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Probiotics in reducing the incidence of vaginal infections in woman
Uvod: Vaginalni mikrobiom, kjer prevladujejo laktobacili, predstavlja ključno zaščito pred vaginalnimi okužbami, kot je vulvovaginalna kandidiaza (VVC). Neravnovesje mikrobiote vodi v povečano pojavnost teh okužb. Uporaba probiotikov, zlasti sevov laktobacilov, so obetaven dopolnilni pristop za njihovo preprečevanje in zdravljenje. Namen zaključnega dela je na podlagi pregleda literature analizirati vpliv uživanja probiotikov na zmanjšanje pojavnosti vaginalnih infekcij pri ženskah.
Metode: Izvedli smo pregled znanstvene literature v podatkovnih bazah PubMed, SAGE in Cochrane Library. Uporabili smo PRISMA diagram za prikaz izbora virov. Vključili smo sistematične preglede, randomizirane kontrolirane raziskave in kvazieksperimentalno raziskavo.
Rezultati: Vključenih je bilo deset raziskav: dve sistematični analizi, sedem randomiziranih s placebom kontroliranih raziskav in ena kvazieksperimentalna. Večina je potrdila, da so probiotiki učinkoviti pri zmanjševanju simptomov VVC ter preprečevanju ponovitev, zlasti v kombinaciji s standardnim antimikotičnim zdravljenjem.
Diskusija in zaključek: Uporaba probiotikov, predvsem sevov laktobacilov, kaže potencial pri zdravljenju in preprečevanju VVC, predvsem pri nenosečih ženskah. Učinkovitost je odvisna od seva, načina uporabe in posameznih dejavnikov. Potrebne so dodatne raziskave, zlasti pri nosečnicah, zaradi pomanjkanja raziskav na tem področju.Introduction: The vaginal microbiome, dominated by lactobacilli, plays a key protective role against vaginal infections such as vulvovaginal candidiasis (VVC). An imbalance in the microbiota leads to an increased incidence of these infections. The use of probiotics, particularly lactobacillus strains, represents a promising complementary approach for their prevention and treatment. The aim of this thesis is to analyse the impact of probiotic consumption on the reduction of vaginal infections in women based on a review of the literature.
Methods: We conducted a review of scientific literature using the databases PubMed, SAGE, and the Cochrane Library. A PRISMA diagram was used to illustrate the selection process of the sources. We included systematic reviews, randomized controlled trials, and one quasi-experimental study.
Results: A total of ten studies were included: two systematic reviews, seven randomized placebo-controlled trials, and one quasi-experimental study. Most of the studies confirmed that probiotics are effective in reducing the symptoms of VVC and preventing recurrences, especially when used in combination with standard antifungal treatment.
Discussion and Conclusion: The use of probiotics, particularly lactobacillus strains, shows potential in the treatment and prevention of VVC, especially in non-pregnant women. Effectiveness depends on the specific strain, mode of administration, and individual factors. Further research is needed, particularly in pregnant women, due to the lack of studies in this area
Analysis and optimization of systems for monitoring it devices and services in a selected organization
Naloga obravnava problem izbora rešitve nadzornega sistema, ki bo nadomestil najmanj dve obstoječi rešitvi v izbranem podjetju. Cilji naloge so opraviti analizo obstoječih treh rešitev z vidika funkcionalnosti in stroškov, oblikovati predlog enotne rešitve nadzornega sistema z uporabo najbolj primerne rešitve, ter podati oceno izvedljivosti takega posega in ga predstaviti vodstvu izbranega podjetja. Z raziskavo najboljših praks pri vzpostavitvi nadzornih sistemov in analizo funkcionalnosti obstoječih rešitev smo z uporabo metode in orodja za podporo večfaktorskemu odločanju, DEXi, izpostavili oceno ustreznosti posamičnih treh rešitev. Z opravljeno analizo stroškov in koristi smo rešitve primerjali z namenom priprave argumentov za odločitev za izbor ene rešitve, ki bo nadomestila ostali dve. Izbrano podjetje ni imelo jasne slike glede razlik pri rešitvah nadzornih sistemov, zato smo si zastavili raziskovalno vprašanje: »Ali so rešitve za nadzor informacijskih podatkovnih centrov enakovredne?«. Raziskava je pokazala, da temu ni tako. V izbranem podjetju so na podlagi naše raziskave bolj suvereno sprejeli odločitev glede izbora rešitve nadzornega sistema. Raziskavo je mogoče dopolniti še z vključitvijo razširitev obstoječih rešitev, kot tudi s primerjavo drugih uveljavljenih rešitev za nadzor podatkovnih centrov.This study addresses the problem of selecting a monitoring system solution that should replace at least two of the existing solutions within the selected company. The objectives of this study were three fold. First was to perform an analysis of the existing three monitoring systems from the perspective of functionality and costs. The second objective was to formulate a proposal for a unified monitoring system