Indonesian Journal of Medicine (IJM)
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Effect of Date Palm (Phoenix dactylifera) Fruits Consumption on Birth Delivery Outcome: Meta-Analysis
Get PDFBackground: The choice of cesarean section continues to increase in the world and is expected to continue to increase over the coming decades, which is almost a third of all deliveries in 2030. The benefits of dates for improving labor processes are considered to increase vaginal deliveries and also reduce the frequency of cesarean sections with the aim of reducing bigger complications. This study aims to analyze and estimate the influence of the consumption of dates on labor outcomes.Subjects and Method: This study is a systematic review and meta-analysis with PICO, P: Pregnant women, I: consumption of dates, C: No consumption dates, O: Bishop's score, length of labor, and postpartum hemorrhage. Data collection was obtained from databases, namely: PubMed, Science Direct, Springer Link, and Google Scholar. Keywords used “date fruit” OR “date palm” OR “phoenix dactylifera” AND “labor” AND “delivery”, AND “oxytocin” AND “hemorrhage”. The inclusion criteria used were full papers in English with the design of randomized controlled trials in 20002022. This study was analyzed using RevMan 5.3 software.Results: Meta-analysis was conducted on 4 primary studies from several countries such as Iran, Malaysia, and Saudi Arabia with a sample size of 603 pregnant women. The meta-analysis concluded that there was an effect of date consumption on cervical dilatation upon admission to the hospital (SMD= 0.73; CI 95%= 0.09 to 1.38; p=0.030). Consumption of dates also has an effect on the duration of active 1st stage labor (SMD= 0.46; CI 95%= 0.82 to 0.09; p= 0.010). Consumption of dates has a weak effect on the length of stage II labor (SMD= 0.05; 95% CI= 0.88 to 0.78; p= 0.910). In addition, the consumption of dates also has a weak effect on the length of stage III labor (SMD=0.16; CI95%=0.46 to 0.79; p=0.610).Conclusion: Consumption of dates has an influence on labor outcomes.Keywords: phoenix dactylifera, dates, labor, postpartum hemorrhage, Bishop scoreCorrespondence: Ratna Purwani Siwi. Masters Program in Public Health, Universitas Sebelas Maret. Jalan Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. Email: [email protected]. Mobile: 085602389598.Indonesian Journal of Medicine (2023), 08(01): 79-91https://doi.org/10.26911/theijmed.2023.08.01.08
“TRISNA” Conceptual Model and Spiritual Approach to Build Body Image, Self-Esteem, and Quality of Life in Cervical Cancer Patients at Dr. Moewardi Hospital, Surakarta, Indonesia
Get PDFBackground: The problems of cervical cancer patient’s psychological response to advanced cancer are acute crisis, struggle, anxiety, and sadness, which will interfere with their life, especially sexual relations with their partners. Sexual relations in the Javanese view are a noble, sacred bond and have the function to maintain harmony. The spiritual approach and "TRISNA" which contains the principles of Javanese teachings about sincerity should be applied by cervical cancer patients and their sexual partners. This study aimed to determine the effect of palliative sexuality treatment with a "TRISNA" and spiritual approach to body image, self-esteem, and quality of life in cervical cancer patients at Moewardi Hospital Surakarta.Subjects and Method: This study was a quasi-experimental design using 138 samples divided into three groups, namely the TRISNA, Spiritual, and control groups with a pre-test-post-test control group design conducted at Dr. Moewardi Hospital Surakarta, Central Java, in May to August 2019. The dependent variable in this study is the body image scale, self-esteem, and quality of life. The independent variables in this study are the TRISNA and spiritual approaches. The instruments used are the body image scale, self-esteem scale, and the European Organization for Research and Treatment of Cancer (EORTC) QOQ-CX24. Statistical analysis using t-test with SPSS 13 application software.Results: The results showed that sexuality with the TRISNA and spiritual approaches can improve body image (F= 137.67), self-esteem (F= 241.05), and quality of life (F= 76.95) of cervical cancer patients with a significant value for each group (p≤0.001).Conclusion: Sexuality with TRISNA's approach is the most influential in body image, self-esteem, and quality of life in cervical cancer patients in cervical patients Moewardi Hospital Surakarta.Keywords: body image scale, self-esteem, quality of life, sexuality, spiritualCorrespondence: Rita Benya Adriani, Ministry of Health of Surakarta, Health Polytechnics Surakarta, Letjend Sutoyo Street, Mojosongo, Surakarta 57127, Central Java, Indonesia. Email: [email protected]. Mobile +628122617033.Indonesian Journal of Medicine (2023), 08(01): 37-46https://doi.org/10.26911/theijmed.2023.08.01.0
Meta-Analysis: Application of Theory of Planned Behavior on Acupuncture Therapy Utilization in Cancer Patients with Pain
No full textBackground: Cancer is a health disorder caused by the formation of abnormal cells that grow past the normal cell cycle limit and can attack and spread to other parts of the body. In the Theory of Planned Behavior, one's behavior can be influenced by three main aspects, including attitudes, subjective norms, and behavioral control. The purpose of this study was to estimate perceived benefits, perceived barriers, and subjective norms regarding the use of acupuncture therapy in cancer patients with pain.
