.95 (SD=3.2) years old, 47.6% were males. The mean (SD) HbA1c level of all the subjects was 10.42 (1.16) %. There was a mild reduction of mean fructosamine level after Ramadan in the fasting group. There was no significat differece I fructsamie level before (Mean= 556.8; SD= 180.39; p= 0.620), mid (Mean= 568.07; SD= 175.37; p= 0.520), and after Ramadhan between groups (Mean= 539.41; SD= 173.04; p= 0.410) respectively. The average fructosamine levels after Ramadan was positively and strongly related to HbA1c (r=0.69; p<0.001). There was no case of severe hypoglycemia and diabetic ketoacidosis in both groups.Conclusion: There is a reduction of mean fructosamine level after Ramadan fasting in children with T1DM although it isn’t statistically significant.Keywords: type 1 diabetes, children, fasting, Ramadan, fructosamineCorrespondence: Nur Rochmah. Department of Child Health, Dr. Soetomo General Hospital/ Faculty of Medicine, Universitas Airlangga. Mayjend Prof. Dr. Moestopo No. 6-8, Surabaya, East Java, Indonesia, 60286. Number: +6281703501118. Email: [email protected] Journal of Medicine (2022), 07(02): 131-137https://doi.org/10.26911/theijmed.2022.07.02.0
Bilateral Pulmonary Arteriovenous Malformation in Female Patient Based on Computed Tomography Imaging: A Rare Case Report
Background: Pulmonary arteriovenous malformations (PAVMs) is an extremely rare vascular anomaly due to a direct connection between the pulmonary artery and pulmonary vein, potentially causing irreversible damages to the systemic circulation. This condition requires a prompt diagnostic approach to ensure early diagnosis and treatment.Case Report: A 53-year-old Indonesian female was referred to our department with unexplained dyspnoea and cyanosis. Physical examination revealed low oxygen saturation and remarkable finding on pulmonary auscultation. Further investigation revealed the findings suggesting PAVM based on contrast-enhanced chest computed tomography (CT) scan, with multiple nidus on bilateral lungs with feeder arteries from the pulmonary artery and draining veins in the pulmonary vein. Hence, this case emphasizes the rare finding of a female PAVMs patient with bilateral PAVMs.Conclusion: CT scan is a reliable and effective imaging approach to establish the diagnosis of PAVMs. This modality should be first considered to visualize PAVMs lesions, particularly in adult patients with unexplained dyspnoea and cyanosis.Keywords: arteriovenous malformations, CT scan, rare case, embolizationCorrespondence: Sony Sutrisno. Department of Radiology, Faculty of Medicine and Health Sciences, Krida Wacana Christian University, Jakarta, Indonesia. Email: [email protected]. Mobile: +62-8128-9290-414. Indonesian Journal of Medicine (2021), 06(04): 393-398https://doi.org/10.26911/theijmed.2021.06.04.0
Profile of Cognitive Impairement in Patients with Brain Tumors in Dr. Moewardi Hospital, Surakarta
Background: Brain tumor is a disease that is difficult to treat and causes high morbidity and morta¬lity. One of the clinical manifestations of brain tumors is cognitive impairment which is the most common neurological problem. The aim of this study is to determine the profile of cognitive impairment in patients with brain tumors.Subjects and Method: The design of this study was a retrospective cross-sectional using secondary data from the Neurology Polyclinic of RSUD Dr. Moewardi in January 2021-March 2022. The subject was diagnosed with a brain tumor based on anamnesis, physical examination, and neuroimaging. Cognitive impairment was inferred through the MoCA-Ina test. The analysis used was univariate descriptive analysis, independent T test, Mann-Whitney test, and Pearson correlation test.Results: There were 29 subjects with a mean MoCA-Ina score (17.97). Primary brain tumors (79.3%), more than metastatic tumors. The majority of patients were diagnosed with meningioma (55.2%). This study showed that there were differences in abstraction scores (p=0.015) and total MoCA-Ina scores (p=0.042) between patients with tumors located in the temporal lobe and non- temporal lobe; differences in abstraction scores (p=0.034) and orientation scores (p=0.042) between patients with supratentorial and infratentorial tumors; and differences in memory scores (p=0.028) between patients with and without radiation history. In addition, this study also found an association between the number of lobes affected by brain tumors with attention score (p=0.027; r=-0.409), abstraction score (p=0.004; r=-0.524), orientation score (p=0.021; r=-0.426), and the total score of MoCA-Ina (p=0.018, r=-0.435).Conclusion: There is an association between brain tumors and cognitive impairment which is concluded through the MoCA-Ina test. The clinical manifestations of cognitive impairment in the patient are in accordance with the neuroanatomical function of the brain affected by the lesion.Keywords: Cognitive, Tumor, MoCA-InaCorrespondence: Maria Yosita Ayu Hapsari. Department of Neurology, Faculty of Medicine, Universitas Sebelas Maret/ Moewardi Hospital, Indonesia. Email: [email protected]. Phone: 0813 3155 5412.Indonesian Journal of Medicine (2022), 07(02): 242-250https://doi.org/10.26911/theijmed.2022.07.02.1
