International Journal of Agricultural and Life sciences (Skyfox Publishing Group)
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Anti-microbial Perspective of a Chalcone, (E)-1-(1-methoxy-9H-carbazol-3-yl)-3-(4-(methylsulfonyl) phenyl)prop-2-en-1-one: Fabrication of a Hybrid by Unification of a Natural Product with a Synthetic Component
Full text linkMurraya koenigii L. has been explored exhaustively and is known to possess more than 20 different carbazole-based alkaloids having multifarious therapeutic perception of this class of alkaloids, murrayanine is the highest explored alkaloid and is known to have (ethno)-pharmacological perspectives of purgative, astringent, febrifuge, anti-helminthic, anti-oxidant, anti-ulcerogenic, immunomodulation, etc. As murrayanine possess multiple sites for substituting wide-range of electron-donating / -withdrawing groups by semi-synthetic approach, in the present research, a chalcone; (E)-1-(1-methoxy-9H-carbazol-3-yl)-3-(4-(methylsulfonyl)phenyl)prop-2-en-1-one was fabricated rationally by incorporating a natural portion (murrayanine) in the A-ring and a synthetic component (4-methylsulfonyl group) in the B-ring and screened against two bacterial species (Escherichia coli and Staphylococcus aureus) and two fungal species (Candida albicans and Aspergillus niger). The rationally designed chalcone demonstrated noteworthy anti-microbial activity. The fabricated chalcone was observed to be a better anti-bacterial agent as compared to its anti-fungal potentials. As compared to the standard drugs, the experimental molecule does hold well against pathogenic challenges. The present research therefore opened new avenues of judiciously developing a natural scaffold having an active methylsulfonyl group, which will inspire life science researchers across the globe in developing inhibitors with pronounced biological activity as compared with the parent compounds
Evaluation of Bioactive Compounds in Nutrition Physiology
Full text linkMany peptides released from animal or plant proteins in vitro or in vivo have therapeutic functions in humans beyond bioactivity and adequate nutrition. Different health effects have been attributed to foodborne peptides, including antimicrobial properties, blood pressure lowering (ACE inhibitor) effects, cholesterol lowering ability, antithrombotic and antioxidant activities, increased mineral absorption, immunomodulatory effects and opioid activities. For this reason, nutritional counseling practices deal with these issues. Specific protein fractions with therapeutic effects on body function and health are termed biological peptides and have been shown to have a direct positive effect on health. Angiotensin I-converting enzyme (ACE) is a carboxy-dipeptidyl metallopeptidase associated with the renin angiotensin system that regulates the production of angiotensin II from vasoconstrictor angiotensin-II and peripheral blood pressure that catalyzes the inactivation of vasodilator bradykinin. For this reason, the ACE inhibitor substance in the diet may inhibit hypertension by inhibiting the renin-angiotensin system. Milk proteins are now the main source of bioactive peptides. Such peptides are seen as natural and non-effective alternatives to drugs in the treatment of hypertension. The natural consumption of biological peptides will not be expected to cause side effects of synthetically produced drugs used to control hypertension. Therefore, it can be used as a powerful functional food additive and the ACE inhibitor is a natural and healthy alternative to drugs
Evaluation of Sous-Vide Technology in Gastronomy
Full text linkSous vide is cooked under control by applying a certain temperature (65-96 oC) / time after vacuuming in the package of the food which is formed alone or with other auxiliary products (sauce-spices) and stored under cold conditions (1-4 oC) by rapidly reducing the temperature after heat application This process is also known as lapping, vacuum cooking, vacuum packed cooking with vacuum pack or baking-cooling with vacuum packaged. In the products prepared by this technology, the blocking effect provided by oxidative and aerobic bacteria development through vacuum packaging combines with microbial protection effect provided by pasteurization; Thanks to the applied cold chain, a long and safe shelf life is provided and consumed. Food can be made reliable by pasteurizing at low temperatures, and even safely consumed without cracking and crunchy foods. In addition to all these advantages, sous vide technology also has some disadvantages. When the investigations are examined, it has been concluded that the research on sous vide technology\u27s reliability in terms of health should be intensified
A Study on the Shelf life of the Spent Hen Meat Puffed Product (SHPP) Stored at Ambient Temperature
Full text linkHot extruded spent hen meat puffed products (SHPP) are made of spent hen meat mixed with flours and additives subjected to a maturing and extrusion process. This study was undertaken to evaluate the hygienic quality, the organoleptic characteristics, physico-chemical, proximate and microbial status during shelf life of SHPP in ambient temperature. Growth models, developed and validated on hot extruded spent hen meat puffed products (SHPP) were used to predict the growth of microorganisms. Temperature data were obtained from retail and home refrigerators. Shelf life was greatly influenced by storage temperature, but initial microbial load had a smaller effect. The expiration date of hot extruded spent hen meat puffed products must be based only on the growth of the spoilage microorganisms. Only when product contamination with bacteria cell concentrations is high, the product fraction poses health risks for consumers. Sensitivity analysis confirmed that storage temperature and temperature variability were the most important factors for the duration of shelf life
Solvent Extraction and Chemical Characterization of Papaya Seeds Oil
