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Data to support study of The Number and Shape of Lattice Solvent Molecules Controls Spin-Crossover in an Isomorphous Series of Crystalline Solvate Salts
Get PDFCrystals of [FeL2][BF4]2·nMeCN (L = N-(2,6-di{pyrazol-1-yl}pyrid-4-yl)acetamide; n = 1 or 2), [FeL2][ClO4]2·MeCN and [FeL2]X2·EtCN (X = BF4 or ClO4) are all isomorphous but exhibit a variety of spin state behaviours
Consumer Healthy Eating 2021 dataset
No full textThis dataset contains data on perceived compliance to the UK Eatwell guide (19 items) from a survey in 2021 of UK consumers (n=415). Additional scales for eating healthy foods were from Norman et al. 2010 (https://doi.org/10.1186/1479-5868-7-56), which include Change strategies (15 items), Enjoyment (7 items) and Environment (4 items). Demographic data (Type of Diet, Ethnicity, Gender and Age)
Mineral and biological ice-nucleating particles above the South East of the British Isles
No full textDataset associated to the publication: https://doi.org/10.1039/D1EA00003A. It contains the location, INP concentration, chemical composition, ice-nucleating density of active sites and bioaerosol concentrations of the samples used in this publication
Data set for ice nucleation by viruses and their potential for cloud glaciation
No full textIn order to effectively predict the formation of ice in clouds we need to know which subsets of aerosol particles are effective at nucleating ice, how they are distributed and where they are from. A large proportion of ice-nucleating particles (INPs) in many locations are likely of biological origin, and some INPs are extremely small being just tens of nanometers in size. The identity and sources of such INPs are not well characterized. Here, we show that several different types of virus particles can nucleate ice, with up to about one in twenty million virus particles able to nucleate ice at −20 °C. In terms of the impact on cloud glaciation, the ice-nucleating ability (the fraction which are ice nucleation active as a function of temperature) taken together with typical virus particle concentrations in the atmosphere lead to the conclusion that virus particles make a minor contribution to the atmospheric ice-nucleating particle population in the terrestrial influenced atmosphere. However, they cannot be ruled out as being important in the remote marine atmosphere. It is striking that virus particles have an ice-nucleating activity and further work should be done to explore other types of viruses for both their ice-nucleating potential and to understand the mechanism by which viruses nucleate ice
Switching between Magnetic Bloch and Néel Domain Walls with Anisotropy Modulations - dataset
No full textData from the paper "Switching between Magnetic Bloch and Néel Domain Walls with Anisotropy Modulations"
Data associated with 'The effect of forest-to-bog restoration on the hydrological functioning of raised and blanket bogs'
No full textThe abstract is for the dataset rather than the publication. The abstract of the paper based on this dataset can be found at https://doi.org/10.1002/eco.233
Data associated with 'Horizon: Microfluidic Platform for the Production of Therapeutic Microbubbles and Nanobubbles'
No full textMicrobubbles have a multitude of applications including as contrast agents in ultrasound imaging and as therapeutic drug delivery vehicles, with further scope for combining their diagnostic and therapeutic properties (known as theranostics). Microbubbles used clinically are commonly made by mechanical agitation or sonication methods, which offers little control over population size and dispersity. Further, clinically used microbubbles are yet to be used therapeutically and further research is needed to develop these theranostic agents. Here we present our microbubble production instrument “Horizon” which is a robust, portable, and user-friendly instrument, integrating the key components for producing MBs using microfluidic flow-focusing devices. In this paper we present the system design and specifications of Horizon, and the optimised protocols that have so far been used to produce MBs with specific properties. These include microbubbles with tailored size and low dispersity (monodisperse), microbubbles with a diameter ~2 µm which are more disperse but also produced in higher concentration, nanobubbles with diameters 100-600 nm, and therapeutic microbubbles with drug payloads for targeted delivery. Multiplexed chips were able to improve production rates up to sixteen-fold whilst maintaining production stability. This work shows that Horizon is a versatile instrument with potential for mass production and use across many research facilities, which could begin to bridge the gap between therapeutic microbubble research and clinical use
Consumer Healthy Eating 2019 dataset
No full textThis dataset contains data on perceived compliance to the UK Eatwell guide (15 items) and food consumption (11 items) from a survey in 2019 of UK consumers (n=301) . Demographic data (Type of Diet, Ethnicity, Gender and Age) and exercise duration were also collected
Consumer Healthy Eating and wellbeing 2021 dataset
Get PDFThis dataset contains data on perceived compliance to the UK Eatwell guide (19 items) and food wellbeing (20 items) from a survey in 2021 of UK consumers (n=409). Other variables include Snacking choice (3 items), Snacking practice (2 items), Packaging (3 items), eating behaviour (3 items). Demographic data (Type of Diet, Ethnicity, Gender and Age) and (perceived health, Mental health and exercise frequency) were also collected
Data associated with 'Multi-scale simulations of the T cell receptor reveal its lipid interactions, dynamics and the arrangement of its cytoplasmic region'
No full textThe T cell receptor (TCR-CD3) initiates T cell activation by binding to peptides of Major Histocompatibility Complexes (pMHC). The TCR-CD3 topology is well understood but the arrangement and dynamics of its cytoplasmic tails remains unknown, limiting our grasp of the signalling mechanism. Here, we use molecular dynamics simulations and modelling to investigate the entire TCR-CD3 embedded in a model membrane. Our study demonstrates conformational changes in the extracellular and transmembrane domains, and the arrangement of the TCR-CD3 cytoplasmic tails. The cytoplasmic tails formed highly interlaced structures while some tyrosines within the immunoreceptor tyrosine-based activation motifs (ITAMs) penetrated the hydrophobic core of the membrane. Interactions between the cytoplasmic tails and phosphatidylinositol phosphates lipids in the inner membrane leaflet led to the formation of a distinct anionic lipid fingerprint around the TCR-CD3. These results increase our understanding of the TCR-CD3 dynamics and the importance of membrane lipids in regulating T cell activation