Meta Analysis: Relationships of Risk Factors of Physical Activity and Obesity with Premenstrual Syndrome
Background: Premenstrual syndrome is actually experienced by almost all women wherever they are, but most teenagers think the symptoms they feel do not require further intervention or treatment. This study aims to analyze the relationship between physical activity and obesity with premenstrual syndrome based on the results of several previous similar primary studies.Subjects and Method: This study was conducted using a meta-analysis study with PICO as follows: P= women aged 17-50 years, I= high physical activity and obesity, C= low physical activity and not obesity, O= premenstrual syndrome. Article searches were conducted using electronic databases, namely Pubmed, Google Scholar, Springer Link, Clinical Key, and Proquest. Article searches were conducted using keywords and the Mesh method as follows "physical activity and obesity and premenstrual syndrome", "physical activity and obesity and premenstrual syndrome and adjusted Odds Ratio", "physical activity and obesity and premenstrual syndrome and study cross sectional", " physical activity or obesity or premenstrual syndrome", "physical activity or obesity or premenstrual syndrome or adjusted odds ratio", "physical activity or obesity or premenstrual syndrome or study cross sectional". Articles were analyzed using the Review Manager 5.3 application.Results There are 13 articles from the continents of Africa, Asia, South America, and Europe which include Japan, Palestine, Arabia, Iran, Lebanon, Egypt, Brazil, and Turkey from 2000-2022 which were analyzed using PRISMA flow diagrams. Research studies show that women who do a lot of physical activity have a risk of developing premenstrual syndrome as much as 0.80 times compared to women who do less physical activity (aOR= 0.80; 95% CI = 0.51 to 1.25; p<0.001 ); and obese women had 1.03 times the risk of developing premenstrual syndrome compared with non-obese women (aOR = 1.03; 95% CI = 0.95 to 1.11; p = 0.49).Conclusion: Physical activity can reduce the risk of premenstrual syndrome and obesity can increase the risk of premenstrual syndrome.Keywords: physical activity, obesity, premenstrual syndromeCorrespondence: Erza Husna. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36 A, Surakarta 57126, Central Java, Indonesia. Email: [email protected]. Mobile: +6285747580999.Indonesian Journal of Medicine (2022), 07(02): 219-231https://doi.org/10.26911/theijmed.2022.07.02.1
Meta-Analysis Predictors of Sufficient Pain Management among Children at Pre-hospital Medical Service
Background: Safely treating pain in children is a critical but challenging task for emergency medical teams. Few studies have focused on pain management guidelines at the hospital or department level. This study aimed to examine predictors of good pain management in children in prehospital health services.Subject and Method: This research is a systematic review and meta-analysis study using PRISMA diagrams. The article search was conducted based on the PICO Model eligibility criteria. P: children with pre-hospital acute Pain. I: analgesic administration and male. C: no analgesic administration, and female. O: pain reduction. The articles used were from 5 databases: EBSCO, Pubmed, ProQuest, Scopus, and Science Direct. The search keywords for articles were as follows “pain management” OR “pain reduction” AND “predictors” AND “pre-hospital care” AND “children”. The inclusion criteria in this study include full-text articles with observational study designs, full-text available articles, the relationship size used is the adjusted Odds Ratio, articles published in the 2010-2022 range, and the research outcome is sufficient pain management or efficient pain reduction. Articles were analyzed using the Review Manager 5.3 application.Results: There are 8 articles in this study, 2 from Australia, 1 from the United States, 1 from Switzerland, and 4 articles from the United Kingdom. The article was analyzed using the PRISMA flow diagram. The study results show that analgesic administration has increased the odds of 3.36 times greater for pain reduction than without analgesic administration. This result was statistically significant (aOR= 3.36; 95% CI = 1.94 to 5.82; p<0.001). However, no significant results from the gender that showed there is no different between male and female patients for pain reduction (aOR= 1.12; 95% CI= 0.98 to 1.27; p= 0.100).Conclusion: Analgesic administration is sufficient pain management for children with acute Pain in pre-hospital medical care.Keywords: children, pre-hospital care, pain management, predictorsCorrespondence: Arief Wahyudi Jadmiko. Nursing Department, Faculty of Health, Universitas Pembangunan Nasional Veteran Jakarta. Jl. Raya Limo Depok 16515 West Java, Indonesia. Email: [email protected]. Mobile: 085647213628.Indonesian Journal of Medicine (2022), 07(04): 360-370https://doi.org/10.26911/theijmed.2022.07.04.01