using the most suitable solution. The third objective was to provide an assessment of the feasibility of such consolidation and present it to the company\u27s IT management. By researching best practices and available documentation of the three solutions, we were able to gather enough information to use it with the multifactorial decision support method and tool named DEXi. This method clearly showed that one of the solutions stands out. By further cost-benefit analysis, we compared the solutions with the aim of preparing clear arguments for the decision to select one solution that will replace the other two. As the selected company was unclear of the differences in monitoring solutions, we proposed the research question to be: »Are solutions for monitoring data centers equivalent?«. The research clearly showed that this is not the case. The selected company can make a more confident decision regarding the selection of the appropriate monitoring solution. It is possible to further expand the study by including the modular expansions of the monitoring solutions as well as comparing them with more monitoring solutions
Comparision of triage of psychiatric emergency call by an emergency medical dispatcher with artificial intelligence
Triažiranje nujnih klicev psihiatričnih pacientov je ključno za hitro in ustrezno ukrepanje, saj napačna ocena nujnosti vodi v resne posledice za paciente in neučinkovito rabo virov. V magistrskem delu preučujemo učinkovitost umetne inteligence v primerjavi z zdravstvenim dispečerjem pri triažiranju nujnih klicev s psihiatrično simptomatiko.Triage of emergency calls from psychiatric patients is crucial for timely and appropriate intervention, as incorrect urgency assessment can lead to serious consequences for patients and inefficient use of resources. This study examines the effectiveness of artificial intelligence compared to emergency medical dispatcher in triaging emergency psychiatric calls
Stigmatisation of women with postpartum depression
Uvod: Poporodno depresijo uvrščamo med duševne motnje, ki se lahko pojavijo med nosečnostjo ali po porodu, skupaj s poporodno otožnostjo, anksioznostjo in poporodno psihozo. Predstavlja pomemben javnozdravstveni problem, ki vpliva tako na žensko s poporodno depresijo kot na njeno družino. Podobno kot druge duševne motnje je bila tudi poporodna depresija dolgo napačno razumljena in stigmatizirana. Namen zaključnega dela je raziskati problem stigmatizacije žensk s poporodno depresijo, na podlagi pregleda literature.Introduction: Postpartum depression is classified among mental disorders that can occur during pregnancy or after childbirth, along with postpartum blues, anxiety, and postpartum psychosis. It represents a significant public health issue that affects both the mother and the family. Like other mental disorders, postpartum depression has long been misunderstood and stigmatized. The aim of this thesis is to explore the problem of stigmatization of women with postpartum depression based on a review of the literature
Comparison of environmental impact between the use of diesel engine and gas turbine for electricity production at the Brestanica Thermal Power Plant
V sodobnem svetu je proizvodnja električne energije nujna zaradi bolj množične uporabe električnih naprav in vse večjega povpraševanja po energiji. Podnebne spremembe se lahko štejejo za enega najbolj perečih problemov, s katerimi se trenutno sooča svet. Nekatere metode pridobivanja električne energije s premogom, nafto, zemeljskim plinom povzročajo neizogibne emisije toplogrednih plinov in številne negativne učinke na okolje. Temperatura narašča, dviga se morska gladina in še ena težava, ki je povezana s podnebnimi spremembami, je izčrpavanje fosilnih goriv. Vsem proizvodnjam je pomembno, da svojo energijo proizvajajo na učinkovit način in poskušajo zmanjšati njen vpliv na okolje.
V magistrskem delu smo analizirali in primerjali uporabo različnih pogonov v Termoelektrarni Brestanica. Želeli smo ugotoviti, kakšen vpliv ima uporaba dizelskega motorja v proizvodnjito smo primerjali s trenutnimi pogoni, ki jih imajo plinski bloki v Brestanici. Ugotovili smo, da ima dizelski motor krajši odzivni čas pri zagonu, zato lahko posledično tudi zmanjšamo emisijske vplive na okolje.In the modern world, electricity production is essential due to the widespread use of electrical devices and the increasing demand for energy. Climate change can be considered one of the most pressing issues facing the world today. Some methods of generating electricity using coal, oil, natural gas result in unavoidable greenhouse gas emissions and numerous negative environmental impacts. Temperatures are rising, sea levels are increasing, and another issue associated with climate change is the depletion of fossil fuels. It is crucial for all industries to produce their energy efficiently and attempt to reduce its impact on the environment.