Full text linkPapaya (carica papaya L.) is a plant that grows wild in many parts of the tropics. The seeds of papaya fruits are generally discarded. However, in order to make a more efficient use of papaya, it is worth investigating the use of the seeds as a source of oil. A compound present in crushed papaya seeds is believed to have activity against helminthes intestinal parasites, benzyl isothiocynate has shown to have an effect on vascular contraction using a canine carotid artery in vitro model. The characteristic of seed oil was studied. Percent seed oil was recorded 30.1 and chemical composition of papaya seed was found to be protein (28.1%), Ash (8.2%), Crude fiber (19.1%) and total carbohydrate (25.6%). Papaya seed oil utilized in high amounts could lead to reduced risk of coronary heart disease. In addition, high oleic oil has sufficient stability to be used in demanding applications such as frying, bakery, crackers, cereal dried fruit, and spray oil for snacks. Papaya seed oil can be considered as high oleic and hence viewed as a healthy alternative to many other vegetable oils. Thus, it can be concluded that the seed can be utilized for extraction of oil which has various health benefits with respect to essential fatty acids. Mass production of the Oil will accelerate industrialization while promoting sustainable economic growth hence enhancing improved health and livelihood which is in line with the tenets of vision 2030 and the health-related Sustainable Development Goal
Evaluate the antimicrobial activity of Biosurfactant against ESBL producing bacterial isolates
Full text linkIn this present study, the biosurfactant producing ability of the microorganisms isolated from the soil samples was investigated by blue agar plate, oil spreading test and emulsification index. Among the 15 of them, the best isolate was identified as B.cereus based on microscopic and biochemical analysis. Our aim of the present study was to evaluate the antimicrobial activity of biosurfactant against ESBL producing P.aeruginosa isolates. Susceptibility tests were performed by the agar well diffusion method. Among the 5 ESBL isolates, 3 of them were inhibited by biosurfactant. The zone of inhibition ranged from 12 mm to 22 mm and MIC was 10mg/ml. This effect is comparable to antibiotics and therefore the future use of this biosurfactant as broad spectrum antibiotics are highly promising
Nutritional significance of cereals and legumes based food mix- A review
Full text linkTertiary processed foods are commercially formulated foods designed for the ease of consumption. These foods are mainly formulated using the refined flour which are lacking in one or more nutrients. Whole cereals and legumes found to possess immense nutritional potentials which could complement one another if accurately processed and combined. Therefore, it is essential to formulate composite blends and carry out scientific research to ascertain the nutritive adequacy of the cereal and legumes for possible use as tertiary foods. The present study is therefore a part of an exploratory work towards this goal. The study emphasis on formulation of tertiary processed foods with application of processing and drying methods using multicereals and legume combination. Successful utilization of cereals and legumes with added functionality in snack food sector will definitely open up new dimensions to the food industries
Food based phytochemical luteolin their derivatives, sources and medicinal benefits
No full textLuteolin is a type of flavonoid and a 38, 48, 5, 7-tetra hydroxyl flavone with a yellow crystalline appearance. Luteolin is widely present in different plant families such as, Lamiacea, Arecaceae, Brassicaceae, Campanulaceae, Asteraceae, Resedaceae and Scrophulariaceae. Luteolin mostly found in edible plants and most important food based phytochemical. Dietary sources of luteolin such as, celery, peppers, carrots, peppermint, olive oil, thyme, oregano and rosemary, etc. On the base of luteolin content among other sources oregano is the better source with 1028.75mg/100g contents. Flavonoids are important component of plants, and widely used in traditional medicine to cure the different type of diseases. Luteolin has different health benefits such as, anti-inflammatory, sun protectant, anti-oxidant, improve heart function, neurological impairments, anti-cancer and many more. Luteolin has many possible mechanisms involved in different biological activities such as, stabilization of p53, modulation of ROS levels, and reduction of NF- kappaB, reduction of AP-1 activity and inhibition of PI3K
Quality evaluation of soy milk ice cream prepared with ipomoea batatas starch and meteroxylon sagu powder as stabilizing agent
Full text linkStabilizers are used in ice cream preparation for viscosity, air incorporation, melt down and texture improvement to attain attractive end product. Soybeans were used to produce soy milk. Soy milk used as a milk replacer due to its some important health aspects such protein, vitamin C, isoflavones, dietary fiber, omega-3-fatty acid and oligosaccharides. Starch was extracted form Ipomoea Batatas. Meteroxylon Sagu powder and Ipomoea Batatas starch analyzed against some quality characteristics such as pH, swelling power and solubility, water holding capacity, moisture, ash protein and viscosity. Ice cream was prepared by using soy milk with different concentration such as 0.25, 0.5 and 0.75% of starch and powder. Commercially used stabilizing agent Cremodan was kept as reference standard. Prepared ice cream mix was analyzed against some physicochemical and sensory parameters. Ice cream sample that contain ipomoea batatas starch 0.75% showed significant (P<0.05) outcomes against overrun, standup time, viscosity and melt-ability. Soy milk ice cream development with natural stabilizers such as starches can be cost effective and provide more health benefits
In-vitro antioxidant and GC-MS analysis ethanolic extract of poly herbal drug
Full text linkAntioxidants play an important role in inhibiting and scavenging free radicals, thus providing protection to human against infections and degenerative diseases. Current research is now directed towards natural antioxidants originated from plants due to safe therapeutics. Poly herbal drugs is used in Indian traditional medicine for a wide range of various ailments. To understand the mechanism of pharmacological actions, antioxidant properties of the Poly herbal drugs extract were tested using standard in vitro models. The ethanolic extract of Poly herbal drugs exhibited strong scavenging effect on superoxide, nitric oxide radical and reducing power radical scavenging assay. The free radical scavenging effect of Poly herbal drugs extract was comparable with that of the reference antioxidants. The data obtained in the present study suggests that the extract of Poly herbal drugs have potent Invitro antioxidant and Anti Diabetic activity against free radicals, prevent oxidative damage to major biomolecules and afford significant protection against oxidative damage