Subjects and Method: This was a systematic review and meta-analysis. This study uses the PICO model. The meta-analytic study was carried out by searching for articles from databases in electronic form using Google schoolar, PubMed, and Elsevier. Article searches were conducted from 05 February to 10 March 2023. The keywords used were “Theory of Planned Behavior” OR “TPB” AND “Acupuncture” OR “Complemantary Alternative Medicine” AND “Cancer” OR “Pain” AND “Cancer Pain” OR “Cross-Sectional”. The inclusion criteria for this study were complete articles using cross-sectional research, published years from 2007-2022. Analysis of the articles in this study used RevMan 5.3 software.
Results: 8 cross sectional studies from North United States and Asia (Korea and Malaysia) were selected for meta-analysis. High perceived benefit (aOR= 1.20; 95% CI= 1.09 to 1.33; p<0.001) and strong subjective norm (aOR= 1.05; 95% CI= 1.01 to 1.08; p= 0.005) increased acupuncture utilization to reduce pain. High perceived barrier reduced acupuncture utilization (aOR= 0.94; 95% CI= 0.91 to 0.97; p < 0.001).
Conclusion: High perceived benefit and strong subjective norm increase the use of acupuncture. Strong perceived barrier reduces the use of acupuncture.
Keywords: Theory of Planned Behavior, cancer patients with pain, acupuncture therap
Description of Hematological Parameters and Severity Levels of COVID-19 Patients and Disease Progression at Royal Prima Hospital, Medan, North Sumatera, Indonesia
Get PDFBackground: The severity of COVID-19 can be evaluated by checking several routine hematological parameters. Routine hematology examinations have an important role in early detection, diagnosis, disease management and disease progression. This study aims to determine the relationship between hematological parameters and disease progression and severity in COVID-19 patients.
Subjects and Method: This was a cross sectional study conducted at Royal Prima Hospital, Medan, North Sumatera, Indonesia, from January to February 2022. A total of 93 patients who had confirmed COVID-19 were selected using a simple random sampling technique according to the inclusion and exclusion criteria. The research was The dependent variables of this research were disease progression and severity of COVID-19 patients. The independent variables are hematological parameters based on hospital medical record data. Data analysis used the Chi-Square test and logistic regression.
Results: 75 people (80.6%) COVID-19 sufferers had severe disease. NLR and D-dimer levels were significantly related to disease progression in COVID-19 sufferers (p<0.05). Leukocyte, lymphocyte, NLR, CRP, D-dimer levels are related to the severity of COVID-19 sufferers (p<0.05). Leukocyte levels have the strongest relationship with the severity of COVID-19 with an OR value of 1.798.