In this master\u27s thesis, we analyzed and compared the use of different propulsion systems at the Brestanica Thermal Power Plant. We aimed to determine the impact of using a diesel engine in production and compared it to the current propulsion systems used in the Brestanica gas blocks. We found that the diesel engine has a shorter response time during startup, which consequently allows for a reduction in environmental emissions
Machining technology and construction of the clamping device for lower fork plate
Magistrsko delo obsega razvoj tehnologije mehanske obdelave in konstruiranje pripadajoče vpenjalne priprave za izdelka, ki služi kot pilotni projekt za prodiranje na trg mehanske obdelave aluminijastih odkovkov. Cilj naloge je vzpostaviti proizvodne pogoje, primerne za serijsko proizvodnjo, ob upoštevanju znanih in znotraj naloge opredeljenih omejitev. Za izdelavo sta bili uporabljeni programski okolji SolidWorks in SolidCAM ter metodi Poka Yoke in SMED. V delu so prikazane prednosti uporabe teh metod na vpenjalni pripravi in namenskih orodij za proces obdelave.This master’s thesis focuses on the development of mechanical processing technology and the construction of the corresponding clamping device for the product, serving as a pilot project for penetrating the mechanical processing of aluminum forgings market. The objective is to establish production conditions optimized for serial production, considering predefined constraints. The software environments SolidWorks and SolidCAM, as well as Poka Yoke and SMED methods, are employed. The study highlights the advantages of utilizing these methods for clamping device and dedicated tools during processing
Business growth strategy through digital marketing: the example of a small business
V magistrskem delu obravnavamo pomen digitalnega marketinga kot ključnega orodja za rast in razvoj malega podjetja, ki deluje na slovenskem trgu. S hitro digitalizacijo poslovanja in spremenjenim vedenjem potrošnikov postaja učinkovita spletna prisotnost vse pomembnejša. Glavni poudarek naloge je na praktičnem preizkusu različnih strategij digitalnega marketinga, kot so SEO optimizacija, plačljivo oglaševanje, vsebinski marketing in optimizacija uporabniške izkušnje v spletni trgovini, ki temelji na platformi WooCommerce. S pomočjo eksperimenta v izbranem malem podjetju analiziramo učinke teh pristopov na spletno prodajo, konverzije ter splošno prepoznavnost podjetja. Na podlagi dobljenih rezultatov damo konkretna priporočila za nadaljnjo optimizacijo spletnega nastopa in digitalne rasti podjetja.This master’s thesis explores the role of digital marketing as a key tool for the growth and development of a small business operating in the Slovenian market. With the rapid digitalization of commerce and shifting consumer behavior, having an effective online presence has become essential. The main focus of the thesis is a practical test of various digital marketing strategies, such as SEO optimization, paid advertising, content marketing, and user experience improvements within a WooCommerce-based online store. Using an experiment within the selected company, we analyze the impact of these approaches on online sales, conversions, and brand awareness. Based on the findings, the thesis provides concrete recommendations for further optimization of the company’s digital strategy and sustainable growth
The impact of improper storage of dangerous goods on the environment, human health and safety
V diplomskem delu je obravnavan vpliv nepravilnega skladiščenja nevarnega blaga na okolje, zdravje ljudi in varnost. Nevarne snovi predstavljajo pomembno tveganje zaradi svoje kemijske, fizikalne ali biološke nevarnosti, zato so pravilni postopki skladiščenja ključni za preprečevanje nesreč, onesnaženja in ogrožanja prebivalstva. V teoretičnem delu so predstavljeni osnovni pojmi, zakonodaja, standardi ter zahteve, ki določajo varno ravnanje z nevarnimi snovmi. Poseben poudarek je namenjen skladiščenju radioaktivnih odpadkov, zlasti vprašanju umeščanja odlagališča na Trgovski gori, kjer so analizirani tehnični, okoljski in varnostni vidiki ter mnenja lokalne skupnosti. V empiričnem delu je izvedena anketa, s katero je bila ocenjena zaznava tveganj in stopnja sprejemljivosti lokacije med prebivalci. Rezultati kažejo na visoko stopnjo zaskrbljenosti zaradi potresne ogroženosti, hidroloških vplivov in bližine reke Une ter naselij. Ugotovitve diplomskega dela poudarjajo potrebo po preglednem načrtovanju, izbiri primernejše lokacije in celovitem vključevanju javnosti v postopke odločanja.The thesis examines the impact of improper storage of hazardous materials on the environment, human health, and safety. Hazardous substances pose significant risks due to their chemical, physical, or biological properties, making proper storage procedures essential to prevent accidents, pollution, and threats to local populations. The theoretical part presents key concepts, legislation, standards, and requirements related to the safe handling of dangerous goods. Special emphasis is placed on the storage of radioactive waste, particularly the proposed repository at Trgovska Gora, where technical, environmental, and safety aspects, as well as the perceptions of the local community, are analysed. In the empirical part, a survey was conducted to assess risk perception and the level of acceptance among residents. The results show a high degree of concern related to seismic risks, hydrological impacts, and the proximity of the Una River and nearby settlements. The findings highlight the need for transparent planning, the selection of a more suitable location, and comprehensive public involvement in decision-making processes
Readability and vagueness of privacy policies in mHealth applications
Privacy policies are intended to inform users about how their data is collected and processed, but they are often shaped by legalmotivations that can reduce their clarity. This study analyzes English-language privacy policies frommedical and healthrelated apps in 10 Western-influenced countries to assess their readability and vagueness. From an initial dataset of 3,992 policies, 713 were selected for analysis. Readability and vague language were quantified using standard indices. The findings reveal significant regional differences in both readability and vagueness. Notably, shorter policies tended to be less readable but also less vague than longer ones. This study represents a pioneering effort, as it is the first of its kind to specifically address the issue of vagueness in mHealth applications’ privacy policies. The results of this study imply that the privacy policies are way too long and complex to read and too vague to uncover the actual data handling and processing practices