Conclusion: NLR and D-dimer levels are significantly related to disease progression and leukocyte. Lymphocyte, NLR, CRP, D-dimer levels are related to the severity of COVID-19 sufferers
The Effect of High Knowledge on Diabetes Type 2 and Strong Belief in Medicine with Non-Adherence of Anti Diabetic Medication: A Meta-Analysis
Get PDFBackground: By 2045, the number of people with diabetes mellitus (DM) was expected to increase from 424.9 million in 2017. Healthcare professionals have had a difficult time managing diabetes because of nonadherence to therapy. Additionally, the efforts made to clarify and enhance patient adherence to their medication are not always successful. This study investigated the factors such as high knowledge on diabetes type 2 and strong belief in medicine that lead to medication non-adherence in adults.Subjects and Method: This article was a systematic review and meta-analysis study conducted by searching for articles from online databases such as EBSCO, ProQuest, and PubMed. Populations: adults with diabetes mellitus; Intervention: a strong belief in anti-diabetic medication and high knowledge of diabetes mellitus; Comparison: a weak belief or none in anti-diabetic medication and little knowledge of diabetes mellitus; Outcome: non-adherence of anti-diabetic medication. The independen variables is strong belief and high knowledge, the dependen variable is non-adherence to anti-diabetic medication. The inclusion criteria for this study were full articles using a cross-sectional study, with the publication year until 2022. We conduct the analysis using RevMan 5.3 software.Results: A total of 6 articles reviewed in the meta-analysis (consisted 4 articles in each variables), from countries: Ethiopia, Australia, Uganda, Iran, Palestine and China, showed that respondents with strong belief in anti-diabetic medicines (aOR= 0.66; 95% CI= 0.48 to 0.90; p= 0.008) and high knowledge of diabetes mellitus (aOR= 0.85; 95% CI= 0.79 to 0.93; p= 0.0005) had lower level of non-adherence to anti-diabetic medication.Conclusion: A strong belief in anti-diabetic medicines and high knowledge of diabetes mellitus can lower non-adherence to anti-diabetic medication.Keywords: diabetes mellitus type 2, medication adherence, predictorsCorrespondence: Sri Iswahyuni. Study Program of Nursing, School of Health Sciences Mamba’ul ‘Ulum Surakarta. Jl. Ring Road 03, Surakarta 57127, Jawa Tengah. Email: [email protected]. Mobile: +62 815-6720-715.Indonesian Journal of Medicine (2022), 07(02): 150-160https://doi.org/10.26911/theijmed.2022.07.02.04
Mortality of TB-HIV Co-Infection Patients Based on CD4 Level: Meta-Analysis
Get PDFBackground: Tuberculosis (TB) is the most common cause of death in patients with the Human Immunodeficiency Virus (HIV). Understanding CD4 as a predictor of mortality from TBHIV coinfection is critical to improving disease management and minimizing mortality. This study aims to examine the mortality risk of TBHIV-coinfected patients based on CD4 values.Subjects and Method: Metaanalysis was performed according to the PRISMA flow chart and the PICO model (Population: TBHIV coinfected patients, Intervention: CD4 value <200 cells/µL, Comparison: CD4≥200 cells/µL, Outcome: mortality). The databases used are Google Scholar, PubMed, Scopus, Proquest, and Science Direct. Keywords used (coinfection OR "mixed infection") AND (HIV OR "Human Immunodeficiency Virus") AND (TB OR “tuberculosis”) AND ("CD4 count" OR "T4 lymphocyte") AND “mortality”. The inclusion criteria were full-text articles with cohort studies published in 20122022, articles in English, and multivariate analysis using the adjusted hazard ratio. Analysis was performed with Revman 5.3.Results: 17 articles with cohort design originating from Ethiopia, Khayelitsha, Kenya, Cape Town, Uganda, Brazil, Suriname, Sao Paulo, Guinea Bissau, Myanmar, Durban, Ireland, China, and multicountry studies between Europe and Latin America totaling 24,514 research sample. A meta-analysis of 10 study cohorts concluded that CD4<200 cells/µL had a 2.00 times risk of mortality compared with CD4 values ≥200 cells/µL (aHR=2.00; 95% CI 1.44 to 2.78; p<0.001). A meta-analysis of 7 study cohorts concluded that CD4<100 cells/µL had a 2.40 time risk of mortality compared with CD4 values≥200 cells/µL (aHR=2.40; 95% CI 1.61 to 3.57; p<0.001). A meta-analysis of 7 study cohorts concluded that CD4<50 cells/µL had a 3.12 times risk of mortality compared with CD4 values≥200 cells/μL (aHR=3.12; 95% CI 1.51 to 6.46; p<0.001).Conclusion: Decreased CD4 values increase the risk of mortality.Keywords: tuberculosis, HIV, CD4, mortality, meta-analysisCorrespondence: Victoria Husadani Permata Sari. Master’s Program in Public Health, Universitas Sebelas Maret. Jl. Ir Sutami 36A, Surakarta 57126, Jawa Tengah. Email: [email protected]. Mobile: 081393539020.Indonesian Journal of Medicine (2022), 07(04): 456470https://doi.org/10.26911/theijmed.2022.07.04.11
Neurological Abnormalities in Congenital Rubella Syndrome and Possible Pathophysiology
Get PDFBackground: Congenital rubella syndrome is a disease that is a relative severe health problem because it causes multiorgan disability. The purpose of the study was to describe the neurological abnormallities that occur in congenital rubella syndrome and its pathophysiology.Case Presentation: A descriptive study with the subjects of the study of infants and children with congenital rubella syndrome found in the private practice of pediatricians for 10 years aged 15 years with the most complaints of developmental and growth delays, recurrent seizures and behavioral disorders. most are first children with mothers without Measles, Mumps, and Rubella (MMR) vaccination. Inclusion criteria: infants and children with clinical manifestations of at least 2 of all major clinical signs (hearing loss, congenital cataracts and congenital heart defects) accompanied by evidence of infection in the form of rubellaspecific serum IgM and a history of the mother experiencing infection during pregnancy as evidenced by IgG results and or IgM rubella antibodies.Results: 13 cases were obtained, 92.3% of the case population with multiorgan disability and only 1 case (7.69%) with neurological disorders alone. 84.6% of cases of neurological disability occurred as a result of infection in the 1st trimester.Conclusion: Neurological abnormalities were acquired in the entire study population and were mostly due to infections in the 1st trimester of pregnancy.Keywords: neurological abnormalities, congenital rubella syndrome.Correspondence: Erny. Pediatric Department Medical Faculty Wijayakusuma University. Jl. Dukuh Kupang XXV no 54 Surabaya, East Java, Indonesia. Email: [email protected]. Mobile: 0818381740.Indonesian Journal of Medicine (2022), 07(04): 449-455https://doi.org/10.26911/theijmed.2022.07.04.1
Meta-Analysis of the Role of Varenicline in Smoking Cessation
Get PDFBackground: Smoking is the leading cause of premature death in both developed and developing countries. Smoking cessation efforts can be classified into pharmacological and therapeutic strategies. Varencline is the latest discovery for pharmacological therapy for smoking cessation programs. This study aims to determine the role of varenicline on smoking cessation efforts.Subjects and Method: This was a systematic review and meta-analysis conducted using PRISMA flow diagrams. Search articles through journal databases including: Google Scholar, MEDLINE/ PubMed, Science Direct, Scopus, and Spinger Link by selecting articles published in 2011-2021. The keywords used are “varenicline” OR “pharmacotherapy” AND tobacco OR smoke OR smoked OR smoker AND “smoking cessation”. The research instrument used to assess smoking cessation efforts was the Fagerstrom Test for Nicotine Dependence (FTND). The inclusion criteria were full paper articles with Randomized Controlled Trial (RCT) research methods, the relationship measure used was Mean SD, the intervention given was varenicline, the research subjects were adult smokers who wanted to quit smoking. Eligible articles were analyzed using the Revman 5.3 application.Results: Meta-analysis of 9 articles showed results (SMD -0.11; 95% CI = -0.17 to -0.05; p<0.001).Conclusion: Varenicline has a statistically significant effect in reducing the frequency of smoking per day.Keywords: Varenicline, smoking cessation, quitting smokingCorrespondence: Muhamad Zainul Lafif. Masters Program in Public Health. Universitas Sebelas Maret, Jl.Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. Email: [email protected]. Mobile: 082137179433.Indonesian Journal of Medicine (2021), 06(04): 354-363https://doi.org/10.26911/theijmed.2021.06.04.01
Meta Analysis the Effect of Acupunctur Therapy and Ultrasound Therapy to Reduce Pain Caused by Carpal Tunnel Syndrome
Get PDFBackground: Carpal tunnel syndrome is a condition of health problems in the form of pain, numbness, and tingling that occurs in a person's hands. This sensation can be felt in the thumb, index finger, middle finger, and 1/2 ring finger on the radial side, this occurs when the median nerve that passes through the carpal tunnel at the wrist is compressed or compressed. This study aims to estimate the effect of acupuncture therapy and ultrasound therapy on reducing pain in carpal tunnel syndrome cases.Subjects and Method: This was a systematic review and meta-analysis conducted using PRISMA flow diagrams. Article searches through journal databases include: PubMed, Science Direct, Scopus, Google Scholar, Springer Link, Hindawi, BMC. The PICOs of this study were, Population: carpal tunnel syndrome sufferers, Intervention: acupuncture therapy and ultrasound therapy, Comparison: no acupuncture and ultrasound therapy, Outcome: pain reduction. Using search keywords: (“acupuncture” OR “acupuncture therapy”) AND (“carpal tunnel syndrome” OR “cts”) AND (“ultrasound” OR “ultrasound therapy”) AND (“randomized controlled trial”) AND (“ acupuncture for carpal tunnel syndrome”) AND (“ultrasound for carpal tunnel syndrome”). Inclusion criteria were full paper articles with Randomized Controlled Trial (RCT) research method, the relationship measure used was Mean SD, the intervention given was acupuncture and ultrasound, study subjects were aged 18-85 years. Eligible articles were analyzed using the Revman 5.3 app.Results: Meta-analysis of 16 articles showed acupuncture treatment outcome of -0.34 units compared with other interventions or no intervention (SMD -0.34; 95% CI= -0.83 to 0.16; p=0.180), I2=78%, and treatment outcome. ultrasound as much as -0.76 units compared with other interventions or no intervention, and statistically significant value (SMD -0.76; 95% CI= -1.37 to -0.16; p=0.001), I2= 92%.Conclusion: Acupuncture therapy and ultrasound therapy have an effect on reducing pain in cases of carpal tunnel syndrome.Keywords: Acupuncture, ultrasound, carpal tunnel syndromeCorrespondence: Afifah Noer. Masters Program in Public Health. Universitas Sebelas Maret, Jl.Ir. Sutami 36A, Surakarta 57126, Jawa Tengah, Indonesia. Email: [email protected]. Mobile: 085601564681.Indonesian Journal of Medicine (2021), 06(04): 399-411https://doi.org/10.26911/theijmed.2021.06.04.0
Effect of Core Stability Exercise in Preventing Diastasis Recti Abdominis among Normal Birth Delivery of Postpartum Mothers: Meta-Analysis
Get PDFBackground: Diastasis Recti Abdominis (DRA) is a separation that occurs in the abdominal muscles, namely between the two rectus abdominis muscles. This separation is precisely in the linea alba which is the midline of the abdomen. DRA is characterized by two things, namely the widening of the inter-recti distance (IRD) and the appearance of a bulge in the abdomen. This is due to stretching and weakness of the linea alba. This study aims to analyze the effect of core stability exercise on reducing diastasis recti abdominis in normal postpartum mothers based on the results of a number of previous primary studies.Subjects and Method: This study uses a meta-analysis method with articles searched using the search keywords "Core stability exercise" AND "diastasis recti abdominis" OR "normal post partum" OR "caliper" OR "ultrasonography" OR "Randomized Controlled Trial" OR "RCT" from PubMed, Google Scholar and Scopus and processed using RevMan 5.3.Results: 9 RCT articles that fit into the inclusion criteria, with a total of 319 samples. Normal postpartum mothers with diastasis recti abdominis who received core stability exercise had an average caliper score of 4.71 units lower than those without core stability exercise, and the effect was statistically significant (SMD= -4.71; 95% CI -8.05 to -1.37; p= 0.060). Normal postpartum mothers with diastasis recti abdominis who received core stability exercise had an average ultrasound score of 0.80 units lower than those without core stability exercise, and the effect was statistically significant (SMD= -0.80; 95% CI -1.62 to 0.02; p= 0.060). In other words, core stability exercise is effective in reducing diastasis recti abdominis in normal postpartum mothers.Conclusion: Core stability exercise has an effect on reducing diastasis recti abdominis in mothers after normal delivery.Keywords: post partum, diastasis recti abdominis, core stability exercise, calipers, ultrasoundCorrespondence: Feny Oktaviyani. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. Email: [email protected]. Mobile: +6281312500575.Indonesian Journal of Medicine (2022), 07(02): 188-199https://doi.org/10.26911/theijmed.2022.07.02.0